Michelle Farrar

Associate Professor

Michelle Farrar is an Associate Professor in Paediatric Neurology at UNSW Sydney and specialist child neurologist at Sydney Children’s Hospital, leading the Neuromuscular clinical and research programs.

Michelle’s team is focused on developing and translating innovative ways of providing the best possible care from the time of diagnosis, through treatment and beyond to people with neuromuscular, neurodevelopmental or rare neurogenetic diseases. The research program also integrates interdisciplinary genomics research, together with community and consumer involvement.

Current roles include:

  • Lead, Neuromuscular Diseases Clinical and Research Program, Sydney Children’s Hospital.
  • Research lead (Clinical Neurology) NSW/ACT Newborn Screening Pilot for neuromuscular disorders

 

Society Memberships & Professional Activities:

  • Member of the Australian and New Zealand Association of Neurologists
  • Member of the Australia and New Zealand Child Neurology Society
  • Fellow of the Royal Australasian College of Physicians
  • Treat NMD Neuromuscular Network
  • Australian and New Zealand Association of Neurologists Educational and Training EEG and Clinical Neurophysiology Committee member
  • Australian and New Zealand Child Neurology Society, Scientific meeting organising committee member (2019)
  • Australian Neuromuscular Network Clinical Care Steering Group
  • Sydney Children’s Hospital Scientific Advisory Committee member for the Human Research Ethics Committee
  • Australian Neuromuscular Diseases Registry, clinical lead for SMA and advisory committee member
  • Neurodevelopment Australia, Steering Committee member
  • Motor Neurone Diseases Research Institute of Australia Beryl Bayley Postdoctoral Fellow (2016-2019)
Journal articles
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Wan HWY; Carey KA; D'Silva A; Vucic S; Kiernan MC; Kasparian NA; Farrar MA, 2020, 'Health, wellbeing and lived experiences of adults with SMA: a scoping systematic review.', Orphanet J Rare Dis, vol. 15, pp. 70, http://dx.doi.org/10.1186/s13023-020-1339-3
2020
Stelzer-Braid S; Wynn M; Chatoor R; Scotch M; Ramachandran V; Teoh HL; Farrar MA; Sampaio H; Andrews PI; Craig ME; MacIntyre CR; Varadhan H; Kesson A; Britton PN; Newcombe J; Rawlinson WD, 2020, 'Next generation sequencing of human enterovirus strains from an outbreak of enterovirus A71 shows applicability to outbreak investigations', Journal of Clinical Virology, vol. 122, pp. 104216 - 104216, http://dx.doi.org/10.1016/j.jcv.2019.104216
2020
Kandula T; Farrar MA; Cohn RJ; Carey KA; Johnston K; Kiernan MC; Krishnan AV; Park SB, 2020, 'Changes in long term peripheral nerve biophysical properties in childhood cancer survivors following neurotoxic chemotherapy', Clinical Neurophysiology, vol. 131, pp. 783 - 790, http://dx.doi.org/10.1016/j.clinph.2019.12.411
2020
Kariyawasam DST; Russell JS; Wiley V; Alexander IE; Farrar MA, 2019, 'The implementation of newborn screening for spinal muscular atrophy: the Australian experience', Genetics in Medicine, http://dx.doi.org/10.1038/s41436-019-0673-0
2019
Kariyawasam DST; D’silva A; Lin C; Ryan MM; Farrar MA, 2019, 'Biomarkers and the development of a personalized medicine approach in spinal muscular atrophy', Frontiers in Neurology, vol. 10, http://dx.doi.org/10.3389/fneur.2019.00898
2019
Paguinto SG; Kasparian NA; Bray P; Farrar M, 2019, 'Parents’ perceptions of power wheelchair prescription for children with a neuromuscular disorder: a scoping review', Disability and Rehabilitation, vol. 41, pp. 2750 - 2757, http://dx.doi.org/10.1080/09638288.2018.1474496
2019
Banuelos R; Beavis E; Le Marne F; Rowe N; Gao Y; Menzies J; Farrar MA; Cardamone M, 2019, 'Factors Affecting the Efficacy, Tolerability and Compliance of Dietary Therapy for Epilepsy- Four-Years Experience', Neurological Case Reports, vol. 2, pp. 1010 - 1010
2019
Wan HWY; Carey KA; D'Silva A; Kasparian NA; Farrar MA, 2019, '"Getting ready for the adult world": How adults with spinal muscular atrophy perceive and experience healthcare, transition and well-being', Orphanet Journal of Rare Diseases, vol. 14, http://dx.doi.org/10.1186/s13023-019-1052-2
2019
Jones HF; Bryen SJ; Waddell LB; Bournazos A; Davis M; Farrar MA; McLean CA; Mowat DR; Sampaio H; Woodcock IR; Ryan MM; Jones KJ; Cooper ST, 2019, 'Importance of muscle biopsy to establish pathogenicity of DMD missense and splice variants', Neuromuscular Disorders, vol. 29, pp. 913 - 919, http://dx.doi.org/10.1016/j.nmd.2019.09.013
2019
