Qian Garrett

Visiting Senior Fellow

A/Professor Qian Garrett is the Director of Research Office, the University of Notre Dame Australia,exercising leadership in all matters involving research; responsible for the development of research culture, oversight of higher degree by research student training, and building research partnerships.

A/Professor Garrett has over 20 years of experience in biomedical research and product development. She has led many successful high-impact projects on research and commercialisation of technology in therapeutics and biomedical devices for prevention and treatment of ocular wounds/defects and dry eyes, and for vision correction.

A/Professor Garrett is a Senior Visiting Fellow of the SOVS. She has supervised 20 research (doctoral and honours) students in the fields of ocular wound healing, dry eyes, physiology of the ocular surface, biocompatibility and comfort wear of contact lenses. A/Professor Garrett has secured over $2.5M of external funding as a lead investigator. She has led and co-authored more than 70 publications (book chapters, journal articles, patents and conference papers).

A/Professor Garrett completed her Ph.D. at the Graduate School of Biomedical Engineering, UNSW Australia. She was a Wellcome Trust Research Fellow at the Institute of Ophthalmology, University College London (UK). She was a Japanese Science & Technology Agency Research Fellow at the Takasaki Radiation Chemistry Research Establishment, Japan. Prior to joining the University of Notre Dame Australia, A/Professor Garrett was a Senior Research Fellow and Manager of the Biological Sciences at the Brien Holden Vision Institute, and the Research Development and Program Coordinator at the Centre for Oncology Education and Research Translation, Australia.

