Nady Braidy

Senior Research Fellow

Research Interests

Dementia is one of the top five causes of death in Australia with an increasing incidence due to an aging population. Significant evidence points to oxidative stress (OS) as a major underlying factor in brain cell degeneration. Unfortunately, it is not known at what stage of life this OS begins in humans or what behaviours influence OS in the human brain. As OS underlies brain cell degeneration and the development of dementia, my current work will help to answer these questions and contribute to the development of strategies that will help maintain and improve brain and cellular function into older age.

ILP Research Interests (Will supervise ILP students)

Chemical And Drugs; Diseases And Disorders Life Sciences Psychiatric Disorders; 

Laboratory based teaching

PhD, Master and Honour students

Society Memberships & Professional Activities

American Alzheimer's Association; International College for Geriatric Psychoneuropharmacology (ICGP); Member of the Australian Society for Medical Research (ASMR); Member of the Australian Neuroscience Society (ANS); International Society for Tryptophan Research (ISTRY); Neurotoxicity Society

Funding Sources

National Health and Medical Research Council; Australian Research Council; Alzheimer's Australia Viertel Foundation; UNSW Faculty of Medicine

Other Postgraduate Research Honours projects

- Plasma biomarkers of ageing

- Plasma lipidome changes associated with ageing and neurodegenerative disease of ageing. In particular, plasma phospholipids and fatty acid associations with ageing, health status (frailty, MCI, APOE allele, etc) and disorders such as MCI and dementia.

- Peripheral blood markers of vascular risk and/or CVD which alone, or in combination with markers of AD, can predict the onset of clinical symptoms and vascular dementia progression

- Promotion of cellular nicotinamide adenine dinucleotide (NAD+) anabolism as a strategy to improve cellular senescence and cognitive function.

- Develop and test a series of novel superparamagnetic iron oxide nanoparticles that can penetrate the blood-brain barrier (BBB) and provide a superparamagnetic signal for amyloid imaging using MRI with limited toxicity.

- In vitro and in vivo studies on polyphenols as an integral strategy in preventing and treating diseases associated with neurodegeneration.

