Maria Kavallaris

co-Founding Director, Australian Centre for NanoMedicine, UNSW; Head, Translational Cancer NanoMedicine Theme, Children's Cancer Institute
Conjoint Professor

Professor Maria Kavallaris AM is Founding Director of the Australian Centre for NanoMedicine at the University of New South Wales, Head of the Translational Cancer Nanomedicine Theme at the Children’s Cancer Institute and a National Health and Medical Research Council (NHMRC) Principal Research Fellow. Maria is recognised for her innovation in driving multidisciplinary research in cancer nanomedicine. An outstanding scientific leader, she is internationally recognised for her research in cancer biology and therapeutics. Her research has identified clinically important mechanisms of resistance to cancer therapies, with her discoveries leading to patents, industry and clinical linkages for the development of cancer therapeutics and devices. Maria’s pioneering research has shown effective nanoparticle-based delivery of gene silencing material and chemotherapy, can reduce tumour growth in aggressive cancers. 

Maria is Chair of the Australian Institute for Policy and Science, and a Life Member and past-President of the Australian Society for Medical Research. The impact of her research has been recognised many times, including via receipt of the Australian Museum Eureka Prize, as well as being named by the NHMRC as an Australian ‘high achiever’ in health and medical research. Recognition of her significant contributions to innovation is reflected in her being named in 2015 amongst the AFR/Westpac 100 Women of Influence (Innovation category), as well as the inaugural Knowledge Nation 100 – the ‘rock stars’ of Australia's innovation-driven new economy, and she received the 2017 Premiers Science and Engineering Award for Leadership in Innovation in NSW. In 2019, she was awarded the Lemberg Medal, a prestigious award bestowed by ASBMB; and has won both the 2019 UTS Chancellor’s Excellence Award and the 2019 UTS Alumni Excellence Award for Science. She is an elected Fellow of both the Australian Academy of Health and Medical Sciences and the Royal Society of New South Wales.  Maria was named the 2020 NSW Premier's Woman of the Year.   

A recognised medical research leader, she has been appointed on government funding panels including NHMRC Research Committee and the Medical Research Future Fund Stem Cell Therapies Advisory Committee, where she contributes to high level policy. In 2019, Maria was appointed a Member (AM) of the Order of Australia for her significant service to medicine, and to medical research, in the field of childhood and adult cancers.

 

