Luke Hesson

Adjunct Associate Professor

Publications

Journal articles
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Poulos RC; Perera D; Packham D; Shah A; Janitz C; Pimanda JE; Hawkins N; Ward RL; Hesson LB; Wong JWH, 2019, 'Scarcity of Recurrent Regulatory Driver Mutations in Colorectal Cancer Revealed by Targeted Deep Sequencing', JNCI CANCER SPECTRUM, vol. 3, http://dx.doi.org/10.1093/jncics/pkz012
2019
Unnikrishnan A; Vo ANQ; Pickford R; Raftery MJ; Nunez AC; Verma A; Hesson LB; Pimanda JE, 2018, 'AZA-MS: A novel multiparameter mass spectrometry method to determine the intracellular dynamics of azacitidine therapy in vivo', Leukemia, vol. 32, pp. 900 - 910, http://dx.doi.org/10.1038/leu.2017.340
2018
Morris MJ; Hesson LB; Poulos RC; Ward RL; Wong JWH; Youngson NA, 2018, 'Reduced nuclear DNA methylation and mitochondrial transcript changes in adenomas do not associate with mtDNA methylation', Biomarker Research, vol. 6, pp. 37, http://dx.doi.org/10.1186/s40364-018-0151-x
2018
Liu Q; Thoms JAI; Nunez AC; Huang Y; Knezevic K; Packham D; Poulos RC; Williams R; Beck D; Hawkins NJ; Ward RL; Wong JWH; Hesson LB; Sloane MA; Pimanda JE, 2018, 'Disruption of a 35 KB enhancer impairs CTCF binding and MLH1 expression in colorectal cells', Clinical Cancer Research, vol. 24, pp. 4602 - 4611, http://dx.doi.org/10.1158/1078-0432.CCR-17-3678
2018
Jacquelin S; Straube J; Cooper L; Vu T; Song A; Bywater M; Baxter E; Heidecker M; Wackrow B; Porter A; Ling V; Green J; Austin R; Kazakoff S; Waddell N; Hesson LB; Pimanda JE; Stegelmann F; Bullinger L; Döhner K; Rampal RK; Heckl D; Hill GR; Lane SW, 2018, 'Jak2V617F and Dnmt3a loss cooperate to induce myelofibrosis through activated enhancer-driven inflammation', Blood, vol. 132, pp. 2707 - 2721, http://dx.doi.org/10.1182/blood-2018-04-846220
2018
Ma SSQ; Henry CE; Llamosas E; Higgins R; Daniels B; Hesson LB; Hawkins NJ; Ward RL; Ford CE, 2017, 'Validation of specificity of antibodies for immunohistochemistry: the case of ROR2', Virchows Archiv : an international journal of pathology, vol. 470, pp. 99 - 108, http://dx.doi.org/10.1007/s00428-016-2019-5
2017
Unnikrishnan A; Quynh AVN; Pickford R; Nunez A; Hesson L; Pimanda J, 2017, 'A NOVEL MASS SPECTROMETRY METHOD REVEALS THE INTRACELLULAR PHARMACOKINETICS OF AZACYTIDINE THERAPY IN VIVO', in HAEMATOLOGICA, FERRATA STORTI FOUNDATION, Madrid, SPAIN, Vol. 102, pp. 258 - 259, presented at 22nd Congress of the European-Hematology-Association, Madrid, SPAIN, 22 June 2017 - 25 June 2017, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000404127002145&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2017
Luo A; Leach ST; Barres R; Hesson LB; Grimm MC; Simar D, 2017, 'The microbiota and epigenetic regulation of t helper 17/regulatory T cells: In search of a balanced immune system', Frontiers in Immunology, vol. 8, pp. 417, http://dx.doi.org/10.3389/fimmu.2017.00417
2017
Liu Q; Hesson LB; Nunez AC; Packham D; Williams R; Ward RL; Sloane MA, 2016, 'A cryptic paracentric inversion of MSH2 exons 2-6 causes Lynch syndrome', Carcinogenesis, vol. 37, pp. 10 - 17, http://dx.doi.org/10.1093/carcin/bgv154
