John Power

Senior Lecturer

Dr. John Power is a Senior Lecturer within the Department of Physiology and the Neuroscience Honours Coordinator.  He leads Neuroplasticity in Memory and Addiction Group within the Translational Neuroscience Facility.  Dr. Power is an expert in the cellular basis of memory formation.  His previous research has contributed to our understanding of the biophysical changes that underlie aging and associative learning, the role of the endoplasmic reticulum in neuronal calcium signalling, and amygdala neurophysiology.   His group continues to investigate the cellular mechanisms of memory formation using a combination of electrophysiological recordings, live-cell fluorescent calcium imaging and genetic manipulations.  The current focus of his research is the identification of novel cellular mechanisms that modulate or preserve neuronal connections that may be translated into treatments for disorders of impaired or aberrant connectivity such as Alzheimer’s disease, stroke, post-traumatic stress disorder, epilepsy and addiction. 

Student projects can be found here.

publications

Journal articles
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Bolaram A; Coe TE; Power JM; Cheng DT, 2020, 'Awareness and differential eyeblink conditioning: effects of manipulating auditory CS frequencies', Learning & memory (Cold Spring Harbor, N.Y.), vol. 27, pp. 78 - 82, http://dx.doi.org/10.1101/lm.050146.119
2020
Prasad AA; Xie C; Chaichim C; Nguyen JH; McClusky HE; Killcross S; Power JM; McNally GP, 2020, 'Complementary roles for ventral pallidum cell types and their projections in relapse', Journal of Neuroscience, vol. 40, pp. 880 - 893, http://dx.doi.org/10.1523/JNEUROSCI.0262-19.2019
2020
Moorhouse AJ; Power JM, 2019, 'Making light work of fine-tuning channelrhodopsins', Journal of Biological Chemistry, vol. 294, pp. 3822 - 3823, http://dx.doi.org/10.1074/jbc.H119.007749
2019
Sengupta A; Yau JOY; Jean-Richard-dit-Bressel P; Liu Y; Millan EZ; Power JM; McNally GP, 2018, 'Basolateral amygdala neurons maintain aversive emotional salience', Journal of Neuroscience, vol. 38, pp. 3001 - 3012, http://dx.doi.org/10.1523/JNEUROSCI.2460-17.2017
2018
Gibson GD; Prasad AA; Jean-Richard-dit-Bressel P; Yau JOY; Millan EZ; Liu Y; Campbell EJ; Lim J; Marchant NJ; Power JM; Killcross S; Lawrence AJ; McNally GP, 2018, 'Distinct Accumbens Shell Output Pathways Promote versus Prevent Relapse to Alcohol Seeking', Neuron, vol. 98, pp. 512 - 520.e6, http://dx.doi.org/10.1016/j.neuron.2018.03.033
2018
Gorlamandala N; Parmar J; Craig AJ; Power JM; Moorhouse AJ; Krishnan AV; Housley GD, 2018, 'Focal Ischaemic Infarcts Expand Faster in Cerebellar Cortex than Cerebral Cortex in a Mouse Photothrombotic Stroke Model', Translational Stroke Research, vol. 9, pp. 643 - 653, http://dx.doi.org/10.1007/s12975-018-0615-1
2018
Jhaveri DJ; Tedoldi A; Hunt S; Sullivan R; Watts NR; Power JM; Bartlett PF; Sah P, 2018, 'Evidence for newly generated interneurons in the basolateral amygdala of adult mice', Molecular Psychiatry, vol. 23, pp. 521 - 532, http://dx.doi.org/10.1038/mp.2017.134
2018
Weiss C; Procissi D; Power JM; Disterhoft JF, 2018, 'The rabbit as a behavioral model system for magnetic resonance imaging', Journal of Neuroscience Methods, vol. 300, pp. 196 - 205, http://dx.doi.org/10.1016/j.jneumeth.2017.05.021
2018
Suchowerska AK; Fok S; Stefen H; Gunning PW; Hardeman EC; Power J; Fath T, 2017, 'Developmental profiling of tropomyosin expression in mouse brain reveals Tpm4.2 as the major post-synaptic tropomyosin in the mature brain', Frontiers in Cellular Neuroscience, vol. 11, http://dx.doi.org/10.3389/fncel.2017.00421
