Phoebe Phillips

Associate Professor

Research Interests: Pancreatic cancer is a devastating disease with a dismal prognosis. The five-year survival rate is less than 5% and most patients die within a few months of diagnosis. My current research focuses on identifying novel therapeutic approaches for pancreatic cancer including targeting the extensive scarring (fibrosis) which we have shown enhances pancreatic cancer progression.

Broad Research Areas:
Cancer, Inflammation, Cell Biology and Gene Regulation

Society Memberships & Professional Activities:
American Pancreatic Association, European Pancreatic Association, Australasian Pancreatic Club (Honorary Secretary, www.pancreas.org.au), Gastroenterological Society of Australia, American Association of Cancer Research, Australian Health and Medical Research Council

Specific Research Keywords:
Cancer, Pancreatic cancer, Pancreatic stellate cells, Drug Resistance, Apoptosis

PUBLICATIONS

Journal articles
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Kokkinos J; Ignacio RMC; Sharbeen G; Boyer C; Gonzales-Aloy E; Goldstein D; McCarroll JA; Phillips PA, 2020, 'Targeting the undruggable in pancreatic cancer using nano-based gene silencing drugs', Biomaterials, vol. 240, pp. 119742, http://dx.doi.org/10.1016/j.biomaterials.2019.119742
2020
Tjandra KC; McCarthy N; Yang L; Laos AJ; Sharbeen G; Phillips PA; Forgham H; Sagnella SM; Whan RM; Kavallaris M; Thordarson P; McCarroll JA, 2019, 'Identification of Novel Medulloblastoma Cell-Targeting Peptides for Use in Selective Chemotherapy Drug Delivery', Journal of Medicinal Chemistry, http://dx.doi.org/10.1021/acs.jmedchem.9b00851
2019
Vennin C; Mélénec P; Rouet R; Nobis M; Cazet AS; Murphy KJ; Herrmann D; Reed DA; Lucas MC; Warren SC; Elgundi Z; Pinese M; Kalna G; Roden D; Samuel M; Zaratzian A; Grey ST; Da Silva A; Leung W; Johns AL; Chantrill LA; Chou A; Steinmann A; Arshi M; Dwarte T; Froio D; Pereira B; Ritchie S; Chambers CR; Metcalf X; Waddell N; Pearson JV; Patch AM; Nones K; Newell F; Mukhopadhyay P; Addala V; Kazakoff S; Holmes O; Leonard C; Wood S; Grimmond SM; Hofmann O; Christ A; Bruxner T; Samra JS; Pavlakis N; High HA; Asghari R; Merrett ND; Pavey D; Das A; Cosman PH; Ismail K; O’Connnor C; Stoita A; Williams D; Spigellman A; Lam VW; McLeod D; Kirk J; Kench JG; Grimison P; Cooper CL; Sandroussi C; Goodwin A; Mead RS; Tucker K; Andrews L; Texler M; Forest C; Epari KP; Ballal M; Fletcher DR; Mukhedkar S; Zeps N; Beilin M; Feeney K; Nguyen NQ; Ruszkiewicz AR; Worthley C; Chen J; Brooke-Smith ME; Papangelis V; Clouston AD; Barbour AP; O’Rourke TJ; Fawcett JW; Slater K; Hatzifotis M; Hodgkinson P; Nikfarjam M; Eshleman JR; Hruban RH; Wolfgang CL; Lawlor RT; Beghelli S; Corbo V; Scardoni M; Bassi C, 2019, 'CAF hierarchy driven by pancreatic cancer cell p53-status creates a pro-metastatic and chemoresistant environment via perlecan', Nature Communications, vol. 10, pp. 3637, http://dx.doi.org/10.1038/s41467-019-10968-6
2019
Pinho AV; Van Bulck M; Chantrill L; Arshi M; Sklyarova T; Herrmann D; Vennin C; Gallego-Ortega D; Mawson A; Giry-Laterriere M; Magenau A; Leuckx G; Baeyens L; Gill AJ; Phillips P; Timpson P; Biankin AV; Wu J; Rooman I, 2018, 'ROBO2 is a stroma suppressor gene in the pancreas and acts via TGF-β signalling', Nature Communications, vol. 9, pp. 5083, http://dx.doi.org/10.1038/s41467-018-07497-z
2018
Yeo D; Phillips P; Baldwin GS; He H; Nikfarjam M, 2017, 'Inhibition of group 1 p21-activated kinases suppresses pancreatic stellate cell activation and increases survival of mice with pancreatic cancer', International Journal of Cancer, vol. 140, pp. 2101 - 2111, http://dx.doi.org/10.1002/ijc.30615
2017
Sharbeen G; Youkhana J; Mawson A; McCarroll J; Nunez A; Biankin A; Johns A; Goldstein D; Phillips P, 2017, 'MutY-Homolog (MYH) inhibition reduces pancreatic cancer cell growth and increases chemosensitivity', Oncotarget, vol. 8, pp. 9216 - 9229, http://dx.doi.org/10.18632/oncotarget.13985
2017
Akerman A; Vennin C; Sharbeen G; Warren SC; Timpson P; Phillips PA, 2016, 'Novel therapeutics and preclinical imaging for pancreatic cancer - View from the lab', Cancer Forum, vol. 40, pp. 16 - 22
2016
McCarroll JA; Teo J; Boyer C; Youkhana J; Sagnella S; Duong H; Sharbeen G; Goldstein D; Davis T; Kavallaris M; Phillips P; Liu J, 2016, 'A rationally optimized nanoparticle system for the delivery of RNA interference therapeutics into pancreatic tumors in vivo.', Biomacromolecules, vol. 17, pp. 2337 - 2351, http://dx.doi.org/10.1021/acs.biomac.6b00185
2016
Sharbeen G; McCarroll J; Liu J; Youkhana J; Limbri LF; Biankin AV; Johns A; Kavallaris M; Goldstein D; Phillips PA, 2016, 'Delineating the Role of βIV-Tubulins in Pancreatic Cancer: βIVb-Tubulin Inhibition Sensitizes Pancreatic Cancer Cells to Vinca Alkaloids', Neoplasia (United States), vol. 18, pp. 753 - 764, http://dx.doi.org/10.1016/j.neo.2016.10.011
2016
Glass JJ; Phillips PA; Gunning PW; Stehn JR, 2015, 'Hypoxia alters the recruitment of tropomyosins into the actin stress fibres of neuroblastoma cells', BMC Cancer, vol. 15, http://dx.doi.org/10.1186/s12885-015-1741-8
2015
Vuong QV; Hirun S; Chuen TLK; Goldsmith CD; Murchie S; Bowyer MC; Phillips PA; Scarlett CJ, 2015, 'Antioxidant and anticancer capacity of saponin-enriched Carica papaya leaf extracts', International Journal of Food Science and Technology, vol. 50, pp. 169 - 177, http://dx.doi.org/10.1111/ijfs.12618
2015
Sharbeen G; McCarroll J; Goldstein D; Phillips PA, 2015, 'Exploiting Base Excision Repair to Improve Therapeutic Approaches for Pancreatic Cancer', Frontiers in Nutrition, vol. 2, pp. 10, http://dx.doi.org/10.3389/fnut.2015.00010
