Jamie Vandenberg

Professor

Research Interests: Biophysics and pharmacology of cardiac ion channels. Genotype-Phenotype relationships in inherited arrhythmia syndromes. In silico modeling of inherited arrhythmia syndromes. Structural basis of drug binding to hERG K+ channels.

Professor Jamie Vandenberg completed his medical degree at the University of Sydney (1988) and his PhD in the Department of Biochemistry at the University of Cambridge (1994). He undertook postdoctoral studies in cardiac electrophysiology at the University of Oxford then moved to the University of Cambridge where he established an independent group looking at the molecular basis of cardiac arrhythmias. In 2002, he relocated to the Victor Chang Cardiac Research Institute, where he is currently Co-Deputy Director and Head of the Mark Cowley Lidwill Research Program in Cardiac Electrophysiology. He is a National Health and Medical Research Council Principal Research Fellow, and in 2015 was elected to the Fellowship of the Heart rhythm Society (USA) and the Australian Academy of Health and Medical Sciences. His research has focused on the molecular basis of cardiac electrical activity and understanding the genesis of cardiac arrhythmias and sudden cardiac death.  

Journal articles
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Jiang C; Richardson E; Farr J; Hill AP; Ullah R; Kroncke BM; Harrison SM; Thomson KL; Ingles J; Vandenberg JI; Ng C-A, 2022, 'A calibrated functional patch-clamp assay to enhance clinical variant interpretation in KCNH2-related long QT syndrome.', Am J Hum Genet, http://dx.doi.org/10.1016/j.ajhg.2022.05.002
2022
Ng CA; Vandenberg JI, 2022, 'When it takes two to get one into trouble', Heart Rhythm, vol. 19, pp. 293 - 294, http://dx.doi.org/10.1016/j.hrthm.2021.10.017
2022
Ng C-A; Ullah R; Farr J; Hill AP; Kozek KA; Vanags LR; Mitchell DW; Kroncke BM; Vandenberg JI, 2022, 'A massively parallel assay accurately discriminates between functionally normal and abnormal variants in a hotspot domain of KCNH2.', Am J Hum Genet, http://dx.doi.org/10.1016/j.ajhg.2022.05.003
2022
Windley MJ; Farr J; Tebay C; Vandenberg JI; Hill AP, 2022, 'Translating the measurement of hERG kinetics and drug block for CiPA to a high throughput platform.', J Pharmacol Toxicol Methods, pp. 107192, http://dx.doi.org/10.1016/j.vascn.2022.107192
2022
Kerr NP; Vandenberg JI, 2022, 'The yin and yang of Tbx5 variant effects on sodium channel function', Cardiovascular research, vol. 118, pp. 929 - 931, http://dx.doi.org/10.1093/cvr/cvac015
2022
TeBay C; McArthur JR; Mangala M; Kerr N; Heitmann S; Perry MD; Windley MJ; Vandenberg JI; Hill AP, 2022, 'Pathophysiological metabolic changes associated with disease modify the proarrhythmic risk profile of drugs with potential to prolong repolarisation', British Journal of Pharmacology, vol. 179, pp. 2631 - 2646, http://dx.doi.org/10.1111/bph.15757
2022
Peters S; Thompson BA; Perrin M; James P; Zentner D; Kalman JM; Vandenberg JI; Fatkin D, 2022, 'Arrhythmic Phenotypes Are a Defining Feature of Dilated Cardiomyopathy-Associated SCN5A Variants: A Systematic Review', Circulation: Genomic and Precision Medicine, vol. 15, pp. E003432, http://dx.doi.org/10.1161/CIRCGEN.121.003432
2022
Heitmann S; Shpak A; Vandenberg JI; Hill AP, 2021, 'Arrhythmogenic effects of ultra-long and bistable cardiac action potentials', PLoS Computational Biology, vol. 17, http://dx.doi.org/10.1371/JOURNAL.PCBI.1008683
2021
Ng C-A; Farr J; Young P; Windley M; Perry M; Hill A; Vandenberg J, 2021, 'Heterozygous KCNH2 variant phenotyping using Flp-In HEK293 and high-throughput automated patch clamp electrophysiology', , http://dx.doi.org/10.1101/2021.02.02.427891
2021
Ballouz S; Mangala MM; Perry MD; Heitmann S; Gillis JA; Hill AP; Vandenberg JI, 2021, 'Co-expression of calcium and hERG potassium channels reduces the incidence of proarrhythmic events', Cardiovascular Research, vol. 117, pp. 2216 - 2227, http://dx.doi.org/10.1093/cvr/cvaa280
2021
