Stuart Tangye

Conjoint Professor

Fields of research:  Immunology

Research Interests:  Human immunology, cellular immunology, primary immunodeficiencies

Qualifications: B App Sci (hons), PhD

Society & Memberships:  Australasian Society of Immunology, Australasion Society of Clinical Immunology and Allergy, AAI, Henry Kunkel Society

http://www.garvan.org.au/research/immunology/immunobiology-and-immunodeficiency

 

 

 

publications

Journal articles
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Tangye SG; Al-Herz W; Bousfiha A; Chatila T; Cunningham-Rundles C; Etzioni A; Franco JL; Holland SM; Klein C; Morio T; Ochs HD; Oksenhendler E; Picard C; Puck J; Torgerson TR; Casanova JL; Sullivan KE, 2020, 'Human Inborn Errors of Immunity: 2019 Update on the Classification from the International Union of Immunological Societies Expert Committee', Journal of Clinical Immunology, http://dx.doi.org/10.1007/s10875-019-00737-x
2020
Bucciol G; Pillay B; Casas-Martin J; Delafontaine S; Proesmans M; Lorent N; Coolen J; Tousseyn T; Bossuyt X; Ma CS; Schrijvers R; Tangye SG; Moens L; Meyts I, 2020, 'Systemic Inflammation and Myelofibrosis in a Patient with Takenouchi-Kosaki Syndrome due to CDC42 Tyr64Cys Mutation', Journal of Clinical Immunology, http://dx.doi.org/10.1007/s10875-020-00742-5
2020
Jouanguy E; Béziat V; Mogensen TH; Casanova JL; Tangye SG; Zhang SY, 2020, 'Human inborn errors of immunity to herpes viruses', Current Opinion in Immunology, vol. 62, pp. 106 - 122, http://dx.doi.org/10.1016/j.coi.2020.01.004
2020
Bousfiha A; Jeddane L; Picard C; Al-Herz W; Ailal F; Chatila T; Cunningham-Rundles C; Etzioni A; Franco JL; Holland SM; Klein C; Morio T; Ochs HD; Oksenhendler E; Puck J; Torgerson TR; Casanova JL; Sullivan KE; Tangye SG, 2020, 'Human Inborn Errors of Immunity: 2019 Update of the IUIS Phenotypical Classification', Journal of Clinical Immunology, http://dx.doi.org/10.1007/s10875-020-00758-x
2020
Tangye SG; Latour S, 2020, 'Primary immunodeficiencies reveal the molecular requirements for effective host defense against EBV infection', Blood, vol. 135, pp. 644 - 655, http://dx.doi.org/10.1182/blood.2019000928
2020
Tangye SG, 2020, 'Genetic susceptibility to EBV infection: insights from inborn errors of immunity', Human Genetics, http://dx.doi.org/10.1007/s00439-020-02145-3
2020
Tangye SG; Ma CS, 2020, 'Regulation of the germinal center and humoral immunity by interleukin-21', The Journal of experimental medicine, vol. 217, http://dx.doi.org/10.1084/jem.20191638
2020
Tangye SG; Al-Herz W; Bousfiha A; Chatila T; Cunningham-Rundles C; Etzioni A; Franco JL; Holland SM; Klein C; Morio T; Ochs HD; Oksenhendler E; Picard C; Puck J; Torgerson TR; Casanova JL; Sullivan KE, 2020, 'Correction to: Human Inborn Errors of Immunity: 2019 Update on the Classification from the International Union of Immunological Societies Expert Committee (Journal of Clinical Immunology, (2020), 10.1007/s10875-019-00737-x)', Journal of Clinical Immunology, http://dx.doi.org/10.1007/s10875-020-00763-0
2020
Lau A; Avery DT; Jackson K; Lenthall H; Volpi S; Brigden H; Russell AJ; Bier J; Reed JH; Smart JM; Cole T; Choo S; Gray PE; Berglund LJ; Hsu P; Wong M; O'Sullivan M; Boztug K; Meyts I; Uzel G; Notarangelo LD; Brink R; Goodnow CC; Tangye SG; Deenick EK, 2020, 'Activated PI3Kδ breaches multiple B cell tolerance checkpoints and causes autoantibody production', The Journal of experimental medicine, vol. 217, http://dx.doi.org/10.1084/jem.20191336
2020
Li J; Ritelli M; Ma CS; Rao G; Habib T; Corvilain E; Bougarn S; Cypowyj S; Grodecká L; Lévy R; Béziat V; Shang L; Payne K; Avery DT; Migaud M; Boucherit S; Boughorbel S; Guennoun A; Chrabieh M; Rapaport F; Bigio B; Itan Y; Boisson B; Cormier-Daire V; Syx D; Malfait F; Zoppi N; Abel L; Freiberger T; Dietz HC; Marr N; Tangye SG; Colombi M; Casanova JL; Puel A, 2019, 'Chronic mucocutaneous candidiasis and connective tissue disorder in humans with impaired JNK1-dependent responses to IL-17A/F and TGF-β', Science Immunology, vol. 4, http://dx.doi.org/10.1126/sciimmunol.aax7965
2019
Anzilotti C; Swan DJ; Boisson B; Deobagkar-Lele M; Oliveira C; Chabosseau P; Engelhardt KR; Xu X; Chen R; Alvarez L; Berlinguer-Palmini R; Bull KR; Cawthorne E; Cribbs AP; Crockford TL; Dang TS; Fearn A; Fenech EJ; de Jong SJ; Lagerholm BC; Ma CS; Sims D; van den Berg B; Xu Y; Cant AJ; Kleiner G; Leahy TR; de la Morena MT; Puck JM; Shapiro RS; van der Burg M; Chapman JR; Christianson JC; Davies B; McGrath JA; Przyborski S; Santibanez Koref M; Tangye SG; Werner A; Rutter GA; Padilla-Parra S; Casanova JL; Cornall RJ; Conley ME; Hambleton S, 2019, 'An essential role for the Zn 2+ transporter ZIP7 in B cell development', Nature Immunology, vol. 20, pp. 350 - 361, http://dx.doi.org/10.1038/s41590-018-0295-8
2019
Moran I; Avery DT; Payne K; Lenthall H; Davies EG; Burns S; Ip W; Oleastro MM; Reisli I; Guner S; Keles S; Notarangelo L; Deenick EK; Goodnow CC; Zahra D; Brink R; Wong M; Tangye SG; Ma CS; Phan TG, 2019, 'B cell–intrinsic requirement for STK4 in humoral immunity in mice and human subjects', Journal of Allergy and Clinical Immunology, vol. 143, pp. 2302 - 2305, http://dx.doi.org/10.1016/j.jaci.2019.02.010
2019
Koutsakos M; Illing PT; Nguyen THO; Mifsud NA; Crawford JC; Rizzetto S; Eltahla AA; Clemens EB; Sant S; Chua BY; Wong CY; Allen EK; Teng D; Dash P; Boyd DF; Grzelak L; Zeng W; Hurt AC; Barr I; Rockman S; Jackson DC; Kotsimbos TC; Cheng AC; Richards M; Westall GP; Loudovaris T; Mannering SI; Elliott M; Tangye SG; Wakim LM; Rossjohn J; Vijaykrishna D; Luciani F; Thomas PG; Gras S; Purcell AW; Kedzierska K, 2019, 'Human CD8 + T cell cross-reactivity across influenza A, B and C viruses', Nature Immunology, vol. 20, pp. 613 - 625, http://dx.doi.org/10.1038/s41590-019-0320-6
2019
Worley L; Tangye SG; Ma CS, 2019, 'What can primary immunodeficiencies teach us about Th9 cell differentiation and function?', Immunology and Cell Biology, vol. 97, pp. 380 - 388, http://dx.doi.org/10.1111/imcb.12215
2019
Pillay BA; Avery DT; Smart JM; Cole T; Choo S; Chan D; Gray PE; Frith K; Mitchell R; Phan TG; Wong M; Campbell DE; Hsu P; Ziegler JB; Peake J; Alvaro F; Picard C; Bustamante J; Neven B; Cant AJ; Uzel G; Arkwright PD; Casanova JL; Su HC; Freeman AF; Shah N; Hickstein DD; Tangye SG; Ma CS, 2019, 'Hematopoietic stem cell transplant effectively rescues lymphocyte differentiation and function in DOCK8-deficient patients', JCI Insight, vol. 4, http://dx.doi.org/10.1172/jci.insight.127527
2019
Tangye SG; Bier J; Lau A; Nguyen T; Uzel G; Deenick EK, 2019, 'Immune Dysregulation and Disease Pathogenesis due to Activating Mutations in PIK3CD—the Goldilocks’ Effect', Journal of Clinical Immunology, vol. 39, pp. 148 - 158, http://dx.doi.org/10.1007/s10875-019-00612-9
2019
French MA; Tangye SG, 2019, 'The Next Generation of Diagnostic Tests for Primary Immunodeficiency Disorders.', J Infect Dis, http://dx.doi.org/10.1093/infdis/jiz230
2019
Moens L; Gouwy M; Bosch B; Pastukhov O; Nieto-Patlàn A; Siler U; Bucciol G; Mekahli D; Vermeulen F; Desmet L; Maebe S; Flipts H; Corveleyn A; Moshous D; Philippet P; Tangye SG; Boisson B; Casanova JL; Florkin B; Struyf S; Reichenbach J; Bustamante J; Notarangelo LD; Meyts I, 2019, 'Human DOCK2 Deficiency: Report of a Novel Mutation and Evidence for Neutrophil Dysfunction', Journal of Clinical Immunology, vol. 39, pp. 298 - 308, http://dx.doi.org/10.1007/s10875-019-00603-w
2019
Ma CS; Tangye SG, 2019, 'Flow Cytometric-Based Analysis of Defects in Lymphocyte Differentiation and Function Due to Inborn Errors of Immunity', Frontiers in Immunology, vol. 10, pp. 2108, http://dx.doi.org/10.3389/fimmu.2019.02108
2019
Bier J; Rao G; Payne K; Brigden H; French E; Pelham SJ; Lau A; Lenthall H; Edwards ESJ; Smart JM; Cole TS; Choo S; Joshi AY; Abraham RS; O'Sullivan M; Boztug K; Meyts I; Gray PE; Berglund LJ; Hsu P; Wong M; Holland SM; Notarangelo LD; Uzel G; Ma CS; Brink R; Tangye SG; Deenick EK, 2019, 'Activating mutations in PIK3CD disrupt the differentiation and function of human and murine CD4+ T cells', Journal of Allergy and Clinical Immunology, vol. 144, pp. 236 - 253, http://dx.doi.org/10.1016/j.jaci.2019.01.033
2019
Frith K; Joly AL; Ma CS; Tangye SG; Lohse Z; Seitz C; Verge CF; Andersson J; Gray P, 2019, 'The FOXP3Δ2 isoform supports Treg cell development and protects against severe IPEX syndrome', Journal of Allergy and Clinical Immunology, vol. 144, pp. 317 - 320.e8, http://dx.doi.org/10.1016/j.jaci.2019.03.003
2019
Khourieh J; Rao G; Habib T; Avery DT; Lefèvre-Utile A; Chandesris MO; Belkadi A; Chrabieh M; Alwaseem H; Grandin V; Sarrot-Reynauld F; Sénéchal A; Lortholary O; Kong XF; Boisson-Dupuis S; Picard C; Puel A; Béziat V; Zhang Q; Abel L; Molina H; Marr N; Tangye SG; Casanova JL; Boissona B, 2019, 'A deep intronic splice mutation of STAT3 underlies hyper IgE syndrome by negative dominance', Proceedings of the National Academy of Sciences of the United States of America, vol. 116, pp. 16463 - 16472, http://dx.doi.org/10.1073/pnas.1901409116
2019
Zammit NW; Siggs OM; Gray PE; Horikawa K; Langley DB; Walters SN; Daley SR; Loetsch C; Warren J; Yap JY; Cultrone D; Russell A; Malle EK; Villanueva JE; Cowley MJ; Gayevskiy V; Dinger ME; Brink R; Zahra D; Chaudhri G; Karupiah G; Whittle B; Roots C; Bertram E; Yamada M; Jeelall Y; Enders A; Clifton BE; Mabbitt PD; Jackson CJ; Watson SR; Jenne CN; Lanier LL; Wiltshire T; Spitzer MH; Nolan GP; Schmitz F; Aderem A; Porebski BT; Buckle AM; Abbott DW; Ziegler JB; Craig ME; Benitez-Aguirre P; Teo J; Tangye SG; King C; Wong M; Cox MP; Phung W; Tang J; Sandoval W; Wertz IE; Christ D; Goodnow CC; Grey ST, 2019, 'Denisovan, modern human and mouse TNFAIP3 alleles tune A20 phosphorylation and immunity', Nature Immunology, vol. 20, pp. 1299 - 1310, http://dx.doi.org/10.1038/s41590-019-0492-0
2019
Edwards ESJ; Bier J; Cole TS; Wong M; Hsu P; Berglund LJ; Boztug K; Lau A; Gostick E; Price DA; O'Sullivan M; Meyts I; Choo S; Gray P; Holland SM; Deenick EK; Uzel G; Tangye SG, 2019, 'Activating PIK3CD mutations impair human cytotoxic lymphocyte differentiation and function and EBV immunity', Journal of Allergy and Clinical Immunology, vol. 143, pp. 276 - 291.e6, http://dx.doi.org/10.1016/j.jaci.2018.04.030
2019
Tangye SG; Bucciol G; Casas-Martin J; Pillay B; Ma CS; Moens L; Meyts I, 2019, 'Human inborn errors of the actin cytoskeleton affecting immunity: way beyond WAS and WIP', Immunology and Cell Biology, vol. 97, pp. 389 - 402, http://dx.doi.org/10.1111/imcb.12243
2019
Klinken EM; Gray PE; Pillay B; Worley L; Edwards ESJ; Payne K; Bennetts B; Hung D; Wood BA; Chan JJ; Marshall GM; Mitchell R; Uzel G; Ma CS; Tangye SG; McLean-Tooke A, 2019, 'Diversity of XMEN Disease: Description of 2 Novel Variants and Analysis of the Lymphocyte Phenotype', Journal of Clinical Immunology, http://dx.doi.org/10.1007/s10875-019-00732-2
2019
Norman M; Wainstein B; Anazodo A; Turner A; Ma C; Payne K; Tangye SG; Gray P, 2018, 'Combined Immunodeficiency with Ring Chromosome 21', Journal of Clinical Immunology, vol. 38, pp. 251 - 256, http://dx.doi.org/10.1007/s10875-018-0493-z
2018
Avery DT; Kane A; Nguyen T; Lau A; Nguyen A; Lenthall H; Payne K; Shi W; Brigden H; French E; Bier J; Hermes JR; Zahra D; Sewell WA; Butt D; Elliott M; Boztug K; Meyts I; Choo S; Hsu P; Wong M; Berglund LJ; Gray P; O’Sullivan M; Cole T; Holland SM; Ma CS; Burkhart C; Corcoran LM; Phan TG; Brink R; Uzel G; Deenick EK; Tangye SG, 2018, 'Germline-activating mutations in PIK3CD compromise B cell development and function', Journal of Experimental Medicine, vol. 215, pp. 2073 - 2095, http://dx.doi.org/10.1084/jem.20180010
2018
Alshekaili J; Chand R; Lee CE; Corley S; Kwong K; Papa I; Fulcher DA; Randall KL; Leiding JW; Ma CS; Wilkins MR; Uzel G; Goodnow CC; Vinuesa CG; Tangye SG; Cook MC, 2018, 'STAT3 regulates cytotoxicity of human CD57+ CD4+ T cells in blood and lymphoid follicles', Scientific Reports, vol. 8, http://dx.doi.org/10.1038/s41598-018-21389-8
2018
Moran I; Nguyen A; Khoo WH; Butt D; Bourne K; Young C; Hermes JR; Biro M; Gracie G; Ma CS; Munier CML; Luciani F; Zaunders J; Parker A; Kelleher AD; Tangye SG; Croucher PI; Brink R; Read MN; Phan TG, 2018, 'Memory B cells are reactivated in subcapsular proliferative foci of lymph nodes', Nature Communications, vol. 9, http://dx.doi.org/10.1038/s41467-018-05772-7