publications

Journal articles
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Lee L; Garrett Q; Flanagan J; Chakrabarti S; Papas E, 2018, 'Genetic factors and molecular mechanisms in dry eye disease', Ocular Surface, vol. 16, pp. 206 - 217, http://dx.doi.org/10.1016/j.jtos.2018.03.003
2018
Zhang R; Garrett Q; Zhou H; Wu X; Mao Y; Cui X; Xie B; Liu Z; Cui D; Jiang L; Zhang Q; Xu S, 2017, 'Upregulation of miR-195 accelerates oxidative stress-induced retinal endothelial cell injury by targeting mitofusin 2 in diabetic rats', Molecular and Cellular Endocrinology, vol. 452, pp. 33 - 43, http://dx.doi.org/10.1016/j.mce.2017.05.009
2017
Lee L; Garrett Q; Flanagan JL; Vaddavalli PK; Papas EB, 2016, 'Treatment practices and outcomes of meibomian gland dysfunction at a tertiary center in southern India', Eye and Contact Lens, vol. 44, pp. S138 - S143, http://dx.doi.org/10.1097/ICL.0000000000000356
2016
Hsu KH; De La Jara PL; Ariyavidana A; Watling J; Holden B; Garrett Q; Chauhan A, 2015, 'Release of betaine and dexpanthenol from vitamin E modified silicone-hydrogel contact lenses', Current Eye Research, vol. 40, pp. 267 - 273, http://dx.doi.org/10.3109/02713683.2014.917192
2015
Garrett Q; Willcox MDP, 2015, 'Betaine, osmoprotection, and health of the ocular surface in dry-eye disease', Food and Nutritional Components in Focus, vol. 2015-January, pp. 368 - 389, http://dx.doi.org/10.1039/9781782628446-00368
2015
Veerendranath P; Donovan L; Taneja M; Naduvilath TJ; Garrett Q; Delgado S; Sangwan VS; Ho A, 2014, 'Measurement of consensual accommodation in vision-impaired eyes', Optometry and Vision Science, vol. 91, pp. 752 - 759, http://dx.doi.org/10.1097/OPX.0000000000000294
2014
Bandamwar KL; Papas EB; Garrett Q, 2014, 'Fluorescein staining and physiological state of corneal epithelial cells', Contact Lens and Anterior Eye, vol. 37, pp. 213 - 223, http://dx.doi.org/10.1016/j.clae.2013.11.003
2014
Petznick A; Madigan MC; Garrett Q; Sweeney DF; Evans MD, 2013, 'Contributions of ocular surface components to matrix-metalloproteinases (MMP)-2 and MMP-9 in feline tears following corneal epithelial wounding.', PloS one, vol. 8, http://dx.doi.org/10.1371/journal.pone.0071948
2013
Khandekar N; Willcox MDP; Shih S; Simmons P; Vehige J; Garrett Q, 2013, 'Decrease in hyperosmotic stress-induced corneal epithelial cell apoptosis by L-carnitine', Molecular Vision, vol. 19, pp. 1945 - 1956
2013
Pattamatta U; Willcox M; Stapleton F; Garrett Q, 2013, 'Bovine lactoferrin promotes corneal wound healing and suppresses IL-1 expression in alkali wounded mouse cornea', Current Eye Research, vol. 38, pp. 1110 - 1117, http://dx.doi.org/10.3109/02713683.2013.811259
2013
Garrett Q; Khandekar N; Shih S; Flanagan JL; Simmons P; Vehige J; Willcox MD, 2013, 'Betaine stabilizes cell volume and protects against apoptosis in human corneal epithelial cells under hyperosmotic stress', Experimental Eye Research, vol. 108, pp. 33 - 41, http://dx.doi.org/10.1016/j.exer.2012.12.001
2013
Chen W; Zhang X; Li J; Wang Y; Chen Q; Hou C; Garrett Q, 2013, 'Efficacy of osmoprotectants on prevention and treatment of murine dry eye', Investigative Ophthalmology and Visual Science, vol. 54, pp. 6287 - 6297, http://dx.doi.org/10.1167/iovs.13-12081
2013
Petznick A; Evans MD; Madigan MC; Garrett Q; Sweeney DF, 2012, 'A preliminary study of changes in tear film proteins in the feline eye following nictitating membrane removal', Veterinary Ophthalmology, vol. 15, pp. 164 - 171, http://dx.doi.org/10.1111/j.1463-5224.2011.00955.x
2012
Papas EB; Garrett Q; Bandamwar K, 2012, 'Mechanisms of superficial micropunctate corneal staining with sodium fluorescein', Contact Lens and Anterior Eye, vol. 35, pp. 81 - 84, http://dx.doi.org/10.1016/j.clae.2011.08.008
2012
Hao X; Jeffery J; Wilkie J; Le PT; McFarland G; Johnson G; Mulder R; Garrett Q; Manns F; Nankivil D; Arrieta E; Ho A; Parel J-M; Hughes TM, 2012, 'High refractive index polysiloxane as injectable, in situ curable accommodating intraocular lens', Biomaterials, vol. 33, pp. 5659 - 5671, http://dx.doi.org/10.1016/j.biomaterials.2012.04.052
2012
Petznick A; Evans MDM; Madigan MC; Markoulli M; Garrett Q; Sweeney DF, 2011, 'A comparison of basal and eye-flush tears for the analysis of cat tear proteins', ACTA Ophthalmologica Scandinavica, vol. 89, pp. e75 - e81, http://dx.doi.org/10.1111/j.1755-3768.2010.02082.x
2011