publications

Journal articles
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Ulanova M; Poljak A; Wen W; Bongers A; Gloag L; Gooding J; Tilley R; Sachdev P; Braidy N, 2020, 'Nanoparticles as contrast agents for the diagnosis of Alzheimer’s disease: a systematic review', Nanomedicine, http://dx.doi.org/10.2217/nnm-2019-0316
2020
Chiang S; Kalinowski DS; Dharmasivam M; Braidy N; Richardson DR; Huang MLH, 2020, 'The potential of the novel NAD+ supplementing agent, SNH6, as a therapeutic strategy for the treatment of Friedreich's ataxia', Pharmacological Research, http://dx.doi.org/10.1016/j.phrs.2020.104680
2020
Hosseini M; Poljak A; Braidy N; Crawford J; Sachdev P, 2020, 'Blood fatty acids in Alzheimer's disease and mild cognitive impairment: A meta-analysis and systematic review.', Ageing Res Rev, pp. 101043, http://dx.doi.org/10.1016/j.arr.2020.101043
2020
Wu Z; Palanimuthu D; Braidy N; Salikin NH; Egan S; Huang MLH; Richardson DR, 2020, 'Novel multifunctional iron chelators of the aroyl nicotinoyl hydrazone class that markedly enhance cellular NAD+/NADH ratios', British Journal of Pharmacology, http://dx.doi.org/10.1111/bph.14963
2020
Braidy N; Liu Y, 2020, 'NAD+ therapy in age-related degenerative disorders: A benefit/risk analysis', Experimental Gerontology, vol. 132, http://dx.doi.org/10.1016/j.exger.2020.110831
2020
Sevindik M; Akgul H; Selamoglu Z; Braidy N, 2020, 'Antioxidant and Antigenotoxic Potential of Infundibulicybe geotropa Mushroom Collected from Northwestern Turkey', Oxidative Medicine and Cellular Longevity, vol. 2020, pp. 5620484, http://dx.doi.org/10.1155/2020/5620484
2020
Gloag L; Mehdipour M; Ulanova M; Mariandry K; Nichol MA; Hernández-Castillo DJ; Gaudet J; Qiao R; Zhang J; Nelson M; Thierry B; Alvarez-Lemus MA; Tan TT; Gooding JJ; Braidy N; Sachdev PS; Tilley RD, 2020, 'Zero valent iron core–iron oxide shell nanoparticles as small magnetic particle imaging tracers', Chemical Communications, http://dx.doi.org/10.1039/c9cc08972a
2020
Farzaei MH; Bahramsoltani R; Abbasabadi Z; Braidy N; Nabavi SM, 2019, 'Role of green tea catechins in prevention of age-related cognitive decline: Pharmacological targets and clinical perspective', Journal of Cellular Physiology, vol. 234, pp. 2447 - 2459, http://dx.doi.org/10.1002/jcp.27289
2019
Wong MWK; Braidy N; Crawford J; Pickford R; Song F; Mather KA; Attia J; Brodaty H; Sachdev P; Poljak A, 2019, 'APOE Genotype Differentially Modulates Plasma Lipids in Healthy Older Individuals, with Relevance to Brain Health', Journal of Alzheimer's Disease, vol. 72, pp. 703 - 716, http://dx.doi.org/10.3233/JAD-190524
2019
Dehhaghi M; Tan V; Heng B; Braidy N; Mohammadipanah F; Guillemin GJ, 2019, 'Neuroprotective Effect of Myxobacterial Extracts on Quinolinic Acid-Induced Toxicity in Primary Human Neurons', Neurotoxicity Research, vol. 35, pp. 281 - 290, http://dx.doi.org/10.1007/s12640-018-9945-8
2019
Wong MWK; Braidy N; Pickford R; Sachdev PS; Poljak A, 2019, 'Comparison of Single Phase and Biphasic Extraction Protocols for Lipidomic Studies Using Human Plasma', Frontiers in Neurology, vol. 10, pp. 1 - 11, http://dx.doi.org/10.3389/fneur.2019.00879
2019
Vacca RA; Bawari S; Valenti D; Tewari D; Nabavi SF; Shirooie S; Sah AN; Volpicella M; Braidy N; Nabavi SM, 2019, 'Down syndrome: Neurobiological alterations and therapeutic targets', Neuroscience and Biobehavioral Reviews, vol. 98, pp. 234 - 255, http://dx.doi.org/10.1016/j.neubiorev.2019.01.001
2019
Braidy N; Berg J; Clement J; Khorshidi F; Poljak A; Jayasena T; Grant R; Sachdev PS, 2019, 'Role of Nicotinamide Adenine Dinucleotide and Related Precursors as Therapeutic Targets for Age-Related Degenerative Diseases: Rationale, Biochemistry, Pharmacokinetics, and Outcomes', Antioxidants and Redox Signaling, vol. 30, pp. 251 - 294, http://dx.doi.org/10.1089/ars.2017.7269
2019
Wong MWK; Braidy N; Pickford R; Vafaee F; Crawford J; Muenchhoff J; Schofield P; Attia J; Brodaty H; Sachdev P; Poljak A, 2019, 'Plasma lipidome variation during the second half of the human lifespan is associated with age and sex but minimally with BMI', PLoS ONE, vol. 14, pp. e0214141, http://dx.doi.org/10.1371/journal.pone.0214141
2019
Öztürk Y; Günaydın C; Yalçın F; Nazıroğlu M; Braidy N, 2019, 'Resveratrol enhances apoptotic and oxidant effects of paclitaxel through TRPM2 channel activation in DBTRG glioblastoma cells', Oxidative Medicine and Cellular Longevity, vol. 2019, pp. 4619865, http://dx.doi.org/10.1155/2019/4619865
2019
Nabavi SF; Sureda A; Sanches-Silva A; Pandima Devi K; Ahmed T; Shahid M; Sobarzo-Sánchez E; Dacrema M; Daglia M; Braidy N; Vacca RA; Berindan-Neagoe I; Gulei D; Barreca D; Banach M; Nabavi SM; Dehpour AR; Shirooie S, 2019, 'Novel therapeutic strategies for stroke: The role of autophagy', Critical Reviews in Clinical Laboratory Sciences, vol. 56, pp. 182 - 199, http://dx.doi.org/10.1080/10408363.2019.1575333
2019
Clement J; Wong M; Poljak A; Sachdev P; Braidy N, 2019, 'The Plasma NAD⁺ Metabolome Is Dysregulated in "normal" Aging', Rejuvenation Research, vol. 22, pp. 121 - 130, http://dx.doi.org/10.1089/rej.2018.2077
2019
Ertilav K; Nazıroğlu M; Ataizi ZS; Braidy N, 2019, 'Selenium Enhances the Apoptotic Efficacy of Docetaxel Through Activation of TRPM2 Channel in DBTRG Glioblastoma Cells', Neurotoxicity Research, vol. 35, pp. 797 - 808, http://dx.doi.org/10.1007/s12640-019-0009-5
2019
Chen Z; Jiang R; Chen M; Zheng J; Chen M; Braidy N; Liu S; Liu G; Maimaitiming Z; Shen T; Dunaief JL; Vulpe CD; Anderson GJ; Chen H, 2019, 'Multi-copper ferroxidase deficiency leads to iron accumulation and oxidative damage in astrocytes and oligodendrocytes', Scientific Reports, vol. 9, http://dx.doi.org/10.1038/s41598-019-46019-9
2019
Braidy N; Zarka M; Jugder B-E; Welch J; Jayasena T; Chan DKY; Sachdev P; Bridge W, 2019, 'The Precursor to Glutathione (GSH), γ-Glutamylcysteine (GGC), Can Ameliorate Oxidative Damage and Neuroinflammation Induced by Aβ40 Oligomers in Human Astrocytes', Frontiers in Aging Neuroscience, vol. 11, pp. 1 - 1, http://dx.doi.org/10.3389/fnagi.2019.00177
2019
Nabavi SM; Nabavi SF; Sureda A; Caprioli G; Iannarelli R; Sokeng AJT; Braidy N; Khanjani S; Moghaddam AH; Atanasov AG; Daglia M; Maggi F, 2018, 'The water extract of tutsan (Hypericum androsaemum L.) red berries exerts antidepressive-like effects and in vivo antioxidant activity in a mouse model of post-stroke depression', Biomedicine and Pharmacotherapy, vol. 99, pp. 290 - 298, http://dx.doi.org/10.1016/j.biopha.2018.01.073
2018
Liu Y; Clement J; Grant R; Sachdev PS; Braidy N, 2018, 'Quantitation of NAD+: Why do we need to measure it?', BBA - Biochimica et Biophysica Acta, vol. 1862, pp. 2527 - 2532, http://dx.doi.org/10.1016/j.bbagen.2018.07.023
2018
