Mark Larsen

Senior Research Fellow

Dr Mark Larsen is a Research Fellow at the Black Dog Institute. His research examines how technology can be used to deliver effective mental health interventions to reduce the risk of suicide, particularly among those that have made a previous attempt. His research also explores the use of passive smartphone data collection to detect changes in mental health. He was awarded a 2015 Society for Mental Health Research Fellowship for his project on follow-up supportive text messages following a visit to the emergency department after a suicide attempt.

Dr Larsen completed his DPhil in Biomedical Engineering at the University of Oxford, and received a Masters in Electronic and Electrical Engineering from the University of Strathclyde. His doctoral thesis developed and evaluated mobile phone apps for self-management in type 2 diabetes, and symptom management during chemotherapy. He completed post-doctoral training at the University of Oxford and the Department of Primary Care and Public Health at Imperial College London. He is a member of the Society for Mental Health Research, the IET Healthcare Technologies Network, the IEEE Engineering in Medicine and Biology Society, and the Editorial Board of JMIR Mental Health.

publications

Journal articles
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Werner-Seidler A; Huckvale K; Larsen ME; Calear AL; Maston K; Johnston L; Torok M; O'Dea B; Batterham PJ; Schweizer S; Skinner SR; Steinbeck K; Ratcliffe J; Oei JL; Patton G; Wong I; Beames J; Wong QJJ; Lingam R; Boydell K; Salmon AM; Cockayne N; Mackinnon A; Christensen H, 2020, 'A trial protocol for the effectiveness of digital interventions for preventing depression in adolescents: The Future Proofing Study', Trials, vol. 21, pp. 2, http://dx.doi.org/10.1186/s13063-019-3901-7
2020
Torok M; Han J; Baker S; Werner-Seidler A; Wong I; Larsen ME; Christensen H, 2020, 'Suicide prevention using self-guided digital interventions: a systematic review and meta-analysis of randomised controlled trials', The Lancet Digital Health, vol. 2, pp. e25 - e36, http://dx.doi.org/10.1016/S2589-7500(19)30199-2
2020
Larsen ME; Torok M; Onie S, 2020, 'Understanding the effects of a suicide prevention strategy at a jumping site', EClinicalMedicine, vol. 19, pp. 100278 - 100278, http://dx.doi.org/10.1016/j.eclinm.2020.100278
2020
Huckvale K; Torous J; Larsen ME, 2019, 'Assessment of the Data Sharing and Privacy Practices of Smartphone Apps for Depression and Smoking Cessation', JAMA network open, vol. 2, pp. e192542, http://dx.doi.org/10.1001/jamanetworkopen.2019.2542
2019
Lemey C; Larsen ME; Devylder J; Courtet P; Billot R; Lenca P; Walter M; Baca-García E; Berrouiguet S, 2019, 'Clinicians' concerns about mobile ecological momentary assessment tools designed for emerging psychiatric problems: Prospective acceptability assessment of the memind app', Journal of Medical Internet Research, vol. 21, pp. e10111, http://dx.doi.org/10.2196/10111
2019
Batterham PJ; Calear AL; O’Dea B; Larsen ME; J Kavanagh D; Titov N; March S; Hickie I; Teesson M; Dear BF; Reynolds J; Lowinger J; Thornton L; Gorman P, 2019, 'Stakeholder perspectives on evidence for digital mental health interventions: Implications for accreditation systems', Digital Health, vol. 5, http://dx.doi.org/10.1177/2055207619878069
2019
Berrouiguet S; Larsen M; Walter M; Ropars J, 2019, 'Comment on “Associations between sleep duration and suicidality in adolescents: A systematic review and dose-response meta-analysis”', Sleep Medicine Reviews, vol. 47, pp. 125 - 126, http://dx.doi.org/10.1016/j.smrv.2019.07.002
2019
Torok M; Shand F; Phillips M; Meteoro N; Martin D; Larsen M, 2019, 'Data-informed targets for suicide prevention: a small-area analysis of high-risk suicide regions in Australia', Social Psychiatry and Psychiatric Epidemiology, vol. 54, pp. 1209 - 1218, http://dx.doi.org/10.1007/s00127-019-01716-8