2017
Stefen H; Chaichim C; Power J; Fath T, 2016, 'Regulation of the Postsynaptic Compartment of Excitatory Synapses by the Actin Cytoskeleton in Health and Its Disruption in Disease', Neural Plasticity, vol. 2016, http://dx.doi.org/10.1155/2016/2371970
2016
Yang JL; Polly P; Fath T; Jones N; Power J, 2016, 'ISA model and integrative career development learning in year three science courses', International Journal of Science, Mathematics and Technology Learning, vol. 23, pp. 33 - 49
2016
Keshavarzi S; Power JM; Albers EHH; Sullivan RKS; Sah P, 2015, 'Dendritic Organization of Olfactory Inputs to Medial Amygdala Neurons', The Journal of Neuroscience, vol. 35, pp. 13020 - 13028, http://dx.doi.org/10.1523/JNEUROSCI.0627-15.2015
2015
Keshavarzi S; Power JM; Albers EHH; Sullivan RKS; Sah P, 2015, 'Dendritic organization of olfactory inputs to medial amygdala neurons', Journal of Neuroscience, vol. 35, pp. 13020 - 13028, http://dx.doi.org/10.1523/JNEUROSCI.0627-15.2015
2015
Harasta AE; Power JM; Von Jonquieres G; Karl T; Drucker DJ; Housley GD; Schneider M; Klugmann M, 2015, 'Septal glucagon-like peptide 1 receptor expression determines suppression of cocaine-induced behavior', Neuropsychopharmacology, vol. 40, pp. 1969 - 1978, http://dx.doi.org/10.1038/npp.2015.47
2015
Power JM; Sah P, 2014, 'Dendritic spine heterogeneity and calcium dynamics in basolateral amygdala principal neurons', Journal of Neurophysiology, vol. 112, pp. 1616 - 1627, http://dx.doi.org/10.1152/jn.00770.2013
2014
Delaney A; Sedlak PL; Autuori E; Power J; Sah P, 2013, 'Synaptic NMDA receptors in basolateral amygdala principal neurons are triheteromeric proteins: physiological role of GluN2B subunits', Journal of Neurophysiology, vol. 109, pp. 1391 - 1402, http://dx.doi.org/10.1152/jn.00176.2012
2013
Cheng D; Meintjes EM; Stanton ME; Desmond J; Pienaar M; Dodge N; Power J; Molteno CD; Disterhoft JF; Jacobson JL; Jacobson SW, 2013, 'Functional MRI of cerebellar activity during eyeblink classical conditioning in children and adults.', Human Brain Mapping, vol. 35, pp. 1 - 14, http://dx.doi.org/10.1002/hbm.22261
2013
Delaney A; Power J; Pankaj S, 2012, 'Ifenprodil reduces excitatory synaptic transmission by blocking presynaptic P/Q type calcium channels', Journal of Neurophysiology, vol. 107, pp. 1571 - 1575, http://dx.doi.org/10.1152/jn.01066.2011
2012
Kim YS; Wong AC; Power J; Tadros SF; Klugmann M; Moorhouse AJ; Bertrand PP; Housley GD, 2012, 'Alternative Splicing of the TRPC3 Ion Channel Calmodulin/ IP3 Receptor-Binding Domain in the Hindbrain Enhances Cation Flux', The Journal of Neuroscience, vol. 32, pp. 11414 - 11423, http://dx.doi.org/10.1523/JNEUROSCI.6446-11.2012
2012
Power J; Bocklisch C; Curby P; Pankaj S, 2011, 'Location and function of the slow afterhyperpolarization channels in the basolateral amygdala', The Journal of Neuroscience, vol. 31, pp. 526 - 537, http://dx.doi.org/10.1523/JNEUROSCI.1045-10.2011
2011
Oh MM; McKay BM; Power J; Disterhoft JF, 2009, 'Learning-related postburst afterhyperpolarization reduction in CA1 pyramidal neurons is mediated by protein kinase A', Proceedings of the National Academy of Sciences, vol. 106, pp. 1620 - 1625, http://dx.doi.org/10.1073/pnas.0807708106
2009
Faber EL; Delaney A; Power J; Sedlak PL; Crane JW; Pankaj S, 2008, 'Modulation of SK channel trafficking by beta adrenoceptors enhances excitatory synaptic transmission and plasticity in the amygdala', The Journal of Neuroscience, vol. 29, pp. 10803 - 10813, http://dx.doi.org/10.1523/JNEUROSCI.1796-08.2008
2008