Cornett KMD; Wojciechowski E; Sman AD; Walker T; Menezes MP; Bray P; Halaki M; Burns J; Sman D; Mandarakas MR; Rose KJ; Bray P; Baldwin J; McKay MJ; Refshauge KM; Raymond J; Walker T; Sampaio H; Mudge A; Purcell L; Miller C; Gray K; Harman M; Gabrael N; Ouvrier RA; Farrar M; Sman A, 2019, 'Magnetic resonance imaging of the anterior compartment of the lower leg is a biomarker for weakness, disability, and impaired gait in childhood Charcot–Marie–Tooth disease', Muscle and Nerve, vol. 59, pp. 213 - 217, http://dx.doi.org/10.1002/mus.26352
2019
Donkervoort S; Sabouny R; Yun P; Gauquelin L; Chao KR; Hu Y; Al Khatib I; Töpf A; Mohassel P; Cummings BB; Kaur R; Saade D; Moore SA; Waddell LB; Farrar MA; Goodrich JK; Uapinyoying P; Chan SHS; Javed A; Leach ME; Karachunski P; Dalton J; Medne L; Harper A; Thompson C; Thiffault I; Specht S; Lamont RE; Saunders C; Racher H; Bernier FP; Mowat D; Witting N; Vissing J; Hanson R; Coffman KA; Hainlen M; Parboosingh JS; Carnevale A; Yoon G; Schnur RE; Boycott KM; Mah JK; Straub V; Foley AR; Innes AM; Bönnemann CG; Shutt TE, 2019, 'MSTO1 mutations cause mtDNA depletion, manifesting as muscular dystrophy with cerebellar involvement', Acta Neuropathologica, vol. 138, pp. 1013 - 1031, http://dx.doi.org/10.1007/s00401-019-02059-z
2019
Paguinto SG; Kasparian NA; Bray P; Farrar M, 2019, '“It’s not just the wheelchair, it’s everything else”: Australian parents’ perspectives of wheelchair prescription for children with neuromuscular disorders', Disability and Rehabilitation, pp. 1 - 10, http://dx.doi.org/10.1080/09638288.2019.1595749
2019
Darras BT; Farrar MA; Mercuri E; Finkel RS; Foster R; Hughes SG; Bhan I; Farwell W; Gheuens S, 2019, 'An Integrated Safety Analysis of Infants and Children with Symptomatic Spinal Muscular Atrophy (SMA) Treated with Nusinersen in Seven Clinical Trials', CNS Drugs, vol. 33, pp. 919 - 932, http://dx.doi.org/10.1007/s40263-019-00656-w
2019
Mandarakas MR; Menezes MP; Rose KJ; Shy R; Eichinger K; Foscan M; Estilow T; Kennedy R; Herbert K; Bray P; Refshauge K; Ryan MM; Yiu EM; Farrar M; Sampaio H; Moroni I; Pagliano E; Pareyson D; Yum SW; Herrmann DN; Acsadi G; Shy ME; Burns J; Sanmaneechai O, 2019, 'Erratum to: Development and validation of the Charcot-Marie-Tooth Disease Infant Scale', Brain : a journal of neurology, vol. 142, pp. e14, http://dx.doi.org/10.1093/brain/awy332
2019
Mandarakas MR; Menezes MP; Rose KJ; Shy R; Eichinger K; Foscan M; Estilow T; Kennedy R; Herbert K; Bray P; Refshauge K; Ryan MM; Yiu EM; Farrar M; Sampaio H; Moroni I; Pagliano E; Pareyson D; Yum SW; Herrmann DN; Acsadi G; Shy ME; Burns J; Sanmaneechai O, 2018, 'Development and validation of the Charcot-Marie-Tooth disease infant scale', Brain, vol. 141, pp. 3319 - 3330, http://dx.doi.org/10.1093/brain/awy280
2018
Oates E; Jones K; Donkervoort S; Charlton A; Brammah S; Smith J; Ware J; Yau K; Swanson L; Whiffin N; Peduto A; Bournazos A; Waddell L; Farrar M; Sampaio H; Teoh H; Lamont P; Mowat D; Fitzsimmons R; Corbett A; Ryan M; O'Grady G; Sandaradura S; Ghaoui R; Joshi H; Marshall J; Nolan M; Kaur S; Punetha J; Topf A; Harris E; Bakshi M; Genetti C; Marttila M; Werkauff U; Streichenberger N; Pestronk A; Mazanti I; Pinner J; Vuillerot C; Grosmann C; Camacho A; Mohassel P; Leach M; Foley A; Bharucha-Goeber D; Collins J; Connolly A; Gilbreath H; Iannaccone S; Castro D; Cummings B; Webster R; Lazaro L; Vissing J; Coppens S; Deconinck N; Luk H; Thomas N; Foulds N; Illingworth M; Ellard S; McLean C; Phadke R; Ravenscroft G; Witting N; Hackman P; Clarke N; Lek M; Beggs A; Bonnemann C; MacArthur D; Granzier H; Davis M; Laing N, 2018, 'Congenital titinopathy: comprehensive characterisation & pathogenic insights', Annals or Neurology, vol. 83, pp. 1105 - 1124, http://dx.doi.org/10.1002/ana.25241
2018
Ho G; Carey K; Cardamone M; Farrar M, 2018, 'Myotonic dystrophy type 1: clinical manifestations in children and adolescents', Archives of Disease in Childhood, vol. 104, pp. 48 - 52, http://dx.doi.org/10.1136/archdischild-2018-314837
2018
Palmer EE; Schofield D; Shrestha R; Kandula T; Macintosh R; Lawson JA; Andrews I; Sampaio H; Johnson AM; Farrar MA; Cardamone M; Mowat D; Elakis G; Lo W; Zhu Y; Ying K; Morris P; Tao J; Dias KR; Buckley M; Dinger ME; Cowley MJ; Roscioli T; Kirk EP; Bye A; Sachdev RK, 2018, 'Integrating exome sequencing into a diagnostic pathway for epileptic encephalopathy: Evidence of clinical utility and cost effectiveness', Molecular Genetics and Genomic Medicine, vol. 6, pp. 186 - 199, http://dx.doi.org/10.1002/mgg3.355
2018
Farrar MA; Carey KA; Paguinto SG; Chambers G; Kasparian NA, 2018, 'Financial, opportunity and psychosocial costs of spinal muscular atrophy: an exploratory qualitative analysis of Australian carer perspectives.', BMJ Opem, vol. 8, pp. e020907, http://dx.doi.org/10.1136/bmjopen-2017-020907
2018