2019
Larsen ME; Huckvale K; Nicholas J; Torous J; Birrell L; Li E; Reda B, 2019, 'Using science to sell apps: Evaluation of mental health app store quality claims.', NPJ Digit Med, vol. 2, pp. 18, http://dx.doi.org/10.1038/s41746-019-0093-1
2019
Berrouiguet S; Billot R; Larsen ME; Lopez-Castroman J; Jaussent I; Walter M; Lenca P; Baca-García E; Courtet P, 2019, 'An approach for data mining of electronic health record data for suicide risk management: Database analysis for clinical decision support', Journal of Medical Internet Research, vol. 21, pp. e9766, http://dx.doi.org/10.2196/mental.9766
2019
Nguyen T; Larsen M; O'Dea B; Nguyen H; Nguyen DT; Yearwood J; Phung D; Venkatesh S; Christensen HM, 2018, 'Using spatiotemporal distribution of geocoded Twitter data to predict US county-level health indices', Future Generation Computer Systems, http://dx.doi.org/10.1016/j.future.2018.01.014
2018
Torous J; Nicholas J; Larsen ME; Firth J; Christensen H, 2018, 'Clinical review of user engagement with mental health smartphone apps: Evidence, theory and improvements', Evidence-Based Mental Health, vol. 21, pp. 116 - 119, http://dx.doi.org/10.1136/eb-2018-102891
2018
Berrouiguet S; Courtet P; Larsen ME; Walter M; Vaiva G, 2018, 'Suicide prevention: Towards integrative, innovative and individualized brief contact interventions', European Psychiatry, vol. 47, pp. 25 - 26, http://dx.doi.org/10.1016/j.eurpsy.2017.09.006
2018
Torous J; Firth J; Huckvale K; Larsen ME; Cosco TD; Carney R; Chan S; Pratap A; Yellowlees P; Wykes T; Keshavan M; Christensen H, 2018, 'The Emerging Imperative for a Consensus Approach Toward the Rating and Clinical Recommendation of Mental Health Apps', The Journal of nervous and mental disease, vol. 206, pp. 662 - 666, http://dx.doi.org/10.1097/NMD.0000000000000864
2018
Berrouiguet S; Perez-Rodriguez MM; Larsen M; Baca-García E; Courtet P; Oquendo M, 2018, 'From eHealth to iHealth: Transition to participatory and personalized medicine in mental health', Journal of Medical Internet Research, vol. 20, http://dx.doi.org/10.2196/jmir.7412
2018
O'Dea B; Achilles MR; Larsen ME; Batterham PJ; Calear AL; Christensen H, 2018, 'The rate of reply and nature of responses to suicide-related posts on Twitter', Internet Interventions, vol. 13, pp. 105 - 107, http://dx.doi.org/10.1016/j.invent.2018.07.004
2018
Larsen M; Vaughan P; Bennett J; Boydell K, 2018, 'The ‘BIG Anxiety Project’: Using the arts to visually explore public experiences and attitudes to anxiety', Journal of Applied Arts & Health, vol. 9, pp. 85 - 97, http://dx.doi.org/10.1386/jaah.9.1.85_1
2018
Clus D; Larsen ME; Lemey C; Berrouiguet S, 2018, 'The use of virtual reality in patients with eating disorders: Systematic review', Journal of Medical Internet Research, vol. 20, http://dx.doi.org/10.2196/jmir.7898
2018
Torous J; Larsen ME; Depp C; Cosco TD; Barnett I; Nock MK; Firth J, 2018, 'Smartphones, Sensors, and Machine Learning to Advance Real-Time Prediction and Interventions for Suicide Prevention: a Review of Current Progress and Next Steps', Current Psychiatry Reports, vol. 20, http://dx.doi.org/10.1007/s11920-018-0914-y
2018
Berrouiguet S; Larsen ME; Mesmeur C; Gravey M; Billot R; Walter M; Lemey C; Lenca P, 2018, 'Toward mhealth brief contact interventions in suicide prevention: Case series from the suicide intervention assisted by messages (SIAM) randomized controlled trial', JMIR mHealth and uHealth, vol. 6, http://dx.doi.org/10.2196/mhealth.7780
2018
Vaiva G; Berrouiguet S; Walter M; Courtet P; Ducrocq F; Jardon V; Larsen ME; Cailhol L; Godesense C; Couturier C; Mathur A; Lagree V; Pichene C; Travers D; Lemogne C; Henry JM; Jover F; Chastang F; Prudhomme O; Lestavel P; Gignac CT; Duhem S; Demarty AL; Mesmeur C; Bellivier F; Labreuche J; Duhamel A; Goldstein P, 2018, 'Combining postcards, crisis cards, and telephone contact into a decision-making algorithm to reduce suicide reattempt: A randomized clinical trial of a personalized brief contact intervention', Journal of Clinical Psychiatry, vol. 79, http://dx.doi.org/10.4088/JCP.17m11631