2018
Tangye SG, 2018, 'Is it dead or alive? TLR8 can tell news-and-views', Nature Immunology, vol. 19, pp. 324 - 326, http://dx.doi.org/10.1038/s41590-018-0070-x
2018
Koutsakos M; Wheatley AK; Loh L; Clemens EB; Sant S; Nüssing S; Fox A; Chung AW; Laurie KL; Hurt AC; Rockman S; Lappas M; Loudovaris T; Mannering SI; Westall GP; Elliot M; Tangye SG; Wakim LM; Kent SJ; Nguyen THO; Kedzierska K, 2018, 'Circulating TFH cells, serological memory, and tissue compartmentalization shape human influenza-specific B cell immunity', Science Translational Medicine, vol. 10, http://dx.doi.org/10.1126/scitranslmed.aan8405
2018
Guérin A; Kerner G; Marr N; Markle JG; Fenollar F; Wong N; Boughorbel S; Avery DT; Ma CS; Bougarn S; Bouaziz M; Béziat V; Della Mina E; Oleaga-Quintas C; Lazarov T; Worley L; Nguyen T; Patin E; Deswarte C; Martinez-Barricarte R; Boucherit S; Ayral X; Edouard S; Boisson-Dupuis S; Rattina V; Bigio B; Vogt G; Geissmann F; Quintana-Murci L; Chaussabel D; Tangye SG; Raoult D; Abel L; Bustamante J; Casanova JL, 2018, 'IRF4 haploinsufficiency in a family with Whipple's disease', eLife, vol. 7, http://dx.doi.org/10.7554/eLife.32340
2018
Jiménez-Reinoso A; Marin AV; Subias M; López-Lera A; Román-Ortiz E; Payne K; Ma CS; Arbore G; Kolev M; Freeley SJ; Kemper C; Tangye SG; Fernández-Malavé E; Rodríguez de Córdoba S; López-Trascasa M; Regueiro JR, 2018, 'Human plasma C3 is essential for the development of memory B, but not T, lymphocytes', Journal of Allergy and Clinical Immunology, vol. 141, pp. 1151 - 1154.e14, http://dx.doi.org/10.1016/j.jaci.2017.09.037
2018
Bousfiha A; Jeddane L; Picard C; Ailal F; Bobby Gaspar H; Al-Herz W; Chatila T; Crow YJ; Cunningham-Rundles C; Etzioni A; Franco JL; Holland SM; Klein C; Morio T; Ochs HD; Oksenhendler E; Puck J; Tang MLK; Tangye SG; Torgerson TR; Casanova JL; Sullivan KE, 2018, 'The 2017 IUIS Phenotypic Classification for Primary Immunodeficiencies', Journal of Clinical Immunology, vol. 38, pp. 129 - 143, http://dx.doi.org/10.1007/s10875-017-0465-8
2018
Picard C; Bobby Gaspar H; Al-Herz W; Bousfiha A; Casanova JL; Chatila T; Crow YJ; Cunningham-Rundles C; Etzioni A; Franco JL; Holland SM; Klein C; Morio T; Ochs HD; Oksenhendler E; Puck J; Tang MLK; Tangye SG; Torgerson TR; Sullivan KE, 2018, 'International Union of Immunological Societies: 2017 Primary Immunodeficiency Diseases Committee Report on Inborn Errors of Immunity', Journal of Clinical Immunology, vol. 38, pp. 96 - 128, http://dx.doi.org/10.1007/s10875-017-0464-9
2018
Pfajfer L; Mair NK; Jiménez-Heredia R; Genel F; Gulez N; Ardeniz Ö; Hoeger B; Bal SK; Madritsch C; Kalinichenko A; Chandra Ardy R; Gerçeker B; Rey-Barroso J; Ijspeert H; Tangye SG; Simonitsch-Klupp I; Huppa JB; van der Burg M; Dupré L; Boztug K, 2018, 'Mutations affecting the actin regulator WD repeat–containing protein 1 lead to aberrant lymphoid immunity', Journal of Allergy and Clinical Immunology, vol. 142, pp. 1589 - 1604.e11, http://dx.doi.org/10.1016/j.jaci.2018.04.023
2018
Boisson-Dupuis S; Ramirez-Alejo N; Li Z; Patin E; Rao G; Kerner G; Lim CK; Krementsov DN; Hernandez N; Ma CS; Zhang Q; Markle J; Martinez-Barricarte R; Payne K; Fisch R; Deswarte C; Halpern J; Bouaziz M; Mulwa J; Sivanesan D; Lazarov T; Naves R; Garcia P; Itan Y; Boisson B; Checchi A; Jabot-Hanin F; Cobat A; Guennoun A; Jackson CC; Pekcan S; Caliskaner Z; Inostroza J; Costa-Carvalho BT; Tavares de Albuquerque JA; Garcia-Ortiz H; Orozco L; Ozcelik T; Abid A; Rhorfi IA; Souhi H; Amrani HN; Zegmout A; Geissmann F; Michnick SW; Muller-Fleckenstein I; Fleckenstein B; Puel A; Ciancanelli MJ; Marr N; Abolhassani H; Balcells ME; Condino-Neto A; Strickler A; Abarca K; Teuscher C; Ochs HD; Reisli I; Sayar EH; El-Baghdadi J; Bustamante J; Hammarström L; Tangye SG; Pellegrini S; Quintana-Murci L; Abel L; Casanova JL, 2018, 'Tuberculosis and impaired IL-23–dependent IFN- immunity in humans homozygous for a common TYK2 missense variant', Science Immunology, vol. 3, http://dx.doi.org/10.1126/sciimmunol.aau8714
2018
Kong XF; Martinez-Barricarte R; Kennedy J; Mele F; Lazarov T; Deenick EK; Ma CS; Breton G; Lucero KB; Langlais D; Bousfiha A; Aytekin C; Markle J; Trouillet C; Jabot-Hanin F; Arlehamn CSL; Rao G; Picard C; Lasseau T; Latorre D; Hambleton S; Deswarte C; Itan Y; Abarca K; Moraes-Vasconcelos D; Ailal F; Ikinciogullari A; Dogu F; Benhsaien I; Sette A; Abel L; Boisson-Dupuis S; Schröder B; Nussenzweig MC; Liu K; Geissmann F; Tangye SG; Gros P; Sallusto F; Bustamante J; Casanova JL, 2018, 'Disruption of an antimycobacterial circuit between dendritic and helper T cells in human SPPL2a deficiency', Nature Immunology, vol. 19, pp. 973 - 985, http://dx.doi.org/10.1038/s41590-018-0178-z
2018
Bucciol G; Moens L; Payne K; Wollants E; Mekahli D; Levtchenko E; Vermeulen F; Tousseyn T; Gray P; Ma CS; Tangye SG; Van Ranst M; Brown JR; Breuer J; Meyts I, 2018, 'Chronic Aichi Virus Infection in a Patient with X-Linked Agammaglobulinemia', Journal of Clinical Immunology, vol. 38, pp. 748 - 752, http://dx.doi.org/10.1007/s10875-018-0558-z
2018
Béziat V; Li J; Lin JX; Ma CS; Li P; Bousfiha A; Pellier I; Zoghi S; Baris S; Keles S; Gray P; Du N; Wang Y; Zerbib Y; Lévy R; Leclercq T; About F; Lim AI; Rao G; Payne K; Pelham SJ; Avery DT; Deenick EK; Pillay B; Chou J; Guery R; Belkadi A; Guérin A; Migaud M; Rattina V; Ailal F; Benhsaien I; Bouaziz M; Habib T; Chaussabel D; Marr N; El-Benna J; Grimbacher B; Wargon O; Bustamante J; Boisson B; Müller-Fleckenstein I; Fleckenstein B; Chandesris MO; Titeux M; Fraitag S; Alyanakian MA; Leruez-Ville M; Picard C; Meyts I; Di Santo JP; Hovnanian A; Somer A; Ozen A; Rezaei N; Chatila TA; Abel L; Leonard WJ; Tangye SG; Puel A; Casanova JL, 2018, 'A recessive form of hyper-IgE syndrome by disruption of ZNF341-dependent STAT3 transcription and activity', Science Immunology, vol. 3, http://dx.doi.org/10.1126/sciimmunol.aat4956
2018
Bucciol G; Moens L; Payne K; Wollants E; Mekahli D; Levtchenko E; Vermeulen F; Tousseyn T; Gray P; Ma CS; Tangye SG; Van Ranst M; Brown JR; Breuer J; Meyts I, 2018, 'Correction to: Chronic Aichi Virus Infection in a Patient with X-Linked Agammaglobulinemia (Journal of Clinical Immunology, (2018), 38, 7, (748-752), 10.1007/s10875-018-0558-z)', Journal of Clinical Immunology, vol. 38, pp. 938 - 939, http://dx.doi.org/10.1007/s10875-018-0570-3
2018
Martínez-Barricarte R; Markle JG; Ma CS; Deenick EK; Ramírez-Alejo N; Mele F; Latorre D; Mahdaviani SA; Aytekin C; Mansouri D; Bryant VL; Jabot-Hanin F; Deswarte C; Nieto-Patlán A; Surace L; Kerner G; Itan Y; Jovic S; Avery DT; Wong N; Rao G; Patin E; Okada S; Bigio B; Boisson B; Rapaport F; Seeleuthner Y; Schmidt M; Ikinciogullari A; Dogu F; Tanir G; Tabarsi P; Bloursaz MR; Joseph JK; Heer A; Kong XF; Migaud M; Lazarov T; Geissmann F; Fleckenstein B; Arlehamn CL; Sette A; Puel A; Emile JF; van de Vosse E; Quintana-Murci L; Di Santo JP; Abel L; Boisson-Dupuis S; Bustamante J; Tangye SG; Sallusto F; Casanova JL, 2018, 'Human IFN- immunity to mycobacteria is governed by both IL-12 and IL-23', Science Immunology, vol. 3, http://dx.doi.org/10.1126/sciimmunol.aau6759
2018
Deenick EK; Morey A; Danta M; Emmett L; Fay K; Gracie G; Ma CS; Macintosh R; Smith SABC; Sasson SC; Sewell WA; Cowley M; Tangye SG; Kelleher AD; Phan TG, 2018, 'Reversible Suppression of Lymphoproliferation and Thrombocytopenia with Rapamycin in a Patient with Common Variable Immunodeficiency', Journal of Clinical Immunology, vol. 38, pp. 159 - 162, http://dx.doi.org/10.1007/s10875-018-0477-z
2018
Phan TG; Tangye SG, 2018, 'B cells race the clock to get a second wind', Nature Immunology, vol. 19, pp. 791 - 793, http://dx.doi.org/10.1038/s41590-018-0166-3
2018
Tangye SG; Palendira U; Edwards ESJ, 2017, 'Human immunity against EBV-lessons from the clinic', Journal of Experimental Medicine, vol. 214, pp. 269 - 283, http://dx.doi.org/10.1084/jem.20161846
2017
Abolhassani H; Edwards ESJ; Ikinciogullari A; Jing H; Borte S; Buggert M; Du L; Matsuda-Lennikov M; Romano R; Caridha R; Bade S; Zhang Y; Frederiksen J; Fang M; Bal SK; Haskologlu S; Dogu F; Tacyildiz N; Matthews HF; McElwee JJ; Gostick E; Price DA; Palendira U; Aghamohammadi A; Boisson B; Rezaei N; Karlsson AC; Lenardo MJ; Casanova JL; Hammarström L; Tangye SG; Su HC; Pan-Hammarström Q, 2017, 'Combined immunodeficiency and Epstein-Barr virus- induced B cell malignancy in humans with inherited CD70 deficiency', Journal of Experimental Medicine, vol. 214, pp. 91 - 106, http://dx.doi.org/10.1084/jem.20160849
2017
Moens L; Schaballie H; Bosch B; Voet A; Bossuyt X; Casanova JL; Boisson-Dupuis S; Tangye SG; Meyts I, 2017, 'AD Hyper-IgE Syndrome Due to a Novel Loss-of-Function Mutation in STAT3: a Diagnostic Pursuit Won by Clinical Acuity', Journal of Clinical Immunology, vol. 37, pp. 12 - 17, http://dx.doi.org/10.1007/s10875-016-0351-9
2017
Deenick EK; Tangye SG, 2017, 'The TORC that Gets the GC Cycling', Immunity, vol. 46, pp. 974 - 976, http://dx.doi.org/10.1016/j.immuni.2017.06.003
2017
Tangye SG; Pillay B; Randall KL; Avery DT; Tri GP; Gray P; Ziegler JB; Smart JM; Peake J; Arkwright PD; Hambleton S; Orange J; Goodnow CC; Uzel G; Casanova J-L; Lugo Reyes SO; Freeman AF; Su HC; Ma CS, 2017, 'Dedicator of cytokinesis 8-deficient CD4(+) T cells are biased to a T(H)2 effector fate at the expense of T(H)1 and T(H)17 cells', JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, vol. 139, pp. 933 - 949, http://dx.doi.org/10.1016/j.jaci.2016.07.016
2017
Infantino S; Light A; O'donnell K; Bryant V; Avery DT; Elliott M; Tangye SG; Belz G; Mackay F; Richard S; Tarlinton D, 2017, 'Arginine methylation catalyzed by PRMT1 is required for B cell activation and differentiation', Nature Communications, vol. 8, http://dx.doi.org/10.1038/s41467-017-01009-1
2017
Tangye SG; Pelham SJ; Deenick EK; Ma CS, 2017, 'Cytokine-mediated regulation of human lymphocyte development and function: Insights from primary immunodeficiencies', Journal of Immunology, vol. 199, pp. 1949 - 1958, http://dx.doi.org/10.4049/jimmunol.1700842
2017
Phan TG; Tangye SG, 2017, 'Memory B cells: total recall', Current Opinion in Immunology, vol. 45, pp. 132 - 140, http://dx.doi.org/10.1016/j.coi.2017.03.005
2017
Suan D; Kräutler NJ; Maag JLV; Butt D; Bourne K; Hermes JR; Avery DT; Young C; Statham A; Elliott M; Dinger ME; Basten A; Tangye SG; Brink R, 2017, 'CCR6 Defines Memory B Cell Precursors in Mouse and Human Germinal Centers, Revealing Light-Zone Location and Predominant Low Antigen Affinity', Immunity, vol. 47, pp. 1142 - 1153.e4, http://dx.doi.org/10.1016/j.immuni.2017.11.022
2017
Tangye SG; Pillay B; Randall KL; Avery DT; Phan TG; Gray P; Ziegler JB; Smart JM; Peake J; Arkwright PD; Hambleton S; Orange J; Goodnow CC; Uzel G; Casanova JL; Lugo Reyes SO; Freeman AF; Su HC; Ma CS, 2017, 'Dedicator of cytokinesis 8–deficient CD4+ T cells are biased to a TH2 effector fate at the expense of TH1 and TH17 cells', Journal of Allergy and Clinical Immunology, vol. 139, pp. 933 - 949, http://dx.doi.org/10.1016/j.jaci.2016.07.016
2017
Kearney CJ; Vervoort SJ; Ramsbottom KM; Freeman AJ; Michie J; Peake J; Casanova JL; Picard C; Tangye SG; Ma CS; Johnstone RW; Randall KL; Oliaro J, 2017, 'DOCK8 drives Src-dependent NK Cell effector function', Journal of Immunology, vol. 199, pp. 2118 - 2127, http://dx.doi.org/10.4049/jimmunol.1700751
2017
Tangye SG; Forbes LR; Leiding J; Preece K; Kumar AR; Gambineri E; Milner JD; Cooper MA; Seppänen M, 2017, 'Low IgE is insufficiently sensitive to guide genetic testing of STAT3 gain-of-function mutations', Clinical Chemistry, vol. 63, pp. 1539 - 1540, http://dx.doi.org/10.1373/clinchem.2017.273458
2017
Munoz MA; Jurczyluk J; Mehr S; Chai RC; Arts RJW; Sheu A; McMahon C; Center JR; Singh-Grewal D; Chaitow J; Campbell DE; Quinn JMW; Alexandrov K; Tnimov Z; Tangye SG; Simon A; Phan TG; Rogers MJ, 2017, 'Defective protein prenylation is a diagnostic biomarker of mevalonate kinase deficiency', Journal of Allergy and Clinical Immunology, vol. 140, pp. 873 - 875.e6, http://dx.doi.org/10.1016/j.jaci.2017.02.033