Chen KA; Farrar MA; Cardamone M; Lawson J, 2018, 'Cannabis for paediatric epilepsy: challenges and conundrums', The Medical journal of Australia, vol. 208, pp. 138 - 142, http://dx.doi.org/10.5694/mja17.00699
2018
Kariyawasam D; Carey K; Jones K; Farrar MA, 2018, 'New and developing therapies in spinal muscular atrophy', Paediatric Respiratory Reviews, vol. 28, pp. 3 - 10, http://dx.doi.org/10.1016/j.prrv.2018.03.003
2018
Fitzgerald DA; Abel F; Jones KJ; Farrar MA, 2018, 'Spinal muscular atrophy: A modifiable disease emerges', Paediatric Respiratory Reviews, vol. 28, pp. 1 - 2, http://dx.doi.org/10.1016/j.prrv.2018.07.001
2018
Kandula T; Farrar MA; Cohn R; Mizrahi D; Carey K; Johnston K; Kiernan M; Krishnan A; Park SB, 2018, 'Chemotherapy induced peripheral neuropathy in long-term survivors of childhood cancer: neurophysiological, functional and patient reported outcomes.', JAMA Neurology, vol. 75, pp. 980 - 988, http://dx.doi.org/10.1001/jamaneurol.2018.0963
2018
Sampaio H; Wilcken B; Farrar M, 2018, 'Screening for spinal muscular atrophy', The Medical journal of Australia, vol. 209, pp. 147 - 148, http://dx.doi.org/10.5694/mja17.00772
2018
Farrar MA; Teoh HL; Carey KA; Cairns A; Forbes R; Herbert K; Holland S; Jones KJ; Menezes MP; Morrison M; Munro K; Villano D; Webster R; Woodcock IR; Yiu EM; Sampaio H; Ryan MM, 2018, 'Nusinersen for SMA: expanded access programme', Journal of Neurology, Neurosurgery and Psychiatry, vol. 89, pp. 937 - 942, http://dx.doi.org/10.1136/jnnp-2017-317412
2018
Chen KA; Farrar M; Cardamone M; Gill D; Smith R; Cowell CT; Truong L; Lawson JA, 2018, 'Cannabidiol for treating drug-resistant epilepsy in children: The New South Wales experience', Medical Journal of Australia, vol. 209, pp. 217 - 221, http://dx.doi.org/10.5694/mja18.00023
2018
Kandula T; Farrar MA; Krishnan AV; Murray J; Timmins HC; Goldstein D; Lin CSY; Kiernan MC; Park SB, 2018, 'Multimodal quantitative examination of nerve function in colorectal cancer patients prior to chemotherapy', Muscle and Nerve, vol. 57, pp. 615 - 621, http://dx.doi.org/10.1002/mus.25968
2018
Burns J; Sman AD; Cornett KMD; Wojciechowski E; Walker T; Menezes MP; Mandarakas MR; Rose KJ; Bray P; Sampaio H; Farrar M; Refshauge KM; Raymond J; Baldwin J; McKay MJ; Mudge A; Purcell L; Miller C; Gray K; Harman M; Gabrael N; Ouvrier RA, 2017, 'Safety and efficacy of progressive resistance exercise for Charcot-Marie-Tooth disease in children: a randomised, double-blind, sham-controlled trial', The Lancet Child and Adolescent Health, vol. 1, pp. 106 - 113, http://dx.doi.org/10.1016/S2352-4642(17)30013-5
2017
Finkel RS; Mercuri E; Darras BT; Connolly AM; Kuntz NL; Kirschner J; Chiriboga CA; Saito K; Servais L; Tizzano E; Topaloglu H; Tulinius M; Montes J; Glanzman AM; Bishop K; Zhong ZJ; Gheuens S; Bennett CF; Schneider E; Farwell W; De Vivo DC; Bradley WG; Schroth MK; Bodensteriner JB; Davis CS; Shell R; Hen J; Austin ED; Aziz-Zaman S; Cappell J; Constantinescu A; Cruz R; Dastgir J; Dunaway S; Engelstad K; Gormley M; Holuba La Marca N; Khandji A; Kramer S; Marra J; Ortiz-Miller C; Popolizio M; Salazar R; Sanabria L; Weimer L; Anand P; Gadeken R; Golumbek PT; Siener C; Zaidman CM; Al-Ghamdi F; Berde C; Ghosh P; Graham R; Harrington T; Koka A; Laine R; Liew W; Mirek E; Ordonez G; Pasternak A; Quigley J; Sethna N; Souris M; Szelag H; Wand L; Day JW; D'Souza G; Duong TT; Gee R; Kitsuwa-Lowe J; McFall D; Patnaik S; Paulose S; Perez J; Proud C; Purse B; Ramamurthi RJ; Sakamuri S; Sampson J; Sanjanwala B; Tesi Rocha AC; Watson K; Welsh L; Pena LDM; Case L; Coates J; DeArmey S; Homi MM; Milleson C; Nelson N; Ross A; Smith E; Taicher B; Wootton J; Finanger E; Benjamin D; Frank A; Roberts C; Russman B, 2017, 'Nusinersen versus sham control in infantile-onset spinal muscular atrophy', New England Journal of Medicine, vol. 377, pp. 1723 - 1732, http://dx.doi.org/10.1056/NEJMoa1702752
2017
Farrar MA; Park SB; Vucic S; Carey KA; Turner BJ; Gillingwater TH; Swoboda KJ; Kiernan MC, 2017, 'Emerging therapies and challenges in spinal muscular atrophy', Annals of Neurology, vol. 81, pp. 355 - 368, http://dx.doi.org/10.1002/ana.24864
2017
Kandula T; Farrar MA; Kiernan MC; Krishnan AV; Goldstein D; Horvath L; Grimison P; Boyle F; Baron-Hay S; Park SB, 2017, 'Neurophysiological and clinical outcomes in chemotherapy-induced neuropathy in cancer', Clinical Neurophysiology, vol. 128, pp. 1166 - 1175, http://dx.doi.org/10.1016/j.clinph.2017.04.009
2017
Farrar MA; Lee MJ; Howells J; Andrews PI; Lin CSY, 2017, 'Burning pain: Axonal dysfunction in erythromelalgia', Pain, vol. 158, pp. 900 - 911, http://dx.doi.org/10.1097/j.pain.0000000000000856
2017