Journal articles
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Po’uha ST; Le Grand M; Brandl MB; Gifford AJ; Goodall GJ; Khew-Goodall Y; Kavallaris M, 2020, 'Stathmin levels alter PTPN14 expression and impact neuroblastoma cell migration', British Journal of Cancer, vol. 122, pp. 434 - 444, http://dx.doi.org/10.1038/s41416-019-0669-1
2020
Tjandra KC; McCarthy N; Yang L; Laos AJ; Sharbeen G; Phillips PA; Forgham H; Sagnella SM; Whan RM; Kavallaris M; Thordarson P; McCarroll JA, 2019, 'Identification of Novel Medulloblastoma Cell-Targeting Peptides for Use in Selective Chemotherapy Drug Delivery', Journal of Medicinal Chemistry, http://dx.doi.org/10.1021/acs.jmedchem.9b00851
2019
Somers K; Wen VW; Middlemiss SMC; Osborne B; Forgham H; Jung MS; Karsa M; Clifton M; Bongers A; Gao J; Mayoh C; Raoufi-Rad N; Kusnadi EP; Hannan KM; Scott DA; Kwek A; Liu B; Flemming C; Chudakova DA; Pandher R; Failes TW; Lim J; Angeli A; Osterman AL; Imamura T; Kees UR; Supuran CT; Pearson RB; Hannan RD; Davis TP; McCarroll J; Kavallaris M; Turner N; Gudkov AV; Haber M; Norris MD; Henderson MJ, 2019, 'A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction', Oncogene, vol. 38, pp. 3824 - 3842, http://dx.doi.org/10.1038/s41388-018-0666-5
2019
Moles E; Kavallaris M, 2019, 'A potent targeted cancer nanotherapeutic', Nature Biomedical Engineering, vol. 3, pp. 248 - 250, http://dx.doi.org/10.1038/s41551-019-0390-7
2019
Cirillo G; Peitzsch C; Vittorio O; Curcio M; Farfalla A; Voli F; Dubrovska A; Iemma F; Kavallaris M; Hampel S, 2019, 'When polymers meet carbon nanostructures: expanding horizons in cancer therapy', Future medicinal chemistry, vol. 11, pp. 2205 - 2231, http://dx.doi.org/10.4155/fmc-2018-0540
2019
Bayat N; McOrist N; Ariotti N; Lai M; Sia KCS; Li Y; Grace JL; Quinn JF; Whittaker MR; Kavallaris M; Davis TP; Lock RB, 2019, 'Thiol-reactive star polymers functionalized with short ethoxy-containing moieties exhibit enhanced uptake in acute lymphoblastic leukemia cells', International Journal of Nanomedicine, vol. 14, pp. 9795 - 9808, http://dx.doi.org/10.2147/IJN.S220326
2019
Moles E; Kavallaris M; Fernàndez-Busquets X, 2019, 'Modeling the distribution of diprotic basic drugs in liposomal systems: Perspectives on malaria nanotherapy', Frontiers in Pharmacology, vol. 10, http://dx.doi.org/10.3389/fphar.2019.01064
2019
Xie W; Guo Z; Cao Z; Gao Q; Wang D; Boyer C; Kavallaris M; Sun X; Wang X; Zhao L; Gu Z, 2019, 'Manganese-Based Magnetic Layered Double Hydroxide Nanoparticle: A pH-Sensitive and Concurrently Enhanced T1/ T2-Weighted Dual-Mode Magnetic Resonance Imaging Contrast Agent', ACS Biomaterials Science and Engineering, vol. 5, pp. 2555 - 2562, http://dx.doi.org/10.1021/acsbiomaterials.8b01618
2019
Parker SG; Yang Y; Ciampi S; Gupta B; Kimpton K; Mansfeld FM; Kavallaris M; Gaus K; Justin Gooding J, 2018, 'A photoelectrochemical platform for the capture and release of rare single cells', Nature Communications, vol. 9, http://dx.doi.org/10.1038/s41467-018-04701-y
2018
Faria M; Björnmalm M; Thurecht KJ; Kent SJ; Parton RG; Kavallaris M; Johnston APR; Gooding JJ; Corrie SR; Boyd BJ; Thordarson P; Whittaker AK; Stevens MM; Prestidge CA; Porter CJH; Parak WJ; Davis TP; Crampin EJ; Caruso F, 2018, 'Minimum information reporting in bio–nano experimental literature', Nature Nanotechnology, vol. 13, pp. 777 - 785, http://dx.doi.org/10.1038/s41565-018-0246-4
2018
Oliver S; Yee E; Kavallaris M; Vittorio O; Boyer C, 2018, 'Water Soluble Antioxidant Dextran–Quercetin Conjugate with Potential Anticancer Properties', Macromolecular Bioscience, vol. 18, http://dx.doi.org/10.1002/mabi.201700239
2018
Chang D; Lim M; Goos JACM; Qiao R; Ng YY; Mansfeld FM; Jackson M; Davis TP; Kavallaris M, 2018, 'Biologically targeted magnetic hyperthermia: Potential and limitations', Frontiers in Pharmacology, vol. 9, http://dx.doi.org/10.3389/fphar.2018.00831
2018
Sagnella SM; Trieu J; Brahmbhatt H; MacDiarmid JA; MacMillan A; Whan RM; Fife CM; McCarroll JA; Gifford AJ; Ziegler DS; Kavallaris M, 2018, 'Targeted doxorubicin-loaded bacterially derived nano-cells for the treatment of neuroblastoma', Molecular Cancer Therapeutics, vol. 17, pp. 1012 - 1023, http://dx.doi.org/10.1158/1535-7163.MCT-17-0738
2018
Parker AL; Teo WS; Pandzic E; Vicente JJ; McCarroll JA; Wordeman L; Kavallaris M, 2018, 'β-Tubulin carboxy-terminal tails exhibit isotype-specific effects on microtubule dynamics in human gene-edited cells', Life Science Alliance, vol. 1, http://dx.doi.org/10.26508/lsa.201800059
2018
Parmar A; Pascali G; Voli F; Lerra L; Yee E; Ahmed-Cox A; Kimpton K; Cirillo G; Arthur A; Zahra D; Rahardjo G; Liu GJ; Lengkeek N; Saletta F; Charil A; Kavallaris M; Vittorio O, 2018, 'In vivo [64Cu]CuCl2 PET imaging reveals activity of dextran-Catechin on tumor copper homeostasis', Theranostics, vol. 8, pp. 5645 - 5659, http://dx.doi.org/10.7150/thno.29840
2018
Levrier C; Rockstroh A; Gabrielli B; Kavallaris M; Lehman M; Davis RA; Sadowski MC; Nelson CC, 2018, 'Discovery of thalicthuberine as a novel antimitotic agent from nature that disrupts microtubule dynamics and induces apoptosis in prostate cancer cells', Cell Cycle, vol. 17, pp. 652 - 668, http://dx.doi.org/10.1080/15384101.2017.1356512
2018
Tavallaie R; McCarroll J; Le Grand M; Ariotti N; Schuhmann W; Bakker E; Tilley RD; Hibbert DB; Kavallaris M; Gooding JJ, 2018, 'Nucleic acid hybridization on an electrically reconfigurable network of gold-coated magnetic nanoparticles enables microRNA detection in blood', Nature Nanotechnology, vol. 13, pp. 1066 - 1071, http://dx.doi.org/10.1038/s41565-018-0232-x
2018
Parker AL; Teo WS; McCarroll JA; Kavallaris M, 2017, 'An emerging role for tubulin isotypes in modulating cancer biology and chemotherapy resistance', International Journal of Molecular Sciences, vol. 18, http://dx.doi.org/10.3390/ijms18071434
2017
Wojciechowski JP; Martin AD; Mason AF; Fife CM; Sagnella SM; Kavallaris M; Thordarson P, 2017, 'Choice of Capping Group in Tripeptide Hydrogels Influences Viability in the Three-Dimensional Cell Culture of Tumor Spheroids', ChemPlusChem, vol. 82, pp. 383 - 389, http://dx.doi.org/10.1002/cplu.201600464
2017
Fife CM; Sagnella SM; Teo WS; Po'uha ST; Byrne FL; Yeap YY; Ng DC; Davis TP; McCarroll JA; Kavallaris M, 2017, 'Stathmin mediates neuroblastoma metastasis in a tubulin-independent manner via RhoA/ROCK signaling and enhanced transendothelial migration.', Oncogene, vol. 36, pp. 501 - 511, http://dx.doi.org/10.1038/onc.2016.220
2017
Oliver S; Jofri A; Thomas DS; Vittorio O; Kavallaris M; Boyer C, 2017, 'Tuneable catechin functionalisation of carbohydrate polymers', Carbohydrate Polymers, vol. 169, pp. 480 - 494, http://dx.doi.org/10.1016/j.carbpol.2017.04.032
2017
Fife CM; McCarroll JA; Kavallaris M, 2017, 'Movers and shakers: cell cytoskeleton in cancer metastasis (vol 171, pg 5507, 2014)', BRITISH JOURNAL OF PHARMACOLOGY, vol. 174, pp. 116 - 116, http://dx.doi.org/10.1111/bph.13672
2017
Kunz-Schughart LA; Dubrovska A; Peitzsch C; Ewe A; Aigner A; Schellenburg S; Muders MH; Hampel S; Cirillo G; Iemma F; Tietze R; Alexiou C; Stephan H; Zarschler K; Vittorio O; Kavallaris M; Parak WJ; Mädler L; Pokhrel S, 2017, 'Nanoparticles for radiooncology: Mission, vision, challenges', Biomaterials, vol. 120, pp. 155 - 184, http://dx.doi.org/10.1016/j.biomaterials.2016.12.010
2017
Lovelace MD; Powter EE; Coleman PR; Zhao Y; Parker A; Chang GH; Lay AJ; Hunter J; McGrath AP; Jormakka M; Bertolino P; McCaughan G; Kavallaris M; Vadas MA; Gamble JR, 2017, 'The RhoGAP protein ARHGAP18/SENEX localizes to microtubules and regulates their stability in endothelial cells', Molecular Biology of the Cell, vol. 28, pp. 1066 - 1078, http://dx.doi.org/10.1091/mbc.E16-05-0285
2017
McCarroll JA, 2016, 'Stathmin mediates neuroblastoma metastasis in a tubulin-independent manner via RhoA/ROCK signaling and enhanced transendothelial migration', Oncogene, vol. 36, pp. 501 - 511, http://dx.doi.org/10.1038/onc.2016.220.
2016
Parker AL; Turner N; McCarroll JA; Kavallaris M, 2016, 'βIII-Tubulin alters glucose metabolism and stress response signaling to promote cell survival and proliferation in glucose-starved non-small cell lung cancer cells', Carcinogenesis, vol. 37, pp. 787 - 798, http://dx.doi.org/10.1093/carcin/bgw058
2016
Levrier C; Sadowski MC; Rockstroh A; Gabrielli B; Kavallaris M; Lehman M; Davis RA; Nelson CC, 2016, '6α-Acetoxyanopterine: A novel structure class of mitotic inhibitor disrupting microtubule dynamics in prostate cancer cells', Molecular Cancer Therapeutics, vol. 16, pp. 3 - 15, http://dx.doi.org/10.1158/1535-7163.MCT-16-0325
2016
Sharbeen G; McCarroll J; Liu J; Youkhana J; Limbri LF; Biankin AV; Johns A; Kavallaris M; Goldstein D; Phillips PA, 2016, 'Delineating the Role of βIV-Tubulins in Pancreatic Cancer: βIVb-Tubulin Inhibition Sensitizes Pancreatic Cancer Cells to Vinca Alkaloids', Neoplasia (United States), vol. 18, pp. 753 - 764, http://dx.doi.org/10.1016/j.neo.2016.10.011
2016
Byrne FL; McCarroll JA; Kavallaris M, 2016, 'Analyses of tumor burden in vivo and metastasis ex vivo using luciferase-expressing cancer cells in an orthotopic mouse model of neuroblastoma', RNA imaging: methods and protocols, vol. 1372, pp. 61 - 77, http://dx.doi.org/10.1007/978-1-4939-3148-4_5
2016
Pasquier E; André N; Street J; Chougule A; Rekhi B; Ghosh J; Philip DSJ; Meurer M; MacKenzie KL; Kavallaris M; Banavali SD, 2016, 'Effective Management of Advanced Angiosarcoma by the Synergistic Combination of Propranolol and Vinblastine-based Metronomic Chemotherapy: A Bench to Bedside Study', EBioMedicine, vol. 6, pp. 87 - 95, http://dx.doi.org/10.1016/j.ebiom.2016.02.026
2016
Vittorio O; Cojoc M; Curcio M; Spizzirri UG; Hampel S; Nicoletta FP; Iemma F; Dubrovska A; Kavallaris M; Cirillo G, 2016, 'Polyphenol Conjugates by Immobilized Laccase: The Green Synthesis of Dextran-Catechin', Macromolecular Chemistry and Physics, vol. 217, pp. 1488 - 1492, http://dx.doi.org/10.1002/macp.201600046
2016
Oliver S; Thomas DS; Kavallaris M; Vittorio O; Boyer C, 2016, 'Efficient functionalisation of dextran-aldehyde with catechin: potential applications in the treatment of cancer', Polymer Chemistry, vol. 7, pp. 2542 - 2552, http://dx.doi.org/10.1039/C6PY00228E
2016
Liu PY; Sokolowski N; Guo ST; Siddiqi F; Atmadibrata B; Telfer TJ; Sun Y; Zhang L; Yu D; Mccarroll J; Liu B; Yang RH; Guo XY; Tee AE; Itoh K; Wang J; Kavallaris M; Haber M; Norris MD; Cheung BB; Byrne JA; Ziegler DS; Marshall GM; Dinger ME; Codd R; Zhang XD; Liu T, 2016, 'The BET bromodomain inhibitor exerts the most potent synergistic anticancer effects with quinone-containing compounds and anti-microtubule drugs', Oncotarget, vol. 7, pp. 79217 - 79232, http://dx.doi.org/10.18632/oncotarget.12640
2016
Ercole F; Mansfeld FM; Kavallaris M; Whittaker MR; Quinn JF; Halls ML; Davis TP, 2016, 'Macromolecular Hydrogen Sulfide Donors Trigger Spatiotemporally Confined Changes in Cell Signaling', Biomacromolecules, vol. 17, pp. 371 - 383, http://dx.doi.org/10.1021/acs.biomac.5b01469
2016
Vittorio O; Brandl M; Cirillo G; Kimpton K; Hinde E; Gaus K; Yee E; Kumar N; Duong H; Fleming C; Haber M; Norris M; Boyer C; Kavallaris M, 2016, 'Dextran-Catechin: An anticancer chemically-modified natural compound targeting copper that attenuates neuroblastoma growth', Oncotarget, vol. 7, pp. 47479 - 47493, http://dx.doi.org/10.18632/oncotarget.10201
2016