2016
Liu Q; Hesson LB; Nunez AC; Packham D; Hawkins NJ; Ward RL; Sloane MA, 2016, 'Pathogenic germline MCM9 variants are rare in Australian Lynch-like syndrome patients', Cancer Genetics, vol. 209, pp. 497 - 500, http://dx.doi.org/10.1016/j.cancergen.2016.10.001
2016
Thoms JAI; Knezevic K; Liu JJ; Glaros EN; Thai T; Qiao Q; Campbell H; Packham D; Huang Y; Papathanasiou P; Tunningley R; Whittle B; Yeung AWS; Chandrakanthan V; Hesson L; Chen V; Wong JWH; Purton LE; Ward RL; Thomas SR; Pimanda JE, 2016, 'Arrested hematopoiesis and vascular relaxation defects in mice with a mutation in Dhfr', Molecular and Cellular Biology, vol. 36, pp. 1222 - 1236, http://dx.doi.org/10.1128/MCB.01035-15
2016
Youngson N; Lecomte V; Maloney C; Leung P; Liu J; Hesson L; Luciani F; Krause L; Morris M, 2016, 'Obesity-induced sperm DNA methylation changes at satellite repeats are reprogrammed in rat offspring', Asian Journal of Andrology, vol. 18, pp. 930 - 936, http://dx.doi.org/10.4103/1008-682X.163190
2016
Kuroiwa-Trzmielina J; Hesson LB, 2016, 'Epigenetic Effects of Gut Microbiota on Obesity and Gastrointestinal Cancers', in Berger NA (ed.), EPIGENETICS, ENERGY BALANCE, AND CANCER, edn. Energy Balance and Cancer, SPRINGER INTERNATIONAL PUBLISHING AG, pp. 167 - 189, http://dx.doi.org/10.1007/978-3-319-41610-6_7
2016
Chandrakanthan V; Yeola A; Kwan JC; Oliver RA; Qiao Q; Kang YC; Zarzour P; Beck D; Boelen L; Unnikrishnan A; Villanueva JE; Nunez AC; Knezevic K; Palu C; Nasrallah R; Carnell M; Macmillan A; Whan R; Yu Y; Hardy P; Grey ST; Gladbach A; Delerue F; Ittner L; Mobbs R; Walkley CR; Purton LE; Ward RL; Wong JWH; Hesson LB; Walsh W; Pimanda JE, 2016, 'Pdgf-ab and 5-Azacytidine induce conversion of somatic cells into tissue-regenerative multipotent stem cells', Proceedings of the National Academy of Sciences of the United States of America, vol. 113, pp. E2306 - E2315, http://dx.doi.org/10.1073/pnas.1518244113
2016
Chandrakanthan V; Yeola A; Kwan JC; Oliver RA; Qiao Q; Kang YC; Zarzour P; Beck D; Boelen L; Unnikrishnan A; Villanueva JE; Nunez AC; Knezevic K; Palu C; Nasrallah R; Carnell M; Macmillan A; Whan R; Yu Y; Hardy P; Grey ST; Gladbach A; Delerue F; Ittner L; Mobbs R; Walkley CR; Purton LE; Ward RL; Wong JWH; Hesson LB; Walsh W; Pimanda JE, 2016, 'PDGF-AB and 5-Azacytidine induce conversion of somatic cells into tissue-regenerative multipotent stem cells', in PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, NATL ACAD SCIENCES, Vol. 113, pp. E2306 - E2315, http://dx.doi.org/10.1073/pnas.1518244113
2016
Liu Q; Thompson BA; Ward RL; Hesson LB; Sloane MA, 2016, 'Understanding the Pathogenicity of Noncoding Mismatch Repair Gene Promoter Variants in Lynch Syndrome', Human Mutation, vol. 37, pp. 417 - 426, http://dx.doi.org/10.1002/humu.22971
2016
Ma S; srivastava S; llamosas E; hawkins N; hesson L; ward R; Ford C, 2016, 'ROR2 is epigenetically inactivated in the early stages of colorectal neoplasia and is associated with proliferation and migration.', BMC Cancer, vol. 16, http://dx.doi.org/10.1186/s12885-016-2576-7