Ho G; Widger J; Cardamone M; Farrar MA, 2017, 'Quality of life and excessive daytime sleepiness in children and adolescents with myotonic dystrophy type 1', Sleep Medicine, vol. 32, pp. 92 - 96, http://dx.doi.org/10.1016/j.sleep.2016.12.005
2017
Teoh HL; Carey K; Sampaio H; Mowat D; Roscioli T; Farrar M, 2017, 'Inherited Paediatric Motor Neuron Disorders: Beyond Spinal Muscular Atrophy', Neural Plasticity, vol. 2017, http://dx.doi.org/10.1155/2017/6509493
2017
Stoll M; Teoh H; Lee J; Reddel S; Zhu Y; Buckley M; Sampaio H; Roscioli T; Farrar M; Nicholson G, 2016, 'Novel motor phenotypes in patients with VRK1 mutations without pontocerebellar hypoplasia', Neurology, vol. 87, pp. 65 - 70, http://dx.doi.org/10.1212/WNL.0000000000002813
2016
Perera N; Sampaio H; Woodhead H; Farrar M, 2016, 'Fracture in Duchenne Muscular Dystrophy: Natural History and Vitamin D Deficiency', Journal of Child Neurology, vol. 31, pp. 1181 - 1187, http://dx.doi.org/10.1177/0883073816650034
2016
Farrar MA; Ho G; Widger J; Cardamone M, 2016, 'Quality of life and excessive daytime sleepiness in children and adolescents with Myotonic dystrophy type 1', Sleep Medicine, vol. 32, pp. 92 - 96, http://dx.doi.org/10.1016/j.sleep.2016.12.005
2016
Teoh HL; Mohammad SS; Britton PN; Kandula T; Lorentzos MS; Booy R; Jones CA; Rawlinson W; Ramachandran V; Rodriguez ML; Ian Andrews P; Dale RC; Farrar MA; Sampaio H, 2016, 'Clinical characteristics and functional motor outcomes of enterovirus 71 neurological disease in children', JAMA Neurology, vol. 73, pp. 300 - 307, http://dx.doi.org/10.1001/jamaneurol.2015.4388
2016
Teoh HL; Solyom A; Schuchman EH; Mowat D; Roscioli T; Farrar M; Sampaio H, 2016, 'Polyarticular arthritis and spinal muscular atrophy in acid ceramidase deficiency', Pediatrics, vol. 138, http://dx.doi.org/10.1542/peds.2016-1068
2016
Menezes MP; Farrar MA; Webster R; Antony J; O'Brien K; Ouvrier R; Kiernan MC; Burns J; Vucic S, 2016, 'Pathophysiology of motor dysfunction in a childhood motor neuron disease caused by mutations in the riboflavin transporter', Clinical Neurophysiology, vol. 127, pp. 911 - 918, http://dx.doi.org/10.1016/j.clinph.2015.05.012
2016
Farrar MA; Vucic S; Nicholson G; Kiernan MC, 2016, 'Motor cortical dysfunction develops in spinocerebellar ataxia type 3', Clinical Neurophysiology, vol. 127, pp. 3418 - 3424, http://dx.doi.org/10.1016/j.clinph.2016.09.005
2016
Menezes MP; Rahman S; Bhattacharya K; Clark D; Christodoulou J; Ellaway C; Farrar M; Pitt M; Sampaio H; Ware TL; Wedatilake Y; Thorburn DR; Ryan MM; Ouvrier R, 2016, 'Neurophysiological profile of peripheral neuropathy associated with childhood mitochondrial disease', Mitochondrion, vol. 30, pp. 162 - 167, http://dx.doi.org/10.1016/j.mito.2016.07.014
2016
Kandula T; Park SB; Cohn RJ; Krishnan AV; Farrar MA, 2016, 'Pediatric chemotherapy induced peripheral neuropathy: A systematic review of current knowledge', Cancer Treatment Reviews, vol. 50, pp. 118 - 128, http://dx.doi.org/10.1016/j.ctrv.2016.09.005
2016
Teoh HL; Sampaio H; Roscioli T; Farrar M, 2016, 'Approaches to genetic diagnosis in neuromuscular conditions in the era of next generation sequencing', Journal of Neurology, Neurosurgery and Psychiatry, vol. 87, pp. 1384 - 1385, http://dx.doi.org/10.1136/jnnp-2016-313812
2016
Farrar MA; Teoh HL; Brammah S; Roscioli T; Cardamone M, 2016, 'Glial mitochondropathy in infantile neuroaxonal dystrophy: Pathophysiological and therapeutic implications', Brain, vol. 139, pp. e67, http://dx.doi.org/10.1093/brain/aww174
2016
Chew K; Carey K; Ho G; Mallitt KA; Widger J; Farrar M, 2016, 'The relationship of body habitus and respiratory function in Duchenne muscular dystrophy', Respiratory Medicine, vol. 119, pp. 35 - 40, http://dx.doi.org/10.1016/j.rmed.2016.08.018
2016
Farrar MA; brewer M; Chaudhry R; Qi J; Kidambi A; Drew A; Menezes M; Ryan M; Mowat D; Subramanian G; Young H; Zuchner S; Reddel S; Nicholson G; Kennerson M, 2016, 'Whole Genome Sequencing Identifies a 78 kb Insertion from Chromosome 8 as the Cause of Charcot-Marie-Tooth Neuropathy CMTX3', PLoS Genetics, vol. 12, http://dx.doi.org/10.1371/journal.pgen.1006177
2016
Ho G; Cardamone M; Farrar M, 2015, 'Congenital and childhood myotonic dystrophy: Current aspects of disease and future directions.', World J Clin Pediatr, vol. 4, pp. 66 - 80, http://dx.doi.org/10.5409/wjcp.v4.i4.66
2015
Farrar MA; Kiernan MC, 2015, 'The Genetics of Spinal Muscular Atrophy: Progress and Challenges', Neurotherapeutics, vol. 12, pp. 290 - 302, http://dx.doi.org/10.1007/s13311-014-0314-x
2015
Teoh HL; Sampaio H; Farrar M, 2015, 'Enterovirus 71 Neuroimaging: “The New Polio of the 21st Century”', Pediatrics & Therapeutics, vol. 05, http://dx.doi.org/10.4172/2161-0665.1000i111
2015