McCarroll JA; Teo J; Boyer C; Youkhana J; Sagnella S; Duong H; Sharbeen G; Goldstein D; Davis T; Kavallaris M; Phillips P; Liu J, 2016, 'A rationally optimized nanoparticle system for the delivery of RNA interference therapeutics into pancreatic tumors in vivo.', Biomacromolecules, vol. 17, pp. 2337 - 2351, http://dx.doi.org/10.1021/acs.biomac.6b00185
2016
Makharza S; Vittorio O; Cirillo G; Oswald S; Hinde E; Kavallaris M; Büchner B; Mertig M; Hampel S, 2015, 'Graphene oxide - Gelatin nanohybrids as functional tools for enhanced carboplatin activity in neuroblastoma cells', Pharmaceutical Research, vol. 32, pp. 2132 - 2143, http://dx.doi.org/10.1007/s11095-014-1604-z
2015
Liu PY; Erriquez D; Marshall GM; Tee AE; Polly P; Wong M; Liu B; Bell JL; Zhang XD; Milazzo G; Cheung BB; Fox A; Swarbrick A; Hüttelmaier S; Kavallaris M; Perini G; Mattick JS; Dinger ME; Liu T, 2015, 'Erratum: Effects of a novel long noncoding RNA, lncUSMycN, on N-Myc expression and neuroblastoma progression (Journal of the National Cancer Institute (2014) 106:7 (dju113) DOI: 10.1093/jnci/dju113)', Journal of the National Cancer Institute, vol. 107, http://dx.doi.org/10.1093/jnci/dju359
2015
Pasquier E; Tuset MP; Sinnappan S; Carnell M; Macmillan A; Kavallaris M, 2015, 'γ-Actin plays a key role in endothelial cell motility and neovessel maintenance', Vascular Cell, vol. 7, http://dx.doi.org/10.1186/s13221-014-0027-2
2015
McCarroll JA; Dwarte T; Baigude H; Dang J; Yang L; Erlich RB; Kimpton K; Teo J; Sagnella SM; Akerfeldt MC; Liu J; Phillips PA; Rana TM; Kavallaris M, 2015, 'Therapeutic targeting of polo-like kinase 1 using RNA-interfering nanoparticles (iNOPs) for the treatment of non-small cell lung cancer', Oncotarget, vol. 6, pp. 12020 - 12034, http://dx.doi.org/10.18632/oncotarget.2664
2015
Kavallaris M; Po'uha S, 2015, 'Gamma-actin is involved in regulating centrosome function and mitotic progression in cancer cells', Cell Cycle, vol. 14, pp. 3908 - 3919, http://dx.doi.org/10.1080/15384101.2015.1120920
2015
McCarroll JA; Gan PP; Erlich RB; Liu M; Dwarte T; Sagnella SS; Akerfeldt MC; Yang L; Parker AL; Chang MH; Shum MS; Byrne FL; Kavallaris M, 2015, 'TUBB3/βIII-tubulin acts through the PTEN/AKT signaling axis to promote tumorigenesis and anoikis resistance in non-small cell lung cancer', Cancer Research, vol. 75, pp. 415 - 425, http://dx.doi.org/10.1158/0008-5472.CAN-14-2740
2015
McCarroll JA; Sharbeen G; Liu J; Youkhana J; Goldstein D; McCarthy N; Limbri LF; Dischl D; Ceyhan GO; Erkan M; Johns AL; Biankin AV; Kavallaris M; Phillips PA, 2015, 'βIII-Tubulin: A novel mediator of chemoresistance and metastases in pancreatic cancer', Oncotarget, vol. 6, pp. 2235 - 2249, http://dx.doi.org/10.18632/oncotarget.2946
2015
Cheung BB; Tan O; Koach J; Liu B; Shum MSY; Carter DR; Sutton S; Po'uha ST; Chesler L; Haber M; Norris MD; Kavallaris M; Liu T; O'Neill GM; Marshall GM, 2015, 'Thymosin-β4 is a determinant of drug sensitivity for Fenretinide and Vorinostat combination therapy in neuroblastoma', Molecular Oncology, vol. 9, pp. 1484 - 1500, http://dx.doi.org/10.1016/j.molonc.2015.04.005
2015
Sevimli S; Sagnella S; Macmillan A; Whan R; Kavallaris M; Bulmus V; Davis TP, 2015, 'The endocytic pathway and therapeutic efficiency of doxorubicin conjugated cholesterol-derived polymers', Biomaterials Science, vol. 3, pp. 323 - 335, http://dx.doi.org/10.1039/c4bm00224e
2015
Sagnella SM; Hien D; MacMillan A; Boyer C; Whan R; McCarroll JA; Davis TP; Kavallaris M, 2014, 'Dextran-Based Doxorubicin Nanocarriers with Improved Tumor Penetration', BIOMACROMOLECULES, vol. 15, pp. 262 - 275, http://dx.doi.org/10.1021/bm401526d
2014
Byrne FL; Yang L; Phillips PA; Hansford LM; Fletcher JI; Ormandy CJ; McCarroll JA; Kavallaris M, 2014, 'RNAi-mediated stathmin suppression reduces lung metastasis in an orthotopic neuroblastoma mouse model', Oncogene, vol. 33, pp. 882 - 890, http://dx.doi.org/10.1038/onc.2013.11
2014
Chen X; Cheng X; Soeriyadi AH; Sagnella SM; Lu X; Scott JA; Lowe SB; Kavallaris M; Gooding JJ, 2014, 'Stimuli-responsive functionalized mesoporous silica nanoparticles for drug release in response to various biological stimuli', Biomaterials Science, vol. 2, pp. 121 - 130, http://dx.doi.org/10.1039/c3bm60148j
2014
Liu PY; Erriquez D; Marshall GM; Tee AE; Polly P; Wong M; Liu B; Bell JL; Zhang XD; Milazzo G; Cheung BB; Fox A; Swarbrick A; Hüttelmaier S; Kavallaris M; Perini G; Mattick JS; Dinger ME; Liu T, 2014, 'Effects of a novel long noncoding RNA, lncUSMycN, on N-Myc expression and neuroblastoma progression', Journal of the National Cancer Institute, vol. 106, http://dx.doi.org/10.1093/jnci/dju113
2014
Vittorio O; Brandl M; Cirillo G; Spizzirri UG; Picci N; Kavallaris M; Iemma F; Hampel S, 2014, 'Novel functional cisplatin carrier based on carbon nanotubes-quercetin nanohybrid induces synergistic anticancer activity against neuroblastoma in vitro', RSC Advances, vol. 4, pp. 31378 - 31384, http://dx.doi.org/10.1039/c4ra03331k
2014
McCarroll J; Teo J; Boyer C; Goldstein D; Kavallaris M; Phillips PA, 2014, 'Potential applications of nanotechnology for the diagnosis and treatment of pancreatic cancer', Frontiers in Physiology, vol. 5, pp. 1 - 10, http://dx.doi.org/10.3389/fphys.2014.00002
2014
Vittorio O; Voliani V; Faraci P; Karmakar B; Iemma F; Hampel S; Kavallaris M; Cirillo G, 2014, 'Magnetic catechin-dextran conjugate as targeted therapeutic for pancreatic tumour cells', Journal of Drug Targeting, vol. 22, pp. 408 - 415, http://dx.doi.org/10.3109/1061186X.2013.878941
2014
Parker AL; Kavallaris M; McCarroll JA, 2014, 'Microtubules and their role in cellular stress in cancer', Frontiers in Oncology, vol. 4 JUN, http://dx.doi.org/10.3389/fonc.2014.00153
2014
Eiffe E; Pasquier E; Kavallaris M; Herbert C; Black DSC; Kumar N, 2014, 'Synthesis, anti-cancer and anti-inflammatory activity of novel 2-substituted isoflavenes', Bioorganic and Medicinal Chemistry, vol. 22, pp. 5182 - 5193, http://dx.doi.org/10.1016/j.bmc.2014.08.010
2014
Sagnella SM; McCarroll JA; Kavallaris M, 2014, 'Drug delivery: Beyond active tumour targeting', Nanomedicine: Nanotechnology, Biology, and Medicine, vol. 10, pp. 1131 - 1137, http://dx.doi.org/10.1016/j.nano.2014.04.012
2014
Chen X; Soeriyadi AH; Lu X; Sagnella SM; Kavallaris M; Gooding JJ, 2014, 'Dual bioresponsive mesoporous silica nanocarrier as an "AND" logic gate for targeted drug delivery cancer cells', Advanced Functional Materials, vol. 24, pp. 6999 - 7006, http://dx.doi.org/10.1002/adfm.201402339
2014
Brandl MB; Pasquier E; Li F; Beck D; Zhang S; Zhao H; Kavallaris M; Wong STC, 2014, 'Computational analysis of image-based drug profiling predicts synergistic drug combinations: Applications in triple-negative breast cancer', Molecular Oncology, vol. 8, pp. 1548 - 1560, http://dx.doi.org/10.1016/j.molonc.2014.06.007
2014
Kim PY; Tan O; Diakiw SM; Carter D; Sekerye EO; Wasinger VC; Liu T; Kavallaris M; Norris MD; Haber M; Chesler L; Dolnikov A; Trahair TN; Cheung NK; Marshall GM; Cheung BB, 2014, 'Identification of plasma Complement C3 as a potential biomarker for neuroblastoma using a quantitative proteomic approach', Journal of Proteomics, vol. 96, pp. 1 - 12, http://dx.doi.org/10.1016/j.jprot.2013.10.032
2014
McCarroll JA; Naim S; Sharbeen G; Russia N; Lee J; Kavallaris M; Goldstein D; Phillips PA, 2014, 'Role of pancreatic stellate cells in chemoresistance in pancreatic cancer', Frontiers in Physiology, vol. 5 APR, http://dx.doi.org/10.3389/fphys.2014.00141
2014
Fife CM; McCarroll JA; Kavallaris M, 2014, 'Movers and shakers: Cell cytoskeleton in cancer metastasis', British Journal of Pharmacology, vol. 171, pp. 5507 - 5523, http://dx.doi.org/10.1111/bph.12704
2014
Pasquier E; Tuset MP; Street J; Sinnappan SM; Mackenzie KL; Braguer D; Andre N; Kavallaris M, 2013, 'Concentration- and schedule-dependent effects of chemotherapy on the angiogenic potential and drug sensitivity of vascular endothelial cells', Angiogenesis, vol. 16, pp. 373 - 386, http://dx.doi.org/10.1007/s10456-012-9321-x
2013
Duong HTT; Kamarudin ZM; Erlich RB; Li Y; Jones MJ; Kavallaris M; Boyer CA; Davis TP, 2013, 'Intracellular nitric oxide delivery from stable NO-polymeric nanoparticle carriers', Chemical Communications, vol. 49, pp. 4190 - 4192, http://dx.doi.org/10.1039/c2cc37181b
2013
Pasquier E; Street J; Pouchy C; Carre M; Gifford AJ; Murray J; Norris MD; Trahair T; Andre N; Kavallaris M, 2013, 'B-blockers increase response to chemotherapy via direct antitumour and anti-angiogenic mechanisms in neuroblastoma', British Journal of Cancer, vol. 108, pp. 2485 - 2494, http://dx.doi.org/10.1038/bjc.2013.205
2013
Pasquier E; Trahair T; Kavallaris M; Andre N, 2013, 'Reply: Comment on 'beta-blockers increase response to chemotherapy via direct anti-tumour and anti-angiogenic mechanisms in neuroblastoma'-β- blockers are potent anti-angiogenic and chemo-sensitising agents, rather than cytotoxic drugs', British Journal of Cancer, vol. 109, pp. 2024 - 2025, http://dx.doi.org/10.1038/bjc.2013.498
2013
Sevimli S; Sagnella S; Kavallaris M; Bulmus V; Davis TP, 2013, 'Assessment of cholesterol-derived ionic copolymers as potential vectors for gene delivery', Biomacromolecules, vol. 14, pp. 4135 - 4149, http://dx.doi.org/10.1021/bm4013088
2013
Bell JL; Malyukova A; Kavallaris M; Marshall GM; Cheung BB, 2013, 'TRIM16 inhibits neuroblastoma cell proliferation through cell cycle regulation and dynamic nuclear localization', Cell Cycle, vol. 12, pp. 889 - 898, http://dx.doi.org/10.4161/cc.23825
2013
Boyer CA, 2013, 'Functionalizing biodegradable dextran scaffolds using living radical polymerization: New versatile nanoparticles for the delivery of therapeutic molecules', Molecular Pharmaceutics, vol. 9, pp. 3046 - 3061, http://dx.doi.org/10.1021/mp300144y
2013
Po'uha ST; Honore S; Braguer D; Kavallaris M, 2013, 'Partial depletion of gamma-actin suppresses microtubule dynamics', Cytoskeleton, vol. 70, pp. 148 - 160, http://dx.doi.org/10.1002/cm.21096
2013
Teo J; Erlich RB; Sagnella S; Dwarte T; Davis TP; Kavallaris M; McCarroll J; Boyer C; Duong HTT; Phillips P; Sharbeen G; Goldstein D, 2013, 'Effective delivery of siRNA into cancer cells and tumors using well-defined biodegradable cationic star polymers', Molecular Pharmaceutics, vol. 10, pp. 2435 - 2444, http://dx.doi.org/10.1021/mp400049e
2013
Basuki JS; Duong HTT; Macmillan A; Erlich RB; Esser L; Akerfeldt MC; Whan RM; Kavallaris M; Boyer C; Davis TP, 2013, 'Using Fluorescence Lifetime Imaging Microscopy to Monitor Theranostic Nanoparticle Uptake and Intracellular Doxorubicin Release', ACS NANO, vol. 7, pp. 10175 - 10189, http://dx.doi.org/10.1021/nn404407g
2013
Kan C; Wen VW; Pasquier E; Jankowski K; Chang M; Richards LA; Kavallaris M; Mackenzie K, 2012, 'Endothelial cell dysfunction and cytoskeletal changes associated with repression of p16(INK4a) during immortalization', Oncogene, vol. 31, pp. 4815 - 4827, http://dx.doi.org/10.1038/onc.2011.645
2012
Cheung BB; Koach J; Tan O; Kim P; Bell J; D'andreti C; Sutton S; Malyukova A; Sekyere E; Norris MD; Haber M; Kavallaris M; Cunningham AM; Proby C; Leigh I; Wilmott J; Cooper C; Halliday GM; Scolyer RA; Marshall GM, 2012, 'The retinoid signalling molecule, TRIM16, is repressed during squamous cell carcinoma skin carcinogenesis in vivo and reduces skin cancer cell migration in vitro', Journal of Pathology, vol. 226, pp. 451 - 462, http://dx.doi.org/10.1002/path.2986
2012