2016
Sloane MA; Ward RL; Hesson LB, 2016, 'Defining the criteria for identifying constitutional epimutations', Clinical Epigenetics, vol. 8, http://dx.doi.org/10.1186/s13148-016-0207-4
2016
Ma SSQ; Henry CE; Llamosas E; Higgins R; Daniels B; Hesson LB; Hawkins NJ; Ward RL; Ford CE, 2016, 'Erratum to: Validation of specificity of antibodies for immunohistochemistry: the case of ROR2 (Virchows Archiv, (2016), 10.1007/s00428-016-2019-5)', Virchows Archiv, vol. 469, pp. 717, http://dx.doi.org/10.1007/s00428-016-2036-4
2016
Srivastava S; Ludwig AK; Wong JWH; Hesson LB, 2016, 'An investigation of the potential for epigenetic inactivation by transcription read-through in a sporadic colorectal cancer', Gene, vol. 585, pp. 154 - 158, http://dx.doi.org/10.1016/j.gene.2016.03.031
2016
Hesson LB; Ng B; Zarzour P; Srivastava S; Kwok CT; Packham D; Nunez AC; Beck D; Ryan R; Dower A; Ford CE; Pimanda JE; Sloane MA; Hawkins NJ; Bourke MJ; Wong JWH; Ward RL, 2016, 'Integrated genetic, epigenetic, and transcriptional profiling identifies molecular pathways in the development of laterally spreading tumors', Molecular Cancer Research, vol. 14, pp. 1217 - 1228, http://dx.doi.org/10.1158/1541-7786.MCR-16-0175
2016
Hesson LB; Packham D; Kwok CT; Nunez AC; Ng B; Schmidt C; Fields M; Wong JW; Sloane MA; Ward RL, 2015, 'Lynch Syndrome associated with two MLH1 promoter variants and allelic imbalance of MLH1 expression.', Human Mutation, vol. 36, pp. 622 - 630, http://dx.doi.org/10.1002/humu.22785
2015
Sloane M; Liu Q; Nunez A; Packham D; Kwok C-T; Suthers G; Du Sart D; Williams R; Hesson L; Ward R, 2015, 'TRANSLATING BASIC RESEARCH INTO THE CLINICAL MANAGEMENT OF FAMILIES WITH LYNCH SYNDROME', in Asia-Pacific Journal of Clinical Oncology, WILEY-BLACKWELL, Vol. 11, pp. 102 - 102, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000364320800126&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2015
Zarzour P; Boelen L; Luciani F; Beck D; Sakthianandeswaren A; Mouradov D; Sieber OM; Hawkins NJ; Hesson LB; Ward RL; Wong JWH, 2015, 'Single nucleotide polymorphism array profiling identifies distinct chromosomal aberration patterns across colorectal adenomas and carcinomas', Genes Chromosomes and Cancer, vol. 54, pp. 303 - 314, http://dx.doi.org/10.1002/gcc.22243
2015
Sloane MA; Nunez AC; Packham D; Kwok CT; Suthers G; Hesson LB; Ward RL, 2015, 'Mosaic epigenetic inheritance as a cause of early-onset colorectal cancer', JAMA Oncology, vol. 1, pp. 953 - 957, http://dx.doi.org/10.1001/jamaoncol.2015.1484
2015
Poulos RC; Sloane MA; Hesson LB; Wong JWH, 2015, 'The search for cis-regulatory driver mutations in cancer genomes', Oncotarget, vol. 6, pp. 32509 - 32525, http://dx.doi.org/10.18632/oncotarget.5085
2015
Hesson LB; Ward RL, 2014, 'Discrimination of pseudogene and parental gene dna methylation using allelic bisulfite sequencing', Methods in Molecular Biology, vol. 1167, pp. 265 - 274, http://dx.doi.org/10.1007/978-1-4939-0835-6_18
2014
Sloane MA; Hesson LB; Ward RL, 2014, 'Epimutations and cancer susceptibility', eLS, vol. Published Online: 17 MAR 2014, pp. 1 - 10, http://dx.doi.org/10.1002/9780470015902.a0024615