2017
Tangye SG, 2017, 'Pathogenic CD4 + T cells regulating B-cell differentiation in autoimmunity: Not exactly Tfh cells', Immunology and Cell Biology, vol. 95, pp. 419 - 421, http://dx.doi.org/10.1038/icb.2017.20
2017
Cottineau J; Kottemann MC; Lach FP; Kang YH; Vély F; Deenick EK; Lazarov T; Gineau L; Wang Y; Farina A; Chansel M; Lorenzo L; Piperoglou C; Ma CS; Nitschke P; Belkadi A; Itan Y; Boisson B; Jabot-Hanin F; Picard C; Bustamante J; Eidenschenk C; Boucherit S; Aladjidi N; Lacombe D; Barat P; Qasim W; Hurst JA; Pollard AJ; Uhlig HH; Fieschi C; Michon J; Bermudez VP; Abel L; De Villartay JP; Geissmann F; Tangye SG; Hurwitz J; Vivier E; Casanova JL; Smogorzewska A; Jouanguy E, 2017, 'Inherited GINS1 deficiency underlies growth retardation along with neutropenia and NK cell deficiency', Journal of Clinical Investigation, vol. 127, pp. 1991 - 2006, http://dx.doi.org/10.1172/JCI90727
2017
Woon HG; Braun A; Li J; Smith C; Edwards J; Sierro F; Feng CG; Khanna R; Elliot M; Bell A; Hislop AD; Tangye SG; Rickinson AB; Gebhardt T; Britton WJ; Palendira U, 2016, 'Compartmentalization of Total and Virus-Specific Tissue-Resident Memory CD8+ T Cells in Human Lymphoid Organs', PLoS Pathogens, vol. 12, http://dx.doi.org/10.1371/journal.ppat.1005799
2016
Pelham SJ; Lenthall HC; Deenick EK; Tangye SG, 2016, 'Elucidating the effects of disease-causing mutations on STAT3 function in autosomal-dominant hyper-IgE syndrome', Journal of Allergy and Clinical Immunology, vol. 138, pp. 1210 - 1213.e5, http://dx.doi.org/10.1016/j.jaci.2016.04.020
2016
Meli AP; Fontés G; Avery DT; Leddon SA; Tam M; Elliot M; Ballesteros-Tato A; Miller J; Stevenson MM; Fowell DJ; Tangye SG; King IL, 2016, 'The Integrin LFA-1 Controls T Follicular Helper Cell Generation and Maintenance', Immunity, vol. 45, pp. 831 - 846, http://dx.doi.org/10.1016/j.immuni.2016.09.018
2016
vijayan D; redzwan M; avery DT; wirasinha RC; brink R; walters G; adelstein S; kobayashi M; gray P; elliott M; king C; vinuesa C; ghilardi N; ma CS; Tangye SG; batten M, 2016, 'IL-27 Directly Enhances Germinal Center B Cell Activity and Potentiates Lupus in Sanroque Mice', Journal of Immunology, vol. 197, pp. 3008 - 3017, http://dx.doi.org/10.4049/jimmunol.1600652
2016
Moens L; Kane A; Tangye SG, 2016, 'Naïve and memory B cells exhibit distinct biochemical responses following BCR engagement', Immunology and Cell Biology, vol. 94, pp. 774 - 786, http://dx.doi.org/10.1038/icb.2016.41
2016
Ma CS; Tangye SG, 2016, 'Cytotoxic T cells that escape exhaustion', NATURE, vol. 537, pp. 312 - 314, http://dx.doi.org/10.1038/nature19428
2016
Ma CS, 2016, 'Human T Follicular Helper Cells in Primary Immunodeficiency: Quality Just as Important as Quantity', Journal of Clinical Immunology, vol. 36, pp. 40 - 47, http://dx.doi.org/10.1007/s10875-016-0257-6
2016
Jurczyluk J; Munoz MA; Skinner OP; Chai RC; Ali N; Palendira U; Quinn JMW; Preston A; Tangye SG; Brown AJ; Argent E; Ziegler JB; Mehr S; Rogers MJ, 2016, 'Mevalonate kinase deficiency leads to decreased prenylation of Rab GTPases', Immunology and Cell Biology, vol. 94, pp. 994 - 999, http://dx.doi.org/10.1038/icb.2016.58
2016
Ma CS; Wong N; Rao G; Nguyen A; Avery DT; Payne K; Torpy J; O'Young P; Deenick E; Bustamante J; Puel A; Okada S; Kobayashi M; Martinez-Barricarte R; Elliott M; Kilic SS; Baghdadi JE; Minegishi Y; Bousfiha A; Robertson N; Hambleton S; Arkwright PD; French M; Blincoe AK; Hsu P; Campbell DE; Stormon MO; Wong M; Adelstein S; Fulcher DA; Cook MC; Stepensky P; Boztug K; Beier R; Ikincioğullari A; Ziegler JB; Gray P; Picard C; Boisson-Dupuis S; Phan TG; Grimbacher B; Warnatz K; Holland SM; Uzel G; Casanova JL; Tangye SG, 2016, 'Unique and shared signaling pathways cooperate to regulate the differentiation of human CD4+ T cells into distinct effector subsets', Journal of Experimental Medicine, vol. 213, pp. 1589 - 1608, http://dx.doi.org/10.1084/jem.20151467
2016
Jurczyluk J; Munoz MA; Skinner OP; Chai RC; Ali N; Palendira U; Quinn JMW; Preston A; Tangye SG; Brown AJ; Argent E; Ziegler JB; Mehr S; Rogers MJ, 2016, 'Mevalonate kinase deficiency leads to decreased prenylation of Rab GTPases', IMMUNOLOGY AND CELL BIOLOGY, vol. 94, pp. 994 - 999, http://dx.doi.org/10.1038/icb.2016.58
2016
Kane A; Lau A; Brink R; Tangye SG; Deenick EK, 2016, 'B-cell–specific STAT3 deficiency: Insight into the molecular basis of autosomal-dominant hyper-IgE syndrome', Journal of Allergy and Clinical Immunology, vol. 138, pp. 1455 - 1458.e3, http://dx.doi.org/10.1016/j.jaci.2016.05.018
2016
Wang Y; Ma CS; Ling Y; Bousfiha A; Camcioglu Y; Jacquot S; Payne K; Crestani E; Roncagalli R; Belkadi A; Kerner G; Lorenzo L; Deswarte C; Chrabieh M; Patin E; Vincent QB; Müller-Fleckenstein I; Fleckenstein B; Ailal F; Quintana-Murci L; Fraitag S; Alyanakian MA; Leruez-Ville M; Picard C; Puel A; Bustamante J; Boisson-Dupuis S; Malissen M; Malissen B; Abel L; Hovnanian A; Notarangelo LD; Jouanguy E; Tangye SG; Béziat V; Casanova JL, 2016, 'Dual T cell- and B cell-intrinsic deficiency in humans with biallelic RLT PR mutations', Journal of Experimental Medicine, vol. 213, pp. 2413 - 2435, http://dx.doi.org/10.1084/jem.20160576
2016
Tangye SG, 2015, 'Advances in IL-21 biology-enhancing our understanding of human disease', Current Opinion in Immunology, vol. 34, pp. 107 - 115, http://dx.doi.org/10.1016/j.coi.2015.02.010
2015
Wilson RP; Ives ML; Rao G; Lau A; Payne K; Kobayashi M; Arkwright PD; Peake J; Wong M; Adelstein S; Smart JM; French MA; Fulcher DA; Picard C; Bustamante J; Boisson-Dupuis S; Gray P; Stepensky P; Warnatz K; Freeman AF; Rossjohn J; McCluskey J; Holland SM; Casanova JL; Uzel G; Ma CS; Tangye SG; Deenick EK, 2015, 'STAT3 is a critical cell-intrinsic regulator of human unconventional T cell numbers and function', Journal of Experimental Medicine, vol. 212, pp. 855 - 864, http://dx.doi.org/10.1084/jem.20141992
2015
Butt D; Chan TD; Bourne K; Hermes JR; Nguyen A; Statham A; O'Reilly LA; Strasser A; Price S; Schofield P; Christ D; Basten A; Ma CS; Tangye SG; Phan TG; Rao VK; Brink R, 2015, 'FAS Inactivation Releases Unconventional Germinal Center B Cells that Escape Antigen Control and Drive IgE and Autoantibody Production', Immunity, vol. 42, pp. 890 - 902, http://dx.doi.org/10.1016/j.immuni.2015.04.010
2015
Suan D; Nguyen A; Moran I; Bourne K; Hermes JR; Arshi M; Hampton HR; Tomura M; Miwa Y; Kelleher AD; Kaplan W; Deenick EK; Tangye SG; Brink R; Chtanova T; Phan TG, 2015, 'T Follicular Helper Cells Have Distinct Modes of Migration and Molecular Signatures in Naive and Memory Immune Responses', Immunity, vol. 42, pp. 704 - 718, http://dx.doi.org/10.1016/j.immuni.2015.03.002
2015
Tangye SG; Brink R; Goodnow CC; Phan TG, 2015, 'SnapShot: Interactions between B Cells and T Cells', Cell, vol. 162, pp. 926 - 926.e1, http://dx.doi.org/10.1016/j.cell.2015.07.055
2015
Gray PE; O’Brien TA; Wagle M; Tangye SG; Palendira U; Roscioli T; Choo S; Sutton R; Ziegler JB; Frith K, 2015, 'Cerebral Vasculitis in X-linked Lymphoproliferative Disease Cured by Matched Unrelated Cord Blood Transplant', Journal of Clinical Immunology, vol. 35, pp. 604 - 609, http://dx.doi.org/10.1007/s10875-015-0194-9
2015
Ma CS; Wong N; Rao G; Avery DT; Torpy J; Hambridge T; Bustamante J; Okada S; Stoddard JL; Deenick EK; Pelham SJ; Payne K; Boisson-Dupuis S; Puel A; Kobayashi M; Arkwright PD; Kilic SS; El Baghdadi J; Nonoyama S; Minegishi Y; Mahdaviani SA; Mansouri D; Bousfiha A; Blincoe AK; French MA; Hsu P; Campbell DE; Stormon MO; Wong M; Adelstein S; Smart JM; Fulcher DA; Cook MC; Phan TG; Stepensky P; Boztug K; Kansu A; Ikincioʇullari A; Baumann U; Beier R; Roscioli T; Ziegler JB; Gray P; Picard C; Grimbacher B; Warnatz K; Holland SM; Casanova JL; Uzel G; Tangye SG, 2015, 'Monogenic mutations differentially affect the quantity and quality of T follicular helper cells in patients with human primary immunodeficiencies', Journal of Allergy and Clinical Immunology, vol. 136, pp. 993 - 1006.e1, http://dx.doi.org/10.1016/j.jaci.2015.05.036
2015
Tangye SG, 2015, 'Thucydides and longer-lived plasma cells', Blood, vol. 125, pp. 1684 - 1685, http://dx.doi.org/10.1182/blood-2015-01-622514
2015
Okada S; Markle JG; Deenick EK; Mele F; Averbuch D; Lagos M; Alzahrani M; Al-Muhsen S; Halwani R; Ma CS; Wong N; Soudais C; Henderson LA; Marzouqa H; Shamma J; Gonzalez M; Martinez-Barricarte R; Okada C; Avery DT; Latorre D; Deswarte C; Jabot-Hanin F; Torrado E; Fountain J; Belkadi A; Itan Y; Boisson B; Migaud M; Lindestam Arlehamn CS; Sette A; Breton S; Cluskey J; Rossjohn J; De Villartay JP; Moshous D; Hambleton S; Latour S; Arkwright PD; Picard C; Lantz O; Engelhard D; Kobayashi M; Abel L; Cooper AM; Notarangelo LD; Boisson-Dupuis S; Puel A; Sallusto F; Bustamante J; Tangye SG; Casanova JL, 2015, 'Impairment of immunity to Candida and Mycobacterium in humans with bi-allelic RORC mutations', Science, vol. 349, pp. 606 - 613, http://dx.doi.org/10.1126/science.aaa4282
2015
Kreins AY; Ciancanelli MJ; Okada S; Kong XF; Ramírez-Alejo N; Kilic SS; El Baghdadi J; Nonoyama S; Mahdaviani SA; Ailal F; Bousfiha A; Mansouri D; Nievas E; Ma CS; Rao G; Bernasconi A; Kuehn HS; Niemela J; Stoddard J; Deveau P; Cobat A; Azbaoui SE; Sabri A; Lim CK; Sundin M; Avery DT; Halwani R; Grant AV; Boisson B; Bogunovic D; Itan Y; Moncada-Velez M; Martinez-Barricarte R; Migaud M; Deswarte C; Alsina L; Kotlarz D; Klein C; Muller-Fleckenstein I; Fleckenstein B; Cormier-Daire V; Rose-John S; Picard C; Hammarstrom L; Puel A; Al-Muhsen S; Abel L; Chaussabel D; Rosenzweig SD; Minegishi Y; Tangye SG; Bustamante J; Casanova JL; Boisson-Dupuis S, 2015, 'Human TYK2 deficiency: Mycobacterial and viral infections without hyper-IgE syndrome', Journal of Experimental Medicine, vol. 212, pp. 1641 - 1662, http://dx.doi.org/10.1084/jem.20140280
2015
Kane A; Deenick EK; Ma CS; Cook MC; Uzel G; Tangye SG, 2014, 'STAT3 is a central regulator of lymphocyte differentiation and function', Current Opinion in Immunology, vol. 28, pp. 49 - 57, http://dx.doi.org/10.1016/j.coi.2014.01.015
2014
Tangye SG, 2014, 'XLP: Clinical Features and Molecular Etiology due to Mutations in SH2D1A Encoding SAP', Journal of Clinical Immunology, vol. 34, pp. 772 - 779, http://dx.doi.org/10.1007/s10875-014-0083-7
2014
Tangye SG, 2014, 'T cells require DOCK8 for flexibility and function', Journal of Experimental Medicine, vol. 211, pp. 2482 - 2483, http://dx.doi.org/10.1084/jem.21113insight2
2014
Moens L; Tangye SG, 2014, 'Cytokine-mediated regulation of plasma cell generation: IL-21 takes center stage', Frontiers in Immunology, vol. 5, http://dx.doi.org/10.3389/fimmu.2014.00065
2014
Lucas CL; Kuehn HS; Zhao F; Niemela JE; Deenick EK; Palendira U; Avery DT; Moens L; Cannons JL; Biancalana M; Stoddard J; Ouyang W; Frucht DM; Rao VK; Atkinson TP; Agharahimi A; Hussey AA; Folio LR; Olivier KN; Fleisher TA; Pittaluga S; Holland SM; Cohen JI; Oliveira JB; Tangye SG; Schwartzberg PL; Lenardo MJ; Uzel G, 2014, 'Dominant-activating germline mutations in the gene encoding the PI(3)K catalytic subunit p110δ result in T cell senescence and human immunodeficiency', Nature Immunology, vol. 15, pp. 88 - 97, http://dx.doi.org/10.1038/ni.2771
2014
Hutchinson AT; Jones DR; McCauley Winter P; Tangye SG; Raison RL, 2014, 'Cell membrane associated free kappa light chains are found on a subset of tonsil and in vitro-derived plasmablasts', Human Immunology, http://dx.doi.org/10.1016/j.humimm.2014.08.196
2014
Ma CS; Uzel G; Tangye SG, 2014, 'Human T follicular helper cells in primary immunodeficiencies', Current Opinion in Pediatrics, vol. 26, pp. 720 - 726, http://dx.doi.org/10.1097/MOP.0000000000000157
2014
Menard L; Cantaert T; Chamberlain N; Tangye SG; Riminton S; Church JA; Klion A; Cunningham-Rundles C; Nichols KE; Meffre E, 2014, 'Signaling lymphocytic activation molecule (SLAM)/SLAM-associated protein pathway regulates human B-cell tolerance', Journal of Allergy and Clinical Immunology, vol. 133, pp. 1149 - 1161, http://dx.doi.org/10.1016/j.jaci.2013.10.051
2014