Sevimli S; Sagnella SM; Kavallaris M; Bulmus V; Davis TP, 2012, 'Synthesis, self-assembly and stimuli responsive properties of cholesterol conjugated polymers', Polymer Chemistry, vol. 3, pp. 2057 - 2069, http://dx.doi.org/10.1039/c2py20112g
2012
Bell J; Malyukova A; Holien J; Koach J; Parker M; Kavallaris M; Marshall GM; Cheung BB, 2012, 'TRIM16 acts as an E3 ubiquitin ligase and can heterodimerize with other TRIM family members', PLoS One, vol. 7, pp. Article number e37470, http://dx.doi.org/10.1371/journal.pone.0037470
2012
Failes TW; Mitic G; Abdel-halim H; Po'uha ST; Liu M; Hibbs DE; Kavallaris M, 2012, 'Evolution of Resistance to Aurora Kinase B Inhibitors in Leukaemia Cells', PLoS ONE, vol. 7, pp. e30734, http://dx.doi.org/10.1371/journal.pone.0030734
2012
Katsetos CD; Draber P; Kavallaris M, 2011, 'Targeting betaIII-tubulin in glioblastoma multiforme: From cell biology and histopathology to cancer therapeutics', Anti-Cancer Agents in Medicinal Chemistry, vol. 11, pp. 719 - 728, http://dx.doi.org/10.2174/187152011797378760
2011
Gan PP; Mccarroll J; Byrne F; Garner J; Kavallaris M, 2011, 'Specific beta-Tubulin Isotypes Can Functionally Enhance or Diminish Epothilone B Sensitivity in Non-Small Cell Lung Cancer Cells', PLoS One, vol. 6, pp. e21717, http://dx.doi.org/10.1371/journal.pone.0021717
2011
Pasquier E; Ciccolini J; Carre M; Giacometti S; Fanciullino R; Pouchy C; Montero MP; Serdjebi C; Kavallaris M; Andre N, 2011, 'Propranolol potentiates the anti-angiogenic effects and anti-tumor efficacy of chemotherapy agents: implication in breast cancer treatment.', Oncotarget, vol. 2, pp. 797 - 809, http://dx.doi.org/10.18632/oncotarget.343
2011
Wong L; Kavallaris M; Bulmus V, 2011, 'Doxorubicin conjugated, crosslinked, PEGylated particles prepared via one-pot thiol-ene modification of a homopolymer scaffold: synthesis and in vitro evaluation', Polymer Chemistry, vol. 2, pp. 385 - 393, http://dx.doi.org/10.1039/c0py00256a
2011
Schofield DJ; Meachem S; West C; Kavallaris M; Callander EJ, 2011, 'A crisis in the making? Education, ageing populations and the future of the medical research workforce', Medical Education, vol. 45, pp. 200 - 207, http://dx.doi.org/10.1111/j.1365-2923.2010.03785.x
2011
Ginu A; McCarroll J; Byrne F; Saricilar S; Kavallaris M; Bulmus V, 2011, 'Block Co-polymer Nanoparticles with Degradable Cross-Linked Core and Low-Molecular-Weight PEG Corona for Anti-tumour Drug Delivery', Journal of Biomaterials Science - Polymer Edition, vol. 22, pp. 1001 - 1022, http://dx.doi.org/10.1163/092050610X497872
2011
Shum M; Pasquier E; Po'uha ST; O'Neill GM; Chaponnier C; Gunning PW; Kavallaris M, 2011, 'γ-Actin regulates cell migration and modulates the ROCK signaling pathway', The FASEB Journal, vol. 25, pp. 4423 - 4433, http://dx.doi.org/10.1096/fj.11-185447
2011
Nakano M; Saldanha R; Gobel A; Kavallaris M; Packer NH, 2011, 'Identification of Glycan Structure Alterations on Cell Membrane Proteins in Desoxyepothilone B Resistant Leukemia Cells', Molecular and Cellular Proteomics, vol. 10, http://dx.doi.org/10.1074/mcp.M111.009001
2011
Kow SC; McCarroll J; Valade D; Boyer CA; Dwarte T; Davis TP; Kavallaris M; Bulmus V, 2011, 'Dicer-Labile PEG Conjugates for siRNA Delivery', Biomacromolecules, vol. 12, pp. 4301 - 4310, http://dx.doi.org/10.1021/bm201199c
2011
Liu T, 2010, 'TRIM16 acts as a tumour suppressor by inhibitory effects on cytoplasmic vimentin and nuclear E2F1 in neuroblastoma cells', Oncogene, vol. 29, pp. 6172 - 6183, http://dx.doi.org/10.1038/onc.2010.340
2010
Kavallaris M, 2010, 'Erratum: Microtubules and resistance to tubulin-binding agents (Nature Reviews Cancer)', Nature Reviews Cancer, vol. 10, pp. 309, http://dx.doi.org/10.1038/nrc2819
2010
Abraham G; McCaroll J; Byrne F; Saricilar S; Kavallaris M; Bulmus V, 2010, 'Block Co-polymer Nanoparticles with Degradable Cross-Linked Core and Low-Molecular-Weight PEG Corona for Anti-tumour Drug Delivery', Journal of Biomaterials Science - Polymer Edition, vol. 22, pp. 1001 - 1022, http://dx.doi.org/10.1163/092050610X497872
2010
McCarroll J; Gan PP; Liu M; Kavallaris M, 2010, 'beta III-Tubulin Is a Multifunctional Protein Involved in Drug Sensitivity and Tumorigenesis in Non-Small Cell Lung Cancer', Cancer research, vol. 70, pp. 4995 - 5003, http://dx.doi.org/10.1158/0008-5472.CAN-09-4487
2010
Kavallaris M, 2010, 'Microtubules and resistance to tubulin-binding agents', Nature Reviews Cancer, vol. 10, pp. 194 - 204, http://dx.doi.org/10.1038/nrc2803
2010
Po'uha S; Shum MSY; Goebel A; Bernard O; Kavallaris M, 2010, 'LIM-kinase 2, a regulator of actin dynamics, is involved in mitotic spindle integrity and sensitivity to microtubule-destabilizing drugs', Oncogene, vol. 29, pp. 597 - 607, http://dx.doi.org/10.1038/onc.2009.367
2010
Gan PP; McCarroll JA; Po'uha S; Kamath K; Jordan MA; Kavallaris M, 2010, 'Microtubule Dynamics, Mitotic Arrest, and Apoptosis: Drug-Induced Differential Effects of beta III-Tubulin', Molecular Cancer Therapeutics, vol. 9, pp. 1339 - 1348, http://dx.doi.org/10.1158/1535-7163.MCT-09-0679
2010
Pasquier E; Kavallaris M; Andre N, 2010, 'Metronomic chemotherapy: new rationale for new directions', Nature Reviews Clinical Oncology, vol. 7, pp. 455 - 465, http://dx.doi.org/10.1038/nrclinonc.2010.82
2010
Kavallaris M, 2010, 'Microtubules and resistance to tubulin-binding agents', Nature Reviews Cancer, http://dx.doi.org/10.1038/nrc2830
2010
Boyer CA; Priyanto P; Davis TP; Pissuwan D; Bulmus V; Kavallaris M; Teoh WY; Amal R; Carroll M; Woodward R; St pierre T, 2010, 'Anti-fouling magnetic nanoparticles for siRNA delivery', Journal of Materials Chemistry, vol. 20, pp. 255 - 265, http://dx.doi.org/10.1039/b914063h
2010
Pasquier E; Sinnappan S; Munoz M; Kavallaris M, 2010, 'ENMD-1198, a New Analogue of 2-Methoxyestradiol, Displays Both Antiangiogenic and Vascular-Disrupting Properties', Molecular Cancer Therapeutics, vol. 9, pp. 1408 - 1418, http://dx.doi.org/10.1158/1535-7163.MCT-09-0894
2010
Liu T, 2009, 'The cyclin-dependent kinase inhibitor, p21WAF1, promotes angiogenesis by repressing gene transcription of thioredoxin-binding protein 2 in cancer cells', Carcinogenesis, vol. 30, pp. 1865 - 1871, http://dx.doi.org/10.1093/carcin/bgp225
2009
Raif A; Marshall GM; Bell J; Koach J; Tan O; D'andreti C; Thomas WD; Sekyere E; Norris MD; Haber M; Kavallaris M; Cheung BB, 2009, 'The estrogen-responsive B box protein (EBBP) restores retinoid sensitivity in retinoid-resistant cancer cells via effects on histone acetylation', Cancer Letters, vol. 277, pp. 82 - 90, http://dx.doi.org/10.1016/j.canlet.2008.11.030
2009
Liaw TY; Salam N; McKay M; Cunningham AM; Hibbs D; Kavallaris M, 2008, 'Class I beta-tubulin mutations in 2-methoxyestradiol-resistant acute lymphoblastic leukemia cells: implications for drug-target interactions', Molecular Cancer Therapeutics, vol. 7, pp. 3150 - 3159, http://dx.doi.org/10.1158/1535-7163.MCT-08-0442
2008
Michaud J; Simpson KM; Escher R; Buchet-Poyau K; Beissbarth T; Carmichael CA; Ritchie M; Schutz F; Cannon P; Liu M; Shen XF; Ito Y; Raskind WH; Horwitz MS; Osato M; Turner DR; Speed TP; Kavallaris M; Smyth GK; Scott HS, 2008, 'Integrative analysis of RUNX1 downstream pathways and target genes.', BMC Genomics, vol. 8, pp. 363, http://dx.doi.org/10.1186/1471-2164-9-363
2008
Gan PP; Kavallaris M, 2008, 'Tubulin-Targeted Drug Action: Functional Significance of Class II and Class IVb beta-Tubulin in Vinca Alkaloid Sensitivity', Cancer research, vol. 68, pp. 9817 - 9824, http://dx.doi.org/10.1158/0008-5472.CAN-08-1501
2008
Chan YK; Wong TH; Byrne F; Kavallaris M; Bulmus V, 2008, 'Acid-labile core cross-linked micelles for pH-triggered release of antitumor drugs.', Biomacromolecules, vol. 9, pp. 1826 - 1836, http://dx.doi.org/10.1021/bm800043n
2008
Ong V; Liem N; Schmid M; Verrills NM; Papa R; Marshall GM; Mackenzie K; Kavallaris M; Lock RB, 2008, 'A role for altered microtubule polymer levels in vincristine resistance of childhood acute lymphoblastic leukemia xenografts', Journal of Pharmacology and Experimental Therapeutics, vol. 324, pp. 434 - 442, http://dx.doi.org/10.1124/jpet.107.128926
2008
Kavallaris M; Meachem S; Hulett M; West C; Pitt R; Chesters J; Laffan W; Boreham P; Khachigian LM, 2008, 'Perceptions in health and medical research careers: the Australian Society for Medical Research Workforce Survey', Medical Journal of Australia, vol. 188, pp. 520 - 524
2008
Pasquier E; Kavallaris M, 2008, 'Microtubules: A dynamic target in cancer therapy', IUBMB Life, vol. 60, pp. 165 - 170, http://dx.doi.org/10.1002/iub.25
2008
Kavallaris M; Annereau JP; Barret JM, 2008, 'Potential Mechanisms of Resistance to Microtubule Inhibitors', Seminars in Oncology, vol. 35, http://dx.doi.org/10.1053/j.seminoncol.2008.01.006
2008
Escher R; Wilson P; Carmichael CA; Suppiah R; Liu M; Kavallaris M; Cannon P; Michaud J; Scott HS, 2007, 'A pedigree with autosomal dominant thrombocytopenia, red cell macrocytosis, and an occurrence of t(12:21) positive pre-B acute lymphoblastic leukemia', Blood Cells Molecules and Diseases, vol. 39, pp. 107 - 114, http://dx.doi.org/10.1016/j.bcmd.2007.02.009
2007
Liaw TY; Chang MH; Kavallaris M, 2007, 'The cytoskeleton as a therapeutic target in childhood acute leukemia: obstacles and opportunities', Current Drug Targets, vol. 8, pp. 739 - 749, http://dx.doi.org/10.2174/138945007780830836
2007
Tommasi S; Mangia A; Lacalamita R; Bellizzi A; Fedele V; Chiriatti A; Thomssen C; Kendzierski N; Latorre A; Lorusso V; Schittulli F; Zito F; Kavallaris M; Paradiso A, 2007, 'Cytoskeleton and paclitaxel sensitivity in breast cancer: The role of Beta-tubulins', International Journal of Cancer, vol. 120, pp. 2078 - 2085, http://dx.doi.org/10.1002/ijc.22557
2007
Gan PP; Pasquier E; Kavallaris M, 2007, 'Class III beta-tubulin mediates sensitivity to chemotherapeutic drugs in non-small cell lung cancer', Cancer research, vol. 67, pp. 9356 - 9363, http://dx.doi.org/10.1158/0008-5472.CAN-07-0509
2007
Kavallaris M, 2007, 'Tubulin/microtubule system as an anti-cancer drug target', Current Cancer Drug Targets, vol. 7, pp. 696, http://dx.doi.org/10.2174/156800907783220444
2007
Pouha ST; Liu M; Marshall GM; Kavallaris M; Verrills NM, 2006, 'Alterations in gamma-actin and tubulin-targeted drug resistance in childhood leukemia', Journal of the National Cancer Institute, vol. 98, pp. 1363 - 1374, http://dx.doi.org/10.1093/jnci/djj372
2006
Butt A; Roberts CG; Seavvright A; Oelrichs P; Macleod JK; Liaw TY; Kavallaris M; Somers-Edgar T; Lehrbach GM; Watts CK; Sutherland RL, 2006, 'A novel plant toxin, persin, with in vivo activity in the mammary gland, induces Bim-dependent apoptosis in human breast cancer cells', Molecular Cancer Therapeutics, vol. 5, pp. 2300 - 2309, http://dx.doi.org/10.1158/1535-7163.MCT-06-0170
2006
Verrills NM; Liaw TY; Lock RB; Kavallaris M; Liem N; Hood B, 2006, 'Proteomic anlaysis reveals a novel role for the actin cytoskeleton in vincristine resistant childhood leukemia - an in vivo study', Proteomics, vol. 6, pp. 1681 - 1694, http://dx.doi.org/10.1002/pmic.200500417
2006
Cheung BB; Bell J; Raif A; Bohlken A; Yan J; Poljak A; Smith S; Lee M; Thomas WD; Kavallaris M; Norris MD; Haber M; Liu H; Zajchowski D; Marshall GM; bell , 2006, 'The estrogen-responsive B box protein is a novel regulator of the retinoid signal', The Journal of Biological Chemistry, vol. 281, pp. 18246 - 18256, http://dx.doi.org/10.1074/jbc.M600879200
2006