2015
McCarroll JA; Sharbeen G; Liu J; Youkhana J; Goldstein D; McCarthy N; Limbri LF; Dischl D; Ceyhan GO; Erkan M; Johns AL; Biankin AV; Kavallaris M; Phillips PA, 2015, 'βIII-Tubulin: A novel mediator of chemoresistance and metastases in pancreatic cancer', Oncotarget, vol. 6, pp. 2235 - 2249, http://dx.doi.org/10.18632/oncotarget.2946
2015
Vuong QV; Hirun S; Chuen TLK; Goldsmith CD; Munro B; Bowyer MC; Chalmers AC; Sakoff JA; Phillips PA; Scarlett CJ, 2015, 'Physicochemical, antioxidant and anti-cancer activity of a Eucalyptus robusta (Sm.) leaf aqueous extract', Industrial Crops and Products, vol. 64, pp. 167 - 174, http://dx.doi.org/10.1016/j.indcrop.2014.10.061
2015
McCarroll JA; Dwarte T; Baigude H; Dang J; Yang L; Erlich RB; Kimpton K; Teo J; Sagnella SM; Akerfeldt MC; Liu J; Phillips PA; Rana TM; Kavallaris M, 2015, 'Therapeutic targeting of polo-like kinase 1 using RNA-interfering nanoparticles (iNOPs) for the treatment of non-small cell lung cancer', Oncotarget, vol. 6, pp. 12020 - 12034, http://dx.doi.org/10.18632/oncotarget.2664
2015
Byrne FL; Yang L; Phillips PA; Hansford LM; Fletcher JI; Ormandy CJ; McCarroll JA; Kavallaris M, 2014, 'RNAi-mediated stathmin suppression reduces lung metastasis in an orthotopic neuroblastoma mouse model', Oncogene, vol. 33, pp. 882 - 890, http://dx.doi.org/10.1038/onc.2013.11
2014
Luo AS; Lim A; Jung HJ; Phillips PA; Grimm MC, 2014, 'Retinoic acid is required for the generation of protective appendiceal regulatory T cells', JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, vol. 29, pp. 20 - 20, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000343863000041&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2014
McCarroll JA; Naim S; Sharbeen G; Russia N; Lee J; Kavallaris M; Goldstein D; Phillips PA, 2014, 'Role of pancreatic stellate cells in chemoresistance in pancreatic cancer', Frontiers in Physiology, vol. 5 APR, http://dx.doi.org/10.3389/fphys.2014.00141
2014
McCarroll J; Teo J; Boyer C; Goldstein D; Kavallaris M; Phillips PA, 2014, 'Potential applications of nanotechnology for the diagnosis and treatment of pancreatic cancer', Frontiers in Physiology, vol. 5, pp. 1 - 10, http://dx.doi.org/10.3389/fphys.2014.00002
2014
Vuong QV; Hirun S; Phillips PA; Chuen TLK; Bowyer MC; Goldsmith CD; Scarlett CJ, 2014, 'Fruit-derived phenolic compounds and pancreatic cancer: Perspectives from Australian native fruits', Journal of Ethnopharmacology, vol. 152, pp. 227 - 242, http://dx.doi.org/10.1016/j.jep.2013.12.023
2014
Vuong QV; Hirun S; Chuen TLK; Goldsmith CD; Bowyer MC; Chalmers AC; Phillips PA; Scarlett CJ, 2014, 'Physicochemical composition, antioxidant and anti-proliferative capacity of a lilly pilly (Syzygium paniculatum) extract', Journal of Herbal Medicine, vol. 4, pp. 134 - 140, http://dx.doi.org/10.1016/j.hermed.2014.04.003
2014
Sheahan AV; Phillips PA; Khachigian LM, 2013, 'Therapeutic perspectives on pancreatic cancer', Current Cancer Drug Targets, vol. 13, pp. 400 - 410, http://dx.doi.org/10.2174/1568009611313040004
2013
Barrera L; Oldfield F; Nunes Q; Campbell F; Lane B; Andrews T; Phillips P; Greenhalf W; Neoptolemos J; Costello E, 2013, 'Isolation of Quiescent and Activated Human Pancreatic Stellate Cells for MicroRNA Profiling', PANCREAS, vol. 42, pp. 1339 - 1339, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000330468400040&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2013
Teo J; Erlich RB; Sagnella S; Dwarte T; Davis TP; Kavallaris M; McCarroll J; Boyer C; Duong HTT; Phillips P; Sharbeen G; Goldstein D, 2013, 'Effective delivery of siRNA into cancer cells and tumors using well-defined biodegradable cationic star polymers', Molecular Pharmaceutics, vol. 10, pp. 2435 - 2444, http://dx.doi.org/10.1021/mp400049e
2013
Vuong QV; Hirun S; Chuen TLK; Goldsmith CD; Bowyer MC; Scarlett CJ; Chalmers AC; Phillips PA, 2013, 'Physicochemical composition, antioxidant and anti-proliferative capacity of a lilly pilly (Syzygium paniculatum) extract', Journal of Herbal Medicine, http://dx.doi.org/10.1016/j.hermed.2014.04.003
2013
Luo AS; Jung HJ; Phillips PA; Grimm MC, 2013, 'The mechanisms of regulatory T cell expansion following appendicitis induction', JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, vol. 28, pp. 11 - 11, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000324106900019&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2013
Vuong QV; Hirun S; Roach PD; Bowyer MC; Phillips PA; Scarlett CJ, 2013, 'Effect of extraction conditions on total phenolic compounds and antioxidant activities of Carica papaya leaf aqueous extracts', Journal of Herbal Medicine, vol. 3, pp. 104 - 111, http://dx.doi.org/10.1016/j.hermed.2013.04.004
2013
Erkan M; Adler G; Apte MV; Bachem MG; Buchholz M; Detlefsen S; Esposito I; Friess H; Gress TM; Habisch HJ; Hwang RN; Jaster R; Kleeff JH; Kloppel G; Kordes C; Logsdon CD; Masamune A; Michalski CW; Oh J; Pinzani M; Reiser-erkan C; Tsukamoto H; Wilson JS, 2012, 'StellaTUM: current consensus and discussion on pancreatic stellate cell research', Gut, vol. 61, pp. 172 - 178, http://dx.doi.org/10.1136/gutjnl-2011-301220
2012
Vonlaufen A; Phillips PA; Xu ; Zhang X; Yang L; Pirola R; Wilson JS; Apte MV, 2011, 'Withdrawal of alcohol promotes regression while continued alcohol intake promotes persistence of LPS-induced pancreatic injury in alcohol-fed rats', Gut, vol. 60, pp. 238 - 246, http://dx.doi.org/10.1136/gut.2010.211250
2011
Barreto SG; Jardine D; Phillips P; Bhatia M; Saccone GTP, 2011, 'Reply', Pancreas, vol. 40, pp. 1144 - 1145, http://dx.doi.org/10.1097/MPA.0b013e31822b88b2
2011