Michelle Farrar NP, 2015, 'Bone Health in Children with Duchenne Muscular Dystrophy: A Review', Pediatrics & Therapeutics, vol. 05, http://dx.doi.org/10.4172/2161-0665.1000252
2015
Farrar MA; Park SB; Krishnan AV; Kiernan MC; Lin CSY, 2014, 'Axonal dysfunction, dysmyelination, and conduction failure in hereditary neuropathy with liability to pressure palsies', Muscle and Nerve, vol. 49, pp. 858 - 865, http://dx.doi.org/10.1002/mus.24085
2014
Farrar MA; Park SB; Lin CS-Y; Kiernan MC, 2013, 'Evolution of peripheral nerve function in humans: Novel insights from motor nerve excitability', The Journal of Physiology, vol. 591, pp. 273 - 286, http://dx.doi.org/10.1113/jphysiol.2012.240820
2013
Gupta VA; Ravenscroft G; Shaheen R; Todd EJ; Swanson LC; Shiina M; Ogata K; Hsu C; Clarke NF; Darras BT; Farrar MA; Hashem A; Manton ND; Muntoni F; North KN; Sandaradura SA; Nishino I; Hayashi YK; Sewry CA; Thompson EM; Yau KS; Brownstein CA; Yu TW; Allcock RJN; Davis MR; Wallgren-Pettersson C; Matsumoto N; Alkuraya FS; Laing NG; Beggs AH, 2013, 'Identification of KLHL41 mutations implicates BTB-Kelch-mediated ubiquitination as an alternate pathway to myofibrillar disruption in nemaline myopathy', American Journal of Human Genetics, vol. 93, pp. 1108 - 1117, http://dx.doi.org/10.1016/j.ajhg.2013.10.020
2013
Farrar M; Vucic O; Johnston H; du Sart D; Kiernan MC, 2013, 'Pathophysiological Insights Derived by Natural History and Motor Function of Spinal Muscular Atrophy.', Journal of Pediatrics, vol. 162, pp. 155 - 159, http://dx.doi.org/10.1016/j.jpeds.2012.05.067
2013
Lin CSY; Farrar MA, 2013, 'No gain - No pain?', Journal of Neurology, Neurosurgery and Psychiatry, vol. 84, pp. 364, http://dx.doi.org/10.1136/jnnp-2012-304098
2013
Michot C; Hubert L; Romero NB; Gouda AS; Mamoune A; Mathew SJ; Kirk EP; Viollet L; Rahman S; Bekri S; Peters HL; McGill J; Glamuzina E; Farrar MA; Von der hagen M; Alexander I; Kirmse B; Barth M; Laforet P; Benlian P; Munnich A; Elpeleg ON; Pines O; Delahodde A; De keyzer Y; De lonlay P, 2012, 'Study of LPIN1, LPIN2 and LPIN3 in rhabdomyolysis and exercise-induced myalgia', Journal of Inherited Metabolic Disease, vol. 35, pp. 1119 - 1128, http://dx.doi.org/10.1007/s10545-012-9461-6
2012
Farrar M; Vucic O; Johnston H; Kiernan MC, 2012, 'Corticomotoneuronal Integrity and Adaption in Spinal Muscular Atrophy', Archives of Neurology, vol. 69, pp. 467 - 473, http://dx.doi.org/10.1001/archneurol.2011.1697
2012
Farrar M; Vucic O; Lin CS-Y; Park SB; Johnston H; Bostock H; Kiernan MC, 2011, 'Dysfunction of axonal membrane conductances in adolescents and young adults with spinal muscular atrophy', Brain, vol. 134, pp. 3185 - 3197, http://dx.doi.org/10.1093/brain/awr229
2011
Farrar M; Lin CS-Y; Krishnan AV; Park SB; Andrews PI; Kiernan MC, 2010, 'Acute, reversible axonal energy failure during stroke-like episodes in MELAS', Pediatrics, vol. 126, pp. e734 - e739, http://dx.doi.org/10.1542/peds.2009-2930
2010
Farrar MA; Johnston HM; Grattan-Smith P; Turner A; Kiernan MC, 2009, 'Spinal muscular atrophy: Molecular mechanisms', Current Molecular Medicine, vol. 9, pp. 851 - 862, http://dx.doi.org/10.2174/156652409789105516
2009
Bye AM; Connolly AM; Farrar MA; Lawson JA; Lonergan A, 2009, 'Teaching paediatric epilepsy to medical students: A randomised crossover trial', Journal of Paediatrics and Child Health (Vol. 48, Suppl. 2, 2012, 1–13), vol. 45, pp. 727 - 730, http://dx.doi.org/10.1111/j.1440-1754.2009.01602.x
2009
Farrar MA; Connolly AM; Lawson JS; Burgess AJ; Lonergan A; Bye AM, 2008, 'Teaching doctors how to diagnose paroxysmal events: a comparison of two educational methods', Medical Education, vol. 42, pp. 909 - 914, http://dx.doi.org/10.1111/j.1365-2923.2008.03146.x
2008
Conference Abstracts
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Finkel RS; Castro D; Farrar MA; Tulinius M; Krosschell KJ; Saito K; Zhang Y; Bhan I; Farwell W; Reyna SP, 2019, 'Interim Report on the Safety and Efficacy of Longer-Term Treatment With Nusinersen in Infantile-Onset Spinal Muscular Atrophy (SMA): Updated Results From the SHINE Study', in NEUROLOGY, LIPPINCOTT WILLIAMS & WILKINS, Philadelphia, PA, Vol. 92, presented at 71st Annual Meeting of the American-Academy-of-Neurology (AAN), Philadelphia, PA, 04 May 2019 - 10 May 2019, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000475965906183&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2019