Ng CA; Farr J; Young P; Windley MJ; Perry MD; Hill AP; Vandenberg JI, 2021, 'Heterozygous KCNH2 variant phenotyping using Flp-In HEK293 and high-Throughput automated patch clamp electrophysiology', Biology Methods and Protocols, vol. 6, pp. bpab003, http://dx.doi.org/10.1093/biomethods/bpab003
2021
Perry MD; Ng CA; Mangala MM; Ng TYM; Hines AD; Liang W; Xu MJO; Hill AP; Vandenberg JI, 2020, 'Pharmacological activation of IKrin models of long QT Type 2 risks overcorrection of repolarization', Cardiovascular Research, vol. 116, pp. 1434 - 1445, http://dx.doi.org/10.1093/cvr/cvz247
2020
Li Z; Mirams GR; Yoshinaga T; Ridder BJ; Han X; Chen JE; Stockbridge NL; Wisialowski TA; Damiano B; Severi S; Morissette P; Kowey PR; Holbrook M; Smith G; Rasmusson RL; Liu M; Song Z; Qu Z; Leishman DJ; Steidl-Nichols J; Rodriguez B; Bueno-Orovio A; Zhou X; Passini E; Edwards AG; Morotti S; Ni H; Grandi E; Clancy CE; Vandenberg J; Hill A; Nakamura M; Singer T; Polonchuk L; Greiter-Wilke A; Wang K; Nave S; Fullerton A; Sobie EA; Paci M; Musuamba Tshinanu F; Strauss DG, 2020, 'General Principles for the Validation of Proarrhythmia Risk Prediction Models: An Extension of the CiPA In Silico Strategy', Clinical Pharmacology and Therapeutics, vol. 107, pp. 102 - 111, http://dx.doi.org/10.1002/cpt.1647
2020
Ng CA; Perry MD; Liang W; Smith NJ; Foo B; Shrier A; Lukacs GL; Hill AP; Vandenberg JI, 2020, 'High-throughput phenotyping of heteromeric human ether-à-go-go-related gene potassium channel variants can discriminate pathogenic from rare benign variants', Heart Rhythm, vol. 17, pp. 492 - 500, http://dx.doi.org/10.1016/j.hrthm.2019.09.020
2020
Ganesan AN; Vanoye CG; Alam F; Waddell-Smith KE; McGavigan AD; Correnti G; Haan E; Brown A; Vandenberg J; George AL, 2020, 'Long QT syndrome type 1 in an Australian indigenous patient', Circulation: Genomic and Precision Medicine, vol. 13, pp. 93 - 94, http://dx.doi.org/10.1161/CIRCGEN.119.002813
2020
Kozek KA; Glazer AM; Ng CA; Blackwell D; Egly CL; Vanags LR; Blair M; Mitchell D; Matreyek KA; Fowler DM; Knollmann BC; Vandenberg JI; Roden DM; Kroncke BM, 2020, 'High-throughput discovery of trafficking-deficient variants in the cardiac potassium channel KV11.1', Heart Rhythm, vol. 17, pp. 2180 - 2189, http://dx.doi.org/10.1016/j.hrthm.2020.05.041
2020
Lee W; Windley MJ; Perry MD; Vandenberg JI; Hill AP, 2019, 'Protocol-dependent differences in IC50 values measured in human ether-á-go-go–related gene assays occur in a predictable way and can be used to quantify state preference of drug binding', Molecular Pharmacology, vol. 95, pp. 537 - 550, http://dx.doi.org/10.1124/mol.118.115220
2019
Munawar S; Vandenberg JI; Jabeen I, 2019, 'Molecular docking guided grid-independent descriptor analysis to probe the impact ofwater molecules on conformational changes of hERG inhibitors in drug trapping phenomenon', International Journal of Molecular Sciences, vol. 20, http://dx.doi.org/10.3390/ijms20143385
2019
Tardo D; Peck M; Hill A; Vandenberg J, 2019, 'T Wave Morphology Biomarkers in Congenital and Acquired Long QT Syndrome', Heart, Lung and Circulation, vol. 28, pp. S229 - S229, http://dx.doi.org/10.1016/j.hlc.2019.06.223
2019
Ng T; Vandenberg J; Perry M, 2018, 'Pharmacological Activation of hERG Potassium Channels in Congenital Long QT Syndrome 2: Activator Compound ICA-105574 and its Effects on Mutant hERG Potassium Channels in Long QT Syndrome 2', Heart, Lung and Circulation, vol. 27, pp. S61 - S61, http://dx.doi.org/10.1016/j.hlc.2018.06.039
2018
Windley MJ; Lee W; Vandenberg JI; Hill AP, 2018, 'The temperature dependence of kinetics associated with drug block of hERG channels is compound-specific and an important factor for proarrhythmic risk prediction', Molecular Pharmacology, vol. 94, pp. 760 - 769, http://dx.doi.org/10.1124/mol.117.111534
2018
Lau C; Hunter MJ; Stewart A; Perozo E; Vandenberg JI, 2018, 'Never at rest: insights into the conformational dynamics of ion channels from cryo-electron microscopy', Journal of Physiology, vol. 596, pp. 1107 - 1119, http://dx.doi.org/10.1113/JP274888
2018
Lee W; Mangala M; Windley M; Perry M; Vandenberg J; Hill A, 2018, 'Novel Pre–Clinical Risk Prediction of Acquired Long QT Syndrome', Heart, Lung and Circulation, vol. 27, pp. S180 - S180, http://dx.doi.org/10.1016/j.hlc.2018.06.309