Arun SJ; Xu Z; Fiala-Beer E; Phillips P; Goldstein D; Biankin A; Pirola R; Wilson JS; Apte MV, 2011, 'Hepatocyte growth factor: a potential therapeutic target in pancreatic cancer', CANCER RESEARCH, vol. 71, http://dx.doi.org/10.1158/1538-7445.AM2011-LB-395
2011
Yang L; Phillips PA; Xu Z; Youkhana J; Vonlaufen A; Pirola R; Wilson J; Apte MV, 2010, 'Collagen-I increases the expression of transgelin and lumican (regulators of cell migration) by activated pancreatic stellate cells', JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, vol. 25, pp. A14 - A15, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000283321200036&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2010
Barreto SG; Jardine D; Phillips P; Bhatia M; Saccone GTP, 2010, 'Can by-products in country-made alcohols induce acute pancreatitis?', Pancreas, vol. 39, pp. 1199 - 1204, http://dx.doi.org/10.1097/MPA.0b013e3181dd65b5
2010
Seth D; D'Souza el-Guindy NB; Apte MV; Mari M; Dooley S; Neumann M; Haber P; Kundu S; Darwanto A; De villiers WJ; Vonlaufen A; Xu Z; Phillips P; Yang S; Goldstein D; Pirola RM; Wilson JS; Moles A; Fernandez A; Colell A; Garcia-ruiz C; Fernandez-checa JC; Meyer C; Meindl-beinker N, 2010, 'Alcohol, signaling, and ECM turnover', Alcoholism : Clinical and Experimental Research, vol. 34, pp. 4 - 18, http://dx.doi.org/10.1111/j.1530-0277.2009.01060.x
2010
Phillips PA; Yang L; Shulkes A; Vonlaufen A; Poljak A; Bustamante S; Warren A; Xu ; Guilhaus M; Pirola R; Apte MV; Wilson JS, 2010, 'Pancreatic stellate cells produce acetylcholine and may play a role in pancreatic exocrine secretion', Proceedings of the National Academy of Sciences of the United States of America, vol. 107, pp. 17397 - 17402, http://dx.doi.org/10.1073/pnas.1000359107
2010
Yang L; Phillips PA; Xu Z; Youkhana J; Vonlaufen A; Pirola R; Wilson J; Apte MV, 2010, 'Collagen-I Increases the Expression of Transgelin and Lumican (Regulators of Cell Migration) by Activated Pancreatic Stellate Cells', PANCREAS, vol. 39, pp. 1358 - 1359, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000282946600262&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2010
Vonlaufen A; Phillips PA; Yang L; Xu Z; Fiala-Beer E; Zhang X; Pirola R; Wilson JS; Apte MV, 2010, 'Isolation of Quiescent Human Pancreatic Stellate Cells: A Promising in vitro Tool for Studies of Human Pancreatic Stellate Cell Biology', Pancreatology, vol. 10, pp. 434 - 443, http://dx.doi.org/10.1159/000260900
2010
Phillips P; Yang L; Vonlaufen A; Xu Z; Biankin A; Goldstein D; Pirola R; Wilson J; Apte M, 2009, 'Heat shock proteins are induced during pancreatic stellate cell activation in pancreatic cancer', CANCER RESEARCH, vol. 69, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000209702804197&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2009
Phillips P; Chow MW; Vonlaufen A; Xu Z; Yang L; Biankin A; Goldstein D; Pirola R; Wilson J; Apte M, 2009, 'Gene expression profiling of human pancreatic stellate cells and their roles in pancreatic cancer progression.', CANCER RESEARCH, vol. 69, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000209702804198&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2009
Sharif R; Dawra R; Wasiluk K; Phillips P; Dudeja V; Kurt-Jones E; Finberg R; Saluja A, 2009, 'Impact of toll-like receptor 4 on the severity of acute pancreatitis and pancreatitis-associated lung injury in mice', GUT, vol. 58, pp. 813 - 819, http://dx.doi.org/10.1136/gut.2008.170423
2009
Dudeja V; Mujumdar N; Phillips P; Chugh R; Borja-Cacho D; Dawra RK; Vickers SM; Saluja AK, 2009, 'Heat Shock Protein 70 Inhibits Apoptosis in Cancer Cells Through Simultaneous and Independent Mechanisms', GASTROENTEROLOGY, vol. 136, pp. 1772 - 1782, http://dx.doi.org/10.1053/j.gastro.2009.01.070
2009
Phillips PA; Yang L; Poljak A; Bustamante S; Shulkes A; Vonlaufen A; Xu Z; Pirola R; Apte M; Wilson J, 2009, 'Pancreatic stellate cells synthesise and secrete acetylcholine: a potential role in enzyme secretion', JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, vol. 24, pp. A335 - A335, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000270551200307&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2009
Xu Z; Phillips PA; Vonlaufen A; Fiala-Beer E; Yang L; Biankin A; Goldstein D; Pirola R; Wilson J; Apte M, 2009, 'Normal Pancreatic Stellate Cells Facilitate Pancreatic Cancer Progression, Exhibit Transendothelial Migration and Accompany Cancer Cells to Distant Metastatic Sites', PANCREAS, vol. 38, pp. 1062 - 1062, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000271225300403&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2009
Phillips PA; Yang L; Poljak A; Bustamante S; Shulkes A; Vonlaufen A; Xu Z; Guilhaus M; Pirola R; Apte M; Wilson J, 2009, 'Pancreatic Stellate Cells Stimulate Acinar Enzyme Secretion Via the Production of Acetylcholine', PANCREAS, vol. 38, pp. 1038 - 1039, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000271225300294&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2009
Dawra R; Ku YS; Sharif R; Dhaulakhandi D; Phillips P; Dudeja V; Saluja AK, 2008, 'An improved method for extracting myeloperoxidase and determining its activity in the pancreas and lungs during pancreatitis', PANCREAS, vol. 37, pp. 62 - 68, http://dx.doi.org/10.1097/MPA.0b013e3181607761
2008
Vonlaufen A; Phillips PA; Xu ZH; Goldstein D; Pirola RC; Wilson JS; Apte MV, 2008, 'Pancreatic stellate cells and pancreatic cancer cells: An unholy alliance', Cancer research, vol. 68, pp. 7707 - 7710, http://dx.doi.org/10.1158/0008-5472.CAN-08-1132
2008