Palanimuthu D; Wu Z; Jansson PJ; Braidy N; Bernhardt PV; Richardson DR; Kalinowski DS, 2018, 'Novel chelators based on adamantane-derived semicarbazones and hydrazones that target multiple hallmarks of Alzheimer's disease', Dalton Transactions, vol. 47, pp. 7190 - 7205, http://dx.doi.org/10.1039/c8dt01099d
2018
Braidy N; Grant R; Sachdev PS, 2018, 'Nicotinamide adenine dinucleotide and its related precursors for the treatment of Alzheimer's disease', Current Opinion in Psychiatry, vol. 31, pp. 160 - 166, http://dx.doi.org/10.1097/yco.0000000000000394
2018
Amiri M; Braidy N; Aminzadeh M, 2018, 'Protective Effects of Fibroblast Growth Factor 21 Against Amyloid-Beta1–42-Induced Toxicity in SH-SY5Y Cells', Neurotoxicity Research, vol. 34, pp. 574 - 583, http://dx.doi.org/10.1007/s12640-018-9914-2
2018
Bustamante S; Jayasena T; Richani D; Gilchrist RB; Wu LE; Sinclair DA; Sachdev PS; Braidy N, 2018, 'Quantifying the cellular NAD+ metabolome using a tandem liquid chromatography mass spectrometry approach', Metabolomics, vol. 14, http://dx.doi.org/10.1007/s11306-017-1310-z
2018
Seyedsadjadi N; Berg J; Bilgin AA; Braidy N; Salonikas C; Grant R, 2018, 'High protein intake is associated with low plasma NAD+ levels in a healthy human cohort', PLoS ONE, vol. 13, http://dx.doi.org/10.1371/journal.pone.0201968
2018
Braidy N; Izadi M; Sureda A; Jonaidi-Jafari N; Banki A; Nabavi SF; Seyed MN, 2018, 'Therapeutic relevance of ozone therapy in degenerative diseases: Focus on diabetes and spinal pain', Journal of Cellular Physiology, vol. 233, pp. 2705 - 2714, http://dx.doi.org/10.1002/jcp.26044
2018
Mello FD; Braidy N; Marçal H; Guillemin G; Nabavi SM; Neilan BA, 2018, 'Mechanisms and Effects Posed by Neurotoxic Products of Cyanobacteria/Microbial Eukaryotes/Dinoflagellates in Algae Blooms: a Review', Neurotoxicity Research, vol. 33, pp. 153 - 167, http://dx.doi.org/10.1007/s12640-017-9780-3
2018
Valenti D; Braidy N; De Rasmo D; Signorile A; Rossi L; Atanasov AG; Volpicella M; Henrion-Caude A; Nabavi SM; Vacca RA, 2018, 'Mitochondria as pharmacological targets in Down syndrome', Free Radical Biology and Medicine, vol. 114, pp. 69 - 83, http://dx.doi.org/10.1016/j.freeradbiomed.2017.08.014
2018
Nabavi SF; Sureda A; Dehpour AR; Shirooie S; Silva AS; Devi KP; Ahmed T; Ishaq N; Hashim R; Sobarzo-Sánchez E; Daglia M; Braidy N; Volpicella M; Vacca RA; Nabavi SM, 2018, 'Regulation of autophagy by polyphenols: Paving the road for treatment of neurodegeneration', Biotechnology Advances, vol. 36, pp. 1768 - 1778, http://dx.doi.org/10.1016/j.biotechadv.2017.12.001
2018
Liu Y; Braidy N; Poljak A; Chan DK; Sachdev PS, 2018, 'Cerebral small vessel disease and the risk of Alzheimer's disease: A systematic review', Ageing Research Reviews, vol. 47, pp. 41 - 48, http://dx.doi.org/10.1016/j.arr.2018.06.002
2018
Ahmed T; Javed S; Javed S; Tariq A; Šamec D; Tejada S; Nabavi SF; Braidy N; Nabavi SM, 2017, 'Resveratrol and Alzheimer’s Disease: Mechanistic Insights', Molecular Neurobiology, vol. 54, pp. 2622 - 2635, http://dx.doi.org/10.1007/s12035-016-9839-9
2017
Srinivasan V; Braidy N; Xu YH; Xie P; Kancherla K; Chandramohan S; Chan EKW; Chan DKY, 2017, 'Association of genetic polymorphisms of claudin-1 with small vessel vascular dementia', Clinical and Experimental Pharmacology and Physiology, vol. 44, pp. 623 - 630, http://dx.doi.org/10.1111/1440-1681.12747
2017
D‘Mello F; Braidy N; Marçal H; Guillemin G; Rossi F; Chinian M; Laurent D; Teo C; Neilan BA, 2017, 'Cytotoxic Effects of Environmental Toxins on Human Glial Cells', Neurotoxicity Research, vol. 31, pp. 245 - 258, http://dx.doi.org/10.1007/s12640-016-9678-5
2017
Lee JM; Tan V; Lovejoy D; Braidy N; Rowe DB; Brew BJ; Guillemin GJ, 2017, 'Involvement of quinolinic acid in the neuropathogenesis of amyotrophic lateral sclerosis', Neuropharmacology, vol. 112, pp. 346 - 364, http://dx.doi.org/10.1016/j.neuropharm.2016.05.011
2017
Naziroğlu M; Braidy N, 2017, 'Thermo-sensitive TRP channels: Novel targets for treating chemotherapy-induced peripheral pain', Frontiers in Physiology, vol. 8, http://dx.doi.org/10.3389/fphys.2017.01040
2017
Braidy N; Poljak A; Marjo C; Rutlidge H; Rich A; Jugder B-E; Jayasena T; Inestrosa N; Sachdev P, 2017, 'Identification of cerebral metal ion imbalance in the brain of ageing Octodon degus', Frontiers in Aging Neuroscience, vol. 9, pp. 66 - 66, http://dx.doi.org/10.3389/fnagi.2017.00066
2017
Tejada S; Setzer WN; Daglia M; Nabavi SF; Sureda A; Braidy N; Gortzi O; Nabavi SM, 2017, 'Neuroprotective Effects of Ellagitannins: A Brief Review', Current drug targets, vol. 18, pp. 1518 - 1528, http://dx.doi.org/10.2174/1389450117666161005112002
2017
Devi KP; Malar DS; Braidy N; Nabavi SM; Nabavi SF, 2017, 'A Mini Review on the Chemistry and Neuroprotective Effects of Silymarin', Current drug targets, vol. 18, pp. 1529 - 1536, http://dx.doi.org/10.2174/1389450117666161227125121
2017
Talarek S; Listos J; Barreca D; Tellone E; Sureda A; Nabavi SF; Braidy N; Nabavi SM, 2017, 'Neuroprotective effects of honokiol: from chemistry to medicine', BioFactors, vol. 43, pp. 760 - 769, http://dx.doi.org/10.1002/biof.1385
2017
Lim CK; Fernández-Gomez FJ; Braidy N; Estrada C; Costa C; Costa S; Bessede A; Fernandez-Villalba E; Zinger A; Herrero MT; Guillemin GJ, 2017, 'Involvement of the kynurenine pathway in the pathogenesis of Parkinson's disease', Progress in Neurobiology, vol. 155, pp. 76 - 95, http://dx.doi.org/10.1016/j.pneurobio.2015.12.009
2017
Gokoolparsadh A; Fang Z; Braidy N; Lin P; Pardy CJ; Eapen V; Clarke R; Voineagu I, 2017, 'Transcriptional response to mitochondrial protease IMMP2L knockdown in human primary astrocytes', Biochemical and Biophysical Research Communications, vol. 482, pp. 1252 - 1258, http://dx.doi.org/10.1016/j.bbrc.2016.12.024
2017
Shariflou S; Georgevsky D; Mansour H; Rezaeian M; Hosseini N; Gani F; Gupta V; Braidy N; Golzan SM, 2017, 'Diagnostic and prognostic potential of retinal biomarkers in early on-set Alzheimer’s disease', Current Alzheimer Research, vol. 14, pp. 1000 - 1007, http://dx.doi.org/10.2174/1567205014666170329114445
2017
Daglia M; Lorenzo AD; Nabavi SF; Sureda A; Khanjani S; Moghaddam AH; Braidy N; Nabavi SM, 2017, 'Improvement of antioxidant defences and mood status by oral GABA tea administration in a mouse model of post-stroke depression', Nutrients, vol. 9, http://dx.doi.org/10.3390/nu9050446
2017
Braidy N, 2017, 'Meet our editorial board member', Current Alzheimer Research, vol. 14, pp. 123, http://dx.doi.org/10.2174/156720501402170109162607
2017