2018
Nicholas J; Huckvale K; Larsen ME; Basu A; Batterham PJ; Shaw F; Sendi S, 2017, 'Issues for eHealth in psychiatry: Results of an expert survey', Journal of Medical Internet Research, vol. 19, http://dx.doi.org/10.2196/jmir.6957
2017
Nguyen T; Larsen ME; O'Dea B; Nguyen DT; Yearwood J; Phung D; Venkatesh S; Christensen H, 2017, 'Kernel-based features for predicting population health indices from geocoded social media data', Decision Support Systems, vol. 102, pp. 22 - 31, http://dx.doi.org/10.1016/j.dss.2017.06.010
2017
Larsen ME; Shand F; Morley K; Batterham PJ; Petrie K; Reda B; Berrouiguet S; Haber PS; Carter G; Christensen H, 2017, 'A Mobile Text Message Intervention to Reduce Repeat Suicidal Episodes: Design and Development of Reconnecting After a Suicide Attempt (RAFT).', JMIR Ment Health, vol. 4, pp. e56, http://dx.doi.org/10.2196/mental.7500
2017
Boonstra TW; Larsen ME; Townsend S; Christensen H, 2017, 'Validation of a smartphone app to map social networks of proximity', PLoS ONE, vol. 12, http://dx.doi.org/10.1371/journal.pone.0189877
2017
Nguyen T; Larsen ME; O'Dea B; Phung D; Venkatesh S; Christensen H, 2017, 'Estimation of the prevalence of adverse drug reactions from social media', International Journal of Medical Informatics, vol. 102, pp. 130 - 137, http://dx.doi.org/10.1016/j.ijmedinf.2017.03.013
2017
O'Dea B; Larsen ME; Batterham PJ; Calear AL; Christensen H, 2017, 'A Linguistic analysis of suicide-related Twitter posts', Crisis, vol. 38, pp. 319 - 329, http://dx.doi.org/10.1027/0227-5910/a000443
2017
Larsen ME; Nicholas J; Christensen H, 2016, 'Quantifying App Store Dynamics: Longitudinal Tracking of Mental Health Apps', JMIR MHEALTH AND UHEALTH, vol. 4, http://dx.doi.org/10.2196/mhealth.6020
2016
Larsen ME; Nicholas J; Christensen H, 2016, 'A systematic assessment of smartphone tools for suicide prevention', PLoS ONE, vol. 11, pp. e0152285, http://dx.doi.org/10.1371/journal.pone.0152285
2016
Larsen ME; Curry L; Mastellos N; Robb C; Car J; Middleton LT, 2015, 'Development of the CHARIOT research register for the prevention of Alzheimer's dementia and other late onset neurodegenerative diseases', PLoS ONE, vol. 10, http://dx.doi.org/10.1371/journal.pone.0141806
2015
Townsend S; Larsen ME; Boonstra TW; Christensen H, 2015, 'Using Bluetooth Low Energy in smartphones to map social networks', arXiv preprint arXiv:1508.03938
2015
Larsen M; Boonstra T; Batterham P; O'Dea B; Paris C; Christensen H, 2015, 'We Feel: Mapping emotion on Twitter', IEEE Journal of Biomedical and Health Informatics, vol. 19, pp. 1246 - 1252, http://dx.doi.org/10.1109/JBHI.2015.2403839
2015
Nicholas J; Larsen ME; Proudfoot J; Christensen H, 2015, 'Mobile apps for bipolar disorder: A systematic review of features and content quality', Journal of Medical Internet Research, vol. 17, http://dx.doi.org/10.2196/jmir.4581
2015
Mastellos N; Andreasson A; Huckvale K; Larsen M; Curcin V; Car J; Agreus L; Delaney B, 2015, 'A cluster randomised controlled trial evaluating the effectiveness of eHealth-supported patient recruitment in primary care research: The TRANSFoRm study protocol', Implementation Science, vol. 10, http://dx.doi.org/10.1186/s13012-015-0207-3
2015
Nguyen T; O’Dea B; Larsen M; Phung D; Venkatesh S; Christensen H, 2015, 'Using linguistic and topic analysis to classify sub-groups of online depression communities', Multimedia Tools and Applications, vol. 76, pp. 10653 - 10676, http://dx.doi.org/10.1007/s11042-015-3128-x
2015
Boonstra TW; Larsen ME; Christensen H, 2015, 'Mapping dynamic social networks in real life using participants' own smartphones', Heliyon, vol. 1, http://dx.doi.org/10.1016/j.heliyon.2015.e00037