Vonlaufen A; Joshi SB; Qu CF; Phillips PA; Xu ZH; Parker N; Toi C; Pirola RC; Wilson JS; Goldstein D; Apte MV, 2008, 'Pancreatic stellate cells: Partners in crime with pancreatic cancer cells', Cancer Research, vol. 68, pp. 2085 - 2093, http://dx.doi.org/10.1158/0008-5472.CAN-07-2477
2008
Saluja AK; Lerch MM; Phillips PA; Dudeja V, 2007, 'Why does pancreatic overstimulation cause pancreatitis?', ANNUAL REVIEW OF PHYSIOLOGY, vol. 69, pp. 249 - 269, http://dx.doi.org/10.1146/annurev.physiol.69.031905.161253
2007
Aghdassi A; Phillips P; Dudeja V; Dhaulakhandi D; Sharif R; Dawra R; Lerch MM; Saluja A, 2007, 'Heat shock protein 70 increases tumorigenicity and inhibits apoptosis in pancreatic adenocarcinoma', CANCER RESEARCH, vol. 67, pp. 616 - 625, http://dx.doi.org/10.1158/0008-5472.CAN-06-1567
2007
Dawra R; Sharif R; Phillips P; Dudeja V; Dhaulakhandi D; Saluja AK, 2007, 'Development of a new mouse model of acute pancreatitis induced by administration of L-arginine', AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, vol. 292, pp. G1009 - G1018, http://dx.doi.org/10.1152/ajpgi.00167.2006
2007
Phillips PA; Dudeja V; McCarroll JA; Borja-Cacho D; Dawra RK; Grizzle WE; Vickers SM; Saluja AK, 2007, 'Triptolide induces pancreatic cancer cell death via inhibition of heat shock protein 70', Cancer Research, vol. 67, pp. 9407 - 9416, http://dx.doi.org/10.1158/0008-5472.CAN-07-1077
2007
Mccarroll JA; Phillips PA; Santucci N; Pirola RC; Wilson JS; Apte MV, 2006, 'Vitamin A inhibits pancreatic stellate cell activation: implications for treatment of pancreatic fibrosis', Gut, vol. 55, pp. 79 - 89, http://dx.doi.org/10.1136/gut.2005.064543
2006
Mccarroll JA; Phillips PA; Kumar RK; Park S; Pirola RC; Wilson JS; Apte MV, 2004, 'Pancreatic stellate cell migration: role of the phosphatidyl inositol 3-kinase (PI3-kinase) pathway', Biochemical Pharmacology, vol. 67, pp. 1215 - 1225, http://dx.doi.org/10.1016/j.bcp.2003.11.013
2004
Phillips PA; Wu MJ; Kumar RK; Doherty E; Mccarroll JA; Park S; Pirola RC; Wilson JS; Apte MV, 2003, 'Cell migration: A novel aspect of pancreatic stellate cell biology', Gut, vol. 52, pp. 677 - 682, http://dx.doi.org/10.1136/gut.52.5.677
2003
Mccarroll JA; Phillips PA; Park S; Doherty E; Pirola RC; Wilson JS; Apte MV, 2003, 'Pancreatic stellate cell activation by ethanol and acetaldehyde: is it mediated by the mitogen-activated protein kinase signaling pathway?', Pancreas, vol. 27, pp. 150 - 160, http://dx.doi.org/10.1097/00006676-200308000-00008
2003
Phillips PA; Mccarroll JA; Park S; Wu MJ; Korsten MA; Pirola RC; Wilson JS; Apte MV, 2003, 'Rat pancreatic stellate cells secret matrix matalloproteinases - implications for extracellular matrix turnover', Gut, vol. 52, pp. 275 - 282, http://dx.doi.org/10.1136/gut.52.2.275
2003
Mews PJ; Phillips PA; Fahmy R; Korsten MA; Pirola RC; Wilson JS; Apte MV, 2002, 'Pancreatic stellate cells respond to inflammatory cytokines: potential role in chronic pancratitis', Gut, vol. 50, pp. 535 - 541, http://dx.doi.org/10.1136/gut.50.4.535
2002
Phillips P; Thomson M, 2002, 'Small GTP-binding proteins in the nuclei of human placenta', JOURNAL OF CELLULAR BIOCHEMISTRY, vol. 84, pp. 100 - 107, http://dx.doi.org/10.1002/jcb.1269
2002
Apte MV; Phillips PA; Fahmy R; Darby SL; Rodgers SC; Mccaughan GW; Korsten MA; Pirola RC; Naidoo D; Wilson JS, 2000, 'Does alcohol directly stimulate pancreatic fibrogenesis? Studies with rat pancreatic stellate cells', Gastroenterology, vol. 118, pp. 780 - 794, http://dx.doi.org/10.1016/S0016-5085(00)70148-X
2000
O Callaghan CJ; Phillips PA; Krum H; Howes LG, 1995, 'The effects of short term alcohol intake on clinic and ambulatory blood pressure in normotensive `social` drinkers', American Journal of Hypertension, vol. 8, pp. 572 - 577, http://dx.doi.org/10.1016/0895-7061(95)00041-M
1995
Book Chapters
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McCarroll JA; Sharbeen G; Kavallaris M; Phillips PA, 2019, 'The use of star polymer nanoparticles for the delivery of siRNA to mouse orthotopic pancreatic tumor models', in Methods in Molecular Biology, United States, pp. 329 - 353, http://dx.doi.org/10.1007/978-1-4939-9220-1_23
2019
Sharbeen G; McAlpine SR; Phillips P, 2015, 'HSP47: The New Heat Shock Protein Therapeutic Target', in Topics in Medicinal Chemistry, Springer Berlin Heidelberg, pp. 197 - 220, http://dx.doi.org/10.1007/7355_2015_89
2015
Erlich RB; Kavallaris M; McCarroll J; Phillips P, 2013, 'Nanotechnology, tumour biomarkers and RNA interference for personalized medicine applications', in Shiddiky MJA; Wee EJH; Rauf S; Trau M (ed.), Microfluidics, Nanotechnology and Disease Biomarkers for Personalized Medicine Applications, Nova Science Publishers, pp. 167 - 187
2013
Conference Abstracts
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Sharbeen G; Akerman A; McCarroll J; Boyer C; Holst J; Youkhana J; Davis TP; Goldstein D; Erkan M; Phillips PA, 2018, 'Metabolically Reprograming Pancreatic Stellate Cells Using a Novel Nanomedicine for the Treatment of Pancreatic Cancer', in PANCREAS, LIPPINCOTT WILLIAMS & WILKINS, Vol. 47, pp. 1422 - 1422, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000449304600230&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2018
Kokkinos J; Sharbeen G; McCarroll J; Boyer C; Akerman A; Youkhana J; Davis TP; Goldstein D; Phillips PA, 2018, 'beta III-Tubulin is a Brake for External Cell-Death Signaling and Regulates TRAIL Sensitivity in Pancreatic Cancer', in PANCREAS, LIPPINCOTT WILLIAMS & WILKINS, Miami Beach, Florida, Vol. 47, pp. 1401 - 1401, presented at 49th Annual Meeting of the American Pancreatic Association, Miami Beach, Florida, 31 October 2018 - 03 November 2018, http://dx.doi.org/10.1097/MPA.0000000000001177