Power J; Pankaj S, 2008, 'Competition between calcium-activated K+ channels determines cholinergic action on firing properties of basolateral amygdala projection neurons', The Journal of Neuroscience, vol. 28, pp. 3209 - 3220, http://dx.doi.org/10.1523/JNEUROSCI.4310-07.2008
2008
Cheng D; Disterhoft JF; Power J; Ellis DA; Desmond J, 2008, 'Neural substrates underlying human delay and trace eyeblink conditioning', Proceedings of the National Academy of Sciences, vol. 105, pp. 8108 - 8113, http://dx.doi.org/10.1073/pnas.0800374105
2008
Power J; Pankaj S, 2007, 'Distribution of IP3-mediated calcium responses and their role in nuclear signalling in rat basolateral amygdala neurons', The Journal of Physiology, vol. 580, pp. 835 - 857, http://dx.doi.org/10.1113/jphysiol.2006.125062
2007
Morley SN; Power JM; Coulson EJ; Bartlett PF, 2007, 'Zinc-mediated neuronal death is dependent on Trk activation', Experimental Neurology, vol. 205, pp. 360 - 366, http://dx.doi.org/10.1016/j.expneurol.2007.02.006
2007
Oh MM; Wu WW; Power JM; Disterhoft JF, 2006, 'Galantamine increases excitability of CA1 hippocampal pyramidal neurons', Neuroscience, vol. 137, pp. 113 - 123, http://dx.doi.org/10.1016/j.neuroscience.2005.08.063
2006
Power JM; Sah P, 2005, 'Intracellular calcium store filling by an L-type calcium current in the basolateral amygdala at subthreshold membrane potentials', Journal of Physiology, vol. 562, pp. 439 - 453, http://dx.doi.org/10.1113/jphysiol.2004.076711
2005
Baharvand H; Power JM; Ozsarac N; Matthaei KI, 2004, 'Differentiation of embryonic stem cells into functional neurons in vitro', Neuroscience Research Communications, vol. 35, pp. 130 - 138, http://dx.doi.org/10.1002/nrc.20027
2004
Sah P; Faber ESL; De Armentia ML; Power J, 2003, 'The amygdaloid complex: Anatomy and physiology', Physiological Reviews, vol. 83, pp. 803 - 834, http://dx.doi.org/10.1152/physrev.00002.2003
2003
Power JM; Wu WW; Sametsky E; Oh MM; Disterhoft JF, 2002, 'Age-related enhancement of the slow outward calcium-activated potassium current in hippocampal CA1 pyramidal neurons in vitro', Journal of Neuroscience, vol. 22, pp. 7234 - 7243
2002
Knuttinen MG; Parrish TB; Weiss C; LaBar KS; Gitelman DR; Power JM; Mesulam MM; Disterhoft JF, 2002, 'Electromyography as a recording system for eyeblink conditioning with functional magnetic resonance imaging', NeuroImage, vol. 17, pp. 977 - 987, http://dx.doi.org/10.1016/S1053-8119(02)91199-7
2002
Knuttinen M-G; Parrish TB; Weiss C; LaBar KS; Gitelman DR; Power JM; Mesulam M-M; Disterhoft JF, 2002, 'Electromyography as a Recording System for Eyeblink Conditioning with Functional Magnetic Resonance Imaging', NeuroImage, vol. 17, pp. 977 - 987, http://dx.doi.org/10.1006/nimg.2002.1199
2002
Power JM; Sah P, 2002, 'Nuclear Calcium Signaling Evoked by Cholinergic Stimulation in Hippocampal CA1 Pyramidal Neurons', Journal of Neuroscience, vol. 22, pp. 3454 - 3462
2002
Weiss C; Venkatasubramanian PN; Aguado AS; Power JM; Tom BC; Li L; Chen KS; Disterhoft JF; Wyrwicz AM, 2002, 'Impaired eyeblink conditioning and decreased hippocampal volume in PDAPP V717F mice', Neurobiology of Disease, vol. 11, pp. 425 - 433, http://dx.doi.org/10.1006/nbdi.2002.0555
2002
Knuttinen MG; Gamelli AE; Weiss C; Power JM; Disterhoft JF, 2001, 'Age-related effects on eyeblink conditioning in the F344 × BN F1 hybrid rat', Neurobiology of Aging, vol. 22, pp. 1 - 8, http://dx.doi.org/10.1016/S0197-4580(00)00194-9
2001
Geinisman Y; Berry RW; Disterhoft JF; Power JM; Van Der Zee EA, 2001, 'Associative learning elicits the formation of multiple-synapse boutons', Journal of Neuroscience, vol. 21, pp. 5568 - 5573
2001