Koganti S; Hui-Yuen J; McAllister S; Gardner B; Grasser F; Palendira U; Tangye SG; Freeman AF; Bhaduri-McIntosh S, 2014, 'STAT3 interrupts ATR-Chk1 signaling to allow oncovirus-mediated cell proliferation', Proceedings of the National Academy of Sciences of the United States of America, vol. 111, pp. 4946 - 4951, http://dx.doi.org/10.1073/pnas.1400683111
2014
Tangye SG, 2014, 'The right ''Job'' for STAT3 mutant mice!', Blood, vol. 123, pp. 2907 - 2909, http://dx.doi.org/10.1182/blood-2014-04-563726
2014
Kuehn HS; Ouyang W; Lo B; Deenick EK; Niemela JE; Avery DT; Schickel JN; Tran DQ; Stoddard J; Zhang Y; Frucht DM; Dumitriu B; Scheinberg P; Folio LR; Frein CA; Price S; Koh C; Heller T; Seroogy CM; Huttenlocher A; Rao VK; Su HC; Kleiner D; Notarangelo LD; Rampertaap Y; Olivier KN; McElwee J; Hughes J; Pittaluga S; Oliveira JB; Meffre E; Fleisher TA; Holland SM; Lenardo MJ; Tangye SG; Uzel G, 2014, 'Immune dysregulation in human subjects with heterozygous germline mutations in CTLA4', Science, vol. 345, pp. 1623 - 1627, http://dx.doi.org/10.1126/science.1255904
2014
Tangye SG, 2014, 'XLP: Clinical Features and Molecular Etiology due to Mutations in SH2D1A Encoding SAP', Journal of Clinical Immunology, http://dx.doi.org/10.1007/s10875-014-0083-7
2014
Reynaud CA; Tangye S, 2014, 'Editorial overview: Lymphocyte activation and effector functions.', Current opinion in immunology, vol. 28
2014
Reynaud CA; Tangye S, 2014, 'Editorial overview: Lymphocyte activation and effector functions.', Current opinion in immunology, vol. 28
2014
Hutchinson AT; Jones DR; McCauley Winter P; Tangye SG; Raison RL, 2014, 'Cell membrane associated free kappa light chains are found on a subset of tonsil and in vitro-derived plasmablasts', Human Immunology, vol. 75, pp. 986 - 990, http://dx.doi.org/10.1016/j.humimm.2014.08.196
2014
He J; Tsai LM; Leong YA; Hu X; Ma CS; Chevalier N; Sun X; Vandenberg K; Rockman S; Ding Y; Zhu L; Wei W; Wang C; Karnowski A; Belz GT; Ghali JR; Cook MC; Riminton DS; Veillette A; Schwartzberg PL; Mackay F; Brink R; Tangye SG; Vinuesa CG; Mackay CR; Li Z; Yu D, 2013, 'Circulating precursor CCR7loPD-1hi CXCR5+ CD4+ T cells indicate tfh cell activity and promote antibody responses upon antigen reexposure', Immunity, vol. 39, pp. 770 - 781, http://dx.doi.org/10.1016/j.immuni.2013.09.007
2013
Tangye SG; Ma CS; Brink R; Deenick EK, 2013, 'The good, the bad and the ugly-T FH cells in human health and disease', Nature Reviews Immunology, vol. 13, pp. 412 - 426, http://dx.doi.org/10.1038/nri3447
2013
Ives ML; Ma CS; Palendira U; Chan A; Bustamante J; Boisson-Dupuis S; Arkwright PD; Engelhard D; Averbuch D; Magdorf K; Roesler J; Peake J; Wong M; Adelstein S; Choo S; Smart JM; French MA; Fulcher DA; Cook MC; Picard C; Durandy A; Tsumura M; Kobayashi M; Uzel G; Casanova JL; Tangye SG; Deenick EK, 2013, 'Signal transducer and activator of transcription 3 (STAT3) mutations underlying autosomal dominant hyper-IgE syndrome impair human CD8+ T-cell memory formation and function', Journal of Allergy and Clinical Immunology, vol. 132, pp. 400 - 411.e9, http://dx.doi.org/10.1016/j.jaci.2013.05.029
2013
Crawford G; Enders A; Gileadi U; Stankovic S; Zhang Q; Lambe T; Crockford TL; Lockstone HE; Freeman A; Arkwright PD; Smart JM; Ma CS; Tangye SG; Goodnow CC; Cerundolo V; Godfrey DI; Su HC; Randall KL; Cornall RJ, 2013, 'DOCK8 is critical for the survival and function of NKT cells', Blood, vol. 122, pp. 2052 - 2061, http://dx.doi.org/10.1182/blood-2013-02-482331
2013
Agrawal S; Smith SABC; Tangye SG; Sewell WA, 2013, 'Transitional B cell subsets in human bone marrow', Clinical and Experimental Immunology, vol. 174, pp. 53 - 59, http://dx.doi.org/10.1111/cei.12149
2013
Deenick EK; Avery DT; Chan A; Berglund LJ; Ives ML; Moens L; Stoddard JL; Bustamante J; Boisson-Dupuis S; Tsumura M; Kobayashi M; Arkwright PD; Averbuch D; Engelhard D; Roesler J; Peake J; Wong M; Adelstein S; Choo S; Smart JM; French MA; Fulcher DA; Cook MC; Picard C; Durandy A; Klein C; Holland SM; Uzel G; Casanova JL; Ma CS; Tangye SG, 2013, 'Naive and memory human B cells have distinct requirements for STAT3 activation to differentiate into antibody-secreting plasma cells', Journal of Experimental Medicine, vol. 210, pp. 2739 - 2753, http://dx.doi.org/10.1084/jem.20130323
2013
Berglund LJ; Avery DT; Ma CS; Moens L; Deenick EK; Bustamante J; Boisson-Dupuis S; Wong M; Adelstein S; Arkwright PD; Bacchetta R; Bezrodnik L; Dadi H; Roifman CM; Fulcher DA; Ziegler JB; Smart JM; Kobayashi M; Picard C; Durandy A; Cook MC; Casanova JL; Uzel G; Tangye SG, 2013, 'IL-21 signalling via STAT3 primes human näive B cells to respond to IL-2 to enhance their differentiation into plasmablasts', Blood, vol. 122, pp. 3940 - 3950, http://dx.doi.org/10.1182/blood-2013-06-506865
2013
Boisson B; Wang YD; Bosompem A; Ma CS; Lim A; Kochetkov T; Tangye SG; Casanova JL; Conley ME, 2013, 'A recurrent dominant negative E47 mutation causes agammaglobulinemia and BCR- B cells', Journal of Clinical Investigation, vol. 123, pp. 4781 - 4785, http://dx.doi.org/10.1172/JCI71927
2013
Tangye SG, 2013, 'To B1 or not to B1: that really is still the question!', Blood, vol. 121, pp. 5109 - 5110, http://dx.doi.org/10.1182/blood-2013-05-500074
2013
Byun M; Ma Cindy S. CS; Akçay A; Pedergnana V; Palendira U; Myoung J; Avery DT; Liu Y; Abhyankar A; Lorenzo L; Schmidt M; Lim HK; Cassar O; Migaud M; Rozenberg F; Canpolat N; Aydogan G; Fleckenstein B; Bustamante J; Picard C; Gessain A; Jouanguy E; Cesarman E; Olivier M; Gros P; Abel L; Croft M; Tangye SG; Casanova JL, 2013, 'Inherited human OX40 deficiency underlying classic kaposi sarcoma of childhood', Journal of Experimental Medicine, vol. 210, pp. 1743 - 1759, http://dx.doi.org/10.1084/jem.20130592
2013
Hill ER; Kogantil S; Zhi J; Megyola C; Freeman AF; Palendira U; Tangye SG; Farrell PJ; Bhaduri-McIntosh S, 2013, 'Signal transducer and activator of transcription 3 limits epstein-barr virus lytic activation in B lymphocytes', Journal of Virology, vol. 87, pp. 11438 - 11446, http://dx.doi.org/10.1128/JVI.01762-13
2013
Cliffe S; Bloch D; Suryani S; Kamsteeg E; Avery D; Palendira U; Church J; Wainstein B; Trizzino A; Lefranc G; Akatcherian C; Megarbane A; Gilissen C; Moshous D; Reichenbach J; Misbah S; Salzer U; Abinun M; Ong P; Stepensky P; Ruga E; Ziegler JB; Wong M; Tangye SG; Lindeman R; Buckley M; Roscioli T, 2012, 'Clinical, molecular, and cellular immunologic findings in patients with SP110-associated veno-occlusive disease with immunodeficiency syndrome', Journal of Allergy and Clinical Immunology, vol. 130, pp. 735 - 742, http://dx.doi.org/10.1016/j.jaci.2012.02.054
2012
Belz G; Tangye SG; Liston A, 2012, 'A new ICB sister journal focuses on clinical and translational immunology', CLINICAL & TRANSLATIONAL IMMUNOLOGY, vol. 1, http://dx.doi.org/10.1038/cti.2012.3
2012
Tangye SG; Brink R, 2012, 'A helping hand from neutrophils in T cell-independent antibody responses?', Nature Immunology, vol. 13, pp. 111 - 113, http://dx.doi.org/10.1038/ni.2214
2012
Ma C; Avery D; Chan A; Batten ML; Bustamante J; Boisson-Dupuis S; Arkwright PD; Kreins AY; Averbuch D; Engelhard D; Magdorf K; Kilic S; Minegishi Y; Gray PE, 2012, 'Functional STAT3 deficiency compromises the generation of human T follicular helper cells', Blood, vol. 119, pp. 3997 - 4008, http://dx.doi.org/10.1182/blood-2011-11-392985
2012
Crequer A; Troeger A; Patino E; Ma CS; Picard C; Pedergnana V; Fieschi C; Lim A; Abhyankar A; Gineau L; Mueller-Fleckenstein I; Schmidt M; Taieb A; Kreuger J; Abela L; Tangye SG; Orth G; Williams DA; Casanova J-L; Jouanguy E, 2012, 'Human RHOH deficiency causes T cell defects and susceptibility to EV-HPV infections', Journal of Clinical Investigation, vol. 122, pp. 3239 - 3247, http://dx.doi.org/10.1172/JCI62949
2012
Ma CS; Deenick EK; Batten ML; Tangye SG, 2012, 'The origins, function, and regulation of T follicular helper cells', Journal of Experimental Medicine, vol. 209, pp. 1241 - 1253, http://dx.doi.org/10.1084/jem.20120994
2012
Palendira U; Bell A; Ma CS; Abbott RJM; Phan TG; Riminton DS; Choo S; Smart J; Lougaris V; Giliani S; Buckley RH; Grimbacher B; Alvaro F; Klion AD; Nichols K; Adelstein S; Rickinson A; Tangye SG, 2012, 'Expansion of somatically reverted memory CD8+ T cells in patients with X-linked lymphoproliferative disease caused by selective pressure from Epstein-Barr virus', Journal of Experimental Medicine, vol. 209, pp. 913 - 924, http://dx.doi.org/10.1084/jem.20112391
2012
Chang PP; Barral P; Fitch J; Pratama A; Ma CS; Kallies A; Hogan JJ; Cerundolo V; Tangye SG; Bittman R; Nutt SL; Brink R; Godfrey DI; Batista FD; Vinuesa C, 2012, 'Identification of Bcl-6-dependent follicular helper NKT cells that provide cognate help for B cell responses', Nature Immunology, vol. 13, pp. 35 - 43, http://dx.doi.org/10.1038/ni.2166
2012
Tangye SG; Deenick EK; Palendira U; Ma CS, 2012, 'T cell-B cell interactions in primary immunodeficiencies', Annals of the New York Academy of Sciences, vol. 1250, pp. 1 - 13, http://dx.doi.org/10.1111/j.1749-6632.2011.06361.x
2012
Randall KL; Chang SS; Ma CS; Fung I; Mei Y; Yabas M; Tan A; Arkwright PD; Suwairi WA; Reyes S; Yamazaki-Nakashimada MA; Garcia-Cruz D; Smart J; Picard C; Okada S; Jouanguy E; Casanova J-L; Lambert T; Cornall RJ; Russell S; Oliaro J; Tangye SG; Bertram EM; Goodnow CC, 2011, 'DOCK8 deficiency impairs CD8 T cell survival and function in humans and mice', Journal of Experimental Medicine, vol. 208, pp. 2305 - 2320, http://dx.doi.org/10.1084/jem.20110345
2011
Tangye SG, 2011, 'Staying alive: Regulation of plasma cell survival', Trends in Immunology, vol. 32, pp. 595 - 602, http://dx.doi.org/10.1016/j.it.2011.09.001
2011
Cannons J; Tangye SG; Schwartzberg P, 2011, 'SLAM family receptors and SAP adaptors in immunity', Annual Review of Immunology, vol. 29, pp. 665 - 705, http://dx.doi.org/10.1146/annurev-immunol-030409-101302
2011
Recher M; Berglund L; Avery D; Cowan M; Gennery AR; Smart J; Peake J; Wong MB; Pai S-Y; Baxi S; Walter J; Palendira U; Tangye GA; Rice M; Brothers S; Al-Herz W; Ottegen H; Eibel H; Puck JM; Cattaneo F; Ziegler JB; Giliani S; Tangye SG; Notarangelo LD, 2011, 'IL-21 is the primary common gamma chain-binding cytokine required for human B-cell differentation in vivo', Blood, vol. 118, pp. 6824 - 6835, http://dx.doi.org/10.1182/blood-2011-06-362533
2011
Palendira U; Low C; Chan A; Hislop A; Ho E; Phan TG; Deenick EK; Cook MC; Riminton DS; Choo S; Loh R; Booth CA; Gaspar HB; Moretta A; Khanna ; Rickinson A; Tangye SG, 2011, 'Molecular pathogeneiss of EBV infection as revealed by analysis of XLP carriers with heterozygous expression of SAP', PLoS Biology, vol. 9, pp. 1 - 17, http://dx.doi.org/10.1371/journal.pbio.1001187
2011
Cho JH; Kim HO; Webster KE; Palendira U; Hahm B; King C; Tangye SG; Sprent J; Kim KS, 2011, 'Calcineurin-dependent negative regulation of CD94/NKG2A expression on naive CD8+ T cells', Blood, vol. 118, pp. 116 - 128, http://dx.doi.org/10.1182/blood-2010-11-317396
2011
Deenick EK; Ma CS; Brink R; Tangye SG, 2011, 'Regulation of T follicular helper cell formation and function by antigen presenting cells', Current Opinion in Immunology, vol. 23, pp. 111 - 118, http://dx.doi.org/10.1016/j.coi.2010.10.007
2011
McGuire HM; Vogelzang A; Ma CS; Hughes WE; Silveira PA; Tangye SG; Christ DU; Fulcher DA; Falcone M; King C, 2011, 'A subset of interleukin-21(+) chemokine receptor CCR9(+) T helper cells target accessory organs of the digestive system in autoimmunity', Immunity, vol. 34, pp. 602 - 615, http://dx.doi.org/10.1016/j.immuni.2011.01.021
2011
Chevalier N; Jarrossay D; Ho E; Avery D; Ma CS; Yu D; Sallusto F; Tangye SG; MacKay CR, 2011, 'CXCR5 expressing human central memory CD4 T Cells and their relevance for humoral immune responses', Journal of Immunology, vol. 186, pp. 5556 - 5568, http://dx.doi.org/10.4049/jimmunol.1002828
2011
Tangye SG, 2011, 'Plasmacytoid DCs induce gutsy plasma cells', Immunity, vol. 34, pp. 144 - 146, http://dx.doi.org/10.1016/j.immuni.2011.02.009
2011
Tangye SG; Tarlinton DM, 2010, 'Memory B cells: Effectors of long-lived immune responses (European Journal of Immunology (2009) 39, (8) DOI 10.1002/eji.200939531)', European Journal of Immunology, vol. 40, pp. 302, http://dx.doi.org/10.1002/eji.200990326
2010