Ashby B; Garrett Q; Willcox MD, 2011, 'Bovine lactoferrin structures promoting corneal epithelial wound healing in vitro', Investigative Ophthalmology and Visual Science, vol. 52, pp. 2719 - 2726, http://dx.doi.org/10.1167/iovs.10-6352
2011
Bandamwar KL; Garrett Q; Papas EB, 2011, '12 Significance of hyper-reflective corneal epithelial cells during confocal microscopy', Contact Lens and Anterior Eye, vol. 34, pp. S19 - S19, http://dx.doi.org/10.1016/s1367-0484(11)60091-x
2011
Bandamwar KL; Garrett Q; Papas EB, 2011, '11 Sodium fluorescein staining of the corneal epithelium: what does it mean at a cellular level?', Contact Lens and Anterior Eye, vol. 34, pp. S19 - S19, http://dx.doi.org/10.1016/s1367-0484(11)60090-8
2011
Papas EB; Bandamwar KL; Chain A; Fang B; Ly MP; Qian M; Garrett Q, 2011, 'Does the observation of solution induced corneal staining signal the presence of corneal inflammation?', Contact Lens and Anterior Eye, vol. 34, pp. S14 - S14, http://dx.doi.org/10.1016/s1367-0484(11)60071-4
2011
Bandamwar KL; Garrett Q; Cheung D; Huang J; Lee L; Ng C; Papas EB, 2010, 'Onset time course of solution induced corneal staining', Contact Lens and Anterior Eye, vol. 33, pp. 199 - 201, http://dx.doi.org/10.1016/j.clae.2010.02.004
2010
Xu S; Flanagan JL; Simmons P; Vehige J; Willcox MD; Garrett Q, 2010, 'Transport of L-carnitine in human corneal and conjunctival epithelial cells', Molecular Vision, vol. 16, pp. 1823 - 1831
2010
Flanagan JL; Simmons P; Vehige J; Willcox MD; Garrett Q, 2010, 'Role of Carnitine in Disease', Nutrition and Metabolism, vol. 7, pp. 30 - 40, http://dx.doi.org/10.1186/1743-7075-7-30
2010
Zhao Z; Carnt N; Aliwarga Y; Wei XM; Naduvilath T; Garrett Q; Korth J; Willcox MD, 2009, 'Care regimen and lens material influence on silicone hydrogel contact lens deposition', Optometry and Vision Science, vol. 86, pp. 251 - 259, http://dx.doi.org/10.1097/OPX.0b013e318196a74b
2009
Pattamatta U; Willcox MD; Stapleton FJ; Cole NA; Garrett Q, 2009, 'Bovine Lactoferrin Stimulates Human Corneal Epithelial Alkali Wound Healing In Vitro', Investigative Ophthalmology and Visual Science, vol. 50, pp. 1636 - 1643, http://dx.doi.org/10.1167/iovs.08-1882
2009
Xu S; Garrett Q; Simmons P; Vehige J; Willcox M, 2008, 'Expression and Localization of Carnitine/Organic Cation Transporter OCTN1 and OCTN2 in Ocular Epithelium', Journal of Proteomics & Bioinformatics, vol. S2, pp. 320 - 321, http://dx.doi.org/10.4172/jpb.s1000229
2008
Pattamatta U; Willcox M; Stapleton F; Garrett Q, 2008, 'Bovine Lactoferrin Promotes Alkali-Induced Wound Healing in Corneal Epithelial Cells by Up-Regulating IL-6 and PDGF', Journal of Proteomics & Bioinformatics, vol. S2, pp. 249 - 250, http://dx.doi.org/10.4172/jpb.s1000180
2008
Garrett Q; Xu S; Simmons P; Vehige J; Xie RZ; Kumar A; Flanagan JL; Zhao Z; Willcox MD, 2008, 'Carboxymethyl cellulose stimulates rabbit corneal epithelial wound healing', Current Eye Research, vol. 33, pp. 567 - 573, http://dx.doi.org/10.1080/02713680802140213
2008
Zhao ZJ; Willcox MD; Aliwarga Y; Carnt N; Garrett Q; wei X, 2008, 'Proteomic analysis of protein deposits on worn daily wear silicone hydrogel contact lenses.', Molecular Vision, vol. 14, pp. 2016 - 2024
2008
Garrett Q; Xu S; Simmons P; Vehige J; Flanagan JL; Willcox MD, 2008, 'Expression and Localization of Carnitine/Organic Cation Transporter OCTN1 and OCTN2 in Ocular Epithelium', Investigative Ophthalmology and Visual Science, vol. 49, pp. 4844 - 4849, http://dx.doi.org/10.1167/iovs.07-1528
2008
Garrett Q; Simmons P; Xu S; Vehige J; Zhao ZJ; Ehrmann K; Willcox MD, 2007, 'Carboxymethylcellulose binds to human corneal epithelial cells and is a modulator of corneal epithelial wound healing', Investigative Ophthalmology and Visual Science, vol. 48, pp. 1559 - 1567, http://dx.doi.org/10.1167/iovs.06-0848
2007
Garrett Q; Khaw PT; Blalock TD; Schultz GS; Grotendorst GR; Daniels JT, 2004, 'Involvement of CTGF in TGF-beta1-stimulation of myofibroblast differentiation and collagen matrix contraction in the presence of mechanical stress.', Invest Ophthalmol Vis Sci, vol. 45, pp. 1109 - 1116, http://dx.doi.org/10.1167/iovs.03-0660
2004
Daniels JT; Cambrey AD; Occleston NL; Garrett Q; Tarnuzzer RW; Schultz GS; Khaw PT, 2003, 'Matrix metalloproteinase inhibition modulates fibroblast-mediated matrix contraction and collagen production in vitro.', Invest Ophthalmol Vis Sci, vol. 44, pp. 1104 - 1110, http://dx.doi.org/10.1167/iovs.02-0412