Chan YK; Bulmus V; Zareie MH; Barner L; Kavallaris M; Byrne F, 2006, 'Acid-Cleavable polymeric core-shell particles for delivery of hydrophoblic drugs', Journal of Controlled Release, vol. 115, pp. 197 - 207, http://dx.doi.org/10.1016/j.jconrel.2006.07.025
2006
Kavallaris M, 2006, 'Discovering novel strategies for antimicrotubule cytotoxic therapy', EJC Supplements, vol. 4, pp. 3 - 9, http://dx.doi.org/10.1016/j.ejcsup.2006.03.004
2006
Kavallaris M; Marshall GM, 2005, 'Proteomics and disease: opportunities and challenges', Medical Journal of Australia, vol. 182, pp. 575 - 579
2005
Schevzov G; Vrhovski B; Bryce N; Elmir S; Qiu M; O''neill G; Yang N; Verrills N; Kavallaris M; Gunning P, 2005, 'Tissue-specific tropomyosin isoform composition.', Histochemical Journal, vol. 53, pp. 557 - 570, http://dx.doi.org/10.1369/jhc.4A6505.2005
2005
Verrills NM; Kavallaris M, 2005, 'Improving the targeting of tubulin-binding agents: lessons from drug resistance studies.', Current Pharmaceutical Design, vol. 11, pp. 1719 - 1733, http://dx.doi.org/10.2174/1381612053764706
2005
Verrills NM; Kavallaris M, 2005, 'Improving the targeting of tubulin-binding agents: lessons from drug resistance studies', Current Pharmaceutical Design, vol. 11, pp. 1719 - 1733
2005
Don S; Verrills NM; Liaw T; Haber M; Norris MD; Kavallaris M, 2004, 'Neuronal-associated microtubule proteins class III B-tubulin and MAP2c in neuroblastoma: Role in resistance to microtubule-targeted drugs.', Molecular Cancer Therapeutics, vol. 3, pp. 1137 - 1146
2004
Verrills NM; Flemming C; Liu M; Ivery M; Cobon GS; Norris MD; Haber M; Kavallaris M, 2003, 'Microtubule alterations and mutations induced by desoxyepothilone B: Implications for drug-target', Chemistry and biology, vol. 10, pp. 597 - 607, http://dx.doi.org/10.1016/S1074-5521(03)00141-8
2003
Cheung BB; Yan JX; Smith SA; Nguyen TG; Lee M; Kavallaris M; Norris MD; Haber M; Marshall GM, 2003, 'Growth inhibitory retinoid effects after recruitment of retinoid X receptor B to the retinoic acid receptor B promoter', International Journal of Cancer, vol. 105, pp. 856 - 867, http://dx.doi.org/10.1002/ijc.11153
2003
Burkhart CA; Cheng AJ; Madafiglio J; Kavallaris M; Mili M; Marshall GM; Weiss WA; Khachigian LM; Norris MD; Haber M, 2003, 'Effects of MYCN antisense oligonucleotide administration on tumorigenesis in a murine model of neuroblastoma', Journal of National Cancer Institute, vol. 95, pp. 1394 - 1403, http://dx.doi.org/10.1093/jnci/djg045
2003
Verrills NM; Kavallaris M, 2003, 'Drug Resistance Mechanisms in Cancer Cells: A Proteomics Perspective', Current Opinion in Molecular Therapeutics, vol. 5, pp. 258 - 265
2003
Verrills NM; Walsh B; Cobons GS; Hains P; Kavallaris M, 2003, 'Proteome analysis of vinca alkaloid response and resistance in acute lymphoblastic leukaemia reveals novel cytoskeletal alternations', The Journal of Biological Chemistry, vol. 278, pp. 45082 - 45093, http://dx.doi.org/10.1074/jbc.M303378200
2003
Kavallaris M; Verrills NM; Hill B, 2002, 'Anticancer therapy with novel tubulin-interacting drugs', Drug Resistance Updates, vol. 4, pp. 392 - 401, http://dx.doi.org/10.1054/drup.2002.0230
2002
Don S; Kavallaris M, 2002, 'Microtubule alterations and resostance to tubulin-binding agents', International Journal of Oncology, vol. 21, pp. 621 - 628
2002
Tait AS; Kavallaris M; etievant C; Unkown A; Barret J; Hill B, 2001, 'Markedly diminished drug-resistance including properties of vinflunine (20`, 20`- difluro- 3`, 4` - dihydrovinorelbine) relative tovinorelbine, identified in murine and human tumour cells in vivo and in vitro, with clinical implications', Cancer Chemotherapy and Pharmacology, vol. 48, pp. 62 - 70, http://dx.doi.org/10.1007/s002800100275
2001
Kavallaris M; Tait AS; Norris MD; Haber M; Walsh B; He L; Horwitz SB, 2001, 'Multiple microtubule alterations are associated with vinca alkaloid resistance in human leukemia cells', Cancer research, vol. 61, pp. 5803 - 5809
2001
Kavallaris M; Burkhart CA; Horwitz SB, 2001, 'The role of beta-tubulin isotypes in resistance to antimitotic drugs', Biochimica et Biophysica ACTA, vol. 1471, pp. 1 - 9, http://dx.doi.org/10.1016/S0304-419X(00)00022-6
2001
Murphy KD; Ranganathan V; Farnsworth ML; Kavallaris M; Lock RB, 2000, 'Bcl-2 inhibits Bax translocation from cytosol to mitochondria during drug-induced apoptosis of human tumour cells', Cell death and differentiation, vol. 7, pp. 102 - 111, http://dx.doi.org/10.1038/sj.cdd.4400597
2000
Haber M; Bordow SB; Gilbert J; Madafiglio J; Kavallaris M; Marshall GM; Mechetner EB; Fruehauf JP; Tee L; Cohn S; Salwen H; Schmidt ML; Norris MD; Gilbert J, 1999, 'Altered expression of the MYCN Oncogene modulates MRP gene expression and response to cytotoxic drugs in neuroblastoma cells', Oncogene, vol. 18, pp. 2777 - 2782, http://dx.doi.org/10.1038/sj.onc.1202859
1999
Kavallaris M; Burkhart CA; Horwitz SB, 1999, 'Antisense oligonucleotides to class III B-tubulin sensitise drug-resistant cells to Taxol.', British Journal of Cancer, vol. 80, pp. 1020 - 1025, http://dx.doi.org/10.1038/sj.bjc.6690507
1999
Gifford AJ; Kavallaris M; Madafiglio J; Matherly LH; Stewart BW; Haber M; Norris MD, 1998, 'P-glycoprotein-mediated methotrexate resistance in CCRF-CEM sublines deficient in Methotrexate accumulation due to a point mutation in the reduced folate carrier gene', International Journal of Cancer, vol. 78, pp. 176 - 181, http://dx.doi.org/10.1002/(SICI)1097-0215(19981005)78:2<176::AID-IJC10>3.0.CO;2-9
1998
Kavallaris M; Gardaneh M; Cheung BB; Camacho M; Hocker JE; Norris MD; Haber M; Marshall GM, 1998, 'In Vitro effects of MYCN sense and antisense expression in MYCN-amplified human neuroblastoma cells', Anticancer Research, vol. 18, pp. 1793 - 1798
1998
Kavallaris M, 1997, 'The role of multidrug resistance-associated protein (MRP) expression in multidrug resistance', Anti-Cancer Drugs, vol. 8, pp. 17 - 25, http://dx.doi.org/10.1097/00001813-199701000-00002
1997
Kavallaris M; Kuo DY; Burkhart CA; Regl DL; Norris MD; Haber M; Horwitz SB, 1997, 'TAXOL-RESISTANT EPITHELIAL OVARIAN TUMORS ARE ASSOCIATED WITH ALTERED EXPRESSION OF SPECIFIC {BETA}-TUBLIN ISOTYPES', Journal of Clinical Investigation, vol. 100, pp. 1282 - 1293, http://dx.doi.org/10.1172/JCI119642
1997
Norris MD; Bordow SB; Haber PS; Marshall GM; Kavallaris M; Madafiglio J; Cohn S; Schmidt ML; Hipfner DR; Deeley RG; Cole SP; Haber M; Salwen H, 1997, 'EVIDENCE THAT THE N-MYC ONCOGENE REGULATES MRP GENE EXPRESSION IN NEUROBLASTOMA', European Journal of Cancer, vol. 33, pp. 1911 - 1916, http://dx.doi.org/10.1016/S0959-8049(97)00284-0
1997
Kavallaris M; Leary JA; Barrett JA; Friedlander ML, 1996, 'MDR1 and multidrug resistance-associated protein (MRP) gene expression in epithelial ovarian tumors', Cancer Letters, vol. 102, pp. 7 - 16, http://dx.doi.org/10.1016/0304-3835(96)04143-2
1996
Norris MD; De Graaf D; Haber M; Kavallaris M; Madafiglio J; Gilbert J; Kwan E; Stewart BW; Mechetner EB; Gudkov AV; Roninson IB, 1996, 'Involvement of MDR1 P-Glycoprotein in multifactorial resistance to methotrexate', International Journal of Cancer, vol. 65, pp. 613 - 619, http://dx.doi.org/10.1002/(SICI)1097-0215(19960301)65:5<613::AID-IJC10>3.0.CO;2-8
1996
Haber M; Norris MD; Kavallaris M; Camacho M; Madafiglio J; Baker C; White L; Stewart BW, 1995, 'An assay for the determination of reduced methotrexate accumulation in cells displaying limited viability in vitro', Cancer Letters, vol. 97, pp. 49 - 55, http://dx.doi.org/10.1016/0304-3835(95)03950-2
1995
Norris MD; Haber M; Gilbert J; Kavallaris M; Marshall GM; Stewart BW, 1994, 'N-myc gene amplification in neuroblastoma determined by the polymerase chain reaction.', Progress in clinical and biological research, vol. 385, pp. 27 - 33
1994
Pittman SM; Kavallaris M; Stewart BW, 1993, 'Karyotypic analysis of CCRF-CEM and drug-resistant cell lines with stable and unstable ploidy', Cancer Genetics and Cytogenetics, vol. 66, pp. 54 - 62, http://dx.doi.org/10.1016/0165-4608(93)90149-G
1993
Kavallaris M; Madafiglio J; Norris MD; Haber M, 1993, 'Resistance to Tetracycline, a Hydrophilic Antibiotic, Is Mediated by P-Glycoprotein in Human Multidrug-Resistant Cells', Biochemical and Biophysical Research Communications, vol. 190, pp. 79 - 85, http://dx.doi.org/10.1006/bbrc.1993.1013
1993
Gilbert J; Norris MD; Haber M; Kavallaris M; Marshall GM; Stewart BW, 1993, 'Determination of n-myc gene amplification in neuroblastoma by differential polymerase chain reaction', Molecular and Cellular Probes, vol. 7, pp. 227 - 234, http://dx.doi.org/10.1006/mcpr.1993.1033
1993
TELFORD DJ; KAVALLARIS M; WHITE L; NORRIS MD; BRIAN MJ; STEWART BW, 1992, 'Association of N‐myc amplification with neuroblastoma: The Australian and New Zealand experience', Journal of Paediatrics and Child Health, vol. 28, pp. 58 - 63, http://dx.doi.org/10.1111/j.1440-1754.1992.tb02619.x
1992
Kavallaris M; Haber M; Norris MD; Matherly LH; Stewart BW, 1991, 'Characterization of Mechanisms Mediating Drug Resistance in Human Leukemic Cells Selected with High Concentration Methotrexate', Pteridines, vol. 3, pp. 119 - 121, http://dx.doi.org/10.1515/pteridines.1991.3.12.119
1991
Norris MD; Haber M; Kavallaris M; Brian MJ; Lutze LH; White L; Stewart BW, 1991, 'Reduced drug accumulation as the mechanism of extreme clinical resistance to methotrexate in the human T‐cell leukemia xenograft, LALW‐2', Cancer, vol. 68, pp. 981 - 987, http://dx.doi.org/10.1002/1097-0142(19910901)68:5<981::AID-CNCR2820680512>3.0.CO;2-W
1991
Stewart BW; Kavallaris M; Catchpoole D; Norris MD, 1991, 'Two classes of single-stranded regions evident in deproteinized preparations of replicating DNA isolated from mammalian cells', Experimental Cell Research, vol. 192, pp. 639 - 642, http://dx.doi.org/10.1016/0014-4827(91)90087-B
1991
Kavallaris M; Haber M; Norris MD; Pittman SM; Reed C; Stewart BW, 1990, 'Phenotypic and cytogenetic analysis of atypical multidrug resistance in human leukaemic cells selected with methotrexate at high concentration', Cancer Letters, vol. 51, pp. 193 - 201, http://dx.doi.org/10.1016/0304-3835(90)90102-4
1990
Haber M; Reed C; Kavallaris M; Norris MD; Stewart BW, 1989, 'Resistance to drugs associated with the multidrug resistance phenotype following selection with high-concentration methotrexate', Journal of the National Cancer Institute, vol. 81, pp. 1250 - 1254, http://dx.doi.org/10.1093/jnci/81.16.1250
1989
Haber M; Norris MD; Kavallaris M; White L; Stewart BW; Bell DR; Davey RA, 1989, 'Atypical Multidrug Resistance in a Therapy-induced Drug-resistant Human Leukemia Cell Line (LALW-2): Resistance to Vinca Alkaloids Independent of P-Glycoprotein', Cancer Research, vol. 49, pp. 5281 - 5287
1989
Haber M; Kavallaris M; Stewart BW, 1986, 'Two-stage incorporation of thymidine triphosphate into mammalian DNA as indicated by chromatography on benzoylated DEAE-cellulose', Journal of Chromatography - Biomedical Applications, vol. Vol. 382, pp. 127 - 134
1986
HABER M; KAVALLARIS M; STEWART BW, 1986, '2-STAGE INCORPORATION OF THYMIDINE TRIPHOSPHATE INTO MAMMALIAN DNA AS INDICATED BY CHROMATOGRAPHY ON BENZOYLATED DEAE-CELLULOSE', JOURNAL OF CHROMATOGRAPHY, vol. 382, pp. 127 - 134, http://dx.doi.org/10.1016/S0378-4347(00)83511-2
1986
Haber M; Kavallaris M; Stewart BW, 1986, 'Two-stage incorporation of thymidine triphosphate into mammalian DNA as indicated by chromatography on benzoylated DEAE-cellulose', Journal of Chromatography B: Biomedical Sciences and Applications, vol. 382, pp. 135 - 145, http://dx.doi.org/10.1016/S0378-4347(00)83512-4
1986