Knuttinen MG; Power JM; Preston AR; Disterhoft JF, 2001, 'Awareness in classical differential eyeblink conditioning in young and aging humans', Behavioral Neuroscience, vol. 115, pp. 747 - 757, http://dx.doi.org/10.1037/0735-7044.115.4.747
2001
Power JM; Oh MM; Disterhoft JF, 2001, 'Metrifonate decreases sIAHP in CA1 pyramidal neurons in vitro', Journal of Neurophysiology, vol. 85, pp. 319 - 322
2001
Moyer JR; Power JM; Thompson LT; Disterhoft JF, 2000, 'Increased excitability of aged rabbit CA1 neurons after trace eyeblink conditioning', Journal of Neuroscience, vol. 20, pp. 5476 - 5482
2000
Geinisman Y; Disterhoft JF; Gundersen HJG; Mcechron MD; Persina IS; Power JM; Van Der Zee EA; West MJ, 2000, 'Remodeling of hippocampal synapses after hippocampus-dependent associative learning', Journal of Comparative Neurology, vol. 417, pp. 49 - 59, http://dx.doi.org/10.1002/(SICI)1096-9861(20000131)417:1<49::AID-CNE4>3.0.CO;2-3
2000
Oh MM; Power JM; Thompson LT; Disterhoft JF, 2000, 'Apamin increases excitability of CA1 hippocampal pyramidal neurons', Neuroscience Research Communications, vol. 27, pp. 135 - 142, http://dx.doi.org/10.1002/1520-6769(200009/10)27:2<135::AID-NRC7>3.0.CO;2-X
2000
Weiss C; Knuttinen MG; Power JM; Patel RI; O'Connor MS; Disterhoft JF, 1999, 'Trace eyeblink conditioning in the freely moving rat: Optimizing the conditioning parameters', Behavioral Neuroscience, vol. 113, pp. 1100 - 1105, http://dx.doi.org/10.1037/0735-7044.113.5.1100
1999
Weiss C; Knuttinen M-G; Power JM; Patel RI; O'Connor MS; Disterhoft JF, 1999, 'Trace eyeblink conditioning in the freely moving rat: Optimizing the conditioning parameters.', Behavioral Neuroscience, vol. 113, pp. 1100 - 1105, http://dx.doi.org/10.1037//0735-7044.113.5.1100
1999
Weiss C; Bouwmeester H; Power JM; Disterhoft JF, 1999, 'Hippocampal lesions prevent trace eyeblink conditioning in the freely moving rat', Behavioural Brain Research, vol. 99, pp. 123 - 132, http://dx.doi.org/10.1016/S0166-4328(98)00096-5
1999
Disterhoft JF; Kronforst-Collins M; Oh MM; Power JM; Preston AR; Weiss C, 1999, 'Cholinergic facilitation of trace eyeblink conditioning in aging rabbits', Life Sciences, vol. 64, pp. 541 - 548, http://dx.doi.org/10.1016/S0024-3205(98)00599-2
1999
Oh MM; Power JM; Thompson LT; Moriearty PL; Disterhoft JF, 1999, 'Metrifonate increases neuronal excitability in CA1 pyramidal neurons from both young and aging rabbit hippocampus', Journal of Neuroscience, vol. 19, pp. 1814 - 1823
1999
Disterhoft JF; KronforstCollins MA; McEchron MD; Moyer JR; Power JM; Thompson LT, 1997, 'Mechanisms of associative learning in young and ageing hippocampus', JOURNAL OF PHYSIOLOGY-LONDON, vol. 501P, pp. S6 - S7, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1997XD09100236&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
1997
Power JM; Thompson LT; Moyer JR; Disterhoft JF, 1997, 'Enhanced synaptic transmission in CA1 hippocampus after eyeblink conditioning', Journal of Neurophysiology, vol. 78, pp. 1184 - 1187, http://dx.doi.org/10.1152/jn.1997.78.2.1184
1997
Dowse H; Ringo J; Power J; Kinney K; White L, 1995, 'A congenital heart defect in drosophila caused by an action-potential mutation', Journal of Neurogenetics, vol. 10, pp. 153 - 168, http://dx.doi.org/10.3109/01677069509083461
1995
Power JM; Ringo JM; Dowse HB, 1995, 'The Effects of Period Mutations and Light on the Activity Rhythms of Drosophila melanogaster', Journal of Biological Rhythms, vol. 10, pp. 267 - 280, http://dx.doi.org/10.1177/074873049501000309
1995
Power J; Ringo J; Dowse H, 1995, 'The role of light in the initiation of circadian activity rhythms of adult drosophila melanogaster', Journal of Neurogenetics, vol. 9, pp. 227 - 238, http://dx.doi.org/10.3109/01677069509084159