2014
Simar D; Versteyhe S; Donkin I; Liu J; Hesson L; Nylander V; Fossum A; Barres R, 2014, 'DNA Methylation Is Altered In B And NK Lymphocytes In Obese And Type 2 Diabetic Human', Metabolism: clinical and experimental, vol. 63, pp. 1188 - 1197, http://dx.doi.org/10.1016/j.metabol.2014.05.014
2014
Hesson LB; Ward RL, 2014, 'The importance of distinguishing pseudogenes from parental genes', Clinical Epigenetics, vol. 6, pp. 90, http://dx.doi.org/10.1186/s13148-014-0033-5
2014
Sloane MA; Wong JWH; Perera D; Nunez AC; Pimanda JE; Hawkins NJ; Sieber OM; Bourke MJ; Hesson LB; Ward RL, 2014, 'Epigenetic inactivation of the candidate tumor suppressor USP44 is a frequent and early event in colorectal neoplasia', Epigenetics, vol. 9, pp. 1092 - 1100, http://dx.doi.org/10.4161/epi.29222
2014
Hesson LB; Sloane MA; Wong JWH; Nunez AC; Srivastava S; Ng B; Hawkins NJ; Bourke MJ; Ward RL, 2014, 'Altered promoter nucleosome positioning is an early event in gene silencing', Epigenetics, vol. 9, pp. 1422 - 1430, http://dx.doi.org/10.4161/15592294.2014.970077
2014
Patil V; Ward RL; Hesson LB, 2014, 'The evidence for functional non-CpG methylation in mammalian cells', Epigenetics, vol. 9, pp. 823 - 828, http://dx.doi.org/10.4161/epi.28741
2014
Sloane MA; Hesson LB; Nunez AC; Thompson BA; Ward RL, 2014, 'Nucleosome positioning is unaltered at MLH1 splice site mutations in cells derived from Lynch syndrome patients', Clinical Epigenetics, vol. 6, http://dx.doi.org/10.1186/s13148-014-0032-6
2014
Hesson LB; Patil V; Sloane MA; Nunez AC; Liu J; Pimanda JE; Ward RL, 2013, 'Reassembly of Nucleosomes at the MLH1 Promoter Initiates Resilencing Following Decitabine Exposure', PLoS Genetics, vol. 9, http://dx.doi.org/10.1371/journal.pgen.1003636
2013
Hesson L, 2013, 'Gut microbiota and obesity-related gastrointestinal cancer: a focus on epigenetics', Translational Gastrointestinal Cancer, vol. 2, pp. 204 - 210
2013
Liu J; Hesson LB; Ward RL, 2013, 'Liquid chromatography tandem mass spectrometry for the measurement of global DNA methylation and hydroxymethylation', Journal of Proteomics & Bioinformatics, vol. 01, http://dx.doi.org/10.4172/jpb.S2-005
2013
Metz AJ; Bourke MJ; Moss A; Dower A; Zarzour P; Hawkins NJ; Ward RL; Hesson L, 2013, 'A correlation of the endoscopic characteristics of colonic laterally spreading tumours (LSTs) with genetic alterations', European Journal of Gastroenterology and Hepatology, vol. 25, pp. 319 - 326, http://dx.doi.org/10.1097/MEG.0b013e32835b57e7
2013
Zarzour P; Hesson LB; Ward RL, 2013, 'Establishing the clinical utility of epigenetic markers in cancer: Many challenges ahead', Epigenomics, vol. 5, pp. 513 - 523, http://dx.doi.org/10.2217/epi.13.53
2013
Liu J; Hesson LB; Meagher AP; Bourke MJ; Hawkins NJ; Rand KN; Molloy PL; Pimanda JE; Ward RL, 2012, 'Relative distribution of folate species is associated with global DNA methylation in human colorectal mucosa', in CANCER RESEARCH, AMER ASSOC CANCER RESEARCH, Vol. 72, http://dx.doi.org/10.1158/1538-7445.AM2012-3125
2012