2018
Munawar S; Windley MJ; Tse EG; Todd MH; Hill AP; Vandenberg JI; Jabeen I, 2018, 'Experimentally validated pharmacoinformatics approach to predict hERG inhibition potential of new chemical entities', Frontiers in Pharmacology, vol. 9, http://dx.doi.org/10.3389/fphar.2018.01035
2018
Beattie KA; Hill AP; Bardenet R; Cui Y; Vandenberg JI; Gavaghan DJ; de Boer TP; Mirams GR, 2018, 'Sinusoidal voltage protocols for rapid characterisation of ion channel kinetics', Journal of Physiology, vol. 596, pp. 1813 - 1828, http://dx.doi.org/10.1113/JP275733
2018
Chiamvimonvat N; Chen-Izu Y; Clancy CE; Deschenes I; Dobrev D; Heijman J; Izu L; Qu Z; Ripplinger CM; Vandenberg JI; Weiss JN; Koren G; Banyasz T; Grandi E; Sanguinetti MC; Bers DM; Nerbonne JM, 2017, 'Potassium currents in the heart: functional roles in repolarization, arrhythmia and therapeutics', Journal of Physiology, vol. 595, pp. 2229 - 2252, http://dx.doi.org/10.1113/JP272883
2017
Vandenberg JI; Perozo E; Allen TW, 2017, 'Towards a Structural View of Drug Binding to hERG K+ Channels', Trends in Pharmacological Sciences, vol. 38, pp. 899 - 907, http://dx.doi.org/10.1016/j.tips.2017.06.004
2017
Phan K; Ng CA; David E; Shishmarev D; Kuchel PW; Vandenberg JI; Perry MD, 2017, 'The S1 helix critically regulates the finely tuned gating of Kv11.1 channels', Journal of Biological Chemistry, vol. 292, pp. 7688 - 7705, http://dx.doi.org/10.1074/jbc.M117.779298
2017
Vandenberg JI; Perry MD; Hill AP, 2017, 'Recent advances in understanding and prevention of sudden cardiac death', F1000Research, vol. 6, http://dx.doi.org/10.12688/f1000research.11855.1
2017
Lee W; Windley MJ; Vandenberg JI; Hill AP, 2017, 'In vitro and in silico risk assessment in acquired long QT syndrome: The devil is in the details', Frontiers in Physiology, vol. 8, http://dx.doi.org/10.3389/fphys.2017.00934
2017
Windley MJ; Abi-Gerges N; Fermini B; Hancox JC; Vandenberg JI; Hill AP, 2017, 'Measuring kinetics and potency of hERG block for CiPA', Journal of Pharmacological and Toxicological Methods, vol. 87, pp. 99 - 107, http://dx.doi.org/10.1016/j.vascn.2017.02.017
2017
Grandi E; Sanguinetti MC; Bartos DC; Bers DM; Chen-Izu Y; Chiamvimonvat N; Colecraft HM; Delisle BP; Heijman J; Navedo MF; Noskov S; Proenza C; Vandenberg JI; Yarov-Yarovoy V, 2017, 'Potassium channels in the heart: structure, function and regulation', Journal of Physiology, vol. 595, pp. 2209 - 2228, http://dx.doi.org/10.1113/JP272864
2017
Hodkinson EC; Neijts M; Sadrieh A; Imtiaz MS; Baumert M; Subbiah RN; Hayward CS; Boomsma D; Willemsen G; Vandenberg JI; Hill AP; De Geus E, 2016, 'Heritability of ECG biomarkers in the Netherlands twin registry measured from Holter ECGs', Frontiers in Physiology, vol. 7, http://dx.doi.org/10.3389/fphys.2016.00154
2016
Christensen AH; Chatelain FC; Huttner IG; Olesen MS; Soka M; Feliciangeli S; Horvat C; Santiago CF; Vandenberg JI; Schmitt N; Olesen SP; Lesage F; Fatkin D; Martin I, 2016, 'The two-pore domain potassium channel, TWIK-1, has a role in the regulation of heart rate and atrial size', Journal of Molecular and Cellular Cardiology, vol. 97, pp. 24 - 35, http://dx.doi.org/10.1016/j.yjmcc.2016.04.006
2016
Ng CA; Gravel AE; Perry MD; Arnold AA; Marcotte I; Vandenberg JI, 2016, 'Tyrosine residues from the s4-s5 linker of kv11.1 channels are critical for slow deactivation', Journal of Biological Chemistry, vol. 291, pp. 17293 - 17302, http://dx.doi.org/10.1074/jbc.M116.729392
2016
Perry MD; Vandenberg JI, 2016, 'TECRL: Connecting sequence to consequence for a new sudden cardiac death gene', EMBO Molecular Medicine, vol. 8, pp. 1364 - 1365, http://dx.doi.org/10.15252/emmm.201606967
2016
Perry MD; Ng CA; Phan K; David E; Steer K; Hunter MJ; Mann SA; Imtiaz M; Hill AP; Ke Y; Vandenberg JI, 2016, 'Rescue of protein expression defects may not be enough to abolish the pro-arrhythmic phenotype of long QT type 2 mutations', Journal of Physiology, vol. 594, pp. 4031 - 4049, http://dx.doi.org/10.1113/JP271805
2016