Randall KL; Lambe T; Johnson A; Treanor B; Kucharska E; Domaschenz H; Whittle B; Tze LE; Enders A; Crockford TL; Bouriez-Jones T; Alston D; Cyster JG; Lenardo MJ; MacKay F; Deenick EK; Tangye SG; Chan TD; Camidge T; Brink R; Vinuesa CG; Batista FD; Cornall RJ; Goodnow CC, 2010, 'Erratum: Dock8 mutations cripple B cell immunological synapses, germinal centers and long-lived antibody production (Nature Immunology (2009) 10 (1283-1291))', Nature Immunology, vol. 11, pp. 644, http://dx.doi.org/10.1038/ni0710-644a
2010
Suryani S; Fulcher DA; Santner-Nanan B; Nanan R; Wong MB; Shaw P; Gibson J; Williams A; Tangye SG, 2010, 'Differential expression of CD21 identifies developmentally and functionally distinct subsets of human transitional B cells', Blood, vol. 115, pp. 519 - 529, http://dx.doi.org/10.1182/blood-2009-07-234799
2010
Avery D; Deenick EK; Ma CS; Suryani S; Simpson N; Chew G; Chan TD; Palendira U; Bustamante J; Boisson-Dupuis S; Choo S; Bleasel KE; Peake J; King C; French MA; Engelhard D; Al-Hajjar S; Al-Muhsen S; Magdorf K; Roesler J; Arkwright PD; Hissaria P; Riminton DS; Wong M; Brink R; Fulcher DA; Casanova J-L; Cook MC; Tangye SG, 2010, 'B cell-intrinsic signaling through IL-21 receptor and STAT3 is required for establishing long-lived antibody responses in humans', Journal of Experimental Medicine, vol. 207, pp. 155 - 171, http://dx.doi.org/10.1084/jem.20091706
2010
Simpson N; Gatenby P; Wilson A; Malik S; Fulcher DA; Tangye SG; Manku H; Vyse TJ; Roncador G; Huttley G; Goodnow CC; Vinuesa C; Cook MC, 2010, 'Expansion of circulating T cells resembling follicular T helper cells is a fixed phenotype that identifies a subset of severe systemic lupus erythematosus', Arthritis Care & Research, vol. 62, pp. 234 - 244, http://dx.doi.org/10.1002/art.25032
2010
Tangye SG; Tarlinton DM, 2010, 'Memory B cells: Effectors of long-lived immune responses (vol 39, pg 2065, 2009)', EUROPEAN JOURNAL OF IMMUNOLOGY, vol. 40, pp. 302 - 302, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000274041800032&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
2010
Suryani S; Tangye SG, 2010, 'Therapeutic implications of advances in our understanding of transitional B-cell development in humans', Expert Review of Clinical Immunology, vol. 6, pp. 765 - 775, http://dx.doi.org/10.1586/eci.10.55
2010
Hislop A; Palendira U; Leese AM; Arkwright PD; Rohrlich PS; Tangye SG; Gaspar HB; Lankester AC; Moretta A; Rickinson A, 2010, 'Impaired Epstein-Barr virus-specific CD8+ T-cell function in X-linked lymphoproliferative disease is restricted to SLAM family-positive B-cell targets', Blood, vol. 116, pp. 3249-57, http://dx.doi.org/10.1182/blood-2009-09-238832
2010
Deenick EK; Chan A; Ma CS; Gatto D; Schwartzberg P; Brink R; Tangye SG, 2010, 'Follicular helper T cell differentiation requires continuous antigen presentation that is independent of unique B cell signaling', Immunity, vol. 33, pp. 241 - 253, http://dx.doi.org/10.1016/j.immuni.2010.07.015
2010
Ma CS; Tangye SG; Deenick EK, 2010, 'Human Th9 cells: inflammatory cytokines modulate IL-9 production through the induction of IL-21', Immunology and Cell Biology, vol. 88, pp. 621 - 623, http://dx.doi.org/10.1038/icb.2010.73
2010
Tindall EA; Severi G; Hoang HN; Ma CS; Fernandez P; Southey MC; English DR; Hopper JL; Heyns CF; Tangye SG; Giles GG; Hayes V, 2010, 'Comprehensive analysis of the cytokine-rich chromosome 5q31.1 region suggests a role for IL-4 gene variants in prostate cancer risk', Carcinogenesis, vol. 31, pp. 1748 - 1754, http://dx.doi.org/10.1093/carcin/bgq081
2010
Good K; Avery D; Tangye SG, 2009, 'Resting human memory B cells are intrinsically programmed for enhanced survival and responsiveness to diverse stimuli compared to naive B cells', Journal of Immunology, vol. 182, pp. 890 - 901, http://dx.doi.org/10.4049/jimmunol.182.2.890
2009
Ma CS; Tangye SG, 2009, 'Helping the Helpers!', Immunity, vol. 31, pp. 12 - 14, http://dx.doi.org/10.1016/j.immuni.2009.06.009
2009
Tangye SG; Cook MC, 2009, 'Primary immune deficiencies affecting lymphocyte differentiation: Lessons from the spectrum of resulting infections', International Immunology, vol. 21, pp. 1003 - 1011, http://dx.doi.org/10.1093/intimm/dxp076
2009
Randall KL; Lambe T; Johnson A; Treanor B; Kucharska E; Domaschenz H; Whittle B; Tze LE; Enders A; Crockford TL; Bouriez-Jones T; Alston D; Cyster JG; Lenardo MJ; Mackay F; Deenick EK; Tangye SG; Chan TD; Camidge T; Brink R; Vinuesa C; Batista FD; Cornall RJ; Goodnow CC, 2009, 'Dock8 mutations cripple B cell immunological synapses, germinal centers and long-lived antibody production', Nature Immunology, vol. 10, pp. 1283 - 1291, http://dx.doi.org/10.1038/ni.1820
2009
Ma CS; Suryani S; Avery D; Chan A; Nanan R; Santner-Nanan B; Tangye SG; Deenick E, 2009, 'Early commitment of naive human CD4(+) T cells to the T follicular helper (T(FH)) cell lineage is induced by IL-12', Immunology and Cell Biology, vol. 87, pp. 590 - 600, http://dx.doi.org/10.1038/icb.2009.64
2009
Tangye SG; Tarlinton D, 2009, 'Memory B cells: effectors of long-lived immune responses', European Journal of Immunology, vol. 39, pp. 2065 - 2075, http://dx.doi.org/10.1002/eji.200939531
2009
Fulcher DA; Avery D; Fewings N; Berglund L; Wong S; Riminton D; adelstein S; Tangye SG, 2009, 'Invariant natural killer (iNK) T cell deficiency in patients with common variable immunodeficiency', Clinical and Experimental Immunology, vol. 157, pp. 365 - 369, http://dx.doi.org/10.1111/j.1365-2249.2009.03973.x
2009
Tangye SG; Cook MC; Fulcher DA, 2009, 'Insights into the role of STAT3 in human lymphocyte differentiation as revealed by the hyper-IgE syndrome', Journal of Immunology, vol. 182, pp. 21 - 28, http://dx.doi.org/10.4049/jimmunol.182.1.21
2009
Avery D; Ma C; Bryant V; Santner-Nanan B; Nanan R; Wong MB; Fulcher DA; Cook M; Tangye SG, 2008, 'STAT3 is required for IL-21-induced secretion of IgE from human naive B cells', Blood, vol. 112, pp. 1784 - 1793, http://dx.doi.org/10.1182/blood-2008-02-142745
2008
Chaganti S; Ma C; Bell A; Croom-Carter D; Hislop A; Tangye SG; Rickinson A, 2008, 'Epstein-Barr virus persistence in the absence of conventional memory B cells: IgM(+)IgD(+)CD27(+) B cells harbor the virus in X-linked lymphoproliferative disease patients', Blood, vol. 112, pp. 672 - 679, http://dx.doi.org/10.1182/blood-2007-10-116269
2008
King CK; Tangye SG; MacKay CR, 2008, 'T follicular helper (T-FH) cells in normal and dysregulated immune responses', Annual Review of Immunology, vol. 26, pp. 741 - 766, http://dx.doi.org/10.1146/annurev.immunol.26.021607.090344
2008
Deenick E; Tangye SG, 2008, 'Immunology: Helpful T cells are sticky', Nature, vol. 455, pp. 745 - 746, http://dx.doi.org/10.1038/455745a
2008
Ma CS; Chew G; Simpson N; Priyadarshi A; Wong M; Grimbacher B; Fulcher DA; Tangye SG; Cook M, 2008, 'Deficiency of Th17 cells in hyper IgE syndrome due to mutations in STAT3', Journal of Experimental Medicine, vol. 205, pp. 1551 - 1557, http://dx.doi.org/10.1084/jem.20080218
2008
Deenick EK; Tangye SG, 2008, 'Autoimmunity: IL-21: A new player in Th17-cell differentiation (Immunology and Cell Biology (2007) 85, (503-505) DOI: 10.1038/sj.icb.7100114)', Immunology and Cell Biology, vol. 86, pp. 478, http://dx.doi.org/10.1038/sj.icb.7100152
2008
Rosen DM; Cao W; Avery D; Tangye SG; Liu Y; Houchins J; Lanier L, 2008, 'Functional consequences of interactions between-human NKR-P1A and its ligand LLT1 expressed on activated dendritic cells and B cells', Journal of Immunology, vol. 180, pp. 6508 - 6517, http://dx.doi.org/10.4049/jimmunol.180.10.6508
2008
Avery D; Bryant V; Ma C; Malefyt R; Tangye SG, 2008, 'IL-21-induced isotype switching to IgG and IgA by human naive B cells is differentially regulated by IL-4', Journal of Immunology, vol. 181, pp. 1767 - 1779, http://dx.doi.org/10.4049/jimmunol.181.3.1767
2008
Tangye SG; Avery DT; Bryant VL; Ma CS, 2007, 'Follicular CD4+T helper cells induce human B cells to undergo Ig isotype switching and differentiation to Ig-secreting cells through the production of IL-21', JOURNAL OF IMMUNOLOGY, vol. 178, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000209758202295&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
2007
Deenick E; Tangye SG, 2007, 'Autoimmunity IL-21: a new player in Th17-cell differentiation', Immunology and Cell Biology, vol. 85, pp. 503 - 505, http://dx.doi.org/10.1038/sj.icb.7100114
2007
Mackay F; Groom JR; Tangye SG, 2007, 'An important role for B-cell activation factor and B cells in the pathogenesis of Sjogren`s syndrome', Current Opinion in Rheumatology, vol. 19, pp. 406 - 413, http://dx.doi.org/10.1097/BOR.0b013e328277ef4c
2007
Tangye SG; Good K, 2007, 'Human IgM(+)CD27(+) B cells: Memory B cells or `memory` B cells?', Journal of Immunology, vol. 179, pp. 13 - 19, http://dx.doi.org/10.4049/jimmunol.179.1.13
2007
Good K; Tangye SG, 2007, 'Decreased expression of Kruppel-like factors in memory B cells induces the rapid response typical of secondary antibody responses', Proceedings of the National Academy of Sciences of the United States of America, vol. 104, pp. 13420 - 13425, http://dx.doi.org/10.1073/pnas.0703872104
2007
Ma C; Nichols K; Tangye SG, 2007, 'Regulation of cellular and humoral immune responses by the SLAM and SAP families of molecules', Annual Review of Immunology, vol. 25, pp. 337 - 379, http://dx.doi.org/10.1146/annurev.immunol.25.022106.141651
2007
Bryant V; Ma C; Avery D; Li Y; Good K; Corcoran L; Malefyt R; Tangye SG, 2007, 'Cytokine-mediated regulation of human B cell differentiation into Ig-secreting cells: Predominant role of IL-21 produced by CXCR5(+) T follicular helper cells', Journal of Immunology, vol. 179, pp. 8180 - 8190, http://dx.doi.org/10.4049/jimmunol.179.12.8180
2007
Hare NJ; Ma CS; Alvaro F; Nichols KE; Tangye SG, 2006, 'Missense mutations in SH2D1A identified in patients with X-linked lymphoproliferative disease differentially affect the expression and function of SAP', International Immunology, vol. 18, pp. 1055 - 1065, http://dx.doi.org/10.1093/intimm/dxl039
2006
Tangye S; Mackay F, 2006, 'B Cells and Autoimmunity', The Autoimmune Diseases, pp. 139 - 156, http://dx.doi.org/10.1016/B978-012595961-2/50014-7
2006
Seddiki N; Santner-Nanan B; Tangye SG; Alexander SI; Solomon M; Lee S; Nanan R; Fazekas De Saint Groth B, 2006, 'Persistence of naive CD45RA+ regulatory T cells in adult life', Blood, vol. 107, pp. 2830 - 2838, http://dx.doi.org/10.1182/blood-2005-06-2403
2006
Gu C; Tangye SG; Sun XF; Luo Y; Lin Z; Wu J, 2006, 'The X-linked lymphoproliferative disease gene product SAP associates with PAK-interacting exchange factor and participates in T cell activation', Proceedings of the National Academy of Sciences of the United States of America, vol. 103, pp. 14447 - 14452, http://dx.doi.org/10.1073/pnas.0606624103
2006
Cuss AK; Avery DT; Cannons JL; Yu LJ; Nichols KE; Shaw PJ; Tangye SG, 2006, 'Expansion of functionally immature transitional B cells is associated with human-immunodeficient states characterized by impaired humoral immunity', Journal of Immunology, vol. 176, pp. 1506 - 1516, http://dx.doi.org/10.4049/jimmunol.176.3.1506
2006
Ma CS; Pittaluga S; Avery DT; Hare NJ; Maric I; Klion AD; Nichols KE; Tangye SG, 2006, 'Selective generation of functional somatically mutated IgM +CD27+, but not Ig isotype-switched, memory B cells in X-linked lymphoproliferative disease', Journal of Clinical Investigation, vol. 116, pp. 322 - 333, http://dx.doi.org/10.1007/0-387-34403-9_44
2006
Good K; Bryant V; Tangye SG, 2006, 'Kinetics of human B cell behavior and amplification of proliferative responses following stimulation with IL-21', Journal of Immunology, vol. 177, pp. 5236 - 5247, http://dx.doi.org/10.4049/jimmunol.177.8.5236
2006
Liu SM; Xavier R; Good K; Newton R; Sisavanh M; Zimmer S; Deng C; Silva D; Frost M; Tangye SG; Rolph MS; Mackay C; Chtanova T, 2006, 'Immune cell transcriptome datasets reveal novel leukocyte subset-specific genes and genes associated with allergic processes', Journal of Allergy and Clinical Immunology, vol. 118, pp. 496 - 503, http://dx.doi.org/10.1016/j.jaci.2006.04.040
2006