Mirzaei M; Gupta VB; Chick JM; Greco TM; Wu Y; Chitranshi N; Wall RV; Hone E; Deng L; Dheer Y; Abbasi M; Rezaeian M; Braidy N; You Y; Salekdeh GH; Haynes PA; Molloy MP; Martins R; Cristea IM; Gygi SP; Graham SL; Gupta VK, 2017, 'Age-related neurodegenerative disease associated pathways identified in retinal and vitreous proteome from human glaucoma eyes', Scientific Reports, vol. 7, http://dx.doi.org/10.1038/s41598-017-12858-7
2017
Braidy N; Behzad S; Habtemariam S; Ahmed T; Daglia M; Nabavi SM; Sobarzo-Sanchez E; Nabavi SF, 2017, 'Neuroprotective effects of citrus fruit-derived flavonoids, nobiletin and tangeretin in Alzheimer’s and Parkinson’s disease', CNS and Neurological Disorders - Drug Targets, vol. 16, pp. 387 - 397, http://dx.doi.org/10.2174/1871527316666170328113309
2017
Wong MW; Braidy N; Poljak A; Sachdev PS, 2017, 'The application of lipidomics to biomarker research and pathomechanisms in Alzheimer's disease', Current Opinion in Psychiatry, vol. 30, pp. 136 - 144, http://dx.doi.org/10.1097/YCO.0000000000000303
2017
Wong MW; Braidy N; Poljak A; Pickford R; Thambisetty M; Sachdev PS, 2017, 'Dysregulation of lipids in Alzheimer's disease and their role as potential biomarkers', Alzheimers Dement, vol. 13, pp. 810 - 827, http://dx.doi.org/10.1016/j.jalz.2017.01.008
2017
Ajami M; Pazoki-Toroudi H; Amani H; Nabavi SF; Braidy N; Vacca RA; Atanasov AG; Mocan A; Nabavi SM, 2017, 'Therapeutic role of sirtuins in neurodegenerative disease and their modulation by polyphenols', Neuroscience and Biobehavioral Reviews, vol. 73, pp. 39 - 47, http://dx.doi.org/10.1016/j.neubiorev.2016.11.022
2017
Braidy N; Grant R, 2017, 'Kynurenine pathway metabolism and neuroinflammatory disease', Neural Regeneration Research, vol. 12, pp. 39 - 42, http://dx.doi.org/10.4103/1673-5374.198971
2017
Rahimifard M; Maqbool F; Moeini-Nodeh S; Niaz K; Abdollahi M; Braidy N; Nabavi SM; Nabavi SF, 2017, 'Targeting the TLR4 signaling pathway by polyphenols: A novel therapeutic strategy for neuroinflammation', Ageing Research Reviews, vol. 36, pp. 11 - 19, http://dx.doi.org/10.1016/j.arr.2017.02.004
2017
Gokoolparsadh A; Fang Z; Braidy N; Voineagu I, 2017, 'Topoisomerase I inhibition leads to length-dependent gene expression changes in human primary astrocytes', Genomics Data, vol. 11, pp. 113 - 115, http://dx.doi.org/10.1016/j.gdata.2016.12.005
2017
Braidy N; Jugder B-E; Poljak A; Jayasena T; Nabavi SM; Sachdev P; Grant R, 2017, 'Molecular targets of Tannic Acid in Alzheimer’s disease', Curr Alzheimer Res, vol. 14, pp. 861 - 869, http://dx.doi.org/10.2174/1567205014666170206163158
2017
Chan DKY; Xu YH; Chan LKM; Braidy N; Mellick GD, 2017, 'Mini-review on initiatives to interfere with the propagation and clearance of alpha-synuclein in Parkinson's disease', Translational Neurodegeneration, vol. 6, http://dx.doi.org/10.1186/s40035-017-0104-6
2017
Braidy N; Poljak A; Marjo C; Rutlidge H; Rich A; Jugder BE; Jayasena T; Inestrosa NC; Sachdev PS, 2017, 'Corrigendum: Identification of cerebral metal ion imbalance in the brain of ageing octodon degus [Front. Aging Neurosci., 9, (2017) (66)] DOI: 10.3389/fnagi.2017.00066', Frontiers in Aging Neuroscience, vol. 9, http://dx.doi.org/10.3389/fnagi.2017.00134
2017
Subash S; Essa MM; Braidy N; Al-Jabri A; Vaishnav R; Al-Adawi S; Al-Asmi A; Guillemin GJ, 2016, 'Consumption of fig fruits grown in Oman can improve memory, anxiety, and learning skills in a transgenic mice model of Alzheimer's disease', Nutritional Neuroscience, vol. 19, pp. 475 - 483, http://dx.doi.org/10.1179/1476830514Y.0000000131
2016
Nabavi SF; Tejada S; Setzer WN; Gortzi O; Sureda A; Braidy N; Daglia M; Manayi A; Nabavi SM, 2016, 'Chlorogenic acid and mental diseases: From chemistry to medicine', Current Neuropharmacology, vol. 14, http://dx.doi.org/10.2174/1570159X14666160325120625
2016
Nabavi SF; Braidy N; Habtemariam S; Sureda A; Manayi A; Nabavi SM, 2016, 'Neuroprotective effects of fisetin in alzheimer’s and parkinson’s diseases: From chemistry to medicine', Current Topics in Medicinal Chemistry, vol. 16, pp. 1910 - 1915
2016
Nabavi SF; Braidy N; Orhan IE; Badiee A; Daglia M; Nabavi SM, 2016, 'Rhodiola rosea L. and Alzheimer's Disease: From Farm to Pharmacy', Phytotherapy Research, vol. 30, pp. 532 - 539, http://dx.doi.org/10.1002/ptr.5569
2016
Braidy N; Rossez H; Lim CK; Jugder BE; Brew BJ; Guillemin GJ, 2016, 'Characterization of the Kynurenine Pathway in CD8+ Human Primary Monocyte-Derived Dendritic Cells', Neurotoxicity Research, vol. 30, pp. 620 - 632, http://dx.doi.org/10.1007/s12640-016-9657-x
2016
Pazoki-Toroudi H; Amani H; Ajami M; Nabavi SF; Braidy N; Kasi PD; Nabavi SM, 2016, 'Targeting mTOR signaling by polyphenols: A new therapeutic target for ageing', Ageing Research Reviews, vol. 31, pp. 55 - 66, http://dx.doi.org/10.1016/j.arr.2016.07.004
2016
Jugder BE; Ertan H; Wong YK; Braidy N; Manefield M; Marquis CP; Lee M, 2016, 'Genomic, transcriptomic and proteomic analyses of dehalobacter UNSWDHB in response to chloroform', Environmental Microbiology Reports, vol. 8, pp. 814 - 824, http://dx.doi.org/10.1111/1758-2229.12444
2016
Braidy N; Essa MM; Poljak A; Selvaraju S; Al-Adawi S; Manivasagm T; Thenmozhi AJ; Ooi L; Sachdev P; Guillemin GJ, 2016, 'Consumption of pomegranates improves synaptic function in a transgenic mice model of Alzheimer's disease', Oncotarget, vol. 7, pp. 64589 - 64604, http://dx.doi.org/10.18632/oncotarget.10905
2016
Ahmed T; Setzer WN; Nabavi SF; Orhan IE; Braidy N; Sobarzo-Sanchez E; Nabavi SM, 2016, 'Insights into effects of ellagic acid on the nervous system: A mini review', Current Pharmaceutical Design, vol. 22, pp. 1350 - 1360, http://dx.doi.org/10.2174/1381612822666160125114503
2016
Suganthy N; Devi KP; Nabavi SF; Braidy N; Nabavi SM, 2016, 'Bioactive effects of quercetin in the central nervous system: Focusing on the mechanisms of actions', Biomedicine and Pharmacotherapy, vol. 84, pp. 892 - 908, http://dx.doi.org/10.1016/j.biopha.2016.10.011
2016
Cao P; Braidy N; Zarka M; Welch J; Bridge W, 2016, 'Therapeutic Approaches to Modulating Glutathione Levels as a Pharmacological Strategy in Alzheimer's Disease (vol 12, pg 298, 2015)', CURRENT ALZHEIMER RESEARCH, vol. 13, pp. 1198 - 1198, http://dx.doi.org/10.2174/156720501310160825221218
2016
de Oliveira MR; Nabavi SM; Braidy N; Setzer WN; Ahmed T; Nabavi SF, 2016, 'Quercetin and the mitochondria: A mechanistic view', Biotechnology Advances, vol. 34, pp. 532 - 549, http://dx.doi.org/10.1016/j.biotechadv.2015.12.014
2016
Jayasena T; Poljak A; Braidy N; Zhong L; Rowlands B; Muenchhoff J; Grant R; Smythe G; Teo C; Raftery M; Sachdev PS, 2016, 'Application of targeted mass spectrometry for the quantification of sirtuins in the central nervous system', Scientific Reports, vol. 6, pp. 35391 - 35391, http://dx.doi.org/10.1038/srep35391
2016