2018
Pinho AV; Bulck MV; Chantrill L; Arshi M; Sklyarova T; Herrmann D; Vennin C; Gallego-Ortega D; Mawson A; Giry-Laterriere M; Magenau A; Baeyens L; Gill AJ; Phillips P; Timpson P; Biankin AV; Wu J; Rooman I, 2018, 'ROBO2 is a Stroma Suppressor Gene in the Pancreas Through Regulation of TGF-beta', in PANCREAS, LIPPINCOTT WILLIAMS & WILKINS, Vol. 47, pp. 1417 - 1417, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000449304600212&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2018
Sharbeen G; Youkhana J; Mawson A; Mccarroll J; Goldstein D; Phillips P, 2016, 'MutY-homolog modulates pancreatic cancer cell survival and chemoresistance', in JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, WILEY-BLACKWELL, Vol. 31, pp. 60 - 60, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000384664700111&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2016
Phillips P; Sharbeen G; Youkhana J; Mawson A; McCarroll J; Akerman A; Goldstein D, 2016, 'MutY-Homolog Modulates Pancreatic Cancer Cell Survival and Chemoresistance', in PANCREAS, LIPPINCOTT WILLIAMS & WILKINS, Vol. 45, pp. 1534 - 1534, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000386978400183&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2016
Boyer C; Teo J; Phillips P; Erlich RB; Sagnella S; Sharbeen G; Dwarte T; Duong HTT; Goldstein D; Davis TP; Kavallaris M; McCarroll J, 2015, 'Correction to "effective delivery of siRNA into cancer cells and tumors using well-defined biodegradable cationic star polymers"', in Molecular Pharmaceutics, Vol. 12, pp. 1004, http://dx.doi.org/10.1021/acs.molpharmaceut.5b00092
2015
Sharbeen G; McCarroll J; Liu J; Youkhana J; Goldstein D; Kavallaris M; Phillips P, 2015, 'beta III-Tubulin Regulates Sensitivity to Nab-Paclitaxel (Abraxane (R)) in Pancreatic Cancer', in PANCREAS, LIPPINCOTT WILLIAMS & WILKINS, Vol. 44, pp. 1414 - 1415, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000363324000260&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2015
Sharbeen G; Liu J; McCarroll J; Limbri L; Youkhana J; Goldstein D; Kavallaris M; Phillips P, 2015, 'beta IVb-Tubulin is a Novel Therapeutic Target for the Treatment of Pancreatic Cancer', in PANCREAS, LIPPINCOTT WILLIAMS & WILKINS, Vol. 44, pp. 1414 - 1414, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000363324000259&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2015
Barrera L; Lane B; Brumskill S; Oldfield F; Nunes Q; Campbell F; Andrews T; Phillips P; Halloran C; Greenhalf W; Neoptolemos J; Costello E, 2015, 'Pancreatic Human Fibroblast Expression Profiling Reveals Novel microRNAs and mRNAs in the Diseased Pancreas', in PANCREAS, LIPPINCOTT WILLIAMS & WILKINS, Vol. 44, pp. 1361 - 1362, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000363324000043&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2015
Byrne FL; Phillips PA; Hansford LM; Fletcher JI; Ormandy CJ; McCarroll JA; Kavallaris M, 2012, 'Stathmin suppression influences ROCK signaling and reduces cell invasion and metastasis in neuroblastoma', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Vol. 72, http://dx.doi.org/10.1158/1538-7445.AM2012-1444
2012
Liu J; McCarroll J; Apte MV; Youkhana J; Kavallaris M; Phillips PA, 2010, 'Beta III- and beta IVb-tubulin mediate sensitivity to chemotherapeutic drugs in pancreatic cancer cells', in JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, WILEY-BLACKWELL PUBLISHING, INC, Vol. 25, pp. A76 - A76, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000283321200206&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2010
Liu J; McCarroll J; Apte MV; Youkhana J; Kavallaris M; Phillips PA, 2010, 'Beta III- and Beta IVB-Tubulin Mediate Sensitivity to Chemotherapeutic Drugs in Pancreatic Cancer Cells', in PANCREAS, LIPPINCOTT WILLIAMS & WILKINS, Vol. 39, pp. 1330 - 1330, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000282946600138&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2010
Conference Papers
add
Youkhana J; Mccarroll J; Sharbeen G; Erkan M; Liu J; Goldstein D; Phillips PA, 2014, 'Heat shock protein 47 is a potential therapeutic target for the depletion of cancer-promoting stromal cells in pancreatic cancer', in JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, WILEY-BLACKWELL, pp. 7 - 7, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000343863000015&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2014
Teo J; Boyer C; Sharbeen G; Sagnella S; Liu J; Youkhana J; Duong HT; Goldstein D; Davis TP; Kavallaris M; McCarroll J; Phillips PA, 2014, 'Design and Synthesis of Novel PEGylated Star Nanoparticles as Delivery Agents for Short-Interfering RNA (siRNA) to Pancreatic Cancer Cells', in PANCREAS, LIPPINCOTT WILLIAMS & WILKINS, pp. 1416 - 1416, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000344362600356&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2014
Sharbeen G; Liu J; Mccarroll J; Youkhana J; Teo J; Mccarthy N; Goldstein D; Kavallaris M; Phillips PA, 2013, 'beta III-tubulin is a novel therapeutic target for the treatment of pancreatic cancer', in JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, WILEY-BLACKWELL, pp. 12 - 12, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000324106900022&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2013
Sharbeen G; Liu J; McCarroll J; Youkhana J; Teo J; McCarthy N; Goldstein D; Kavallaris M; Phillips PA, 2013, 'beta III-Tubulin is a Novel Therapeutic Target for the Treatment of Pancreatic Cancer', in PANCREAS, LIPPINCOTT WILLIAMS & WILKINS, pp. 1381 - 1381, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000330468400204&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2013