Hesson LB; Wong JWH; Sloane MA; Pimanda JE; Bourke MJ; Hawkins NJ; Ward RL, 2012, 'Nucleosome occupancy at unmethylated promoter CpG islands represents a novel mechanism of epigenetic gene silencing in cancer', CANCER RESEARCH, vol. 72, http://dx.doi.org/10.1158/1538-7445.AM2012-990
2012
Hesson L; Packham D; Pontzer E; Funchain P; Eng C; Ward RL, 2012, 'A reinvestigation of somatic hypermethylation at the PTEN CpG island in cancer cell lines', Biological Procedures Online, vol. 14, pp. 1 - 8, http://dx.doi.org/10.1186/1480-9222-14-5
2012
Lau DT; Hesson L; Norris MD; Marshall GM; Haber M; Ashton LJ, 2012, 'Prognostic Significance of Promoter DNA Methylation in Patients with Childhood Neuroblastoma', Clinical Cancer Research, vol. 18, pp. 5690 - 5700, http://dx.doi.org/10.1158/1078-0432.CCR-12-0294
2012
Liu J; Hesson L; Meagher AP; Bourke MJ; Hawkins NJ; Rand KN; Molloy PL; Pimanda JE; Ward RL, 2012, 'Relative distribution of folate species is associated with global DNA methylation in human colorectal mucosa', CANCER PREVENTION RESEARCH, vol. 5, pp. 921 - 929, http://dx.doi.org/10.1158/1940-6207.CAPR-11-0577
2012
Metz AJ; Bourke MJ; Moss A; Hesson L; Ward R, 2011, 'A Correlation of the Endoscopic Characteristics of Colonic Laterally Spreading Tumours (LSTS) With Genetic Mutations', in GASTROENTEROLOGY, W B SAUNDERS CO-ELSEVIER INC, Chicago, IL, pp. S191 - S191, presented at Conference on Digestive Disease Week 2011, Chicago, IL, 07 May 2011 - 10 May 2011, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000290167300770&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2011
Liu JJ; Hesson LB; Rand KN; Molloy PL; Pimanda J; Ward RL, 2011, 'Analysis of global and repeat sequence DNA methylation in the blood and normal colonic mucosa of colorectal cancer patients, healthy individuals and patients with folate deficiency', CANCER RESEARCH, vol. 71, http://dx.doi.org/10.1158/1538-7445.AM2011-91
2011
Hesson LB; Patil V; Sloane M; Ward RL, 2011, 'Investigation of the molecular events associated with gene resilencing following withdrawal of epigenetic therapies', CANCER RESEARCH, vol. 71, http://dx.doi.org/10.1158/1538-7445.AM2011-2000
2011
Lock FE; Underhill-Day N; Dunwell TL; Matallanas D; Cooper W; Hesson L; Recino A; Ward A; Pavlova TV; Zabarovsky ER; Grant M; Maher ER; Chalmers AD; Kolch W; Latif F, 2010, 'The RASSF8 candidate tumor suppressor inhibits cell growth and regulates the Wnt and NF-kB signaling pathways', Oncogene, vol. 29, pp. 4307 - 4316
2010
Hesson L; Donninger H; Latif F; Vos MD; Beebe K; Gordon L; Sidransky D; Liu JW; Schlegel T; Payne S; Hartmann A, 2010, 'The Ras effector RASSF2 controls the PAR-4 tumor suppressor.', Molecular and Cellular Biology, vol. 30, pp. 2608 - 2620
2010
Dunwell TL; Hesson L; Rauch TA; Wang L; Clark R; Dallol A; Gentle D; Catchpoole DR; Maher ER; Pfeifer G; Latif F, 2010, 'A Genome-wide screen identifies frequently methylated genes in haematological and epithelial cancers', Molecular Cancer, vol. 9, pp. 44 - 44
2010