Kirschner J; Darras B; Farrar M; Mercuri E; Chiriboga C; Kuntz N; Shieh P; Tulinius M; Montes J; Reyna S; Gambino G; Foster R; Bhan I; Wong J; Farwell W, 2019, 'Interim report on the safety and efficacy of longer-term treatment with nusinersen in later-onset spinal muscular atrophy (SMA): results from the SHINE study', in NEUROMUSCULAR DISORDERS, PERGAMON-ELSEVIER SCIENCE LTD, Copenhagen, DENMARK, Vol. 29, pp. S184 - S184, presented at 24th International Annual Congress of the World-Muscle-Society (WMS), Copenhagen, DENMARK, 01 October 2019 - 05 October 2019, http://dx.doi.org/10.1016/j.nmd.2019.06.514
2019
Darras BT; Farrar MA; Mercuri E; Chiriboga CA; Kirschner J; Kuntz N; Shieh P; Tulinius M; Montes J; Gambino G; Foster R; Bhan I; Farwell W; Reyna SP, 2019, 'Interim Report on the Safety and Efficacy of Longer-term Treatment With Nusinersen in Later-onset Spinal Muscular Atrophy (SMA): Results From the SHINE Study', in NEUROLOGY, LIPPINCOTT WILLIAMS & WILKINS, Philadelphia, PA, Vol. 92, presented at 71st Annual Meeting of the American-Academy-of-Neurology (AAN), Philadelphia, PA, 04 May 2019 - 10 May 2019, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000475965900302&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2019
Seow C; Farrar M; Doumit M; Thambipillay G; Widger J; Jaffe A; Chuang SY, 2019, 'Compliance to Respiratory Care Guidelines for Children with Neuromuscular Disease at Sydney Children's Hospital', in AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, AMER THORACIC SOC, Dallas, TX, Vol. 199, presented at International Conference of the American-Thoracic-Society, Dallas, TX, 17 May 2019 - 22 May 2019, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000466771104303&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2019
Farrar MA; KAndula T; Murray J; Goldstein D; Krishnan A; PArk S, 2016, 'Subclinical peripheral neuropathy prior to chemotherapy in colorectal cancer patients – Myth or reality?', in Subclinical peripheral neuropathy prior to chemotherapy in colorectal cancer patients – Myth or reality?, ANZAN Biennial Clinical Neurophysiology Workshop, presented at ANZAN Biennial Clinical Neurophysiology Workshop, http://dx.doi.org/10.1016/j.clinph.2015.11.029
2016
Farrar MA; Chew K; Widger J, 2015, 'The Impact Of Nutrition On Respiratory Function In Duchenne Muscular Dystrophy', in The Impact Of Nutrition On Respiratory Function In Duchenne Muscular Dystrophy, Australian Thoracic Society ASM, presented at Australian Thoracic Society ASM
2015
Conference Papers
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Kirschner J; Darras BT; Farrar MA; Mercuri E; Chiriboga CA; Kuntz NL; Shieh PB; Tulinius M; Montes J; Reyna SP; Gambino G; Foster R; Bhan I; Wong J; Farwell W, 2019, 'Interim report on the safety and efficacy of longer-term treatment with nusinersen in later-onset spinal muscular atrophy (SMA): Results from the shine study', in JOURNAL OF THE NEUROLOGICAL SCIENCES, ELSEVIER, Emirates Neurol Soc, Dubai, U ARAB EMIRATES, presented at World Congress of Neurology (WCN), Emirates Neurol Soc, Dubai, U ARAB EMIRATES, 27 October 2019 - 31 October 2019, http://dx.doi.org/10.1016/j.jns.2019.10.1272
2019
Mandarakas M; Menezes M; Rose K; Shy R; Eichinger K; Foscan M; Estilow T; Kennedy R; Herbert K; Bray P; Refshauge K; Ryan M; Yiu E; Farrar M; Sampaio H; Moroni I; Pagliano E; Pareyson D; Yum S; Herrmann D; Acsadi G; Finkel R; Shy M; Burns J; Sanmaneechai O, 2018, 'Development and validation of the CMT infant scale', in JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM, WILEY, Baltimore, MD, pp. 322 - 323, presented at Annual Meeting of the Peripheral-Nerve-Society, Baltimore, MD, 21 July 2018 - 25 July 2018, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000452787700184&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2018
Oates E; Yau K; Jones K; Smith J; Cummings B; Farrar M; Cooper S; Lek M; Hoffman E; Straub V; Ferreiro A; Udd B; Beggs A; Bonnemann C; North K; MacArthur D; Granzier H; Muntoni F; Davis M; Laing N, 2017, 'Do titin developmental isoforms contribute to the pathogenesis of congenital titinopathy?', in NEUROMUSCULAR DISORDERS, PERGAMON-ELSEVIER SCIENCE LTD, Saint Malo, FRANCE, pp. S237 - S238, presented at 22nd International Annual Congress of the World-Muscle-Society (WMS), Saint Malo, FRANCE, 03 October 2017 - 07 October 2017, http://dx.doi.org/10.1016/j.nmd.2017.06.513
2017
Kandula T; Park S; Kiernan MC; Mizrahi D; Carey K; Cohn R; Krishnan A; Farrar M, 2016, 'Long term outcomes and risk factors for chemotherapy induced peripheral neuropathy in the paediatric population', in Long term outcomes and risk factors for chemotherapy induced peripheral neuropathy in the paediatric population, 14th International Child Neurology Congress, Amsterdam, presented at 14th International Child Neurology Congress, Amsterdam, 01 May 2016 - 05 May 2016
2016