Teo J; Boyer C; Liu J; Sharbeen G; Erlich R; Youkhana J; Duong HT; Goldstein D; Davis TP; Kavallaris M; McCarroll J; Phillips PA, 2013, 'Inhibition of beta III-Tubulin Using a Novel Nanoparticle-siRNA Approach Sensitizes Pancreatic Cancer Cells to Chemotherapy', in PANCREAS, LIPPINCOTT WILLIAMS & WILKINS, pp. 1385 - 1385, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000330468400222&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2013
Youkhana J; Liu J; Kiriella N; Yang L; Xu Z; Biankin A; Goldstein D; Pirola R; Wilson J; Apte MV; Phillips PA, 2011, 'Heat Shock Proteins 27 and 47 Inhibit Platelet-Derived Growth Factor (PDGF)-Induced Pancreatic Stellate Cell Proliferation: Implication in Pancreatic Cancer Progression', in PANCREAS, LIPPINCOTT WILLIAMS & WILKINS, pp. 1365 - 1366, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000296398000273&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2011
Arun SJ; Xu Z; Fiala-Beer E; Yang L; Phillips P; Goldstein D; Biankin A; Pirola R; Wilson JS; Apte MV, 2011, 'Hepatocyte growth factor: a potential therapeutic target in pancreatic cancer', in Journal of Gastroenterology and Hepatology, Wiley, pp. 20 - 20, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000295157300051&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2011
Fiala-Beer E; Xu Z; Phillips P; Yang L; Goldstein D; Pirola R; Wilson J; Apte M, 2010, 'Role of Pancreatic Stellate Cells in Pancreatic Cancer: The Urokinase Plasminogen Activator System', in PANCREAS, LIPPINCOTT WILLIAMS & WILKINS, pp. 1320 - 1320, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000282946600093&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2010
Vonlaufen A; Phillips PA; Xu Z; Zhang X; Yang L; Pirola RC; Wilson JS; Apte MV, 2010, 'Alcohol withdrawal promotes regression of pancreatic fibrosis via induction of pancreatic stellate cell (PSC) apoptosis', in Swiss Medical Weekly, EMH Schweizerischer Arzteverlag, pp. 12S - 12S, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000282844700040&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2010
Fiala-Beer E; Xu Z; Phillips PA; Yang L; Goldstein D; Pirola R; Wilson JS; Apte MV, 2010, 'Role of pancreatic stellate cells in pancreatic cancer: the urokinase plasminogen system', in Journal of Gastroenterology and Hepatology, Wiley, pp. A75 - A75, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000283321200202&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2010
Vonlaufen A; Phillips PA; Xu Z; Zhang X; Yang L; Pirola RC; Wilson JS; Apte MV, 2009, 'Alcohol withdrawal promotes regression of pancreatic fibrosis via induction of pancreatic stellate cell (PSC) apoptosis', in Journal of Gastroenterology and Hepatology, Wiley, pp. A333 - A333, presented at AGW, - , http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000270551200301&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2009
Vonlaufen A; Phillips P; Xu Z; Zhang X; Yang L; Pirola R; Wilson JS; Apte MV, 2009, 'Alcohol Withdrawal Promotes Regression of Pancreatic Fibrosis via Induction of Pancreatic Stellate Cell (PSC) Apoptosis', in GASTROENTEROLOGY, W B SAUNDERS CO-ELSEVIER INC, Chicago, IL, pp. A589 - A590, presented at Digestive Disease Week/110th Annual Meeting of the American-Gastroenterological-Association, Chicago, IL, 30 May 2009 - 04 June 2009, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000275277202889&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2009
Phillips PA; Yang L; Vonlaufen A; Xu Z; Biankin A; Goldstein D; Pirola R; Wilson JS; Apte MV, 2009, 'Heat shock proteins are induced during pancreatic stellate cell activation in pancreatic cancer', in Journal of Gastroenterology and Hepatology, Wiley, pp. A334 - A334, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000270551200304&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2009
Phillips PA; Chow E; Kaplan W; Cowley M; Vonlaufen A; Yang L; Goldstein D; Pirola R; Wilson J; Apte MV, 2009, 'Gene expression profiling of human pancreatic stellate cells and their roles in pancreatic cancer progression', in JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, WILEY-BLACKWELL PUBLISHING, INC, pp. A333 - A334, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000270551200303&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2009
Yang L; Phillips PA; Vonlaufen A; Kaplan W; Cowley M; Pirola R; Wilson J; Apte MV, 2009, 'Gene Expression Profiling of Rat Pancreatic Stellate Cells', in PANCREAS, LIPPINCOTT WILLIAMS & WILKINS, pp. 1064 - 1064, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000271225300412&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2009
Phillips P; Yang L; Vonlaufen A; Xu Z; Biankin AV; Goldstein D; Pirola R; Wilson JS; Apte MV, 2009, 'Heat Shock Proteins Are Induced During Pancreatic Stellate Cell Activation in Pancreatic Cancer', in GASTROENTEROLOGY, W B SAUNDERS CO-ELSEVIER INC, Chicago, IL, pp. A277 - A277, presented at Digestive Disease Week/110th Annual Meeting of the American-Gastroenterological-Association, Chicago, IL, 30 May 2009 - 04 June 2009, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000275277201376&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2009
Xu Z; Phillips PA; Vonlaufen A; Fiala-Beer E; Yang L; Biankin AV; Goldstein D; Pirola R; Wilson JS; Apte MV, 2009, 'Pancreatic stellate cells (stromal cells) migrate with pancreatic cancer cells to distant metastatic sites', in Journal of Gastroenterology and Hepatology, Wiley, pp. A334 - A335, presented at AGW, - , http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000270551200306&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2009