Conference Abstracts
add
Voli F; Lerra L; Kimpton K; Saletta F; Shen S; Cirillo G; Kavallaris M; Vittorio O, 2019, 'Copper homeostasis: A new player in anti-tumor immune response', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Atlanta, GA, Vol. 79, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), Atlanta, GA, 29 March 2019 - 03 April 2019, http://dx.doi.org/10.1158/1538-7445.SABCS18-3224
2019
Pascali G; Parmar A; Voli F; Lerra L; Lee E; Ahmed-Cox A; Kimpton K; Cirillo G; Arthur A; Zahra D; Rahardjo G; Liu G; Lengkeek N; Pellegrini P; Saletta F; Charil A; Kavallaris M; Vittorio O, 2019, '[Cu-64]CuCl2 PET metallomics for determining the anticancer mechanism of novel drug Dextran-Catechin', in JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, WILEY, Vol. 62, pp. S526 - S527, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000468965200440&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2019
Voli F; Lerra L; Kimpton K; Saletta F; Cirillo G; Kavallaris M; Vittorio O, 2018, 'Harnessing copper in cancer to enhance anti-tumor immune response', in ANNALS OF ONCOLOGY, OXFORD UNIV PRESS, Geneva, SWITZERLAND, Vol. 29, pp. 35 - 35, presented at ESMO Immuno-Oncology Congress, Geneva, SWITZERLAND, 13 December 2018 - 16 December 2018, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000459294800106&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2018
Yee EMH; Brandl MB; Pasquier E; Cirillo G; Kimpton K; Kavallaris M; Kumar N; Vittorio O, 2017, 'Dextran-Catechin inhibits angiogenesis by disrupting copper homeostasis in endothelial cells', in Scientific Reports, Vol. 7, http://dx.doi.org/10.1038/s41598-017-07452-w
2017
Parmar A; Vittorio O; Charil A; Kavallaris M; Pascali G, 2016, 'Imaging neuroblastoma xenograft using [Cu-64]CuCl2 for evaluation of novel treatment based on Dextran/Catechin conjugate', in EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, SPRINGER, Barcelona, SPAIN, Vol. 43, pp. S480 - S480, presented at Annual Congress of the European-Association-of-Nuclear-Medicine, Barcelona, SPAIN, 15 October 2016 - 19 October 2016, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000391802400670&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2016
Boyer C; Teo J; Phillips P; Erlich RB; Sagnella S; Sharbeen G; Dwarte T; Duong HTT; Goldstein D; Davis TP; Kavallaris M; McCarroll J, 2015, 'Correction to "effective delivery of siRNA into cancer cells and tumors using well-defined biodegradable cationic star polymers"', in Molecular Pharmaceutics, Vol. 12, pp. 1004, http://dx.doi.org/10.1021/acs.molpharmaceut.5b00092
2015
Sharbeen G; McCarroll J; Liu J; Youkhana J; Goldstein D; Kavallaris M; Phillips P, 2015, 'beta III-Tubulin Regulates Sensitivity to Nab-Paclitaxel (Abraxane (R)) in Pancreatic Cancer', in PANCREAS, LIPPINCOTT WILLIAMS & WILKINS, Vol. 44, pp. 1414 - 1415, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000363324000260&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2015
Sharbeen G; Liu J; McCarroll J; Limbri L; Youkhana J; Goldstein D; Kavallaris M; Phillips P, 2015, 'beta IVb-Tubulin is a Novel Therapeutic Target for the Treatment of Pancreatic Cancer', in PANCREAS, LIPPINCOTT WILLIAMS & WILKINS, Vol. 44, pp. 1414 - 1414, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000363324000259&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2015
Kavallaris M, 2014, 'MICROTUBULE TARGETS IN CANCER: POTENTIAL OF NANOTECHNOLOGY-BASED THERAPEUTICS', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY-BLACKWELL, Vol. 10, pp. 19 - 19, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000344745100038&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
2014
Yi H; Wang J; Kavallaris M; Wang JY, 2014, 'The identification of novel targets in beta-catenin-driven acute myeloid leukemic stem cells', in EUROPEAN JOURNAL OF CANCER, ELSEVIER SCI LTD, Vol. 50, pp. S50 - S50, http://dx.doi.org/10.1016/S0959-8049(14)50188-8
2014
Kavallaris M; Kimpton K; Brandl M; Gobel A; Erlich R; Dwarte T; Mccarthy N; Sagnella S; Graham M; French P; Mccarroll J, 2013, 'SILENCING THE TUBB3 GENE IN VIVO SENSITISES NON-SMALL CELL LUNG CANCER TO CISPLATIN', in JOURNAL OF THORACIC ONCOLOGY, LIPPINCOTT WILLIAMS & WILKINS, Vol. 8, pp. S773 - S773, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000339624903299&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2013
Maritz M; Cowley MJ; Kaplan W; Kavallaris M; MacKenzie KL, 2012, 'Repression of Essential Telomerase Components Mediates Anti-proliferative Effects in Isogenic Immortal and Tumorigenic Cells, but not Normal Cells', in EUROPEAN JOURNAL OF CANCER, ELSEVIER SCI LTD, Barcelona, SPAIN, Vol. 48, pp. S79 - S80, presented at 22nd Biennial Congress of the European-Association-for-Cancer-Research, Barcelona, SPAIN, 07 July 2012 - 10 July 2012, http://dx.doi.org/10.1016/S0959-8049(12)71017-1
2012
Byrne FL; Phillips PA; Hansford LM; Fletcher JI; Ormandy CJ; McCarroll JA; Kavallaris M, 2012, 'Stathmin suppression influences ROCK signaling and reduces cell invasion and metastasis in neuroblastoma', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Vol. 72, http://dx.doi.org/10.1158/1538-7445.AM2012-1444
2012
Mitic G; Tsoli M; Ziegler DS; Kavallaris M, 2012, 'beta III-TUBULIN AND GLIOBLASTOMA: ROLE IN DRUG RESISTANCE AND TUMOURIGENESIS', in ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, WILEY-BLACKWELL, Vol. 8, pp. 303 - 304, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000310544400264&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
2012
Failes T; Mitic G; Kavallaris M, 2011, 'Identifying the mechanisms of action and resistance to the novel multi-kinase inhibitor ENMD-2076 in leukemia', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Vol. 71, http://dx.doi.org/10.1158/1538-7445.AM2011-730
2011
Ciccolini J; Pasquier E; Fanciullino R; Serdjebi C; Mas C; Giacometti S; Kavallaris M; Andre N, 2011, 'Drug repositioning: Propanolol potentiates the anticancer efficacy of chemotherapeutic agents through modulation of angiogenesis', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Vol. 71, http://dx.doi.org/10.1158/1538-7445.AM2011-2555
2011
Liu J; McCarroll J; Apte MV; Youkhana J; Kavallaris M; Phillips PA, 2010, 'Beta III- and beta IVb-tubulin mediate sensitivity to chemotherapeutic drugs in pancreatic cancer cells', in JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, WILEY-BLACKWELL PUBLISHING, INC, Vol. 25, pp. A76 - A76, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000283321200206&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2010
Liu J; McCarroll J; Apte MV; Youkhana J; Kavallaris M; Phillips PA, 2010, 'Beta III- and Beta IVB-Tubulin Mediate Sensitivity to Chemotherapeutic Drugs in Pancreatic Cancer Cells', in PANCREAS, LIPPINCOTT WILLIAMS & WILKINS, Vol. 39, pp. 1330 - 1330, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000282946600138&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2010
Gan PP; Kamath K; Jordan MA; Kavallaris M, 2009, 'Differential effects of \#946;III-tubulin on drug-induced microtubule dynamics and mitotic arrest', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Vol. 69, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000209702604318&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
2009
McCarroll J; Gan PP; Kavallaris M, 2009, 'Novel role of \#946;III-tubulin in tumorigenesis and drug sensitivity in non-small cell lung cancer', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Vol. 69, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000209701801261&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2009
Chang MHY; Engelander J; Verrills NM; Tait AS; Kavallaris M, 2006, 'Differential proteomic analysis of low-level anti-microtubule resistance in acute lymphoblastic leukaemia', in EJC SUPPLEMENTS, PERGAMON-ELSEVIER SCIENCE LTD, Vol. 4, pp. 57 - 57, http://dx.doi.org/10.1016/S1359-6349(06)70187-2
2006
STEWART BW; KAVALLARIS M; SMITH GJ; HABER M, 1985, 'MONITORING REPAIR AND REPLICATIVE-INDUCED STRUCTURAL-CHANGE IN CULTURES OF PROLIFERATING MAMMALIAN-CELLS', in MEDICAL AND PEDIATRIC ONCOLOGY, WILEY-LISS, Vol. 13, pp. 135 - 135, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1985AHS3500014&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
1985
Book Chapters
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McCarroll JA; Sharbeen G; Kavallaris M; Phillips PA, 2019, 'The use of star polymer nanoparticles for the delivery of siRNA to mouse orthotopic pancreatic tumor models', in Methods in Molecular Biology, United States, pp. 329 - 353, http://dx.doi.org/10.1007/978-1-4939-9220-1_23
2019
Mansfeld FM; Davis TP; Kavallaris M, 2017, 'Nanotechnology in Medical Research', in Skwarczynski M; Toth I (ed.), Micro- and Nanotechnology in Vaccine Development, William Andrew Elsevier, Oxford, UK, pp. 21 - 45, http://dx.doi.org/10.1016/B978-0-323-39981-4.00002-6
2017
Pasquier E; Kavallaris M; Andre N, 2014, 'Metronomic chemotherapy regimens using Microtubule-targeting agents: Mechanisms of action, preclinical activity and future developments', in Metronomic Chemotherapy: Pharmacology and Clinical Applications, pp. 69 - 90, http://dx.doi.org/10.1007/978-3-662-43604-2_5
2014
Erlich RB; Kavallaris M; McCarroll J; Phillips P, 2013, 'Nanotechnology, tumour biomarkers and RNA interference for personalized medicine applications', in Shiddiky MJA; Wee EJH; Rauf S; Trau M (ed.), Microfluidics, Nanotechnology and Disease Biomarkers for Personalized Medicine Applications, Nova Science Publishers, pp. 167 - 187
2013
Vittorio O; Kavallaris , 2013, 'Polyphenol Conjugate: Synthesis and Potential Biomedical Applications', in Recent Advances in Drug Delivery Research, Nova Science Publishers, USA
2013
McCarroll JA; Kavallaris M, 2012, 'Microtubules, drug resistance, and tumorigenesis', in Cytoskeleton and Human Disease, pp. 223 - 240, http://dx.doi.org/10.1007/978-1-61779-788-0_12
2012
Haber M; Kavallaris M, 2000, 'Multidrug Resistance Genes in Neuroblastoma', in Neuroblastoma, edn. Original, Elsevier Science BV, Amsterdam, pp. 207 - 215
2000
Creative Works (non-textual)
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Bailey BJ; Lilja A; Strong C; Moline K; Kavallaris M; Hughes RT; McGhee J, 2019, Multi-user immersive virtual reality prototype for collaborative visualization of microscopy image data, The 17th International Conference on Virtual-Reality Continuum and its Applications in Industry, 14 November 2019 - 16 November 2019
2019
Conference Posters
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Branchaud D; Muskovic W; Kavallaris M; Filonik D; Bednarz T, 2018, 'Visual microscope for massive genomics datasets, expanded perception and interaction', Vancouver, Canada, presented at SIGGRAPH 2018, Vancouver, Canada, 12 August 2018 - 16 August 2018, http://dx.doi.org/10.1145/3230744.3230745
2018
Conference Papers
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Parker AL; Teo WS; McCarroll JA; Kavallaris M, 2017, 'Structural domains of ss III-Tubulin regulate multiple stress responses and influence cell growth and survival in glucose-deprived non-small cell lung cancer', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Washington, DC, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), Washington, DC, 01 April 2017 - 05 April 2017, http://dx.doi.org/10.1158/1538-7445.AM2017-5484
2017