Hill AP; Perry MD; Abi-Gerges N; Couderc JP; Fermini B; Hancox JC; Knollmann BC; Mirams GR; Skinner J; Zareba W; Vandenberg JI, 2016, 'Computational cardiology and risk stratification for sudden cardiac death: one of the grand challenges for cardiology in the 21st century', Journal of Physiology, vol. 594, pp. 6893 - 6908, http://dx.doi.org/10.1113/JP272015
2016
Mann SA; Imtiaz M; Winbo A; Rydberg A; Perry MD; Couderc JP; Polonsky B; McNitt S; Zareba W; Hill AP; Vandenberg JI, 2016, 'Convergence of models of human ventricular myocyte electrophysiology after global optimization to recapitulate clinical long QT phenotypes', Journal of Molecular and Cellular Cardiology, vol. 100, pp. 25 - 34, http://dx.doi.org/10.1016/j.yjmcc.2016.09.011
2016
Immanuel S; Sadrieh A; Baumert M; Couderc J; Zareba W; Hill A; Vandenberg J, 2016, 'T Wave Morphology Can Distinguish Healthy Controls From LQTS Patients With Normal QT Intervals', Heart, Lung and Circulation, vol. 25, pp. S262 - S262, http://dx.doi.org/10.1016/j.hlc.2016.06.610
2016
Fermini B; Hancox JC; Abi-Gerges N; Bridgland-Taylor M; Chaudhary KW; Colatsky T; Correll K; Crumb W; Damiano B; Erdemli G; Gintant G; Imredy J; Koerner J; Kramer J; Levesque P; Li Z; Lindqvist A; Obejero-Paz CA; Rampe D; Sawada K; Strauss DG; Vandenberg JI, 2016, 'A new perspective in the field of cardiac safety testing through the comprehensive in vitro proarrhythmia assay paradigm', Journal of Biomolecular Screening, vol. 21, pp. 1 - 11, http://dx.doi.org/10.1177/1087057115594589
2016
Heide J; Zhang F; Bigos KL; Mann SA; Carr VJ; Weickert CS; Green MJ; Weinberger DR; Vandenberg JI, 2016, 'Differential response to risperidone in schizophrenia patients by KCNH2Genotype and drug metabolizer status', American Journal of Psychiatry, vol. 173, pp. 53 - 59, http://dx.doi.org/10.1176/appi.ajp.2015.14050653
2016
Lee W; Mann SA; Windley MJ; Imtiaz MS; Vandenberg JI; Hill AP, 2016, 'In silico assessment of kinetics and state dependent binding properties of drugs causing acquired LQTS', Progress in Biophysics and Molecular Biology, vol. 120, pp. 89 - 99, http://dx.doi.org/10.1016/j.pbiomolbio.2015.12.005
2016
Immanuel SA; Sadrieh A; Baumert M; Couderc JP; Zareba W; Hill AP; Vandenberg JI, 2016, 'T-wave morphology can distinguish healthy controls from LQTS patients', Physiological Measurement, vol. 37, pp. 1456 - 1473, http://dx.doi.org/10.1088/0967-3334/37/9/1456
2016
Windley MJ; Mann SA; Vandenberg JI; Hill AP, 2016, 'Temperature effects on kinetics of KV11.1 drug block have important consequences for in silico proarrhythmic risk prediction', Molecular Pharmacology, vol. 90, pp. 1 - 11, http://dx.doi.org/10.1124/mol.115.103127
2016
Heide J; Vandenberg JI; Weickert CS, 2015, 'Expression of KCNH2-3.1 mRNA is increased in small neurons in the dorsolateral prefrontal cortex in patients with schizophrenia', European Journal of Psychiatry, vol. 29, pp. 85 - 103, http://dx.doi.org/10.4321/S0213-61632015000200001
2015
Fonoudi H; Ansari H; Abbasalizadeh S; Larijani MR; Kiani S; Hashemizadeh S; Zarchi AS; Bosman A; Blue GM; Pahlavan S; Perry M; Orr Y; Mayorchak Y; Vandenberg J; Talkhabi M; Winlaw DS; Harvey RP; Aghdami N; Baharvand H, 2015, 'A universal and robust integrated platform for the scalable production of human cardiomyocytes from pluripotent stem cells', Stem Cells Translational Medicine, vol. 4, pp. 1482 - 1494, http://dx.doi.org/10.5966/sctm.2014-0275
2015
Perry MD; Ng CA; Mann SA; Sadrieh A; Imtiaz M; Hill AP; Vandenberg JI, 2015, 'Getting to the heart of hERG K+ channel gating', Journal of Physiology, vol. 593, pp. 2575 - 2585, http://dx.doi.org/10.1113/JP270095
2015
Hodkinson EC; Hill AP; Vandenberg JI, 2014, 'The Romano-Ward syndrome--1964-2014: 50 years of progress.', Irish medical journal, vol. 107, pp. 122 - 124
2014
Sadrieh A; Domanski L; Pitt-Francis J; Mann SA; Hodkinson EC; Ng CA; Perry MD; Taylor JA; Gavaghan D; Subbiah RN; Vandenberg JI; Hill AP, 2014, 'Multiscale cardiac modelling reveals the origins of notched T waves in long QT syndrome type 2', Nature Communications, vol. 5, http://dx.doi.org/10.1038/ncomms6069