Apte MV; Vonlaufen A; Xu ZH; Phillips PA; Parker N; Pirola RC; Wilson JS, 2008, 'Pancreatic stellate cells: Major players in alcoholic pancreatitis and pancreatic cancer', in Alcoholism : Clinical and Experimental Research, Lippincott Williams & Wilkins, Philadelphia, PA, pp. 292A - 292A, presented at International-Society-for-Biomedical-Research-on-Alcoholism, Washington DC, USA, 27 June 2008 - 02 July 2008, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000256497201119&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
2008
Vonlaufen A; Xu Z; Phillips PA; Yang L; Zhang X; Pirola RC; Wilson JS; Apte MV, 2008, 'Abstinence promotes regression while continued alcohol intake promotes persistence of LPS-induced pancreatic injury in alcohol-fed rats', in Pancreas, LIPPINCOTT WILLIAMS & WILKINS, pp. 499 - 499, presented at American Pancreatic Association, - , http://dx.doi.org/10.1097/01.MPA.0000335405.92917.6c
2008
Vonlaufen A; Xu Z; Phillips PA; Yang L; Zhang X; Pirola RC; Wilson JS; Apte MV, 2008, 'Abstinence promotes regression while continued alcohol intake promotes persistence of LPS-induced pancreatic injury in alcohol-fed rats', in Journal of Gastroenterology and Hepatology, Wiley, pp. A308 - A308, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000259960100266&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2008
Vonlaufen A; Xu Z; Yang L; Phillips P; Zhang X; Pirola R; Wilson JS; Apte MV, 2008, 'Abstinence promotes regression while continued alcohol intake promotes persistence of LPS-Induced pancreatic injury in alcohol-fed rats', in GASTROENTEROLOGY, W B SAUNDERS CO-ELSEVIER INC, pp. A585 - A585, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000255101504277&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2008
Vonlaufen A; Xu ZH; Phillips PA; Zhang X; Yang L; Pirola RC; Wilson JS; Apte MV, 2008, 'Abstinence promotes regression while continued alcohol intake promotes persistence of LPS-induced pancreatic injury in alcohol-fed rats', in Alcoholism : Clinical and Experimental Research, Lippincott Williams & Wilkins, Philadelphia, PA, pp. 223A - 223A, presented at International-Society-for-Biomedical-Research-on-Alcoholism, Washington DC, USA, 27 June 2008 - 02 July 2008, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000256497200851&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
2008
Phillips PA; Yang L; Vonlaufen A; Xu Z; Pirola R; Wilson JS; Apte MV, 2008, 'Heat shock proteins are differentially regulated during pancreatic stellate cell activation', in Pancreas, LIPPINCOTT WILLIAMS & WILKINS, pp. 489 - 490, presented at American Pancreatic Association, - , http://dx.doi.org/10.1097/01.MPA.0000335361.86394.7f
2008
Phillips PA; Yang L; Vonlaufen A; Xu ZH; Pirola RC; Wilson JS; Apte MV, 2008, 'Heat shock proteins are differentially regulated during pancreatic stellate cell activation', in Journal of Gastroenterology and Hepatology, Blackwell Publishing Asia, Carlton, Victoria, Australia, pp. A308 - A308, presented at Journal of Gastroenterology and Hepatology, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000259960100265&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
2008
Xu ZH; Vonlaufen A; Yang L; Phillips PA; Fiala-Beer E; Biankin AV; Goldstein D; Pirola RC; Wilson JS; Apte MV, 2008, 'Pancreatic stellate cells stimulate angiogenesis in pancreatic cancer and accompany pancreatic cancer cells to distant metastatic sites', in Pancreas, Lippincott Williams & Wilkins, Philadelphia, PA, USA, pp. 502 - 503, presented at Pancreas, http://dx.doi.org/10.1097/01.MPA.0000335420.28357.d3
2008
Phillips P; Borja-Cacho D; Dudeja V; McCarroll J; Dawra R; Grizzle W; Vickers S; Saluja A, 2007, 'Triptolide a potential therapeutic candidate for pancreatic cancer', in JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS, ELSEVIER SCIENCE INC, New Orleans, LA, pp. S94 - S94, presented at 93rd Annual Clinical Congress of the American-College-of-Surgeons, New Orleans, LA, 07 October 2007 - 11 October 2007, http://dx.doi.org/10.1016/j.jamcollsurg.2007.06.235
2007
Phillips PA; Dudeja V; Borja-Cacho D; McCarroll J; Dawra R; Grizzle W; Vickers S; Saluja A, 2007, 'Triptolide inhibits tumor growth and local-regional spread in vivo via increased apoptosis and decreased heat shock protein 70 (HSP70)', in PANCREAS, LIPPINCOTT WILLIAMS & WILKINS, pp. 423 - 423, http://dx.doi.org/10.1097/01.mpa.0000297770.28197.06
2007
McCarroll J; Dudeja V; Phillips P; Dawra R; Borja-Cacho D; Vickers S; Wang C; Saluja A, 2007, 'Delivery of siRNA to pancreatic cancer cells using novel non-viral biodegradable nanoparticles', in PANCREAS, LIPPINCOTT WILLIAMS & WILKINS, pp. 416 - 416, http://dx.doi.org/10.1097/01.mpa.0000297747.27304.7d
2007
Dudeja V; Phillips P; Dawara R; Vickers SM; Saluja AK, 2007, 'Hsp70 inhibits apoptosis in pancreatic cancer cells by stabilization of lysosomes and attenuation of calcium signaling', in GASTROENTEROLOGY, W B SAUNDERS CO-ELSEVIER INC, Washington, DC, pp. A437 - A437, presented at Digestive Disease Week Meeting/108th Annual Meeting of the American-Gastroenterological-Association, Washington, DC, 19 May 2007 - 24 May 2007, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000245927603440&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2007
Zwolak P; Borja-Cacho D; Phillips PA; Dudeja V; Dawra R; Ankeny JS; Talukdar R; Chugh R; Vickers S; Saluja A, 2007, 'Myricetin induces apoptosis via caspase activation and inhibition of PI-3 kinase/Akt and c pathways in human pancreatic cells', in PANCREAS, LIPPINCOTT WILLIAMS & WILKINS, pp. 439 - 439, http://dx.doi.org/10.1097/01.mpa.0000297824.52312.fa