Tangye SG; Bryant V; Cuss A; Good K, 2006, 'BAFF, APRIL and human B cell disorders', Seminars in Immunology, vol. 18, pp. 305 - 317, http://dx.doi.org/10.1016/j.smim.2006.04.004
2006
Nichols KE; Hom J; Gong SY; Ganguly A; Ma CS; Cannons JL; Tangye SG; Schwartzberg PL; Koretzky GA; Stein PL, 2005, 'Regulation of NKT cell development by SAP, the protein defective in XLP', Nature Medicine, vol. 11, pp. 340 - 345, http://dx.doi.org/10.1038/nm1189
2005
Avery DT; Ellyard JI; Mackay F; Corcoran LM; Hodgkin PD; Tangye SG, 2005, 'Increased expression of CD27 on activated human memory B cells correlates with their commitment to the plasma cell lineage (vol 174, pg 4034, 2005)', JOURNAL OF IMMUNOLOGY, vol. 174, pp. 5885 - 5885, http://dx.doi.org/10.4049/jimmunol.174.9.5885
2005
Ma CS; Hare NJ; Nichols KE; Dupré L; Andolfi G; Roncarolo M-G; Adelstein S; Hodgkin PD; Tangye SG, 2005, 'Impaired humoral immunity in X-linked lymphoproliferative disease is associated with defective IL-10 production by CD4+ T cells', Journal of Clinical Investigation, vol. 115, pp. 1049 - 1059, http://dx.doi.org/10.1172/jci23139
2005
Nichols KE; Ma CS; Cannons JL; Schwartzberg PL; Tangye SG, 2005, 'Molecular and cellular pathogenesis of X-linked lymphoproliferative disease', Immunological Reviews, vol. 203, pp. 180 - 199, http://dx.doi.org/10.1111/j.0105-2896.2005.00230.x
2005
Dupré L; Andolfi G; Tangye SG; Clementi R; Locatelli F; Aricò M; Aiuti A; Roncarolo MG, 2005, 'SAP controls the cytolytic activity of CD8+ T cells against EBV-infected cells', Blood, vol. 105, pp. 4383 - 4389, http://dx.doi.org/10.1182/blood-2004-08-3269
2005
Ma CS; Hare NJ; Nichols KE; Dupré L; Andolfi G; Roncarolo MG; Adelstein S; Hodgkin PD; Tangye SG, 2005, 'Impaired humoral immunity in X-linked lymphoproliferative disease is associated with defective IL-10 production by CD4+ T cells', Journal of Clinical Investigation, vol. 115, pp. 1049 - 1059, http://dx.doi.org/10.1172/JCI200523139
2005
Avery DT; Ellyard JI; Mackay F; Corcoran LM; Hodgkin PD; Tangye SG, 2005, 'Erratum: Increased expression of CD27 on activated human memory B cells correlates with their commitment to the plasma cell lineage (Journal of Immunology (2005) 174 (4034-4042))', Journal of Immunology, vol. 174, pp. 5885
2005
Ma CS; Hodgkin PD; Tangye SG, 2004, 'Automatic generation of lymphocyte heterogeneity: Division-dependent changes in the expression of CD27, CCR7 and CD45 by activated human naive CD4+ T cells are independently regulated', Immunology and Cell Biology, vol. 82, pp. 67 - 74
2004
Ellyard JI; Avery DT; Phan TG; Hare NJ; Hodgkin PD; Tangye SG, 2004, 'Antigen-selected, immunoglobulin-secreting cells persist in human spleen and bone marrow', Blood, vol. 103, pp. 3805 - 3812, http://dx.doi.org/10.1182/blood-2003-09-3109
2004
Hasbold J; Corcoran LM; Tarlinton DM; Tangye SG; Hodgkin PD, 2004, 'Evidence from the generation of immunoglobulin G-secreting cells that stochastic mechanisms regulate lymphocyte differentiation', Nature Immunology, vol. 5, pp. 55 - 63, http://dx.doi.org/10.1038/ni1016
2004
Avery DT; Kalled SL; Ellyard JI; Ambrose C; Bixler SA; Thien M; Brink R; Mackay F; Hodgkin PD; Tangye SG, 2004, 'Erratum: BAFF selectively enhances the survival of plasmablasts generated from human memory B cells (Journal of Clinical Investigation (2003) 112 (286-297) doi:10.1172/JCI200318025)', Journal of Clinical Investigation, vol. 113, pp. 1069, http://dx.doi.org/10.1172/JCI200318025C
2004
Tangye SG; Hodgkin PD, 2004, 'Divide and conquer: The importance of cell division in regulating B-cell responses', Immunology, vol. 112, pp. 509 - 520, http://dx.doi.org/10.1111/j.1365-2567.2004.01950.x
2004
Avery DT; Kalled SL; Ellyard JI; Ambrose C; Bixler SA; Thien M; Brink R; Mackay F; Hodgkin PD; Tangye SG, 2003, 'BAFF selectively enhances the survival of plasmablasts generated from human memory B cells', Journal of Clinical Investigation, vol. 112, pp. 286 - 297, http://dx.doi.org/10.1172/jci200318025
2003
Tangye SG; Avery DT; Deenick EK; Hodgkin PD, 2003, 'Intrinsic differences in the proliferation of naive and memory human B cells as a mechanism for enhanced secondary immune responses', Journal of Immunology, vol. 170, pp. 686 - 694, http://dx.doi.org/10.4049/jimmunol.170.2.686
2003
Avery DT; Kalled SL; Ellyard JI; Ambrose C; Bixler SA; Thien M; Brink R; MacKay F; Hodgkin PD; Tangye SG, 2003, 'BAFF selectively enhances the survival of plasmablasts generated from human memory B cells', Journal of Clinical Investigation, vol. 112, pp. 286 - 297, http://dx.doi.org/10.1172/JCI18025
2003
Tangye SG; Nichols KE; Hare NJ; Van de Weerdt BCM, 2003, 'Functional requirements for interactions between CD84 and Src homology 2 domain-containing proteins and their contribution to human T cell activation', Journal of Immunology, vol. 171, pp. 2485 - 2495, http://dx.doi.org/10.4049/jimmunol.171.5.2485
2003
Tangye SG; Avery DT; Hodgkin PD, 2003, 'A division-linked mechanism for the rapid generation of Ig-secreting cells from human memory B cells', Journal of Immunology, vol. 170, pp. 261 - 269, http://dx.doi.org/10.4049/jimmunol.170.1.261
2003
Tangye SG; Ferguson A; Avery DT; Ma CS; Hodgkin PD, 2002, 'Isotype switching by human B cells is division-associated and regulated by cytokines', Journal of Immunology, vol. 169, pp. 4298 - 4306, http://dx.doi.org/10.4049/jimmunol.169.8.4298
2002
Tangye SG; Van De Weerdt BCM; Avery DT; Hodgkin PD, 2002, 'CD84 is up-regulated on a major population of human memory B cells and recruits the SH2 domain containing proteins SAP and EAT-2', European Journal of Immunology, vol. 32, pp. 1640 - 1649, http://dx.doi.org/10.1002/1521-4141(200206)32:6<1640::AID-IMMU1640>3.0.CO;2-S
2002
Weston KM; Tangye SG; Dunn RD; Smith A; Morris MB; Raison RL, 2001, 'IgM expressed by leukemic CD5+ B cells binds mouse immunoglobulin light chain', Journal of Molecular Recognition, vol. 14, pp. 245 - 253, http://dx.doi.org/10.1002/jmr.539
2001
Baker JE; Majeti R; Tangye SG; Weiss A, 2001, 'Protein tyrosine phosphatase CD148-mediated inhibition of T-cell receptor signal transduction is associated with reduced LAT and phospholipase Cγ1 phosphorylation', Molecular and Cellular Biology, vol. 21, pp. 2393 - 2403, http://dx.doi.org/10.1128/MCB.21.7.2393-2403.2001
2001
Tangye SG; Phillips JH; Lanier LL; Nichols KE, 2000, 'Cutting edge: Functional requirement for SAP in 2B4-mediated activation of human natural killer cells as revealed by the X-linked lymphoproliferative syndrome', Journal of Immunology, vol. 165, pp. 2932 - 2936, http://dx.doi.org/10.4049/jimmunol.165.6.2932
2000
Tangye SG; Phillips JH; Lanier LL, 2000, 'The CD2-subset of the Ig superfamily of cell surface molecules: Receptor-ligand pairs expressed by NK cells and other immune cells', Seminars in Immunology, vol. 12, pp. 149 - 157, http://dx.doi.org/10.1006/smim.2000.0217
2000
Tangye SG; Cherwinski H; Lanier LL; Phillips JH, 2000, '2B4-mediated activation of human natural killer cells', Molecular Immunology, vol. 37, pp. 493 - 501, http://dx.doi.org/10.1016/S0161-5890(00)00076-6
2000
Castro AG; Hauser TM; Cocks BG; Abrams J; Zurawski S; Churakova T; Zonin F; Robinson D; Tangye SG; Aversa G; Nichols KE; De Vries JE; Lanier LL; O'Garra A, 1999, 'Molecular and functional characterization of mouse signaling lymphocytic activation molecule (SLAM): Differential expression and responsiveness in Th1 and Th2 cells', Journal of Immunology, vol. 163, pp. 5860 - 5870
1999
Tangye SG; Lazetic S; Woollatt E; Sutherland GR; Lanier LL; Phillips JH, 1999, 'Cutting edge: Human 2B4, an activating NK cell receptor, recruits the protein tyrosine phosphatase SHP-2 and the adaptor signaling protein SAP', Journal of Immunology, vol. 162, pp. 6981 - 6985
1999
Tangye SG; Aversa G; Lanier LL; De Vries JE; Phillips JH, 1998, 'CD148: A cell-surface phosphatase involved in T cell activation', FASEB Journal, vol. 12
1998
Tangye SG; Liu YJ; Aversa G; Phillips JH; De Vries JE, 1998, 'Identification of functional human splenic memory B cells by expression of CD148 and CD27', Journal of Experimental Medicine, vol. 188, pp. 1691 - 1703, http://dx.doi.org/10.1084/jem.188.9.1691
1998
Tangye SG; Weston KM; Raison RL, 1998, 'Interleukin-10 inhibits the in vitro proliferation of human activated leukemic CD5+ B-Cells', Leukemia and Lymphoma, vol. 31, pp. 121 - 130, http://dx.doi.org/10.3109/10428199809057592
1998
Tangye SG; Phillips JH; Lanier LL; De Vries JE; Aversa G, 1998, 'CD148: A receptor-type protein tyrosine phosphatase involved in the regulation of human T cell activation', Journal of Immunology, vol. 161, pp. 3249 - 3255
1998
Tangye SG; Wu J; Aversa G; De Vries JE; Lanier LL; Phillips JH, 1998, 'Cutting edge: Negative regulation of human T cell activation by the receptor-type protein tyrosine phosphatase CD148', Journal of Immunology, vol. 161, pp. 3803 - 3807
1998
Tangye SG; Weston KM; Raison RL, 1997, 'Cytokines and cross-linking of sIgM augment PMA-induced activation of human leukaemic CD5+ B cells', Immunology and Cell Biology, vol. 75, pp. 561 - 567, http://dx.doi.org/10.1038/icb.1997.87
1997
Tangye SG; Raison RL, 1997, 'Human cytokines suppress apoptosis of leukaemic CD5+ B cells and preserve expression of bcl-2', Immunology and Cell Biology, vol. 75, pp. 127 - 135, http://dx.doi.org/10.1038/icb.1997.17
1997
Tangye SG; Raison RL, 1996, 'Leukaemic CD5+ B-cell apoptosis: Co-incidence of cell death and DNA fragmentation with reduced bcl-2 expression', British Journal of Haematology, vol. 92, pp. 950 - 953, http://dx.doi.org/10.1046/j.1365-2141.1996.427965.x
1996
TANGYE SG; WESTON KM; RAISON RL, 1995, 'Phorbol ester activates CD5+ leukaemic B cells via a T cell‐independent mechanism', Immunology and Cell Biology, vol. 73, pp. 44 - 51, http://dx.doi.org/10.1111/j.1440-1711.1995.tb03832.x
1995
Conference Abstracts
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Masle-Farquhar E; Payne K; Jackson K; Rao G; Singh M; El-Eryani G; Brink R; Tangye S; Reed J; Goodnow C, 2019, 'The effects of germline STAT3-activating mutations from autoimmunity and lymphoid malignancy on mouse and human T cell development and function', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY, Beijing, PEOPLES R CHINA, Vol. 49, pp. 901 - 901, presented at 17th International Congress of Immunology of the International-Union-of-Immunological-Societies (IUIS), Beijing, PEOPLES R CHINA, 19 October 2019 - 23 October 2019, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000490026902546&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2019
Yap JY; Gloss B; Batten M; Hsu P; Berglund L; Polizzotto M; Kirk E; Deenick E; Ma C; Tangye S; Phan TG, 2019, 'EVEROLIMUS-INDUCED REMISSION OF KAPOSI'S SARCOMA SECONDARY TO CRYPTIC CTLA4 SPLICING AND HAPLOINSUFFICIENCY', in INTERNAL MEDICINE JOURNAL, WILEY, Vol. 49, pp. 35 - 36, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000488891400106&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2019
Tri GP; Tangye S; Wong M; Gray P; Batten M; Goodnow C; Burnett L, 2018, 'CLINICAL IMPACT OF WHOLE GENOME SEQUENCING ON THE DIAGNOSIS AND MANAGEMENT OF PATIENTS WITH PRIMARY IMMUNODEFICIENCY DISEASES - THE CLINICAL IMMUNOGENOMICS RESEARCH CONSORTIUM AUSTRALIA (CIRCA) EXPERIENCE', in INTERNAL MEDICINE JOURNAL, WILEY, Vol. 48, pp. 29 - 29, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000449673000079&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2018
Jing H; Abolhassani H; Edwards ESJ; Ikinciogullari KA; Borte S; Buggert M; Du L; Lennikov M; Romano R; Caridha R; Bade S; Zhang Y; Frederiksen J; Fang M; Bal SK; Haskologlu S; Dogu F; Tacyildiz N; Matthews HF; McElwee JJ; Gostick E; Price DA; Palendira U; Aghamohammadi A; Boisson B; Rezaei N; Karlsson A; Lenardo MJ; Casanova J-L; Hammarstrom L; Tangye SG; Pan-Hammarstrom Q; Su HC, 2017, 'COMBINED IMMUNODEFICIENCY AND EPSTEIN-BARR VIRUS-INDUCED B CELL MALIGNANCY IN HUMANS WITH INHERITED CD70 DEFICIENCY', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, Seattle, WA, Vol. 37, pp. 230 - 230, presented at CIS Annual Meeting on Immune Deficiency and Dysregulation North American, Seattle, WA, 23 March 2017 - 26 March 2017, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000396924700093&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2017