Teo WS; Dwarte T; Failes TW; Arndt GM; McCarroll JA; Kavallaris M, 2017, 'High throughput kinase inhibitor screen reveals novel inhibitor combinations acting in synergy with TUBB3/beta III-tubulin suppression in non-small cell lung cancer', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Washington, DC, presented at Annual Meeting of the American-Association-for-Cancer-Research (AACR), Washington, DC, 01 April 2017 - 05 April 2017, http://dx.doi.org/10.1158/1538-7445.AM2017-4037
2017
Vittorio O; Brandl M; Cirillo G; Kimpton K; Hinde E; Duong HTT; Boyer C; Flemming C; Yee EMH; Kumar N; Parmar A; Pascali G; Charil A; Haber M; Norris M; Kavallaris M, 2016, 'Dextran-Catechin conjugate: An anticancer nano-modified natural compound targeting copper metabolism in neuroblastoma', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, New Orleans, LA, presented at AACR 107th Annual Meeting on Bioinformatics and Systems Biology, New Orleans, LA, 16 April 2016 - 20 April 2016, http://dx.doi.org/10.1158/1538-7445.AM2016-1340
2016
Kao FCL; Failes T; Arndt GM; Norris M; Kavallaris M, 2015, 'Discovery of a small molecule TUBB3/beta III-tubulin modulator in lung cancer', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Philadelphia, PA, presented at 106th Annual Meeting of the American-Association-for-Cancer-Research (AACR), Philadelphia, PA, 18 April 2015 - 22 April 2015, http://dx.doi.org/10.1158/1538-7445.AM2015-3660
2015
Nakano M; Shirai R; Ito J; Kavallaris M; Packer N, 2014, 'Acquired drug resistance by decrease of sialylated glycans on acute lymphoblastic leukemia cell-membrane glycoproteins', in GLYCOBIOLOGY, OXFORD UNIV PRESS INC, Honolulu, HI, pp. 1217 - 1217, presented at Joint Meeting of the Society-for-Glycobiology (SFG) and the Japanese-Society-of-Carbohydrate-Research (JSCR), Honolulu, HI, 16 November 2014 - 19 November 2014, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000344670300365&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
2014
Teo J; Boyer C; Sharbeen G; Sagnella S; Liu J; Youkhana J; Duong HT; Goldstein D; Davis TP; Kavallaris M; McCarroll J; Phillips PA, 2014, 'Design and Synthesis of Novel PEGylated Star Nanoparticles as Delivery Agents for Short-Interfering RNA (siRNA) to Pancreatic Cancer Cells', in PANCREAS, LIPPINCOTT WILLIAMS & WILKINS, pp. 1416 - 1416, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000344362600356&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2014
Parker A; McCarroll JA; Kavallaris M, 2014, 'beta III-Tubulin and cell survival: Novel role in endoplasmic reticulum stress and autophagy in non-small cell lung cancer', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, San Diego, CA, presented at 105th Annual Meeting of the American-Association-for-Cancer-Research (AACR), San Diego, CA, 05 April 2014 - 09 April 2014, http://dx.doi.org/10.1158/1538-7445.AM2014-326
2014
McCarroll JA; Gan PP; Erlich RB; Liu M; Dwarte T; Akerfeldt MC; Chang M; Shum MS; Byrne F; Kavallaris M, 2014, 'beta III-tubulin is required for the tumorigenic phenotype and resistance to anoikis via the PTEN/AKT signaling axis in non-small cell lung cancer', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, San Diego, CA, presented at 105th Annual Meeting of the American-Association-for-Cancer-Research (AACR), San Diego, CA, 05 April 2014 - 09 April 2014, http://dx.doi.org/10.1158/1538-7445.AM2014-2076
2014
Fife CM; Byrne FL; Sagnella SM; Davis TP; McCarroll JA; Kavallaris M, 2014, 'Stathmin regulates cell migration, invasion and transendothelial migration via RhoA activation in neuroblastoma', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, San Diego, CA, presented at 105th Annual Meeting of the American-Association-for-Cancer-Research (AACR), San Diego, CA, 05 April 2014 - 09 April 2014, http://dx.doi.org/10.1158/1538-7445.AM2014-4987
2014
Sharbeen G; Liu J; Mccarroll J; Youkhana J; Teo J; Mccarthy N; Goldstein D; Kavallaris M; Phillips PA, 2013, 'beta III-tubulin is a novel therapeutic target for the treatment of pancreatic cancer', in JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, WILEY-BLACKWELL, pp. 12 - 12, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000324106900022&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2013
Sharbeen G; Liu J; McCarroll J; Youkhana J; Teo J; McCarthy N; Goldstein D; Kavallaris M; Phillips PA, 2013, 'beta III-Tubulin is a Novel Therapeutic Target for the Treatment of Pancreatic Cancer', in PANCREAS, LIPPINCOTT WILLIAMS & WILKINS, pp. 1381 - 1381, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000330468400204&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2013
Teo J; Boyer C; Liu J; Sharbeen G; Erlich R; Youkhana J; Duong HT; Goldstein D; Davis TP; Kavallaris M; McCarroll J; Phillips PA, 2013, 'Inhibition of beta III-Tubulin Using a Novel Nanoparticle-siRNA Approach Sensitizes Pancreatic Cancer Cells to Chemotherapy', in PANCREAS, LIPPINCOTT WILLIAMS & WILKINS, pp. 1385 - 1385, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000330468400222&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2013
Yi H; Wang J; Kavallaris M; Wang JY, 2013, 'Lgr4-Mediated Potentiation Of Wnt/beta-Catenin Signaling Promotes MLL Leukemogenesis Via An Rspo3/Wnt3a-Gnaq Pathway In Leukemic Stem Cells', in BLOOD, AMER SOC HEMATOLOGY, New Orleans, LA, presented at 55th Annual Meeting of the American-Society-of-Hematology, New Orleans, LA, 07 December 2013 - 10 December 2013, http://dx.doi.org/10.1182/blood.V122.21.887.887
2013
Liu PY; Tee A; Marshall G; Polly P; Wong M; Ling D; Kavallaris M; Perini G; Dinger ME; Liu T, 2013, 'Linc367, a novel long intergenic noncoding RNA, up-regulates N-Myc gene expression and neuroblastoma cell proliferation', in EUROPEAN JOURNAL OF CANCER, ELSEVIER SCI LTD, Amsterdam, NETHERLANDS, pp. S356 - S356, presented at European Cancer Congress 2013 - 17th ECCO / 38th ESMO / 32nd ESTRO, Amsterdam, NETHERLANDS, 27 September 2013 - 01 October 2013, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000326843602302&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2013
Mitic G; Tsoli M; Ziegler DS; Kavallaris M, 2013, 'beta III-tubulin in glioblastoma: An emerging multifactorial survival factor role in chemotherapy response and tumor formation.', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Washington, DC, presented at 104th Annual Meeting of the American-Association-for-Cancer-Research (AACR), Washington, DC, 06 April 2013 - 10 April 2013, http://dx.doi.org/10.1158/1538-7445.AM2013-3431
2013
Hien D; Hughes F; Sagnella S; Kavallaris M; Hook J; Davis TP; Boyer C, 2012, 'Biodegradable and acid labile dextran-based nanoparticles for doxorubicin delivery', in ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, AMER CHEMICAL SOC, Philadelphia, PA, presented at 244th National Fall Meeting of the American-Chemical-Society (ACS), Philadelphia, PA, 19 August 2012 - 23 August 2012, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000324621808165&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2012
Kavallaris M, 2011, 'TARGETING DRUG RESISTANCE IN LUNG CANCER', in JOURNAL OF GENE MEDICINE, WILEY-BLACKWELL, Univ Melbourne, Bio21 Inst, Parkville, AUSTRALIA, pp. 415 - 416, presented at 7th Biennial Meeting of the Australasian-Gene-Therapy-Society, Univ Melbourne, Bio21 Inst, Parkville, AUSTRALIA, 04 May 2011 - 06 May 2011, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000297950900015&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
2011
McCarroll JA; Gan PP; Liu M; Dwarte T; Chang M; Byrne F; Kavallaris M, 2010, 'beta III-Tubulin regulates expression of proteins involved in tumorigenesis and metastasis in non-small cell lung cancer', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, http://dx.doi.org/10.1158/1538-7445.AM10-5026
2010
McCarroll JA; Gan PP; Liu M; Dwarte T; Chang M; Byrne F; Kavallaris M, 2010, 'beta III-Tubulin regulates expression of proteins involved in tumorigenesis and metastasis in non-small cell lung cancer', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000209823904149&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2010
Bell JL; Cheung BB; D'Andreti C; Koach J; Raif A; Thomas WD; Norris M; Haber M; Kavallaris M; Marshall GM, 2008, 'The role of the estrogen-responsive B box protein (EBBP) in cancer cell cycle progression', in EJC SUPPLEMENTS, PERGAMON-ELSEVIER SCIENCE LTD, Lyon, FRANCE, pp. 95 - 95, presented at 20th Meeting of the European-Association-for-Cancer-Research, Lyon, FRANCE, 05 July 2008 - 08 July 2008, http://dx.doi.org/10.1016/S1359-6349(08)71542-8
2008
Valade D; Boyer CA; Bulmus V; Kavallaris M; Davis TP; Mccaroll J, 2008, 'Development of siRNA-Polymer Conjugates and Polyplexes', in Development of siRNA-Polymer Conjugates and Polyplexes, 30th Australasian Polymer Symposium, Melbourne, Australia, presented at 30th Australasian Polymer Symposium, Melbourne, Australia, 30 November 2008 - 04 December 2008
2008
Liaw TTYE; Burke PPA; Chen X; LaVallee TTM; Lock R; Kavallaris M, 2007, 'ENMD-1198 in combination with vincristine shows synergistic activity in leukemia cells and prolonged mouse survival in human leukemia xenografts', in BLOOD, AMER SOC HEMATOLOGY, Atlanta, GA, pp. 263A - 263A, presented at 49th Annual Meeting of the American-Society-of-Hematology, Atlanta, GA, 08 December 2007 - 11 December 2007, http://dx.doi.org/10.1182/blood.V110.11.859.859
2007
Liaw T; Burke P; Chen X; LaVallee T; Lock RB; Kavallaris M, 2007, 'ENMD-1198 in combination with vincristine shows synergistic activity in leukemia cells and prolonged mouse survival in human leukemia xenografts', in Broze G (ed.), Blood, American Society of Hematology, USA, pp. 859 - 859, presented at 49th Annual Meeting of the American-Society-of-Hematology, Atlanta, Georgia USA, 08 December 2007 - 11 December 2007
2007
Cheung BB; Bell J; Raif A; Yan J; Roediger B; Smith S; Lee M; Thomas WD; Kavallaris M; Norris M; Haber M; Liu H-L; Zajchowski D; Marshall GM, 2006, 'Characterization of a novel regulator of the retinoid signal: The estrogen-responsive B box protein.', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000454608804357&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2006
Schevzov G; Vrhovski B; Bryce NS; Elmir S; Qiu M; Yang N; Verrills NM; Kavallaris M; Puttur F; Hardeman E; Gunning P, 2004, 'Tropomyosin antibodies identify functionally distinct populations of actin filaments', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, Washington, DC, pp. 143A - 143A, presented at Annual Meeting of the American-Society-for-Cell-Biology, Washington, DC, 04 December 2004 - 08 December 2004, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000224648801136&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2004
Verrills N; Flemming C; Liu M; Ivery M; Norris MD; Haber M; Kavallaris M, 2002, 'Acquired beta-tubulin mutations affecting microtubule stability and drug binding', in MOLECULAR BIOLOGY OF THE CELL, AMER SOC CELL BIOLOGY, SAN FRANCISCO, CALIFORNIA, pp. 463A - 463A, presented at 42nd Annual Meeting of the American-Society-for-Cell-Biology, SAN FRANCISCO, CALIFORNIA, 14 December 2002 - 18 December 2002, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000179569102604&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
2002
Patents
add
Kavallaris M; Gan P, 2016, Methods for detecting and modulating the sensitivity of tumour cells to anti-mitotic agents, China, Patent No.
2016
Books
add
Kavallaris M, 2012, Cytoskeleton and human disease, http://dx.doi.org/10.1007/978-1-61779-788-0
2012