2007
Dudeja V; Phillips P; Dawra R; Vickers S; Saluja A, 2007, 'Hsp70 inhibits apoptosis in pancreatic cancer cells by two independent mechanisms: Attenuating cytosolic Ca2+ and stabilizing lysosomes', in PANCREAS, LIPPINCOTT WILLIAMS & WILKINS, pp. 399 - 399, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000252179100053&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2007
Phillips P; Dudeja V; Sharif R; Dawra R; Saluja A, 2006, 'The bioflavonoid myricetin induces pancreatic cancer cell death by a mechanism which is independent of HSP70', in GASTROENTEROLOGY, W B SAUNDERS CO-ELSEVIER INC, Los Angeles, CA, pp. A424 - A424, presented at Digestive Disease Week Meeting/107th Annual Meeting of the American-Gastroenterlogical-Association, Los Angeles, CA, 20 May 2006 - 25 May 2006, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000236961703162&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2006
Phillips PA; Dudeja V; Sharif R; Dawra R; Saluja A, 2006, 'Triptolide induces apoptosis in pancreatic cancer cells via inhibition of heat shock protein 70 (HSP70)', in PANCREAS, LIPPINCOTT WILLIAMS & WILKINS, pp. 491 - 491, http://dx.doi.org/10.1097/00006676-200611000-00184
2006
Dawra R; Sharif R; Singh VP; Phillips PA; Dudeja V; Saluja A, 2006, 'Exocrine pancreatic secretion is inhibited in L-arginine induced pancreatitis in mice', in PANCREAS, LIPPINCOTT WILLIAMS & WILKINS, pp. 455 - 455, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000241714500067&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2006
Joshi SB; Qu CF; Phillips PA; Pirola RC; Wilson JS; Goldstein D; Apte MV, 2005, 'Epithelial-stromal interactions in pancreatic cancer: do pancreatic cancer cells actively recruit host stromal cells for their own benefit?', in The Peter McCallum Institute (ed.), 6th Peter MacCallum Cancer Symposium, Molecular and Cell Biology of Cancer, 6th Peter MacCallum Cancer Symposium, Molecular and Cell Biology of Cancer, Melbourne, pp. 21 - 21, presented at 6th Peter MacCallum Cancer Symposium, Molecular and Cell Biology of Cancer, Melbourne, 14 November 2005 - 16 November 2005
2005
Mccarroll JA; Phillips PA; Santucci N; Pirola RC; Wilson JS; Apte MV, 2005, 'Does chronic ethanol administration sensitise rat pancreatic stellate cells to proinflammatory cytokynes?', in Gastroenterology, W B Saunders Co, Philadelphia, PA, USA, pp. A378 - A378, presented at Digestive Disease Week and the 106th Annual Meeting of the American Gastroenterological Association, Chicago Illinois USA, 14 May 2005 - 19 May 2005, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000228619303074&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
2005
Mccarroll JA; Qu CF; Phillips PA; Xu XH; Pirola RC; Wilson JS; Apte MV, 2004, 'Cholecystokinin activates intracellular signalling pathways in pancreatic stellate cells', in Pancreas, Lippincott Williams & Wilkins, Philadelphia, PA, USA, pp. 479 - 480, presented at 36th Annual Meeting of the American Pancreatic Association, Chicago Illinois USA, 03 November 2004 - 04 November 2004
2004
McCarroll J; Phillips P; Park S; Pirola R; Wilson JS; Apte MV, 2003, 'Oxidant stress induces the p38 mitogen activated protein kinase (p38 MAPK) signalling pathway in pancreatic stellate cells', in GASTROENTEROLOGY, W B SAUNDERS CO, ORLANDO, FLORIDA, pp. A616 - A616, presented at Digestive Disease Week 2003 Meeting/104th Annual Meeting of the American-Gastroenterological-Association, ORLANDO, FLORIDA, 17 May 2003 - 22 May 2003, http://dx.doi.org/10.1016/S0016-5085(03)83119-0
2003
Mews PJ; Phillips PA; Fahmy RG; McCaughan GW; Korsten MA; Pirola RC; Wilson JS; Apte MV, 2000, 'Pancreatic stellate cells are activated by tumour necrosis factor A (TNFA) - Implications for pancreatic fibrogenesis', in Gastroenterology, WB Saunders, pp. A424 - A424, http://dx.doi.org/10.1016/S0016-5085(00)83811-1
2000
Mews P; Phillips PA; Korsten MA; Pirola RC; Wilson JS; Apte MV, 2000, 'Collagen synthesis by pancreatic stellate cells - response to inflammatory cytokines', in Digestion, Karger, Basel, Switzerland, pp. 61:A258, presented at Digestion, 01 January 2000
2000
Mews P; Phillips PA; Korsten MA; Pirola RC; Wilson JS; Apte MV; Fahmy R; Mccaughan GW, 2000, 'Pancreatic stellate cells are activated by tumour necrosis factor a (TNFa) - implications for pancreatic fibrogenesis', in Podolsky DK (ed.), Digestive Disease Week and the 101st Annual Meeting of the American Gastroenterological Association, Digestive Disease Week and the 101st Annual Meeting of the American Gastroenterological Association, San Diego, California, USA, pp. 118:A424, presented at Digestive Disease Week and the 101st Annual Meeting of the American Gastroenterological Association, San Diego, California, USA, -
2000
Apte MV; Darby S; Phillips PA; Fahmy R; Mccaughan GW; Pirola RC; Wilson JS, 1999, 'Alcohol causes pancreatic fibrosis via activation of pancreatic stellate cells: an in vitro study', in Lam SK (ed.), Annual meeting of Gastroenterological Society of Australia, Annual meeting of Gastroenterological Society of Australia, pp. 14:A115, presented at Annual meeting of Gastroenterological Society of Australia, 01 October 1999
1999
Apte MV; Darby S; Phillips PA; Fahmy R; Mccaughan GW; Korsten MA; Pirola RC; Wilson JS, 1999, 'Role of pancreatic stellate cells in the pathogenesis of alcoholic pancreatic fibrosis', in Pancreas, Lippincott Williams & Wilkins, Philadelphia, PA, USA, pp. 0.87083333, presented at Annual meeting of American Pancreatic Association Chicago USA 11.99, 01 January 1999
1999