Vijayan D; Redzwan MN; Avery D; Wirasinha R; Brink R; Walters G; Adelstein S; Kobayashi M; Gray P; Elliott M; King C; Vinuesa C; Ghilardi N; Ma C; Tangye S; Batten M, 2016, 'IL-27 directly influences germinal center B cell development via STAT1', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY-BLACKWELL, Melbourne, AUSTRALIA, Vol. 46, pp. 1082 - 1082, presented at International Congress of Immunology (ICI), Melbourne, AUSTRALIA, 21 August 2016 - 26 August 2016, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000383610402571&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2016
Tangye S, 2016, 'Intrinsic functional defects in human lymphocytes: insights into disease pathogenesis of primary immunodeficiencies', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY-BLACKWELL, Melbourne, AUSTRALIA, Vol. 46, pp. 1000 - 1000, presented at International Congress of Immunology (ICI), Melbourne, AUSTRALIA, 21 August 2016 - 26 August 2016, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000383610402407&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2016
Pillay BA; Ma CS; Casanova JL; Uzel G; Tangye SG, 2016, 'Using immunodeficiency patient cells in in vitro cultures to provide insight into T-helper cell differentiation', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY-BLACKWELL, Melbourne, AUSTRALIA, Vol. 46, pp. 988 - 989, presented at International Congress of Immunology (ICI), Melbourne, AUSTRALIA, 21 August 2016 - 26 August 2016, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000383610402382&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
2016
Edwards ESJ; Cole T; Wong M; Uzel G; Tangye SG, 2016, 'Effect of gain-of-function mutations in PI3 kinase p110d on the phenotype and function of EBV-specific CD8(+) T-cells', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY-BLACKWELL, Melbourne, AUSTRALIA, Vol. 46, pp. 980 - 981, presented at International Congress of Immunology (ICI), Melbourne, AUSTRALIA, 21 August 2016 - 26 August 2016, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000383610402365&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2016
Kane A; Lau A; Brink R; Tangye S; Deenick E, 2016, 'STAT3 is a critical B-cell intrinsic regulator of functional antibody responses and IgE production', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY-BLACKWELL, Melbourne, AUSTRALIA, Vol. 46, pp. 849 - 849, presented at International Congress of Immunology (ICI), Melbourne, AUSTRALIA, 21 August 2016 - 26 August 2016, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000383610402097&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2016
Pelham SJ; Lenthall H; Deenick EK; Tangye SG, 2016, 'Mutations underlying autosomal dominant hyper-IgE syndrome impair distinct stages of STAT3 signaling', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY-BLACKWELL, Melbourne, AUSTRALIA, Vol. 46, pp. 139 - 140, presented at International Congress of Immunology (ICI), Melbourne, AUSTRALIA, 21 August 2016 - 26 August 2016, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000383610400280&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
2016
Butt D; Chan T; Bourne K; Hermes J; Strasser A; Tangye S; Phan T; Rao VK; Brink R, 2016, 'Rogue germinal center B cells: unconventional lymphocytes released by FAS inactivation that drive IgE and autoantibody production', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY-BLACKWELL, Melbourne, AUSTRALIA, Vol. 46, pp. 25 - 26, presented at International Congress of Immunology (ICI), Melbourne, AUSTRALIA, 21 August 2016 - 26 August 2016, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000383610400052&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2016
Woon H; Braun A; Li J; Smith C; Edwards J; Sierro F; Feng C; Khanna R; Elliot M; Tangye S; Rickinson A; Gebhardt T; Britton W; Palendira M, 2016, 'IL-15 and TGF-beta promote the selective retention of virus-specific resident memory T cells in human lymphoid organs', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY-BLACKWELL, Melbourne, AUSTRALIA, Vol. 46, pp. 57 - 57, presented at International Congress of Immunology (ICI), Melbourne, AUSTRALIA, 21 August 2016 - 26 August 2016, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000383610400113&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2016
Bosch B; Dockx S; Tangye SG; Meyts I; Moens L, 2016, 'IPEX ... ARE ALL FEMALE CARRIERS HEALTHY?', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, Boston, MA, Vol. 36, pp. 252 - 252, presented at CIS Annual Meeting on Immune Deficiency and Dysregulation North American Conference, Boston, MA, 14 April 2016 - 17 April 2016, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000372165300050&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2016
Nguyen A; Moran I; Tanaka M; Tangye S; Brink R; Phan T, 2016, 'Dynamic changes in gene regulatory networks control subcapsular sinus macrophage fate and function', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY-BLACKWELL, Melbourne, AUSTRALIA, Vol. 46, pp. 430 - 430, presented at International Congress of Immunology (ICI), Melbourne, AUSTRALIA, 21 August 2016 - 26 August 2016, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000383610401057&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2016
Tangye SG, 2016, 'DEFECTS IN HUMAN B-CELL DEVELOPMENT AND DIFFERENTIATION DUE TO DISEASE-CAUSING MUTATIONS IN THE PI3K PATHWAY', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, Boston, MA, Vol. 36, pp. 298 - 299, presented at CIS Annual Meeting on Immune Deficiency and Dysregulation North American Conference, Boston, MA, 14 April 2016 - 17 April 2016, http://dx.doi.org/10.1007/s10875-016-0237-x
2016
Suan D; Krautler N; Maag J; Butt D; Wood K; Hermes J; Priestley D; Statham A; Elliott M; Marcel D; Basten A; Tangye S; Brink R, 2016, 'Memory B cells develop from low-affinity clones in the germinal center light zone and are identified by CCR6 expression in mice and humans', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY-BLACKWELL, Melbourne, AUSTRALIA, Vol. 46, pp. 1132 - 1133, presented at International Congress of Immunology (ICI), Melbourne, AUSTRALIA, 21 August 2016 - 26 August 2016, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000383610402674&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2016
Martinez-Barricarte R; Aytekin C; Markle J; Kong X-F; Fleckenstein B; Tangye SG; van de Vosse E; Boisson-Dupuis S; Bustamante J; Casanova J-L, 2016, 'INHERITED IL-12R beta 2 DEFICIENCY CAUSES MYCOBACTERIAL SUSCEPTIBILITY', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, Boston, MA, Vol. 36, pp. 270 - 270, presented at CIS Annual Meeting on Immune Deficiency and Dysregulation North American Conference, Boston, MA, 14 April 2016 - 17 April 2016, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000372165300095&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
2016
Jandl C; Liu SM; Nieto FDCP; Warren J; Hughes WE; Vogelzang A; Webster K; Craig M; Uzel G; Tangye S; Dent A; Vinuesa C; Sprent J; King C, 2016, 'Interleukin-21 limits regulatory T cell populations by modulating responsiveness to Interleukin-2', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY-BLACKWELL, Melbourne, AUSTRALIA, Vol. 46, pp. 102 - 102, presented at International Congress of Immunology (ICI), Melbourne, AUSTRALIA, 21 August 2016 - 26 August 2016, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000383610400203&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2016
Martinez-Barricarte R; Kong X-F; Kennedy J; Lazarov T; Deenick E; Ma C; Mele F; Trouillet C; Bousfiha A; Aytekin C; Picard C; Salem S; Langlais D; Lasseau T; Migaud M; Abel L; Boisson-Dupuis S; Hambleton S; B S; Geissmann F; Tangye S; Sallusto F; Bustamante J; Gros P; Casanova J-L, 2016, 'Mycobacterial disease and myeloid dendritic cells defects in patients with SPPL2a deficiency', in EUROPEAN JOURNAL OF IMMUNOLOGY, WILEY-BLACKWELL, Melbourne, AUSTRALIA, Vol. 46, pp. 777 - 778, presented at International Congress of Immunology (ICI), Melbourne, AUSTRALIA, 21 August 2016 - 26 August 2016, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000383610401757&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2016
Williams KW; Edwards E; Stoddard JL; Martinez B; Chen CC; Agharahimi A; Hussey AA; Niemala JE; Holland SM; Tangye SG; Uzel G, 2015, 'PRELIMINARY DATA FOR mTOR INHIBITOR TREATMENT IN PATIENTS WITH OF GAIN-OF-FUNCTION MUTATIONS IN PIK3CD', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, Houston, TX, Vol. 35, pp. 314 - 315, presented at North American Annual Conference of the Clinical-Immunology-Society (CIS) on Immune Deficiency and Dysregulation, Houston, TX, 09 April 2015 - 12 April 2015, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000351510200043&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
2015
Markle J; Okada S; Deenick E; Mele F; Averbuch D; Lagos M; Gonzalez M; Alzahrani M; Soudais C; Henderson L; Deswarte C; Jabot-Hanin F; Martinez-Barricarte R; Itan Y; Boisson B; Cooper A; Picard C; Abel L; Notarangelo L; Boisson-Dupuis S; Puel A; Sallusto F; Bustamante J; Tangye S; Casanova J-L, 2015, 'Impairment of IL-17A/F Immunity to Candida and IFN-g Immunity to Mycobacterium in Patients with RORC Deficiency', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, Buenos Aires, ARGENTINA, Vol. 35, pp. S13 - S14, presented at 4th Meeting of the Latin-American-Society-for-Immunodeficiencies (LASID), Buenos Aires, ARGENTINA, 18 November 2015 - 21 November 2015, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000363977700030&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2015
Frith K; O'Brien T; Tangye S; Sutton R; Ziegler J; Gray P, 2014, 'XLP-Associated Cerebral Vasculitis Successfully Treated with Bone Marrow Transplant', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, Prague, CZECH REPUBLIC, Vol. 34, pp. S241 - S241, presented at 16th Biennial Meeting of the European-Society-for-Immunodeficiencies, Prague, CZECH REPUBLIC, 29 October 2014 - 01 November 2014, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000347389100212&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
2014
Reports
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Bryant VL; Tangye SG, 2016, The Expanding Spectrum of NFkB1 Deficiency, http://dx.doi.org/10.1007/s10875-016-0310-5
2016
Tangye SG, 2016, Genetic cause of immune dysregulation one gene or two?, http://dx.doi.org/10.1172/JCI90831
2016
Ma CS; Tangye SG, 2016, Immunology: Cytotoxic T cells that escape exhaustion, http://dx.doi.org/10.1038/nature19428
2016
Conference Papers
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Schwartzberg P; Cannons J; Zhao P; Reilley J; Kapnick S; Tangye S; Uzel G, 2014, 'Defects in CD8 Cytolysis in Immunodeficiencies with Impaired EBV Clearance', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, Prague, CZECH REPUBLIC, pp. S491 - S492, presented at 16th Biennial Meeting of the European-Society-for-Immunodeficiencies, Prague, CZECH REPUBLIC, 29 October 2014 - 01 November 2014, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000347389100757&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2014
Deenick EK; Ives ML; Wilson RP; Uzel G; Tangye SG, 2014, 'The Role of STAT3 in the Differentiation and Function of Unconventional T Cells', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, Prague, CZECH REPUBLIC, pp. S441 - S441, presented at 16th Biennial Meeting of the European-Society-for-Immunodeficiencies, Prague, CZECH REPUBLIC, 29 October 2014 - 01 November 2014, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000347389100651&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
2014
Markle J; Okada S; Deenick E; Mele F; Wong N; Ma CS; Soudais C; Averbuch D; Alzahrani M; Lagos M; Gonzalez M; Martinez-Baricarte R; Okada C; Migaud M; Itan Y; Picard C; Lantz O; Abel L; Engelhard D; Al-Muhsen S; Sallusto F; Boisson-Dupuis S; Puel ANNE; Bustamante J; Tange S; Casanova JL, 2014, 'Dual Impairment of IL-17 and IFN-G Immunity Cause Infections by Candida and Mycobacterium in Humans with RORC Deficiency', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, Prague, CZECH REPUBLIC, pp. S485 - S486, presented at 16th Biennial Meeting of the European-Society-for-Immunodeficiencies, Prague, CZECH REPUBLIC, 29 October 2014 - 01 November 2014, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000347389100745&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2014