Fellowships

2017-2021                                 NHMRC Principal Research Fellowship

 

2014-2018                                 NHMRC Established Career Fellowship.  Highly competitive national award

 

2009 – 2013                              NHMRC Senior Research Fellowship.  Highly competitive national award

 

2004 – 2008                              NHMRC RD Wright Career Development Fellowship.  Highly competitive national award.

 

1996                                            International Agency for Research on Cancer, Cancer Research Training Fellowship*.  World Health Organisation.  Host: Prof. Susan B Horwitz, Department Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, New York, USA.  *Highly competitive fellowship with only 13 awarded worldwide in 1995.

 

Prizes/Awards

2020                                          NSW Premier's Woman of the Year 

2019                                          Lemberg Medal, ASBMB

2019                                          UTS Chancellor’s Excellence Award 

2019                                                     UTS Alumni Excellence Award for Science

2019                                           Member of the Order of Australia (AM)

2017                                           Premier's Science and Engineering Prize for Leadership in Innovation in NSW

2015                                           AFR/Westpac 100 Women of Influence

2015                                            “Knowledge Nation 100”  (Australia’s top 100 visionaries, intellects, founders and game changers who help shape the country’s future prosperity).

2015                                            The Australian Financial Review & Westpac “100 Women of Influence” Award

2013                                            NSInnovations People’s Choice Award and Division Finalist for the “Development of a first-in-class lung cancer therapeutic

2011                                            OEEGA International Women’s Day – Award for Excellence in the field of Scientific Research

2007                                            Australian Museum Eureka Prize for Voiceless Research Which Replaces the Use of Animals or Animal Products – “Unravelling the Enigma of Drug Resistance in Cancer” – M Kavallaris, S Pouha and Nicole Verrills.  $10,000 prize

2007 (Oct)                                 Visiting Professorship Awarded from the University of Marseille, France (all expenses paid)

2005                                            Achievement Award International Women’s Day – in recognition of “extraordinary contributions to research”, Cyprus Community of NSW

2004                                            Young Tall Poppy Award – recognises “achievements of outstanding young researchers in the sciences and biomedical sciences”, Australian Institute of Policy and Science

2002                                            Institute Award - Children’s Cancer Institute Australia for Outstanding Service in Pursuit of the Institute’s Vision

1998                                            Leo & Jenny Leukaemia and Cancer Foundation Your Research of the Year.  Finalist and Merit Certificate Awardee.

1998                                            Bristol Myers Squibb Oncology Young Investigator Award – American Association for Cancer Research Meeting, New Orleans, March, 1998.  Highly competitive award.

1997                                            B G Levanthal Scholar Award – Women in Cancer Research.  American Association for Cancer Research Meeting, San Diego, CA, April 1997.  Highly competitive award.

1996                                            Bristol Myers Squibb Oncology Travel Award – American Association for Cancer Research Meeting, Washington DC, April 1996.  Highly competitive.

1994                                            NSW State Cancer Council Travel Grant.  To attend the “New Horizons in Amplification Technology” conference in San Francisco, June 1994.  These awards were presented to promising young investigators to enable them to attend and present at international meetings.

1990                                            Tow Research Prize – Coast Medical Association Meeting, Prince Henry Hospital, NSW, Australia

Cancer, antimitotic drugs, drug resistance.