2014
Hill AP; Perrin MJ; Heide J; Campbell TJ; Mann SA; Vandenberg JI, 2014, 'Kinetics of drug interaction with the Kv11.1 potassium channel', Molecular Pharmacology, vol. 85, pp. 769 - 776, http://dx.doi.org/10.1124/mol.114.091835
2014
Ke Y; Hunter MJ; Ng CA; Perry MD; Vandenberg JI, 2014, 'Role of the cytoplasmic N-terminal cap and Per-Arnt-Sim (PAS) domain in trafficking and stabilization of Kv11.1 channels', Journal of Biological Chemistry, vol. 289, pp. 13782 - 13791, http://dx.doi.org/10.1074/jbc.M113.531277
2014
Ng CA; Phan K; Hill AP; Vandenberg JI; Perry MD, 2014, 'Multiple interactions between cytoplasmic domains regulate slow deactivation of Kv11.1 channels', Journal of Biological Chemistry, vol. 289, pp. 25822 - 25832, http://dx.doi.org/10.1074/jbc.M114.558379
2014
Vandenberg JI; Perry MD, 2014, 'Can many subunits make light work of ion channel inactivation?', Journal of Physiology, vol. 592, pp. 4411 - 4412, http://dx.doi.org/10.1113/jphysiol.2014.281568
2014
Vandenberg J, 2013, '2SDP-03 Ion channel gating and Japanese Puzzle Boxes(2SDP ASB-BSJ Bilateral Symposium 2013,Symposium,The 51th Annual Meeting of the Biophysical Society of Japan)', Seibutsu Butsuri, vol. 53, pp. S99 - S99, http://dx.doi.org/10.2142/biophys.53.s99_3
2013
Martin I; Trivedi G; Jacoby A; Mann S; Vandenberg J; Fatkin D, 2013, 'A Transgenic Zebrafish Model of a Human Cardiac Sodium Channel Mutation Exhibits Bradycardia, Conduction-System Abnormalities and Early Death', Heart, Lung and Circulation, vol. 22, pp. S227 - S227, http://dx.doi.org/10.1016/j.hlc.2013.05.539
2013
Perry MD; Wong S; Ng CA; Vandenberg JI, 2013, 'Hydrophobic interactions between the voltage sensor and pore mediate inactivation in Kv11.1 channels', Journal of General Physiology, vol. 142, pp. 275 - 288, http://dx.doi.org/10.1085/jgp.201310975
2013
Ng CA; Ke Y; Perry MD; Tan PS; Hill AP; Vandenberg JI, 2013, 'C-Terminal β9-Strand of the Cyclic Nucleotide-Binding Homology Domain Stabilizes Activated States of Kv11.1 Channels', PLoS ONE, vol. 8, http://dx.doi.org/10.1371/journal.pone.0077032
2013
Liang B; Soka M; Christensen AH; Olesen MS; Larsen AP; Knop FK; Wang F; Nielsen JB; Andersen MN; Humphreys D; Mann SA; Huttner IG; Vandenberg JI; Svendsen JH; Haunsø S; Preiss T; Seebohm G; Olesen SP; Schmitt N; Fatkin D, 2013, 'Genetic variation in the two-pore domain potassium channel, TASK-1, may contribute to an atrial substrate for arrhythmogenesis.', J Mol Cell Cardiol, vol. 67, pp. 69 - 76, http://dx.doi.org/10.1016/j.yjmcc.2013.12.014
2013
Ke Y; Ng CA; Hunter MJ; Mann SA; Heide J; Hill AP; Vandenberg JI, 2013, 'Trafficking defects in PAS domain mutant Kv11.1 channels: Roles of reduced domain stability and altered domain-domain interactions', Biochemical Journal, vol. 454, pp. 69 - 77, http://dx.doi.org/10.1042/BJ20130328
2013
Huttner IG; Trivedi G; Jacoby A; Mann SA; Vandenberg JI; Fatkin D, 2013, 'A transgenic zebrafish model of a human cardiac sodium channel mutation exhibits bradycardia, conduction-system abnormalities and early death', Journal of Molecular and Cellular Cardiology, vol. 61, pp. 123 - 132, http://dx.doi.org/10.1016/j.yjmcc.2013.06.005
2013
Olesen M; Liang B; Soka M; Larsen AP; Knop FK; Wang F; Nielsen JB; Andersen MN; Humphreys D; Mann SA; Vandenberg JI; Svendsen JH; Haunso S; Preiss T; Seebohm G; Olesen S-P; Schmitt N; Fatkin D, 2013, 'TASK-1 potassium channel mutations in atrial fibrillation', European Heart Journal, vol. 34, pp. 3411 - 3411, http://dx.doi.org/10.1093/eurheartj/eht309.3411
2013
Mann S; Sadrieh A; Subbiah R; Domanski L; Taylor J; Vandenberg J; Hill A, 2013, 'Epistatic Interactions of Ion Channels Underlie Variability in Cardiac Electrical Activity. In-silico Analysis of the Electrocardiogram', Heart, Lung and Circulation, vol. 22, pp. S95 - S96, http://dx.doi.org/10.1016/j.hlc.2013.05.226
2013
Sadrieh A; Mann SA; Subbiah RN; Domanski L; Taylor JA; Vandenberg JI; Hill AP, 2013, 'Quantifying the origins of population variability in cardiac electrical activity through sensitivity analysis of the electrocardiogram', Journal of Physiology, vol. 591, pp. 4207 - 4222, http://dx.doi.org/10.1113/jphysiol.2013.251710