2015
Weaver A; Love SB; Larsen M; Shanyinde M; Waters R; Grainger L; Shearwood V; Brooks C; Gibson O; Young AM; Tarassenko L, 2014, 'A pilot study: dose adaptation of capecitabine using mobile phone toxicity monitoring — supporting patients in their homes', Supportive Care in Cancer, vol. 22, pp. 2677 - 2685, http://dx.doi.org/10.1007/s00520-014-2224-1
2014
Nagrebetsky A; Larsen M; Craven A; Turner J; McRobert N; Murray E; Gibson O; Neil A; Tarassenko L; Farmer A, 2013, 'Stepwise self-titration of oral glucose-lowering medication using a mobile telephone-based telehealth platform in type 2 diabetes: A feasibility trial in primary care', Journal of Diabetes Science and Technology, vol. 7, pp. 123 - 134, http://dx.doi.org/10.1177/193229681300700115
2013
Larsen ME; Turner J; Farmer A; Neil A; Tarassenko L, 2010, 'Telemedicine-supported insulin optimisation in primary care', Journal of Telemedicine and Telecare, vol. 16, pp. 433 - 440, http://dx.doi.org/10.1258/jtt.2010.100103
2010
Turner J; Larsen M; Tarassenko L; Neil A; Farmer A, 2009, 'Implementation of telehealth support for patients with type 2 diabetes using insulin treatment: An exploratory study', Informatics in Primary Care, vol. 17, pp. 47 - 53
2009
Weaver A; Young AM; Rowntree J; Townsend N; Pearson S; Smith J; Gibson O; Cobern W; Larsen M; Tarassenko L, 2007, 'Application of mobile phone technology for managing chemotherapy-associated side-effects', Annals of Oncology, vol. 18, pp. 1887 - 1892, http://dx.doi.org/10.1093/annonc/mdm354
2007
Conference Papers
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Larsen ME; Torok M; Huckvale K; Reda B; Berrouiguet S; Christensen H, 2019, 'Geospatial suicide clusters and emergency responses: An analysis of text messages to a crisis service', in Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, IEEE, pp. 6109 - 6112, presented at 2019 41st Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC), 23 July 2019 - 27 July 2019, http://dx.doi.org/10.1109/EMBC.2019.8856909
2019
Billot R; Berrouiguet S; Larsen M; Walter M; Castroman JL; Baca-García E; Courtet P; Lenca P, 2018, 'Apport de la fouille de données pour la prévention du risque suicidaire', in Apport de la fouille de données pour la prévention du risque suicidaire, Conférence Internationale sur l'Extraction et la Gestion des Connaissances, Revue des Nouvelles Technologies de l'Information, Paris, France, pp. 143 - 154, presented at Conférence Internationale sur l'Extraction et la Gestion des Connaissances, Revue des Nouvelles Technologies de l'Information, Paris, France, 22 January 2018 - 26 January 2018, https://hal.archives-ouvertes.fr/hal-01694714/
2018
Nguyen H; Nguyen V; Nguyen T; Larsen ME; O’Dea B; Nguyen DT; Le T; Phung D; Venkatesh S; Christensen H, 2018, 'Jointly predicting affective and mental health scores using deep neural networks of visual cues on the web', in hacid H; Cellary W; Wang H; Paik H-Y; Zhou R (eds.), Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), Springer, Cham, Dubai, United Arab Emirates, pp. 100 - 110, presented at International Conference on Web Information Systems Engineering : WISE 2018, Dubai, United Arab Emirates, 12 November 2018 - 15 November 2018, http://dx.doi.org/10.1007/978-3-030-02925-8_7
2018
Watkins NG; Lovell NH; Larsen ME, 2018, 'SMCT - An Innovative Tool for Mental Health Analysis of Twitter Data', in Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, pp. 4114 - 4117, http://dx.doi.org/10.1109/EMBC.2018.8513257
2018
Boonstra T; Werner-Seidler A; O'Dea B; Larsen M; Christensen HM, 2017, 'Smartphone app to investigate the relationship between social connectivity and mental health', in Engineering in Medicine and Biology Society (EMBC), 2017 39th Annual International Conference of the IEEE, IEEE, Seogwipo, South Korea, pp. 287 - 290, presented at 2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), Seogwipo, South Korea, 11 July 2017 - 15 July 2017, http://dx.doi.org/10.1109/EMBC.2017.8036818