Vacca RA; Valenti D; Caccamese S; Daglia M; Braidy N; Nabavi SM, 2016, 'Plant polyphenols as natural drugs for the management of Down syndrome and related disorders', Neuroscience and Biobehavioral Reviews, vol. 71, pp. 865 - 877, http://dx.doi.org/10.1016/j.neubiorev.2016.10.023
2016
Ahmed T; Raza SH; Maryam A; Setzer WN; Braidy N; Nabavi SF; De Oliveira MR; Nabavi SM, 2016, 'Ginsenoside Rb1 as a neuroprotective agent: A review', Brain Research Bulletin, vol. 125, pp. 30 - 43, http://dx.doi.org/10.1016/j.brainresbull.2016.04.002
2016
Braidy N; Jugder BE; Poljak A; Jayasena T; Mansour H; Nabavi SM; Sachdev P; Grant R, 2016, 'Resveratrol as a potential therapeutic candidate for the treatment and management of alzheimer’s disease', Current Topics in Medicinal Chemistry, vol. 16, pp. 1951 - 1960, http://dx.doi.org/10.2174/1568026616666160204121431
2016
Srinivasan V; Braidy N; Chan EKW; Xu YH; Chan DKY, 2016, 'Genetic and environmental factors in vascular dementia: An update of blood brain barrier dysfunction', Clinical and Experimental Pharmacology and Physiology, vol. 43, pp. 515 - 521, http://dx.doi.org/10.1111/1440-1681.12558
2016
Jugder ; Welch J; Braidy N; Marquis CP, 2016, 'Construction and use of a Cupriavidus necator H16 soluble hydrogenase promoter', PeerJ, vol. 4, pp. e2269 - e2269, http://dx.doi.org/10.7717/peerj.2269
2016
Chan DKY; Braidy N; Xu YH; Chataway T; Guo F; Guillemin GJ; Teo C; Gai WP, 2016, 'Interference of α-Synuclein Uptake by Monomeric β-Amyloid1–40 and Potential Core Acting Site of the Interference', Neurotoxicity Research, vol. 30, pp. 479 - 485, http://dx.doi.org/10.1007/s12640-016-9644-2
2016
Grant R; Berg J; Braidy N, 2016, 'Promoting NAD+ metabolism: A new target for treating degenerative disease', Journal of the Australasian College of Nutritional and Environmental Medicine, vol. 35, pp. 3 - 10
2016
Inestrosa NC; Ríos JA; Cisternas P; Tapia-Rojas C; Rivera DS; Braidy N; Zolezzi JM; Godoy JA; Carvajal FJ; Ardiles AO; Bozinovic F; Palacios AG; Sachdev PS, 2015, 'Age Progression of Neuropathological Markers in the Brain of the Chilean Rodent Octodon degus, a Natural Model of Alzheimer's Disease', Brain Pathology, vol. 25, pp. 679 - 691, http://dx.doi.org/10.1111/bpa.12226
2015
Bastías-Candia S; Braidy N; Zolezzi JM; Inestrosa NC, 2015, 'Teneurins and Alzheimer's disease: A suggestive role for a unique family of proteins', Medical Hypotheses, vol. 84, pp. 402 - 407, http://dx.doi.org/10.1016/j.mehy.2015.01.026
2015
Nabavi SF; Braidy N; Gortzi O; Sobarzo-Sanchez E; Daglia M; Skalicka-Woźniak K; Nabavi SM, 2015, 'Luteolin as an anti-inflammatory and neuroprotective agent: A brief review', Brain Research Bulletin, vol. 119, pp. 1 - 11, http://dx.doi.org/10.1016/j.brainresbull.2015.09.002
2015
Subash S; Braidy N; Essa MM; Zayana AB; Ragini V; Al-Adawi S; Al-Asmi A; Guillemin GJ, 2015, 'Long-term (15mo) dietary supplementation with pomegranates from Oman attenuates cognitive and behavioral deficits in a transgenic mice model of Alzheimer's disease', Nutrition, vol. 31, pp. 223 - 229, http://dx.doi.org/10.1016/j.nut.2014.06.004
2015
Nabavi SF; Braidy N; Habtemariam S; Orhan IE; Daglia M; Manayi A; Gortzi O; Nabavi SM, 2015, 'Neuroprotective effects of chrysin: From chemistry to medicine', Neurochemistry International, vol. 90, pp. 224 - 231, http://dx.doi.org/10.1016/j.neuint.2015.09.006
2015
Braidy N; nabavi SM; Daglia MD; Nabavi SF, 2015, 'Natural products, micronutrients, and nutraceuticals for the treatment of depression', Nutritional Neuroscience, vol. 20, pp. 180 - 194, http://dx.doi.org/10.1080/1028415X.2015.1103461
2015
Braidy N; Poljak A; Jayasena T; Mansour H; Inestrosa NC; Sachdev PS, 2015, 'Accelerating Alzheimer's research through 'natural' animal models', Current Opinion in Psychiatry, vol. 28, pp. 155 - 164, http://dx.doi.org/10.1097/YCO.0000000000000137
2015
Jayasena T; Poljak A; Braidy N; Smythe G; Raftery M; Hill M; Brodaty H; Trollor J; Kochan N; Sachdev P, 2015, 'Upregulation of glycolytic enzymes, mitochondrial dysfunction and increased cytotoxicity in glial cells treated with Alzheimer's disease plasma', PLoS ONE, vol. 10, pp. e0116092, http://dx.doi.org/10.1371/journal.pone.0116092
2015
Braidy N; Poljak A; Grant R; Jayasena T; Mansour H; Chan-Ling T; Smythe G; Sachdev P; Guillemin GJ, 2015, 'Differential expression of sirtuins in the aging rat brain', Frontiers in Cellular Neuroscience, vol. 9, http://dx.doi.org/10.3389/fncel.2015.00167
2015
Sheipouri D; Grant R; Bustamante S; Lovejoy D; Guillemin GJ; Braidy N, 2015, 'Characterisation of the kynurenine pathway in skin-derived fibroblasts and keratinocytes', Journal of Cellular Biochemistry, vol. 116, pp. 903 - 922, http://dx.doi.org/10.1002/jcb.25019
2015
Braidy N; Zarka M; Welch J; Bridge W, 2015, 'Therapeutic approaches to modulating glutathione levels as a pharmacological strategy in Alzheimer’s disease', Current Alzheimer Research, vol. 12, pp. 298 - 313, http://dx.doi.org/10.2174/1567205012666150302160308
2015
Al-Adawi S; Braidy N; Essa M; Al-Azri F; Hussain S; Al-Sibani N; Al-Khabouri J; Al-Asmi A; Al-Mashani A, 2015, 'Cognitive profiles in patients with multi-infarct dementia: an Omani study (vol 4, pg 271, 2014)', DEMENTIA AND GERIATRIC COGNITIVE DISORDERS EXTRA, vol. 5, pp. 285 - 285, http://dx.doi.org/10.1159/000430968
2015
Nabavi SM; Habtemariam S; Daglia M; Braidy N; Loizzo MR; Tundis R; Nabavi SF, 2015, 'Neuroprotective effects of ginkgolide B against ischemic stroke: A review of current literature', Current Topics in Medicinal Chemistry, vol. 15, pp. 2222 - 2232, http://dx.doi.org/10.2174/1568026615666150610142647
2015
Chiu AS; Braidy N; Marçal H; Welch JH; Gehringer MM; Guillemin GJ; Neilan BA, 2015, 'Global cellular responses to β-methyl-amino-l-alanine (BMAA) by olfactory ensheathing glial cells (OEC)', Toxicon, vol. 99, pp. 136 - 145, http://dx.doi.org/10.1016/j.toxicon.2015.03.009
2015
Subash S; Essa MM; Braidy N; Awlad-Thani K; Vaishnav R; Al-Adawi S; Al-Asmi A; Guillemin GJ, 2015, 'Diet rich in date palm fruits improves memory, learning and reduces beta amyloid in transgenic mouse model of Alzheimer's disease', Journal of Ayurveda and Integrative Medicine, vol. 6, pp. 111 - 120, http://dx.doi.org/10.4103/0975-9476.159073
2015
Braidy N; Matin A; Rossi F; Chinain M; Laurent D; Guillemin GJ, 2014, 'Neuroprotective effects of rosmarinic acid on ciguatoxin in primary human neurons', Neurotoxicity Research, vol. 25, pp. 226 - 234, http://dx.doi.org/10.1007/s12640-013-9429-9
2014
Chen C; Upton C; Braidy N; Khalil J; Fang Z-M; Xu YH; Chan DKY, 2014, 'Association of leukocyte telomere length with vascular dementia and cancer mortality in an elderly population.', Journal of the American Geriatrics Society, vol. 62, pp. 1384 - 1386, http://dx.doi.org/10.1111/jgs.12910
2014