2013
Heide J; Mann SA; Vandenberg JI, 2012, 'The Schizophrenia-Associated Kv11.1-3.1 Isoform Results in Reduced Current Accumulation during Repetitive Brief Depolarizations', PLoS ONE, vol. 7, pp. e45624, http://dx.doi.org/10.1371/journal.pone.0045624
2012
Mann SA; Otway R; Guo G; Soka M; Karlsdotter L; Trivedi G; Ohanian M; Zodgekar P; Smith RA; Wouters MA; Subbiah RN; Walker BD; Kuchar D; Sanders P; Griffiths LR; Vandenberg JI; Fatkin D, 2012, 'Epistatic effects of potassium channel variation on cardiac repolarization and atrial fibrillation risk', Journal of the American College of Cardiology, vol. 59, pp. 1017 - 1025, http://dx.doi.org/10.1016/j.jacc.2011.11.039
2012
Tan PS; Perry MD; Ng C; Vandenberg JI; Hill A, 2012, 'Voltage-sensing domain mode shift is coupled to the activation gate by the N-terminal tail of hERG channels', Journal of General Physiology, vol. 140, pp. 293 - 306, http://dx.doi.org/10.1085/jgp.201110761
2012
Ng CA; Perry M; Tan P; Hill A; Kuchel PW; Vandenberg JI, 2012, 'The S4-S5 linker acts as a signal integrator for HERG K+ channel activation and deactivation gating', PLoS ONE, vol. 7, pp. e31640, http://dx.doi.org/10.1371/journal.pone.0031640
2012
Vandenberg JI; Mann SA; Castro ML; Ohanian M; Guo G; Zodgekar PR; Sheu A; Stockhammer K; Fatkin D; Subbiah RN, 2012, 'R222Q SCN5A Mutation Is Associated With Reversible Ventricular Ectopy and Dilated Cardiomyopathy', Journal of the American College of Cardiology, vol. 60, pp. 1566 - 1573, http://dx.doi.org/10.1016/j.jacc.2012.05.050
2012
Vandenberg JI; Perry MD; Mann SA; Hill A, 2012, 'hERG K+ CHANNELS: STRUCTURE, FUNCTION, AND CLINICAL SIGNIFICANCE', Physiological Reviews, vol. 92, pp. 1393 - 1478, http://dx.doi.org/10.1152/physrev.00036.2011
2012
Vandenberg JI; Ng CA, 2012, 'Insights into hERG K+ channel structure and function from NMR studies', European Biophysics Journal With Biophysics Letters, vol. 42, pp. 71 - 79, http://dx.doi.org/10.1007/s00249-012-0808-6
2012
Vandenberg JI, 2012, 'Hodgkin and Huxley and the basis for electrical signalling: a remarkable legacy still going strong', The Journal of Physiology, vol. 590, pp. 2569 - 2570, http://dx.doi.org/10.1113/jphysiol.2012.233411
2012
Vandenberg JI, 2012, 'Is medroxyprogesterone safe in women with long QT syndrome?', Heart Rhythm, vol. 9, pp. 1148 - 1149, http://dx.doi.org/10.1016/j.hrthm.2012.02.029
2012
Ng C; Hunter M; Perry M; Mobli M; Ke Y; Kuchel PW; King GF; Stock D; Vandenberg JI; Hunter M, 2011, 'The N-terminal tail of hERG contains an amphipathic alpha-helix that regulates channel deactivation', PLoS One, vol. 6, pp. e16191, http://dx.doi.org/10.1371/journal.pone.0016191
2011
Szekely D; Vandenberg JI; Dokos S; Hill A, 2011, 'An improved curvilinear gradient method for parameter optimization in complex biological models', Medical and Biological Engineering and Computing, vol. 49, pp. 289 - 296, http://dx.doi.org/10.1007/s11517-010-0667-1
2011
Wang DT; Hill A; Mann SA; Tan P; Vandenberg JI, 2010, 'Mapping the sequence of conformational changes underlying selectivity filter gating in the K(v)11.1 potassium channel', Nature Structural and Molecular Biology, vol. 18, pp. 35 - 41, http://dx.doi.org/10.1038/nsmb.1966
2010
Clarke O; Caputo A; Hill A; Vandenberg JI; Smith B; Gulbis J, 2010, 'Domain reorientation and rotation of an intracellular assembly regulate conduction in Kir potassium channels', Cell, vol. 141, pp. 1018 - 1029, http://dx.doi.org/10.1016/j.cell.2010.05.003
2010
Ju P; Pages G; Riek RP; Chen P-C; Torres A; Bansal PS; Kuyucak S; Kuchel PW; Vandenberg JI, 2009, 'The pore domain outer helix contributes to both activation and inactivation of the hERG K+ channel', The Journal of Biological Chemistry, vol. 284, pp. 1000 - 1006, http://dx.doi.org/10.1074/jbc.M806400200
2009
Zhao JT; Hill A; Varghese A; Cooper A; Swan H; Laitinen-Forsblom P; Rees M; Skinner J; Campbell TJ; Vandenberg JI, 2009, 'Not all hERG pore domain mutations have a severe phenotype: G584S has an inactivation gating defect with mild phenotype compared to G572S, which has a dominant negative trafficking defect and a severe phenotype', Journal of Cardiovascular Electrophysiology, vol. 20, pp. 923 - 930, http://dx.doi.org/10.1111/j.1540-8167.2009.01468.x