2017
Nguyen T; Nguyen DT; Larsen M; O'Dea B; Yearwood J; Phung D; Venkatesh S; Christensen H, 2017, 'Prediction of Population Health Indices from Social Media using Kernel-based Textual and Temporal Features', in Proceedings of the 26th International Conference on World Wide Web Companion, International World Wide Web Conferences Steering Committee, Perth, Australia, pp. 99 - 107, presented at International World Wide Web Conference, Perth, Australia, 03 April 2017 - 07 April 2017, http://dx.doi.org/10.1145/3041021.3054136
2017
Larsen ME; Cummins N; Boonstra TW; O'Dea B; Tighe J; Nicholas J; Shand F; Epps J; Christensen H, 2015, 'The use of technology in Suicide Prevention', in Engineering in Medicine and Biology Society (EMBC), pp. 7316 - 7319, http://dx.doi.org/10.1109/EMBC.2015.7320081
2015
Nguyen T; O'Dea B; Larsen ME; Phung D; Venkatesh S; Christensen HM, 2015, 'Differentiating Sub-groups of Online Depression-Related Communities Using Textual Cues', in Lecture Notes in Computer Science, Springer Verlag, Miami, FL, USA, pp. 216 - 224, presented at Web Information Systems Engineering – WISE 2015, Miami, FL, USA, 01 November 2015 - 03 November 2015, http://dx.doi.org/10.1007/978-3-319-26187-4_17
2015
Larsen ME; Farmer A; Weaver A; Young A; Tarassenko L, 2011, 'Mobile health for drug dose optimisation', in Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, pp. 1540 - 1543, http://dx.doi.org/10.1109/IEMBS.2011.6090449
2011
Larsen ME; Rowntree J; Young AM; Pearson S; Smith J; Gibson OJ; Weaver A; Tarassenko L, 2008, 'Chemotherapy side-effect management using mobile phones.', in Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference, pp. 5152 - 5155
2008
Conference Abstracts
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Chia J; Shand F; Morley K; Haber P; Larsen M, 2018, 'Reconnecting AFTer self-harm (RAFT) - A technology based brief contact intervention', in INTERNATIONAL JOURNAL OF MENTAL HEALTH NURSING, WILEY, Vol. 27, pp. 8 - 8
2018
O'Dea B; Larsen M; Batterham P; Calear A; Christensen H, 2016, 'Talking suicide on Twitter: Linguistic style and language processes of suicide-related posts', in European Psychiatry, Elsevier, Madrid, Spain, Vol. 33, pp. S274 - S274, presented at 24th European Congress of Psychiatry, Madrid, Spain, 12 March 2016 - 15 March 2016, http://dx.doi.org/10.1016/j.eurpsy.2016.01.727
2016
Nicholas J; Larsen ME; Christensen H; Proudfoot J, 2015, 'Systematic assessment of mobile apps for bipolar disorder: features and content', in BIPOLAR DISORDERS, WILEY-BLACKWELL, Vol. 17, pp. 129 - 129, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000355338100366&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2015
Larsen ME; Gibson OJ; Nagrebetsky A; Farmer AJ; Tarassenko L, 2012, 'Oral Medication Adjustment with Telehealth Support (MATS) for type-2 diabetes', in 2012 Diabetes Technology Meeting, Diabetes Technology Society, pp. A76 - A76, Diabetes Technology Society
2012
Turner J; Larsen M; Gibson O; Simpson H; Tarassenko L; Neil HAW; Farmer AJ, 2009, 'A Telehealth System to Optimise Insulin Titration in Primary Care', in 2009 Diabetes UK Annual Professional Conference, Diabetes UK, Diabetes UK
2009
Garland ZM; Powell T; Larsen E; O Brian N; Jarad NA, 2007, 'Remote daily real time monitoring of symptoms in patients with chronic obstructive pulmonary disease (COPD): Mobile technology and exacerbations (MOTEX) study', in THORAX-LONDON-, BMJ PUBLISHING GROUP, Vol. 62, pp. P234 - P234
2007
Patents
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Tarassenko L; Gibson OJ; Larsen ME, 2008, System for monitoring chemotherapy-associated adverse drug reactions, Patent No.
2008