Metz AJ; Bourke MJ; Moss A; Hesson L; Ward R, 2010, 'A correlation of the endoscopic characteristics of colonic laterally spreading tumours (LSTs) with genetic mutations', Vol. 25, pp. A78 - A78, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000283321200212&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2010
Hesson L; Hitchins MP; Ward RL, 2010, 'Epimutations and cancer predisposition: importance and mechanisms', Current Opinion in Genetics and Development, vol. 20, pp. 1 - 9, http://dx.doi.org/10.1016/j.gde.2010.02.005
2010
Hill VK; Hesson L; Dansranjavin T; Dallol A; Bieche I; Vacher S; Tommasi S; Dobbins TA; Gentle D; Euhus D; Dammann R; Ward RL; Minna JD; Maher ER; Pfeifer G; Latif F, 2010, 'Identification of 5 novel genes methylated in breast and other epithelial cancers', Molecular Cancer Research, vol. 9, pp. 51 - 66, http://dx.doi.org/10.1186/1476-4598-9-51
2010
Cooper W; Hesson L; Matallanas D; Dallol A; Von Kriegsheim A; Ward RL; Kolch W; Latif F, 2009, 'RASSF2 associates with and stabilizes the proapoptotic kinase MST2', Oncogene, vol. 28, pp. 2988 - 2998, http://dx.doi.org/10.1038/onc.2009.152
2009
Dunwell TL; Hesson L; Pavlova TV; Zabarovska V; Kashuba V; Catchpoole DR; Chiaramonte R; Brini AT; Griffiths M; Maher ER; Zabarovsky ER; Latif F, 2009, 'Epigenetic analysis of childhood acute lymphoblastic leukemia', Epigenetic analysis of childhood acute lymphoblastic leukemia, vol. 4, pp. 185 - 193
2009
Hesson L; Dunwell TL; Cooper WN; Catchpoole DR; Brini AT; Chiaramonte R; Chalmers AD; Griffiths M; Maher ER; Latif F, 2009, 'The novel RASSF6 and RASSF10 candidate tumour suppressor genes are frequently epigenetically inactivated in childhood leukaemias', Molecular Cancer, vol. 8, pp. 42 - 42
2009
Dallol A; Hesson L; Matallanas D; Cooper WN; O''neill E; Maher ER; Kolch W; Latif F, 2009, 'Ran GTPase is a RASSF1A effector involved in controlling microtubule organisation', Ran GTPase is a RASSF1A effector involved in controlling microtubule organisation, vol. 19, pp. 1227 - 1232
2009
Morton S; Hesson L; Peggie M; Cohen P, 2008, 'Enhanced binding of TBK1 by an optineurin mutant that causes a familial form of primary open angle glaucoma.', FEBS Letters, vol. 582, pp. 997 - 1002
2008
Hesson L; Krex D; Latif F, 2008, 'Epigenetic markers of human gliomas – prospects for therapeutic intervention', Expert Review of Neurotherapeutics, vol. 8, pp. 1475 - 1496
2008
Allen NPC; Donninger H; Vos MD; Eckfeld K; Hesson L; Gordon L; Birrer MJ; Latif F; Clark GJ, 2007, 'RASSF6 is a novel member of the RASSF family of tumor suppressors.', Oncogene, vol. 26, pp. 6203 - 6211
2007
Hesson L; Cooper WN; Latif F, 2007, 'Evaluation of the 3p21.3 Tumour-suppressor Gene Cluster', Oncogene, vol. 26, pp. 7283 - 7301
2007
Hesson L; Cooper WN; Latif F, 2007, 'The role of RASSF1A methylation in cancer', Disease Markers, vol. 23, pp. 73 - 87
2007
Cooper WN; Dickinson RE; Dallol A; Grigorieva EV; Pavlova TV; Hesson L; Bieche I; Broggini M; Maher ER; Zabarovsky ER; Clark GJ; Latif F, 2007, 'Epigenetic regulation of the ras effector/tumour suppressor RASSF2 in breast and lung cancer', Oncogene, vol. 27, pp. 1805 - 1811
2007