2009
Perrin MJ; Campbell TJ; Hill AP; Vandenberg JI, 2009, 'Insight into Accurate Testing of Drugs which Cause the Acquired Long-QT Syndrome', Heart, Lung and Circulation, vol. 18, pp. S135 - S135, http://dx.doi.org/10.1016/j.hlc.2009.05.306
2009
Pages G; Torres A; Ju P; Bansal PS; Alewood P; Kuchel PW; Vandenberg JI, 2009, 'Structure of the pore-helix of the hERG K(+) channel', European Biophysics Journal, vol. 39, pp. 111 - 120, http://dx.doi.org/10.1007/s00249-009-0433-1
2009
Bansal PS; Torres A; Crossett B; Wong KK; Koh JM; Geraghty D; Vandenberg JI; Kuchel PW, 2008, 'Substrate specificity of platypus venom L-to-D-peptide isomerase', The Journal of Biological Chemistry, vol. 283, pp. 8969 - 8975, http://dx.doi.org/10.1074/jbc.M709762200
2008
Clarke CE; Veale E; Wyse KR; Vandenberg JI; Mathie A, 2008, 'The M1P1 loop of TASK3 K2P channels apposes the selectivity filter and influences channel function', The Journal of Biological Chemistry, vol. 283, pp. 16985 - 16992, http://dx.doi.org/10.1074/jbc.M801368200
2008
Perrin MJ; Subbiah RN; Vandenberg JI; Hill A, 2008, 'Human ether-a-go-go related gene (hERG) K+ channels: Function and dysfunction', Progress in Biophysics and Molecular Biology, vol. 98, pp. 137 - 148, http://dx.doi.org/10.1016/j.pbiomolbio.2008.10.006
2008
Kuchel PW; Perrin MJ; Campbell TJ; Vandenberg JI, 2008, 'Drug Binding to the Inactivated State Is Necessary but Not Sufficient for High-Affinity Binding to Human Ether-a-go-go-Related Gene Channels', Molecular Pharmacology, vol. 74, pp. 1443 - 1452, http://dx.doi.org/10.1124/mol.108.049056
2008
Fatkin D; Otway R; Vandenberg JI, 2007, 'Genes and atrial fibrillation - A new look at an old problem', Circulation, vol. 116, pp. 782 - 792, http://dx.doi.org/10.1161/CIRCULATIONAHA.106.688889
2007
Hill A; Sunde M; Campbell TJ; Vandenberg JI, 2007, 'Mechanism of block of the hERG K+ channel by the scorpion toxin CnErg1', Biophysical Journal, vol. 92, pp. 3915 - 3929, http://dx.doi.org/10.1529/biophysj.106.101956
2007
Hill A; Sunde M; Vandenberg JI, 2007, 'Mechanisms of block of the hERG K+ channel by the scorpion toxin CnErg1', Biophysical Journal, pp. 124A - 124A, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000243972400570&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
2007
Otway R; Vandenberg JI; Guo G; Varghese A; Castro ML; Liu JJ; Zhao J; Bursill JA; Wyse KR; Crotty H; Baddeley O; Walker BD; Kuchar D; Thorburn CW; Fatkin D, 2007, 'Stretch-sensitive KCNQ1 mutation - A link between genetic and environmental factors in the pathogenesis of atrial fibrillation?', Journal of the American College of Cardiology, vol. 49, pp. 578 - 586, http://dx.doi.org/10.1016/j.jacc.2006.09.044
2007
Hill A; Campbell TJ; Bansal PS; Kuchel PW; Vandenberg JI, 2007, 'The S631A mutation causes a mechanistic switch in the block of hERG channels by CnErgl', Biophysical Journal, vol. 93, pp. 32 - 34, http://dx.doi.org/10.1529/biophysj.107.114561
2007
Otway R; Vandenberg JI; Fatkin D, 2007, 'Atrial Fibrillation-A New Cardiac Channelopathy', Heart Lung and Circulation, vol. 16, pp. 356 - 360, http://dx.doi.org/10.1016/j.hlc.2007.07.003
2007
Kutteh R; Vandenberg JI; Kuyucak S, 2007, 'Molecular dynamics and continuum electrostatics studies of inactivation in the HERG potassium channel', Journal of Physical Chemistry B, vol. 111, pp. 1090 - 1098, http://dx.doi.org/10.1021/jp066294d
2007
Clarke CE; Hill A; Kondo M; Subbiah RN; Campbell TJ; Vandenberg JI, 2006, 'Effect of S5P alpha-helix charge mutants on inactivation of hERG K+ channels', The Journal of Physiology, vol. 573, pp. 291 - 304, http://dx.doi.org/10.1113/jphysiol.2006.108332
2006
Vandenberg JI; Varghese A; Lu Y; Bursill JA; Mahaut-Smith MP; Huang CL, 2006, 'Temperature dependence of human ether-a-go-go-related gene K+ currents', American Journal of Physiology - Cell Physiology, vol. 291, pp. C165 - C175, http://dx.doi.org/10.1152/ajpcell.00596.2005