2003
Daniels JT; Schultz GS; Blalock TD; Garrett Q; Grotendorst GR; Dean NM; Khaw PT, 2003, 'Mediation of transforming growth factor-beta(1)-stimulated matrix contraction by fibroblasts: a role for connective tissue growth factor in contractile scarring.', Am J Pathol, vol. 163, pp. 2043 - 2052, http://dx.doi.org/10.1016/s0002-9440(10)63562-6
2003
Garrett Q; Laycock BG; Garrett RF, 2000, 'Hydrogel lens monomer constituents modulate protein sorption', Investigative Ophthalmology and Visual Science, vol. 41, pp. 1687 - 1695
2000
Garrett Q; Garrett RF; Milthorpe BK, 1999, 'Lysozyme Sorption in Hydrogel Contact Lenses', Investigative Ophthalmology and Visual Science, vol. 40, pp. 897 - 903
1999
Garrett Q; Griesser HJ; Milthorpe BK; Garrett RF, 1999, 'Irreversible adsorption of human serum albumin to hydrogel lenses: A study using electron spin resonance spectroscopy', Biomaterials, vol. 20, pp. 1345 - 1356, http://dx.doi.org/10.1016/S0142-9612(99)00037-X
1999
Garrett Q; Chatelier RC; Griesser HJ; Milthorpe BK, 1998, 'Effect of charged groups on the adsorption and penetration of proteins onto and into carboxymethylated poly(HEMA) hydrogels', Biomaterials, vol. 19, pp. 2175 - 2186, http://dx.doi.org/10.1016/S0142-9612(98)00125-2
1998
Garrett Q; Milthorpe BK, 1996, 'Human serum albumin adsorption on hydrogel contact lenses in vitro', Investigative Ophthalmology and Visual Science, vol. 37, pp. 2594 - 2602
1996
Book Chapters
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Stapleton, F; Garrett Q; Chan C; Craig J, 2015, 'The Epidemiology of Dry Eye 2 Disease', in Dry Eye A Practical Approach, Springer, pp. 21 - 29
2015
Garrett Q; Willcox M, 2015, 'Betaine, Osmoprotection, and Health of the Ocular Surface in Dry Eye Disease', in Betaine Chemistry, Analysis, Function and Effects, Royal Society of Chemistry, http://dx.doi.org/10.1039/9781782628446
2015
Conference Papers
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Mohamed A; Sangwan V; Kumar A; Garrett Q; Parel J-M; Augusteyn R; Asafali AM, 2010, 'Lens Growth in the Indian Population', in Lens Growth in the Indian Population, ARVO 2010 Annual Meeting, Fort Lauderdale, Florida, USA, presented at ARVO 2010 Annual Meeting, Fort Lauderdale, Florida, USA, 02 May 2010 - 06 May 2010
2010
Papas EB; Petznick A; Stapleton FJ; Garrett Q, 2006, 'Involvement of Matrixmetalloproteinase-9 (MMP-9) and Tissue Inhibitor of Matrixmetalloproteinase-1 (TIMP-1) During Orthokeratology', in Frank R (ed.), ARVO 2006 Annual Meeting, ARVO 2006: Association for Research in Vision and Ophthalmology, Fort Lauderdale, Florida, pp. 117 - 117, presented at ARVO 2006: Association for Research in Vision and Ophthalmology, Fort Lauderdale, Florida, -
2006
Willcox MD; Khan S; Zhao ZJ; Garrett Q, 2005, 'The binding of CMC to human corneal epithelial cells and effect on cell migration/proliferation', in Optometry and Vision Science, Lippincott Williams & Wilkins, Philadelphia, PA, presented at 82: E-Abstract 050032 American Academy of Optometry, San Diego, Californa, USA, -
2005
Aristoteli LP; Willcox MD; Garrett Q, 1999, 'The interaction of mucin with an ocular strain of P aeruginosa: An insight into degradation', in IXth International Congress of Bacteriology and Applied Microbiology, IXth International Congress of Bacteriology and Applied Microbiology, Sydney, presented at IXth International Congress of Bacteriology and Applied Microbiology, Sydney, 16 August 1999 - 20 August 1999
1999
Chatelier RC; Griesser HJ; Milthorpe BK; Garrett Q, 1998, 'The irreversible adsorption of human serum albumin on hydrogel contact lenses: Comparison between experimental data and a model for adsorption kinetics', in Optometry and Vision Science, Lippincott Williams & Wilkins, Philadelphia, PA, pp. 45 - 45, presented at American Academy of Optometry (1998), Sydney, 28 March 1998 - 30 March 1998
1998
Garrett Q; Chatelier R; Griesser H; Milthorpe BK, 1996, 'Irreversible binding of protein on poly(HEMA)-based hydrogel contact lenses and carboxymethyl-poly(HEMA) hydrogel discs', in Transactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium, pp. 494
1996
Garrett Q; Chatelier R; Griesser H; Milthorpe BK, 1996, 'Kinetics of irreversible binding of protein on hydrogel contact lenses', in Transactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium, pp. 524
1996