Braidy N; Poljak A; Grant R; Jayasena T; Mansour H; Chan-Ling T; Guillemin GJ; Smythe G; Sachdev P, 2014, 'Mapping NAD+ metabolism in the brain of ageing Wistar rats: potential targets for influencing brain senescence', Biogerontology, vol. 15, pp. 177 - 198, http://dx.doi.org/10.1007/s10522-013-9489-5
2014
Adams S; Teo C; McDonald KL; Zinger A; Bustamante S; Lim CK; Sundaram G; Braidy N; Brew BJ; Guillemin GJ, 2014, 'Involvement of the Kynurenine Pathway in Human Glioma Pathophysiology', PLOS ONE, vol. 9, http://dx.doi.org/10.1371/journal.pone.0112945
2014
Braidy N; Essa MM; Bridge WB; Subash SS; Manivasagam TM; Vijayan RKV; Al-Adawi SA; Guillemin GG, 2014, 'REVIEW OF NATURAL PRODUCTS ON PARKINSON’S DISEASE PATHOLOGY', Journal of Aging Research & Clinical Practice, vol. 3, pp. 127 - 136
2014
Braidy N; Subash SS; Essa MM; Al-Buraiki ZA; Vaishnav RV; Al-Adawi SA; Al-Asmi SA; Al-Senawi SA; Alobaidy HA; Lakhtakia RL; Guillemin GJ, 2014, 'NEUROPROTECTIVE EFFECTS OF A VARIETY OF POMEGRANATE JUICE EXTRACTS (PJE) AGAINST THE EXCITOTOXIN QUINOLINIC ACID IN HUMAN PRIMARY NEURONS', The Journal of Prevention of Alzheimer's disease, vol. 1, pp. 84 - 90, http://dx.doi.org/10.14283/jpad.2014.3
2014
Godoy JA; Rios JA; Zolezzi JM; Braidy N; Inestrosa NC, 2014, 'Signaling pathway cross talk in Alzheimer's disease', Cell Communication and Signaling, vol. 12, http://dx.doi.org/10.1186/1478-811X-12-23
2014
Subash S; Essa M; Al-Asmi A; Al-Adawi S; Vaishnav R; Braidy N; Manivasagam T; Guillemin G, 2014, 'Pomegranate from oman alleviates the brain oxidative damage in transgenic mouse model of alzheimer′s disease', Journal of Traditional and Complementary Medicine, vol. 4, pp. 232 - 238, http://dx.doi.org/10.4103/2225-4110.139107
2014
Braidy N; Gai W-P; Xu YH; Sachdev P; Guillemin GJ; Jiang X-M; Ballard JWO; Horan MP; Fang ZM; Chong BH; Chan DKY, 2014, 'Alpha-Synuclein Transmission and Mitochondrial Toxicity in Primary Human Foetal Enteric Neurons In Vitro', Neurotoxicity Research, vol. 25, pp. 170 - 182, http://dx.doi.org/10.1007/s12640-013-9420-5
2014
Godoy JA; Zolezzi JM; Braidy N; Inestrosa NC, 2014, 'Role of Sirt1 During the Ageing Process: Relevance to Protection of Synapses in the Brain', Molecular Neurobiology, vol. 50, pp. 744 - 756, http://dx.doi.org/10.1007/s12035-014-8645-5
2014
Al-Adawi S; Braidy N; Essa M; Al-Azri F; Hussain S; Al-Sibani N; Al-Khabouri J; Al-Asmi A; Al-Mashani A, 2014, 'Cognitive Profiles in Patients with Multi-Infarct Dementia: An Omani Study', DEMENTIA AND GERIATRIC COGNITIVE DISORDERS EXTRA, vol. 4, pp. 271 - +, http://dx.doi.org/10.1159/000363621
2014
Braidy N; Brew BJ; Inestrosa NC; Chung R; Sachdev P; Guillemin GJ, 2014, 'Changes in Cathepsin D and Beclin-1 mRNA and protein expression by the excitotoxin quinolinic acid in human astrocytes and neurons', Metabolic brain disease, vol. 29, pp. 873 - 883, http://dx.doi.org/10.1007/s11011-014-9557-9
2014
Godoy JA; Arrázola MS; Ordenes D; Silva-Alvarez C; Braidy N; Inestrosa NC, 2014, 'Wnt-5a ligand modulates mitochondrial fission-fusion in rat hippocampal neurons', Journal of Biological Chemistry, vol. 289, pp. 36179 - 36193, http://dx.doi.org/10.1074/jbc.M114.557009
2014
Godoy JA; Zolezzi JM; Braidy N; Inestrosa NC, 2014, 'Role of Sirt1 during the ageing process: relevance to protection of synapses in the brain', Molecular neurobiology, vol. 50, pp. 744 - 756, http://dx.doi.org/10.1007/s12035-014-8645-5
2014
Braidy N; Poljak A; Marjo C; Rutlidge H; Rich A; Jayasena T; Inestrosa NC; Sachdev P, 2014, 'Metal and complementary molecular bioimaging in alzheimer's disease', Frontiers in Aging Neuroscience, vol. 6, http://dx.doi.org/10.3389/fnagi.2014.00138
2014
Chiu AS; Gehringer MM; Braidy N; Guillemin GJ; Welch JH; Neilan BA, 2013, 'Gliotoxicity of the cyanotoxin, â-methyl-amino-L-alanine (BMAA)', Scientific Reports, vol. 3, pp. 1 - 5, http://dx.doi.org/10.1038/srep01482
2013
Jayasena T; Braidy N; Sachdev P; Poljak A; Smythe G; Münch G, 2013, 'The role of polyphenols in the modulation of sirtuins and other pathways involved in Alzheimer's disease', Ageing Research Reviews, vol. 12, pp. 867 - 883, http://dx.doi.org/10.1016/j.arr.2013.06.003
2013
Tamilselvam K; Braidy N; Manivasagam T; Essa MM; Prasad NR; Karthikeyan S; Thenmozhi AJ; Selvaraju S; Guillemin GJ, 2013, 'Neuroprotective effects of hesperidin, a plant flavanone, on rotenone-induced oxidative stress and apoptosis in a cellular model for Parkinson's disease', Oxidative Medicine and Cellular Longevity, http://dx.doi.org/10.1155/2013/102741
2013
Braidy N; Lim CK; Grant R; Brew BJ; Guillemin GJ, 2013, 'Serum nicotinamide adenine dinucleotide levels through disease course in multiple sclerosis', Brain Research, vol. 1537, pp. 267 - 272, http://dx.doi.org/10.1016/j.brainres.2013.08.025
2013
Essa M; Braidy N; Vijayan K; Subash ; Guillemin GJ, 2013, 'Excitotoxicity in the Pathogenesis of Autism', Neurotoxicity Research, vol. 23, pp. 393 - 400, http://dx.doi.org/10.1007/s12640-012-9354-3
2013
Essa M; Braidy N; Waly MI; Al-Farsi Y; Sharbati M; Subash ; Amanat A; Al-shaffae A; Guillemin GJ, 2013, 'Impaired Antioxidant Status and Reduced Energy Metabolism in Autistic Children', Research In Autism Spectrum Disorders, vol. 7, pp. 557 - 565, http://dx.doi.org/10.1016/j.rasd.2012.12.006
2013
Al Asmi A; Al Maniri A; Al-Farsi YM; Burke DT; Al Asfoor FMH; Al Busaidi I; Al Breiki MHA; Lahiri S; Braidy N; Essa MM; Al-Adawi S, 2013, 'Types and sociodemographic correlates of complementary and alternative medicine (CAM) use among people with epilepsy in Oman', Epilepsy and Behavior, vol. 29, pp. 361 - 366, http://dx.doi.org/10.1016/j.yebeh.2013.07.022
2013
Braidy N; Gai WP; Xu YH; Sachdev P; Guillemin GJ; Jiang XM; Ballard JWO; Horan MP; Fang ZM; Chong BH; Chan DKY, 2013, 'Uptake and mitochondrial dysfunction of alpha-synuclein in human astrocytes, cortical neurons and fibroblasts', Translational Neurodegeneration, vol. 2, http://dx.doi.org/10.1186/2047-9158-2-20
2013
Sachdev PS; Zhuang L; Braidy N; Wen W, 2013, 'Is Alzheimer’s a disease of the white matter?', Current Opinion in Psychiatry, vol. 26, pp. 244 - 251, http://dx.doi.org/10.1097/YCO.0b013e32835ed6e8
2013
Braidy N; Selvaraju S; Essa MM; Vaishnav R; Al-Adawi S; Al-Asmi A; Al-Senawi H; Abd Alrahman Alobaidy A; Lakhtakia R; Guillemin GJ, 2013, 'Neuroprotective effects of a variety of pomegranate juice extracts against MPTP-induced cytotoxicity and oxidative stress in human primary neurons', Oxidative Medicine and Cellular Longevity, http://dx.doi.org/10.1155/2013/685909
2013
Essa M; Subash ; Al-adawi ; Braidy N; Lim CK; Manivasagam T; Guillemin GJ, 2013, 'Role of NAD+, Oxidative Stress and Tryptophan Metabolism in Autism Spectrum Disorders', International Journal of Tryptophan Research : IJTR, vol. 6, pp. 1 - 14, http://dx.doi.org/10.4137/IJTR.S11355