1995
Conference Papers
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Ong-Palsson E; Munro K; Teng K; Takeshima H; Lichtenthaler S; Power J; Gunnersen J, 2017, 'Seizure-related gene 6 (SEZ6) family proteins and their influence on excitatory synapse function, motor coordination and cognition', in JOURNAL OF NEUROCHEMISTRY, WILEY, Paris, FRANCE, pp. 191 - 191, presented at ISN-ESN Meeting, Paris, FRANCE, 20 August 2017 - 24 August 2017, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000407425300456&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2017
Gorlamandala N; Parmar J; Craig A; Power J; Krishnan A; Housley G, 2015, 'Spatiotemporal delineation of a cerebral photothrombotic infarct in mouse using darkfield microscopy', in JOURNAL OF NEUROCHEMISTRY, WILEY-BLACKWELL, Cairns, AUSTRALIA, pp. 292 - 292, presented at 25th Biennial Meeting of the International-Society-for-Neurochemistry Jointly with the 13th Meeting of the Asian-Pacific-Society-for-Neurochemistry in Conjunction with the 35th Meeting of the Australasian-Neuroscience-Society, Cairns, AUSTRALIA, 23 August 2015 - 27 August 2015, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000360206300736&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
2015
Disterhoft JF; Thompson LT; Weiss C; Moyer JR; Van der Zee E; Carrillo M; Kronforst-Collins M; Power J, 1995, 'The calcium hypothesis for Alzheimer's disease: Insights from animal and human studies', in Neuroscience Research Communications, pp. 121 - 131
1995
Conference Abstracts
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Harasta A; Power JM; von Jonquieres G; Karl T; Drucker DJ; Housley GD; Schneider M; Klugmann M, 2015, 'Septal glucagon-like peptide 1 receptor expression determines suppression of cocaine-induced behaviour', in JOURNAL OF NEUROCHEMISTRY, WILEY-BLACKWELL, Cairns, AUSTRALIA, Vol. 134, pp. 214 - 214, presented at 25th Biennial Meeting of the International-Society-for-Neurochemistry Jointly with the 13th Meeting of the Asian-Pacific-Society-for-Neurochemistry in Conjunction with the 35th Meeting of the Australasian-Neuroscience-Society, Cairns, AUSTRALIA, 23 August 2015 - 27 August 2015, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000360206300522&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2015
Khoshaba A; Power J; Inada H; Nabekura J; Moorhouse A, 2015, 'Measuring KCC2 function in brain slices using BCECF imaging', in JOURNAL OF NEUROCHEMISTRY, WILEY-BLACKWELL, Cairns, AUSTRALIA, Vol. 134, pp. 159 - 159, presented at 25th Biennial Meeting of the International-Society-for-Neurochemistry Jointly with the 13th Meeting of the Asian-Pacific-Society-for-Neurochemistry in Conjunction with the 35th Meeting of the Australasian-Neuroscience-Society, Cairns, AUSTRALIA, 23 August 2015 - 27 August 2015, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000360206300372&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
2015
Patents
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Housley GD; Kim YS; Bertrand PP; Moorhouse AJ; Wong AC; Craig A; Power J; Klugmann M; Krishnan AV; Morris R, 2012, Methods for inhibiting neuron apoptosis and necrosis” (filed by New South Innovations – (UNSW) – Au Provisional Patent Application No. 2012902920, 6 July 2012)., AUSTRALIA, 2012, Patent No. 2012902920, status:%20Applied%20for%20(Provisional)%20Registered%20in%20names%20of%20(Inventors)
2012
Kim Y; Bertrand P; Moorhouse A; Wong ACY; Craig A; Power J; Klugmann M; Krishnan A; Morris R, Methods for inhibiting neuron apoptosis and necrosis, Patent No. 2013286815