Jonathan Brett

Research Fellow

Jonathan is a staff specialist in clinical pharmacology, toxicology and addiction medicine at St. Vincent's Hospital. He is a clinical lecturer at UNSW and USyd and holds an academic appointment at the Centre for Big Data Research in Health. He sits on the Drug Utilisation Sub Committee of the PBAC and is on the editorial board of NSW Therapeutic Advisory Group.

Journal articles
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Brett J; Wylie C; Brown J, 2020, 'A case of significant hypotension following a human ingestion of veterinary pimobendan', Clinical Toxicology, vol. 58, pp. 146 - 148, http://dx.doi.org/10.1080/15563650.2019.1613550
2020
Stefani M; Roberts DM; Brett J, 2020, 'High-dose insulin euglycemic therapy to treat cardiomyopathy associated with massive venlafaxine overdose', Clinical Toxicology, vol. 58, pp. 299 - 300, http://dx.doi.org/10.1080/15563650.2019.1638930
2020
Chalmers K; Pearson SA; Badgery-Parker T; Brett J; Scott IA; Elshaug AG, 2019, 'Measuring 21 low-value hospital procedures: Claims analysis of Australian private health insurance data (2010-2014)', BMJ Open, vol. 9, http://dx.doi.org/10.1136/bmjopen-2018-024142
2019
Gisev N; Brett J; Peacock A, 2019, 'Extra-medical use of antipsychotics: what can be learnt from experiences with other prescription medicines?', Addiction, http://dx.doi.org/10.1111/add.14823
2019
Sandaradura I; Brett J; Milliken S, 2019, 'A study of piperacillin pharmacokinetics during febrile neutropenia', Journal of Infection and Chemotherapy
2019
Chalmers K; Badgery-Parker T; Pearson SA; Brett J; Scott I; Elshaug AG, 2019, 'Measuring 21 low-value health care procedures in Australian private health insurance claims data (2010 – 2014)', BMJ
2019
Brett J; Anthony C; Day R, 2019, 'Off-label quetiapine prescribing in general hospital inpatients', Journal of Pharmacy Practice and Research
2019
Brett J; Wylie C; Raubenheimer J; Isbister G; Buckley N, 2019, 'The relative lethal toxicity of pharmaceutical and illicit substances; A 16-year study of the Greater Newcastle Hunter Area, Australia', British journal of clinical
2019
Chalmers K; Badgery-Parker T; Pearson SA; Brett J; Scott IA; Elshaug AG, 2018, 'Developing indicators for measuring low-value care: Mapping Choosing Wisely recommendations to hospital data', BMC Research Notes, vol. 11, http://dx.doi.org/10.1186/s13104-018-3270-4
2018
Brett J; Zoega H; Buckley NA; Daniels BJ; Elshaug AG; Pearson SA, 2018, 'Choosing wisely? Quantifying the extent of three low value psychotropic prescribing practices in Australia', BMC Health Services Research, vol. 18, pp. 1009, http://dx.doi.org/10.1186/s12913-018-3811-5
2018
Badgery-Parker T; Pearson SA; Chalmers K; Brett J; Scott IA; Dunn S; Onley N; Elshaug AG, 2018, 'Low-value care in Australian public hospitals: Prevalence and trends over time', BMJ Quality and Safety, vol. 28, pp. 205 - 214, http://dx.doi.org/10.1136/bmjqs-2018-008338
2018
Brett J; Schaffer A; Dobbins T; Buckley NA; Pearson SA, 2018, 'The impact of permissive and restrictive pharmaceutical policies on quetiapine dispensing: Evaluating a policy pendulum using interrupted time series analysis', Pharmacoepidemiology and Drug Safety, vol. 27, pp. 439 - 446, http://dx.doi.org/10.1002/pds.4408
2018
Karanges EA; Buckley NA; Brett J; Blanch B; Litchfield M; Degenhardt L; Pearson SA, 2018, 'Trends in opioid utilisation in Australia, 2006-2015: Insights from multiple metrics', Pharmacoepidemiology and Drug Safety, vol. 27, pp. 504 - 512, http://dx.doi.org/10.1002/pds.4369
2018
Brett J; Maust DT; Bouck Z; Ignacio RV; Mecredy G; Kerr EA; Bhatia S; Elshaug AG; Pearson SA, 2018, 'Benzodiazepine Use in Older Adults in the United States, Ontario, and Australia from 2010 to 2016', Journal of the American Geriatrics Society, vol. 66, pp. 1180 - 1185, http://dx.doi.org/10.1111/jgs.15292
2018
Brett J; Elshaug AG; Bhatia RS; Chalmers K; Badgery-Parker T; Pearson SA, 2017, 'A methodological protocol for selecting and quantifying low-value prescribing practices in routinely collected data: An Australian case study', Implementation Science, vol. 12, http://dx.doi.org/10.1186/s13012-017-0585-9
2017