2013
Sheipouri D; Braidy N; Guillemin GJ, 2012, 'Kynurenine Pathway in Skin Cells: Implications for UV-Induced Skin Damage', International Journal of Tryptophan Research : IJTR, vol. 5, pp. 15 - 25, http://dx.doi.org/10.4137/IJTR.S9835
2012
Braidy N; Munoz PC; Palacios AG; Castellano-Gonzalez G; Inestrosa NC; Chung RS; Sachdev PS; Guillemin GJ, 2012, 'Recent rodent models for Alzheimer's disease: Clinical implications and basic research', Journal of Neural Transmission, vol. 119, pp. 173 - 195, http://dx.doi.org/10.1007/s00702-011-0731-5
2012
Chiu AS; Gehringer MM; Braidy N; Guillemin GJ; Welch JH; Neilan BA, 2012, 'Excitotoxic potential of the cyanotoxin â-methyl-amino-l-alanine (BMAA) in primary human neurons', Toxicon, vol. 60, pp. 1159 - 1165, http://dx.doi.org/10.1016/j.toxicon.2012.07.169
2012
Massudi H; Grant RS; Braidy N; Guest J; Farnsworth BN; Guillemin GJ, 2012, 'Age-associated changes in oxidative stress and NAD + metabolism in human tissue', PLoS One, vol. 7, pp. e42357, http://dx.doi.org/10.1371/journal.pone.0042357
2012
Adams S; Braidy N; Bess A; Brew BJ; Grant RS; Teo C; Guillemin GJ, 2012, 'The kynurenine pathway in brain tumor pathogenesis', Cancer research, vol. 72, pp. 5649 - 5657, http://dx.doi.org/10.1158/0008-5472.CAN-12-0549
2012
Massudi H; Grant RS; Guillemin GJ; Braidy N, 2012, 'NAD + metabolism and oxidative stress: The golden nucleotide on a crown of thorns', Redox Report, vol. 17, pp. 28 - 46, http://dx.doi.org/10.1179/1351000212Y.0000000001
2012
Essa MM; Vijayan R; Castellano-Gonzalez G; Memon M; Braidy N; Guillemin GJ, 2012, 'Neuroprotective Effect of Natural Products Against Alzheimer's Disease', Neurochemical Research, vol. 37, pp. 1829 - 1842, http://dx.doi.org/10.1007/s11064-012-0799-9
2012
Braidy N; Jayasena T; Poljak A; Sachdev PS, 2012, 'Sirtuins in cognitive ageing and Alzheimer's disease', Current Opinion in Psychiatry, vol. 25, pp. 226 - 230, http://dx.doi.org/10.1097/YCO.0b013e32835112c1
2012
Braidy N; Guillemin GJ; Grant RS, 2011, 'Effects of Kynurenine Pathway Inhibition on NAD+ Metabolism and Cell Viability in Human Primary Astrocytes and Neurons.', International Journal of Tryptophan Research : IJTR, vol. 4, pp. 29 - 37, http://dx.doi.org/10.4137/IJTR.S7052
2011
Braidy N; Guillemin GJ; Hussein M; Chan-Ling T; Poljak A; Grant RS, 2011, 'Age Related Changes in NAD+ Metabolism Oxidative Stress and Sirt1 Activity in Wistar Rats.', PLoS One, vol. 6, pp. e19194, http://dx.doi.org/10.1371/journal.pone.0019194
2011
Adams S; Braidy N; Teo C; Guillemin G, 2011, 'INVOLVEMENT OF THE KYNURENINE PATHWAY IN HUMAN PRIMARY GLIOBLASTOMA PATHOGENESIS', NEURO-ONCOLOGY, vol. 13, pp. 69 - 69, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000297026600283&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2011
Braidy N; Guillemin GJ; Mansour H; Chan-Ling T; Grant RS, 2011, 'Changes in kynurenine pathway metabolism in the brain, liver and kidney of aged female Wistar rats', FEBS Journal, vol. 278, pp. 4425 - 4434, http://dx.doi.org/10.1111/j.1742-4658.2011.08366.x
2011
Braidy N; Bui K; Bajorek B, 2011, 'Evaluating the impact of new anticoagulants in the hospital setting', Pharmacy Practice, vol. 9, pp. 1 - 10, http://dx.doi.org/10.4321/S1886-36552011000100001
2011
Guillemin GJ; Rahman A; Ting K; Cullen KM; Braidy N; Chung RS; Wu W; Brew BJ, 2010, 'INVOLVEMENT OF THE KYNURENINE PATHWAY IN ALZHEIMER'S DISEASE', JOURNAL OF NEUROCHEMISTRY, vol. 115, pp. 39 - 39, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000281812600096&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2010
Braidy N; Grant R; Adams S; Guillemin GJ, 2010, 'Neuroprotective effects of naturally occurring polyphenols on quinolinic acid-induced excitotoxicity in human neurons', FEBS Journal, vol. 277, pp. 368 - 382, http://dx.doi.org/10.1111/j.1742-4658.2009.07487.x
2010
Braidy N; Grant RS; Adams S; Brew BJ; Guillemin GJ, 2009, 'Mechanism for quinolinic acid cytotoxicity in human astrocytes & neurons', Neurotoxicity Research, vol. 16, pp. 77 - 86, http://dx.doi.org/10.1007/s12640-009-9051-z
2009
Rahman A; Ting K; Cullen KM; Braidy N; Brew BJ; Guillemin GJ, 2009, 'The excitotoxin quinolinic acid induces tau phosphorylation in human neurons', PLoS One, vol. 4, pp. e6344 -1 - 15, http://dx.doi.org/10.1371/journal.pone.0006344
2009
Braidy N; Grant RS; Brew BJ; Adams S; Jayasena T; Guillemin GJ, 2009, 'Effects of Kynurenine Pathway Metabolites on Intracellular NAD+ Synthesis and Cell Death in Human Primary Astrocytes and Neurons', International Journal of Tryptophan Research : IJTR, vol. 2, pp. 61 - 69
2009
Braidy N; Guillemin GJ; Grant RS, 2008, 'Promotion of Cellular NAD Anabolism: Therapeutic Potential for Oxidative Stress in Aging & Alzheimer`s Disease', Neurotoxicity Research, vol. 13, pp. 173 - 184, http://dx.doi.org/10.1007/BF03033501
2008
Book Chapters
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Braidy N; Poljak A; Sachdev P, 2019, 'Nicotinamide Adenine Dinucleotide (NAD+) in Aging', in Danan G; Dupre ME (ed.), Encyclopedia of Gerontology and Population Aging, Springer International Publishing, Cham, Switzerland, pp. 1 - 1, http://dx.doi.org/10.1007/978-3-319-69892-2_1035-1
2019
Schultz MB; Lu Y; Braidy N; Sinclair DA, 2018, 'Assays for NAD+-Dependent reactions and NAD+ metabolites', in Chang P (ed.), ADP-ribosylation and NAD+ Utilizing Enzymes. Methods in Molecular Biology, Humana Press, New York, N.Y., pp. 77 - 90, http://dx.doi.org/10.1007/978-1-4939-8588-3_6
2018
Braidy N; Poljak A; Jayasena T; Sachdev PS, 2017, 'Natural Plant-Derived Acetylcholinesterase Inhibitors: Relevance for Alzheimer's Disease', in Andrade PB; Valentao P; Pereira DM (ed.), Natural Products Targeting Clinically Relevant Enzymes, Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany, pp. 297 - 318, http://dx.doi.org/10.1002/9783527805921.ch12
2017
Braidy N; Poljak A; Jayasena T; Sachdev P, 2014, 'Drug treatments for alzheimer's disease: Hopes and challenges', in Handbook of Neurotoxicity, pp. 1173 - 1190, http://dx.doi.org/10.1007/978-1-4614-5836-4_141
2014
Braidy N; Poljak A; Jayasena T; Adams S; Sachdev P, 2014, 'Glutamate in the pathogenesis of gliomas', in Handbook of Neurotoxicity, pp. 1287 - 1298, http://dx.doi.org/10.1007/978-1-4614-5836-4_149
2014
Braidy N; Poljak A; Jayasena T; Guillemin GJ; Sachdev P, 2014, 'Ionotropic receptors in the central nervous system and neurodegenerative disease', in Handbook of Neurotoxicity, pp. 1071 - 1092, http://dx.doi.org/10.1007/978-1-4614-5836-4_126
2014
Essa MM; Braidy N; Subash S; Vijayan RK; Guillemin GJ, 2014, 'Excitotoxicity in the pathogenesis of autism', in Handbook of Neurotoxicity, pp. 1267 - 1271, http://dx.doi.org/10.1007/978-1-4614-5836-4_148