Vos MD; Dallol A; Eckfeld K; Allen NPC; Donninger H; Hesson L; Calvisi D; Latif F; Clark GJ, 2006, 'The RASSF1A tumor suppressor activates Bax via MOAP-1', The Journal of Biological Chemistry, vol. 281, pp. 4557 - 4563
2006
Hesson L; Wilson R; Morton D; Walker M; Maher ER; Latif F, 2005, 'CpG island promoter hypermethylation of a novel Ras-effector gene RASSF2A is an early event in colon carcinogenesis and correlates inversely with K-ras mutations', Oncogene, vol. 24, pp. 3987 - 3994
2005
Elam C; Hesson L; Vos MD; Eckfeld K; Ellis CA; Bell A; Krex D; Birrer MJ; Latif F; Clark GJ, 2005, 'RRP22 is a farnesylated, nucleolar, Ras-related protein with tumor suppressor potential', Cancer research, vol. 65, pp. 3117 - 3125
2005
Caren H; Ejeskar K; Fransson S; Hesson L; Latif F; Sjoberg RM; Krona C; Martinsson T, 2005, 'A cluster of genes located in 1p36 are down-regulated in neuroblastomas with poor prognosis, but not due to CpG island methylation', Molecular Cancer, vol. 4, pp. 10
2005
Hesson L; Bieche I; Krex D; Criniere E; Hoang-xuan K; Maher ER; Latif F, 2004, 'Frequent epigenetic inactivation of RASSF1A and BLU genes located within the critical 3p21.3 region in gliomas', Oncogene, vol. 23, pp. 2408 - 2419
2004
Fenton SL; Dallol A; Agathanggelou A; Hesson L; Ahmed-choudhury J; Baksh S; Sardet C; Dammann R; Minna JD; Downward J; Maher ER; Latif F, 2004, 'Identification of the E1A-regulated transcription factor p120 E4F as an interacting partner of the RASSF1A candidate tumor suppressor gene', Cancer research, vol. 64, pp. 102 - 107
2004
Eckfeld K; Hesson L; Vos MD; Bieche I; Latif F; Clark GJ, 2004, 'RASSF4/AD037 is a potential ras effector/tumor suppressor of the RASSF family', Cancer research, vol. 64, pp. 8688 - 8693
2004
Dallol A; Agathanggelou A; Fenton SL; Hesson L; Ahmed-choudhury J; Vos MD; Clark GJ; Downward J; Maher ER; Latif F, 2004, 'RASSF1A interacts with microtubule-associated proteins and modulates microtubule dynamics', Cancer research, vol. 64, pp. 4112 - 4116
2004
Morris MR; Hesson L; Wagner KJ; Morgan NV; Astuti D; Lees RD; Cooper WN; Lee J; Gentle D; Macdonald F; Kishida T; Grundy R; Yao M; Latif F; Maher ER, 2003, 'Multigene methylation analysis of Wilms' tumour and adult renal cell carcinoma', Oncogene, vol. 22, pp. 6794 - 6801
2003
Dallol A; Krex D; Hesson L; Eng C; Maher ER; Latif F, 2003, 'Frequent epigenetic inactivation of the SLIT2 gene in gliomas', Oncogene, vol. 22, pp. 4611 - 4616
2003
Hesson L; Dallol A; Minna JD; Maher ER; Latif F, 2003, 'NORE1A, a homologue of RASSF1A tumour suppressor gene is inactivated in human cancers', Oncogene, vol. 22, pp. 947 - 954
2003
Da silva NF; Gentle D; Hesson L; Morton D; Latif F; Maher ER, 2003, 'Analysis of the Birt-Hogg-Dube (BHD) tumour suppressor gene in sporadic renal cell carcinoma and colorectal cancer', Journal of Medical Genetics, vol. 40, pp. 820 - 824
2003
Agathanggelou A; Dallol A; Zochbauer-muller S; Morrissey C; Honorio S; Hesson L; Martinsson T; Fong KM; Kuo MJ; Yuen PW; Maher ER; Minna JD; Latif F, 2003, 'Epigenetic inactivation of the candidate 3p21.3 suppressor gene BLU in human cancers', Oncogene, vol. 22, pp. 1580 - 1588
2003