Martinez-Barricarte R; Aytekin C; Markle J; Knog XF; Fleckenstein B; Tangye S; van de Vosse E; Boisson-Dupuis S; Bustamante J; Casanova JL, 2014, 'Inherited IL-12R beta 2 Complete Deficiency Predisposes to BCG Disease and Tuberculosis', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, Prague, CZECH REPUBLIC, pp. S488 - S488, presented at 16th Biennial Meeting of the European-Society-for-Immunodeficiencies, Prague, CZECH REPUBLIC, 29 October 2014 - 01 November 2014, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000347389100750&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2014
Uzel G; Kuehn HS; Weiming Q; Lo B; Deenick EK; Niemela JE; Avery DT; Schickel JN; Tran DQ; Stoddard J; Zhang Y; Frucht DM; Rao KV; Su HC; Notarangelo LD; Olivier KN; McElwee J; Pittaluga S; Oliveira JB; Meffre E; Fleisher TA; Holland SM; Tangye SG; Lenardo MJ, 2014, 'Human CTLA4 Haploinsufficiency Causes Severe Immune Dysregulation', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, Prague, CZECH REPUBLIC, pp. S144 - S145, presented at 16th Biennial Meeting of the European-Society-for-Immunodeficiencies, Prague, CZECH REPUBLIC, 29 October 2014 - 01 November 2014, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000347389100011&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2014
Uzel G; Stoddard J; Martinez B; Agharahimi A; Hussey AA; Folio LR; Pittaluga S; Fleisher TA; Tangye SG; Holland SM, 2014, 'A Short-Term Treatment Summary Using M-TOR Inhibitors in Patients with Germline PIK3CD Mutations: Prospects for Future', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, Prague, CZECH REPUBLIC, pp. S164 - S164, presented at 16th Biennial Meeting of the European-Society-for-Immunodeficiencies, Prague, CZECH REPUBLIC, 29 October 2014 - 01 November 2014, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000347389100044&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2014
Ma CS; Wong N; Avery DT; Torpy J; Stoddard JL; Kobayashi M; Deenick EK; Casanova JL; Uzel G; Tangye SG, 2014, 'Determining the Molecular Requirements for Generating Human T Follicular Helper (Tfh) Cells', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, Prague, CZECH REPUBLIC, pp. S458 - S459, presented at 16th Biennial Meeting of the European-Society-for-Immunodeficiencies, Prague, CZECH REPUBLIC, 29 October 2014 - 01 November 2014, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000347389100688&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
2014
Hsu P; Wong N; Avery DT; Torpy J; Gray PE; Fulcher DA; Uzel G; Williams A; Wong M; Campbell DE; Tangye SG, 2014, 'Rare STAT1 GOF Mutation in Dna Binding Domain Causing Mild CMC', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, Prague, CZECH REPUBLIC, pp. S451 - S451, presented at 16th Biennial Meeting of the European-Society-for-Immunodeficiencies, Prague, CZECH REPUBLIC, 29 October 2014 - 01 November 2014, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000347389100672&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2014
Gray P; Walsh C; Zhu Y; Elakis G; Mullan G; Lo W; Lee E; Cowley M; Dinger M; Buckley M; Ziegler J; Tangye S; Roscioli T, 2014, 'Extrapulmonary Non-Tuberculous Mycobacterial Infection in a Child with Autosomal Dominant Hyper IgE Syndrome', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, Prague, CZECH REPUBLIC, pp. S499 - S500, presented at 16th Biennial Meeting of the European-Society-for-Immunodeficiencies, Prague, CZECH REPUBLIC, 29 October 2014 - 01 November 2014, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000347389100775&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2014
Jackson CC; Byun M; Ma CS; Akcay A; Pedergnana V; Palendira U; Myoung J; Avery DT; Liu Y; Abhyankar A; Lorenzo L; Schmidt M; Lim HK; Cassar O; Migaud M; Rozenberg F; Canpolat N; Aydogan G; Fleckenstein B; Bustamante J; Picard C; Gessain A; Jouanguy E; Cesarman E; Olivier M; Gros P; Abel L; Croft M; Tangye SG; Casanova J-L, 2014, 'INHERITED HUMAN OX40 DEFICIENCY UNDERLYING CLASSIC KAPOSI SARCOMA OF CHILDHOOD', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, Antalya, TURKEY, pp. 702 - 703, presented at 100th J Project Meeting, Antalya, TURKEY, 12 March 2014 - 14 March 2014, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000341839800038&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2014
Tangye SG; Stoddard JL; Ma CS; Wong N; Hsu AP; Fleisher TA; Pittaluga S; Holland SM; Uzel G, 2014, 'Primary Immune Deficiencies Help to Reveal Molecular Requirements for Human T Follicular Helper Cells', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, Baltimore, MD, pp. 360 - 360, presented at Primary Immune Deficiency Diseases North American Conference of the Clinical-Immunology-Society (CIS), Baltimore, MD, 10 April 2014 - 13 April 2014, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000336046800055&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2014
Barricarte RM; Aytekin C; Markle J; Kong XF; Fleckenstein B; Tangye S; van de Vosse E; Boisson-Dupuis S; Bustamante J; Casanova JL, 2014, 'Inherited IL-12R?2 Complete Deficiency Predisposes to BCG Disease and Tuberculosis', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, Prague, CZECH REPUBLIC, pp. S253 - S254, presented at 16th Biennial Meeting of the European-Society-for-Immunodeficiencies, Prague, CZECH REPUBLIC, 29 October 2014 - 01 November 2014, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000347389100240&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2014
Stoddard JL; Hsu AP; Hussey AA; Agharahimi A; Holland SM; Fleisher TA; Tangye SG; Uzel G, 2014, 'Beyond T, B, and NK Flow: An Extended Analytical Panel for the Flow Cytometric Evaluation of Primary Immune Deficiencies', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, Baltimore, MD, pp. 366 - 366, presented at Primary Immune Deficiency Diseases North American Conference of the Clinical-Immunology-Society (CIS), Baltimore, MD, 10 April 2014 - 13 April 2014, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000336046800076&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2014
Kong XF; Lasseau T; Trouillet C; Bousfiha A; Aytekin C; Deswarte C; Boisson-Dupuis S; Vogt G; Gros P; Tangye S; Geissmann F; Bustamante J; Casanova JL, 2014, 'A New Genetic Disorder Predispose Mendelian Susceptibility to Mycobacterial Diseases', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, Prague, CZECH REPUBLIC, pp. S140 - S141, presented at 16th Biennial Meeting of the European-Society-for-Immunodeficiencies, Prague, CZECH REPUBLIC, 29 October 2014 - 01 November 2014, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000347389100003&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2014
Hsu P; Wong N; Avery DT; Torpy J; Gray P; Fulcher DA; Uzel G; Williams A; Wong M; Campbell D; Tangye SG, 2014, 'RARE STAT1 GOF MUTATION IN DNA BINDING DOMAIN CAUSING MILD CMC', in INTERNAL MEDICINE JOURNAL, WILEY-BLACKWELL, pp. 5 - 5, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000342722800016&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2014
Redzwan NM; Vijayan D; Ma C; Tangye S; Brink R; Vinuesa C; Batten M, 2013, 'IL-27 signals to both B and T cells support germinal center function and the development of GC-driven lupus', in CYTOKINE, ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD, San Francisco, CA, pp. 292 - 292, presented at Annual Joint Conference of the International-Cytokine-Society and the International-Society-for-Interferon-and-Cytokine-Research, San Francisco, CA, 29 September 2013 - 03 October 2013, http://dx.doi.org/10.1016/j.cyto.2013.06.210
2013
Berglund LJ; Cook M; Wong M; Fulcher D; Adelstein S; Arkwright P; Ziegler J; Smart J; Tangye SG, 2012, 'IL-2 ENHANCES THE EFFECTS OF IL-21 ON HUMORAL IMMUNE RESPONSES IN HUMANS', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, Florence, ITALY, pp. 280 - 280, presented at 15th Biennial Meeting European-Society-for-Immunodeficiency (ESID), Florence, ITALY, 03 October 2012 - 06 October 2012, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000308728900572&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2012
Recher M; Deenick E; Al-Herz W; Frugoni F; Lee Y; Delmonte OM; Giliani S; Walter JE; Berger CT; Nobre R; Roscioli T; Buckley MF; Ziegler JB; Wong M; Megarbane A; Chouery E; Lefranc G; Hess C; Tangye S; Notarangelo LD; Bloch D, 2012, 'SP110 REGULATES NUCLEAR ORPHAN RECEPTOR NUR77-DRIVEN APOPTOSIS IN T CELLS', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, Florence, ITALY, pp. 20 - 21, presented at 15th Biennial Meeting European-Society-for-Immunodeficiency (ESID), Florence, ITALY, 03 October 2012 - 06 October 2012, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000308728900036&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2012
Ives M; Ma C; Palendira U; French MA; Choo S; Smart J; Wong M; Arkwright PD; Fulcher DA; Cook MC; Casanova J-L; Tangye SG; Deenick EK, 2012, 'PRIMARY IMMUNE DEFICIENCIES REVEAL THE ROLE OF STAT1 AND STAT3 IN THE ACTIVATION AND DIFFERENTIATION OF HUMAN CD8(+) T CELLS', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, Florence, ITALY, pp. 311 - 312, presented at 15th Biennial Meeting European-Society-for-Immunodeficiency (ESID), Florence, ITALY, 03 October 2012 - 06 October 2012, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000308728900636&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2012
Byun M; Ma CS; Akcay A; Canpolat N; Aydogan G; Abhyankar A; Pedergnana V; Lorenzo L; Schmidt M; Mueller-Fleckenstein I; Picard C; Lim H-K; Migaud M; Bustamante J; Gessain A; Plancoulaine S; Cesarman E; Croft M; Abel L; Jouanguy E; Tangye SG; Casanova J-L, 2012, 'A NEW PRIMARY IMMUNODEFICIENCY AFFECTING T CELLS IN A PATIENT WITH KAPOSI SARCOMA AND LEISHMANIASIS', in JOURNAL OF CLINICAL IMMUNOLOGY, SPRINGER/PLENUM PUBLISHERS, Florence, ITALY, pp. 384 - 384, presented at 15th Biennial Meeting European-Society-for-Immunodeficiency (ESID), Florence, ITALY, 03 October 2012 - 06 October 2012, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000308728900731&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2012
Chagantl S; Ma C; Bell A; Croom-Carter D; Hislop A; Tangye SG; Rickinson A, 2008, 'High level EBV persistence in the IgM + IgD+CD27+B cell subset in patients with X-linked lymphoproliferative disease lacking isotype-switched memory B cells', in British Journal of Haematology, Blackwell Publishing Ltd, Oxford, England, pp. 19 - 20, presented at Abstracts of the British Society of Haematology 48th Annual Scientific Meeting, incorporating the 6th Bi-Annual I-BFM Leukaemia Symposium, Glasgow, SCOTLAND, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000255032500054&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
2008
Chaganti S; Ma C; Bell A; Croom-Carter D; Hislop A; Tangye S; Rickinson A, 2007, 'High level EBV persistence in the IgM(+) IgD(+) CD27(+) B cell subset in patients with X-linked lymphoproliferative disease lacking isotype-switched memory B cells', in BLOOD, AMER SOC HEMATOLOGY, Atlanta, GA, pp. 675A - 675A, presented at 49th Annual Meeting of the American-Society-of-Hematology, Atlanta, GA, 08 December 2007 - 11 December 2007, http://dx.doi.org/10.1182/blood.V110.11.2276.2276
2007
Book Chapters
add
Tangye SG; Fulcher DA, 2010, 'The Role of BAFF and APRIL in Regulating Human B-Cell Behaviour: Implications for Disease Pathogenesis', in Cancro MP (ed.), BLYS LIGANDS AND RECEPTORS, edn. Contemporary Immunology, HUMANA PRESS INC, pp. 195 - 220, http://dx.doi.org/10.1007/978-1-60327-013-7_9
2010
Tangye SG; Fulcher DA, 2010, 'The role of BAFF and APRIL in regulating human B-cell behaviour: implications for disease pathogenesis', in Cancro MP (ed.), BLys Ligands and Receptors, edn. X111, Humana Press, pp. 195 - 220, http://dx.doi.org/10.1007/978-1-60327-013-7
2010