Menezes MP; Farrar M; Burns J; Birman C; Gardener-Berry K; Kiernan M; Vucic S; Ouvrier R, 2015, 'RIBOFLAVIN TRANSPORTER MUTATIONS CAUSING BROWN-VIALETTO-VAN LAERE SYNDROME: UNIQUE CLINICAL AND AUDIOLOGICAL PROFILE, PATHOPHYSIOLOGY AND BENEFIT FROM RIBOFLAVIN', in JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM, WILEY-BLACKWELL, Quebec, CANADA, pp. 192 - 193, presented at Biennial Meeting of the Peripheral-Nerve-Society, Quebec, CANADA, 27 June 2015 - 02 July 2015, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000360214600274&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2015
Kandula T; Teoh HL; Andrews I; Bye A; Farrar MA, 2014, 'Enterovirus 71 associated lower motor neuron disease in infants and children', Amsterdam, The Netherlands, presented at 13th International Child Neurology Congress, Amsterdam, The Netherlands
2014
Lin CSY; Farrar M; Kiernan M, 2013, 'HOW DO NERVES RESPOND TO PRESSURE? HEREDITARY NEUROPATHY WITH LIABILITY TO PRESSURE PALSIES (HNPP)', in JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM, WILEY-BLACKWELL, Saint Malo, FRANCE, pp. 63 - 63, presented at Meeting of the Peripheral-Nerve-Society, Saint Malo, FRANCE, 29 June 2013 - 03 July 2013, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000320620200160&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2013
Menezes MP; Farrar MA; Burns J; Menon P; Webster R; Antony J; Kiernan MC; Vucic S, 2013, 'PERIPHERAL MOTOR CONTRIBUTIONS TO THE PATHOPHYSIOLOGY OF BVVL-RELATED MUTATIONS IN RIBOFLAVIN TRANSPORTER 3: PATHOPHYSIOLOGICAL INSIGHTS FROM NERVE EXCITABILITY TESTING', in JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM, WILEY-BLACKWELL, Saint Malo, FRANCE, pp. 71 - 72, presented at Meeting of the Peripheral-Nerve-Society, Saint Malo, FRANCE, 29 June 2013 - 03 July 2013, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000320620200182&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
2013
Farrar M; Lin CS-Y; Krishnan AV; Park SB; Andrews PI; Kiernan MC, 2010, 'Acute, reversible axonal energy failure during a stroke-like episode in MELAS', in Small D (ed.), 30th Annual Meeting of the Australian Neuroscience Society, Australian Neurosciences Society Annual Scientific Meeting 2010, Sydney, pp. 160 - 160, presented at Australian Neurosciences Society Annual Scientific Meeting 2010, Sydney, 31 January 2010 - 03 February 2010
2010
Farrar M; Vucic S; Johnston H; Kiernan MC, 2010, 'Mechanisms of Neurodegeneration in Spinal Muscular Atrophy', in Australian and New Zealand Association of Neurologists Annual Scientific Meeting 2010: Leaps and Bounds, Australian and New Zealand Association of Neurologists Annual Scientific Meeting 2010, Melbourne, presented at Australian and New Zealand Association of Neurologists Annual Scientific Meeting 2010, Melbourne, 17 May 2010 - 20 May 2010
2010
Sampaio H; Perera N; Farrar MA, 'Bone health in Duchenne muscular dystrophy: natural history, pathogenesis and treatment', Amsterdam, The Netherlands, presented at 13th International Child Neurology Congress, Amsterdam, The Netherlands
Kariyawasam D; Sampaio H; Mowat D; Farrar MA, 'Genetic carrier screening for duchenne muscular dystrophy: the outcome of over twenty years of genetic counselling on disease epidemiology in a single-centre cohort study in new south wales (NSW), australia', Sydney Australia, presented at Australian and New Zealand Association of Neurologists, Sydney Australia
Farrar M; Tomlinson S; Howells J; Lin S-Y; Park SB; Carey K; HOllingswoth G; Lawson J; Kiernan M; Berkovic S; Scheffer I, 'Axonal excitability properties in dravet’s syndrome reflect effect of loss of sodium channels', Sydney, presented at Australia and New Zealand Association of Neurologists, Sydney
Farrar M; Swoboda K; Schultz M; McMilan H; Parsons J; Alexander IE; Kernbauer ; Farrow M; Ogrinc F; Feltner D; McGill B; Spector S; LÍtalien J; Sproule D; Strauss K, 'AVXS-101 gene-replacement therapy (GRT) in presymptomatic spinal muscular atrophy (SMA): study update', presented at Australian and New Zealand Association of Neurologist
Farrar M; Castro D; Finkel RS; Tulinius M; Krosschell KJ; Saito K; Zhang Y; Bhan I; Farwell W; Reyna SP, 'Longer-term Assessment of the Safety and Efficacy of Nusinersen for the Treatment of Infantile-Onset Spinal Muscular Atrophy (SMA): An Interim Analysis of the SHINE Study', Dallas, United States, presented at Annual Cure SMA Conference, Dallas, United States
Conference Posters
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Farrar M; Carey K; Paguinto S; Chambers G; Kasparain N, 2017, 'Counting the uncounted costs of chronic Spinal Muscular Atrophy', Boston, United States, presented at American Academy of Neurology, Boston, United States
2017