2014
Marcal H; Wanandy NS; Castellano-Gonzalez G; Braidy N; Guillemin GJ, 2012, 'Curcumin: Medicinal Properties, Molecular Targets and Biological Mechanisms', in Sasaki J; Kichida M (ed.), Curcumin: Biosynthesis, Medicinal Uses and Health Benefits, Nova, pp. 133 - 154, https://www.novapublishers.com/catalog/product_info.php?products_id=30913&osCsid=;%20https://www.novapublishers.com/catalog/product_info.php?products_id=35977
2012
Conference Abstracts
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Virk GK; Poljak A; Braidy N; Sachdev PS, 2019, 'Method development and proteomic analysis of depleted plasma for biomarker discovery in neurodegenerative diseases [Poster Abstract P2-219].S', in Alzheimer's & Dementia, Elsevier BV, Los Angeles, CA, USA, Vol. 15, pp. P661 - P661, presented at Alzheimer's Association International Conference (AAIC) 2019, Los Angeles, CA, USA, 14 July 2019 - 16 July 2019, http://dx.doi.org/10.1016/j.jalz.2019.06.2626
2019
Liu Y; Braidy N; Sachdev PS, 2018, 'Plasma lipidomics of vascular dementia [Abstact P3-259]', in Alzheimer's & Dementia, Elsevier BV, Chicago, USA, Vol. 14, pp. P1174 - P1174, presented at Alzheimer’s Association International Conference (AAIC) 2018, Chicago, USA, 22 July 2018 - 26 July 2018, http://dx.doi.org/10.1016/j.jalz.2018.06.1619
2018
Virk GK; Poljak A; Braidy N; Sachdev PS, 2018, 'CSF and blood biomarkers of early-onset Alzheimer’s disease: a systematic review and meta-analysis [Poster Abstract P3-226]', in Alzheimer's & Dementia, Elsevier BV, Chicago, USA, Vol. 14, pp. P1158 - P1158, presented at Alzheimer’s Association International Conference (AAIC) 2018, Chicago, USA, 22 July 2018 - 26 July 2018, http://dx.doi.org/10.1016/j.jalz.2018.06.1585
2018
Braidy N; Poljak A; Marjo C; Rutlidge H; Rich A; Inestrosa N; Sachdev PS, 2017, 'Identification of Cerebral Metal Ion Imbalance in the Brain of Ageing Octodon Degu: a Natural Model for Alzheimer's Disease [Poster Abstract P2-080]', in Alzheimer's and Dementia, Elsevier, London, UK, Vol. 13, pp. P636 - P637, presented at Alzheimer's Association International Conference (AAIC) 2017, London, UK, 16 July 2017 - 20 July 2017, http://dx.doi.org/10.1016/j.jalz.2017.06.729
2017
Poljak A; Braidy N; Maclean C; Shepherd C; Raftery MJ; Sachdev PS, 2017, 'Proteomics of the Alzheimer's disease brain: Neuropathology and neuroresilience [Poster Abstract P2-155]', in Alzheimer's and Dementia, Elsevier, London, UK, Vol. 13, pp. P667 - P667, presented at Alzheimer's Association International Conference (AAIC) 2017, London, UK, 16 July 2017 - 20 July 2017, http://dx.doi.org/10.1016/j.jalz.2017.06.806
2017
Jayasena T; Poljak A; Bustamante S; Braidy N; Raftery MJ; Sachdev PS, 2017, 'Sirtuin protein and related energy metabolite changes in the Alzheimer brain [Poster Abstract P2-182]', in Alzheimer's and Dementia, Elsevier, London, UK, Vol. 13, pp. P676 - P676, presented at lzheimer's Association International Conference (AAIC) 2017, London, UK, 16 July 2017 - 20 July 2017, http://dx.doi.org/10.1016/j.jalz.2017.06.833
2017
Jugder B; Ertan H; Braidy N; Lee M; Manefield M; Marquis CP, 2016, 'Transcriptomic and proteomic studies of Dehalobacter UNSWDHB reveal major changes during its organohalide respiration', in American Society of Microbiology Microbe, American Society of Microbiology Microbe, Boston, US, presented at American Society of Microbiology Microbe, Boston, US
2016
Braidy N; Poljak A; Zarka M; Bridge W; Sachdev P, 2013, 'γ-glutamylcysteine (GGC)-mediated upregulation of glutathione levels can ameliorate toxicity of natural beta-amyloid oligomers in primary adult human neurons [Abstract P4-332]', in Alzheimer's & Dementia, Alzheimer’s Association International Conference (AAIC) 2013, Boston, MA, USA, Vol. 9, pp. P854 - P854, presented at Alzheimer’s Association International Conference (AAIC) 2013, Boston, MA, USA, 13 July 2013 - 18 July 2013, http://dx.doi.org/10.1016/j.jalz.2013.08.166
2013
Jayasena T; Poljak A; Zhong L; Braidy N; Smythe G; Raftery M; Sachdev P, 2013, 'Development of a targeted mass spectrometry method for accurate quantification of human sirtuins in biological samples [Abstract P2-035]', in Alzheimer's & Dementia, Alzheimer’s Association International Conference (AAIC) 2013, Boston, MA, USA, Vol. 9, pp. P357 - P357, presented at Alzheimer’s Association International Conference (AAIC) 2013, Boston, MA, USA, 13 July 2013 - 18 July 2013, http://dx.doi.org/10.1016/j.jalz.2013.05.677
2013
Braidy N; Poljak A; Jayasena T; Guillemin G; Smythe G; Sachdev P, 2012, 'NAD+ metabolism, and oxidative stress in the brain of aging Wistar rats: Is there a link? [Abstract P3-073]', in Alzheimer's & Dementia, Alzheimer’s Association International Conference (AAIC) 2012, Vancouver, Canada, Vol. 8, pp. P478 - P478, presented at Alzheimer’s Association International Conference (AAIC) 2012, Vancouver, Canada, 14 July 2012 - 19 July 2012, http://dx.doi.org/10.1016/j.jalz.2012.05.1292
2012
Braidy N; Jayasena T; Poljak A; Smythe G; Guillemin G; Sachdev P, 2012, 'Sirtuin expression during aging and in Alzheimer's disease [Abstract P2-094]', in Alzheimer's & Dementia, Alzheimer’s Association International Conference (AAIC) 2012, Vancouver, Canada, Vol. 8, pp. P295 - P296, presented at Alzheimer’s Association International Conference (AAIC) 2012, Vancouver, Canada, 14 July 2012 - 19 July 2012, http://dx.doi.org/10.1016/j.jalz.2012.05.798
2012
Books
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Braidy N, 2015, Pomegranates: Old age remedy for today's diseases
2015
Conference Papers
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Adams S; Teo C; McDonald KL; Zinger A; Bustamante S; Lim CK; Sundaram G; Braidy N; Brew BJ; Guillemin GJ, 2014, 'Involvement of the kynurenine pathway in human glioma pathophysiology', in PLoS ONE, http://dx.doi.org/10.1371/journal.pone.0112945
2014
Subash S; Braidy N; Essa M; Al-Adawi S; Al-Asmi A; Vaishnav R; Guillemin G, 2014, 'Pomegranate ameliorates Alzheimer's disease-type neurodegeneration in tg 2576 mouse model', in FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, San Diego, CA, presented at Experimental Biology Meeting, San Diego, CA, 26 April 2014 - 30 April 2014, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000346646705152&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2014
Conference Posters
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Braidy N; Poljak A; Jayasena T; Mansour H; Chan-Ling T; Guillemin GJ; Smythe G; Sachdev PS, 2012, 'Differential expression of sirtuins in the aging rat brain [Poster]', Vancouver, Canada, presented at Alzheimer’s Association International Conference (AAIC) 2012, Vancouver, Canada, 14 July 2012 - 19 July 2012
2012