Brett J; Daniels B; Karanges EA; Buckley NA; Schneider C; Nassir A; McLachlan AJ; Pearson SA, 2017, 'Psychotropic polypharmacy in Australia, 2006 to 2015: a descriptive cohort study', British Journal of Clinical Pharmacology, vol. 83, pp. 2581 - 2588, http://dx.doi.org/10.1111/bcp.13369
2017
Brett J; Karanges EA; Daniels B; Buckley NA; Schneider C; Nassir A; Zoega H; McLachlan AJ; Pearson SA, 2017, 'Psychotropic medication use in Australia, 2007 to 2015: Changes in annual incidence, prevalence and treatment exposure', Australian and New Zealand Journal of Psychiatry, vol. 51, pp. 990 - 999, http://dx.doi.org/10.1177/0004867417721018
2017
Brett J; Murnion B, 2015, 'Management of benzodiazepine misuse and dependence', Australian Prescriber, vol. 38, pp. 152 - 155, http://dx.doi.org/10.18773/austprescr.2015.055
2015
Brett J, 2015, 'Concerns about quetiapine', Australian Prescriber, vol. 38, pp. 95 - 97, http://dx.doi.org/10.18773/austprescr.2015.032
2015
Brett J; Murnion B, 2015, 'Pregabalin to treat ciguatera fish poisoning', Clinical Toxicology, vol. 53, pp. 588, http://dx.doi.org/10.3109/15563650.2015.1052499
2015
Brett J, 2015, 'Comments: Letters to the editor: Concerns about quetiapine', Australian Prescriber, vol. 38, pp. 189 - 190
2015
Montebello ME; Brett B, 2015, 'Misuse and associated harms of quetiapine and other atypical antipsychotics', Current Topics in Behavioral Neurosciences, vol. 34, pp. 1 - 15, http://dx.doi.org/10.1007/7854_2015_424
2015
Brett J; Dawson AH; Brown JA, 2014, 'Clenbuterol toxicity: A NSW Poisons Information Centre experience', Medical Journal of Australia, vol. 200, pp. 219 - 221, http://dx.doi.org/10.5694/mja13.10982
2014
Baysari M; Brett J; Lam V; Milder T; Killen L; Chau AMT; McMullan B; Harkness J; Marriot D; Day R, 2013, 'Pneumonia Severity Scores and Prescribing Antibiotics for Community-Acquired Pneumonia at an Australian Hospital', Journal of Pharmacy Practice and Research, vol. 43, pp. 97 - 101, http://dx.doi.org/10.1002/j.2055-2335.2013.tb00228.x
2013
Wong C; Kumar SS; Graham GG; Begg EJ; Chin P; Brett J; Ray J; Marriott D; Williams KM; Day RO, 2013, 'Comparing dose prediction software used to manage gentamicin dosing', Internal Medicine Journal, vol. 43, pp. 519 - 525, http://dx.doi.org/10.1111/imj.12067
2013
Brett J; Chong O; Graham GG; Ray J; Marriott D; Williams KM; Day RO, 2013, 'Antifungal Use and Therapeutic Monitoring of Plasma Concentrations of Itraconazole in Heart and Lung Transplantation Patients.', Therapeutic Drug Monitoring, vol. 35, pp. 133 - 136, http://dx.doi.org/10.1097/FTD.0b013e318275fe69
2013
Brett J, 2012, 'Why have prison needle exchange programmes not yet been rolled out in the UK?', BMJ (Online), vol. 345, http://dx.doi.org/10.1136/bmj.e6211
2012
Baysari MT; Tang T; Brett J; Day RO, 2012, 'Implementation of revised aminoglycoside guidelines: Australian hospitals 'left in the lurch'', Journal of Pharmacy Practice and Research, vol. 42, pp. 178 - 179, http://dx.doi.org/10.1002/j.2055-2335.2012.tb00163.x
2012
Lipworth WL; Kerridge IH; Brett J; Day RO, 2011, 'How clinical and resaerch failures lead to suboptimal prescribing: the example of chronic gout', British Medical Journal, vol. 343, pp. 1 - 3, http://dx.doi.org/10.1136/bmj.d7459
2011
Lipworth WL; Kerridge I; Brett J; Day R, 2011, 'How clinical and research failures lead to suboptimal prescribing: the example of chronic gout.', British Medical Journal, vol. 343, pp. d7459, http://dx.doi.org/10.1136/bmj.d7459
2011
Book Chapters
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Roberts DM; Brett J, 2014, 'Clinical management of acute OP pesticide poisoning', in , pp. 141 - 175, http://dx.doi.org/10.1007/978-1-4471-5625-3_6
2014
Reports
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Lukins TR; Pett SL; Brett J, 2013, Is it worth the weight?
2013

Gustav Nossal Award for top ranking NH&MRC Clinical Research Postgraduate Scholarship applicant nationally – 2015.
NSW Aboriginal Health Award for integrated planning and service delivery – 2014.
Aboriginal Drug and Alcohol Network (AH&MRC) project of the year award – 2014.
Registrar of the year award: St. Vincent’s Hospital, Sydney - 2012
Final Year Medal – Goyder Scholarship for Clinical Excellence in Medicine and Surgery- 2005

IHIF Grant: Pharmacogenomics in mental health

IHIF Grant: Take home naloxone in Emergency Departments