Roscioli T; Teoh HL; Zhu Y; Sampaio H; Mowat D; Buckley M; Farrar MA, 2016, 'Next Generation Sequencing in Spinal muscular atrophy syndromes', Kyoto, Japan, presented at 13th International Congress of Human Genetics, Kyoto, Japan
2016
Chew K; Farrar M; Widger J, 2015, 'THE IMPACT OF NUTRITION ON RESPIRATORY FUNCTION IN DUCHENNE MUSCULAR DYSTROPHY', Queensland, AUSTRALIA, Vol. 20, pp. 91 - 91, presented at Thoracic Society Australia New Zealand Australian New Zealand Society Respiratory Science Annual Scientific Meeting 2015, Queensland, AUSTRALIA, 27 March 2015 - 01 April 2015, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000351464400235&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
2015
Farrar M; Lin CS-Y; Krishnan AV; Park SB; Andrews PI; Kiernan MC, 2009, 'Acute, reversible axonal energy failure during a stroke-like episode in MELAS', Southport, Queensland, presented at Neurophysiology Workshop of the Australian and New Zealand Association of Neurologists, Southport, Queensland, 04 October 2009 - 07 October 2009
2009
McNeill E; Finkel R; Darras B; Kirschner J; Farrar MA; Ryan MM; Zhong Z; Gheuens S; Farwell W, 'Nusinersen Improves Motor Function in Infants with and without Permanent Ventilation: Results from the ENDEAR Study in Infantile-Onset Spinal Muscular Atrophy', Boston, United States, presented at 69th Annual Meeting of the American Academy of Neurology, Boston, United States
Sampaio H; Farrar MA; AlSafar A, 'Recurrent rhabdomyolysis and subtle proximal weakness in two female siblings diagnosed with alpha sarcoglycanopathy and a review of the literature', presented at World Muscle Society
Sampaio H; Al Safar A; Farrar MA, '267Local experience of hyperCKaemia in a multidisciplinary neuromuscular clinic', presented at World Muscle Society
Farrar M; Ho G; Carey K; Cardamone M, 'Myotonic Dystrophy Type 1: Clinical manifestations in children and adolescents', Taiwan, presented at 15th Asian and Oceanic Myology Congress and Taiwanese Child Neurology Society Annual Scientific Meeting, Taiwan
Conference Presentations
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Farrar M, 2017, 'Australian and New Zealand Association of Neurologists Leonard Cox Award: Findings in Nerve Neverland: a neuromuscular adventure', presented at Australia and New Zeealand Association of Neurologists Annual Scientific Meeting, Australia
2017
Farrar M, 2017, 'Progress and challenges in Spinal Muscular Atrophy, Invited plenary presentation.', presented at Australia and New Zealand Child Neurology Society annual scientific meeting, Australia
2017
Farrar M, 'Resource allocation in rare neurological disease: should the few benefit rather than the many? Invited presentation at Australian and New Zealand Association of Neurologists Annual Scientific Meeting', presented at Australian and New Zealand Association of Neurologists Annual Scientific Meeting, Sydney, Australia
Farrar M, 'Nerve excitability studies in paediatrics', presented at 9th International Paediatric EMG conference, Cambridge, United Kingdom
Farrar M, 'Treating spinal muscular atrophy, invited plenary presentation 42nd Human Genetics Society of Australia Annual Scientific Meeting.', presented at 42nd Human Genetics Society of Australia Annual Scientific Meeting., Sydney, Australia
Farrar M, 'Australasian experiences of diagnosis, standard of care and clinical trials of spinal muscular atrophy. Invited plenary presentation', presented at 15th Asian and Oceanic Myology Congress and Taiwanese Child Nezurology Society Annual Scientific meeting, Taiwan
Book Chapters
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Farrar M; Kiernan MC, 2011, 'Spinal Muscular Atrophy', in Encyclopedia of Life Sciences (eLS), edn. 3rd, John Wiley & Sons, Ltd., Chichester, pp. 1 - 7, http://dx.doi.org/10.1002/9780470015902.a0006011.pub2
2011
  • Michelle Beets Memorial Silver Award (2018) NSW Health and Humpty Dumpty Foundation for improving health outcomes for children
  • Leonard Cox Award, Australian and New Zealand Association of Neurologists (2017) for contributions to Australian neuroscience

https://med.unsw.edu.au/news/michelle-farrar-recognised-leonard-cox-award

  • School of Women’s and Children’s Health, UNSW Sydney Best publication award (2017)
  • Dean’s Rising Star Award, UNSW Medicine, UNSW Sydney (2016)
  • Asian Oceanian Myology Centre Fellowship award for outstanding presentation (2016)
  • James Lance Young Investigator Award, Australia and New Zealand Association of Neurologists (2010)
Ravenscroft G; Farrar MA; Ong R; Liang N, 2017, What prospective parents need to know about gene tests such as ‘prepair’, https://theconversation.com/what-prospective-parents-need-to-know-about-gene-tests-such-as-prepair-87083
2017