2006
Subbiah RN; Campbell TJ; Vandenberg JI, 2005, 'Ion channelopathies: What have they taught us about arrhythmias and anti-arrhythmic therapy', Clinical and Experimental Pharmacology and Physiology, vol. 32, pp. 595 - 595, http://dx.doi.org/10.1111/j.1440-1681.2005.04236.x
2005
Lei M; Goddard C; Liu J; Leoni A; Royer A; Fung SS; Xiao G; Ma A; Zhang H; Charpentier F; Vandenberg JI; Colledge WH; Grace AA; Huang SH, 2005, 'Sinus node dysfunction following targeted disruption of the murine cardiac sodium channel gene Scn5a', The Journal of Physiology, vol. 567, pp. 387 - 400, http://dx.doi.org/10.1113/jphysiol.2005.083188
2005
Subbiah RN; Kondo M; Campbell TJ; Vandenberg JI, 2005, 'Tryptophan scanning mutagenesis of the HERG K+ channel: the S4 domain is loosely packed and likely to be lipid exposed', The Journal of Physiology, vol. 569, pp. 367 - 379, http://dx.doi.org/10.1113/jphysiol.2005.097386
2005
Martinez-Pinna J; Tolhurst G; Gurung I; Vandenberg JI; Mahaut-Smith MP, 2004, 'Sensitivity limits for voltage control of P2Y receptor-evoked Ca2+mobilization in the rat megakaryocyte', The Journal of Physiology, vol. 555, pp. 61 - 70, http://dx.doi.org/10.1113/jphysiol.2003.056846
2004
Davies W; Vandenberg JI; Sayeed R; Trezise AE, 2004, 'Cardiac expression of the cystic fibrosis transmembrane conductanceregulator involves novel Exon 1 usage to produce a uniqueamino-terminal protein', The Journal of Biological Chemistry, vol. 279, pp. 15877 - 15887, http://dx.doi.org/10.1074/jbc.M313628200
2004
Vandenberg JI; Torres M; Campbell TJ; Kuchel PW, 2004, 'The HERGK+ channel: Progress in understanding the molecular basis of its unusual gating kinetics.', European Biophysics Journal With Biophysics Letters, vol. 33, pp. 80 - 97
2004
Subbiah RN; Clarke CE; Smith DG; Zha J; Campbell TJ; Vandenberg JI, 2004, 'Molecular basis of slow activation of the human ether-a-go-go relatedgene potassium channel', The Journal of Physiology, vol. 558, pp. 417 - 431, http://dx.doi.org/10.1113/jphysiol.2004.062588
2004
Davies W; Vandenberg JI; Sayeed R; Trezise AE, 2004, 'Post-transcriptional regulation of the cystic fibrosis gene in cardiac development and hypertrophy', Biochemical and Biophysical Research Communications, vol. 319, pp. 410 - 418, http://dx.doi.org/10.1016/j.bbrc.2004.05.008
2004
Subbiah RN; Campbell TJ; Vandenberg JI, 2004, 'Inherited cardiac arrhythmia syndromes: What have they taught us aboutarrhythmias and anti-arrhythmic therapy?', Clinical and Experimental Pharmacology and Physiology, vol. 31, pp. 906 - 912, http://dx.doi.org/10.1111/j.1440-1681.2004.04132.x
2004
Fahmi A; Forhead A; Fowden A; Vandenberg JI, 2004, 'Cortisol influences the ontogeny of both alpha- and beta-subunits ofthe cardiac sodium channel in fetal sheep', Journal of Endocrinology, vol. 180, pp. 449 - 455, http://dx.doi.org/10.1677/joe.0.1800449
2004
Vandenberg JI; Torres AM; Campbell TJ; Kuchel PW, 2004, 'The HERG K+ channel: Progress in understanding the molecular basis of its unusual gating kinetics', European Biophysics Journal, vol. 33, pp. 89 - 97, http://dx.doi.org/10.1007/s00249-003-0338-3
2004
Vandenberg JI; Torres AM; Campbell TJ; Kuchel PW, 2004, 'The HERG K+ channel: progress in understanding the molecular basis of its unusual gating kinetics (vol 33, pg 89, 2004)', EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS, vol. 33, pp. 468 - 468, http://dx.doi.org/10.1007/s00249-004-0419-y
2004
Vandenberg JI; Torres AM; Campbell TJ; Kuchel PW, 2004, 'Erratum: The HERG K+ channel: Progress in understanding the molecular basis of its unusual gating kinetics (European Biophysics Journal (2004) 33 (89-97))', European Biophysics Journal, vol. 33, pp. 468
2004
Singarayar SB; Bursill JA; Wyse KR; Bauskin AR; Wu WM; Vandenberg JI; Breit SN; Campbell TJ, 2003, 'Extracellular acidosis modulates drug block of Kv4.3 currents by flecainide and quinidine', Journal of Cardiovascular Electrophysiology, vol. 14, pp. 641 - 650, http://dx.doi.org/10.1046/j.1540-8167.2003.03026.x
2003
Torres M; Bansal PS; Sunde M; Clarke CE; Bursill JA; Smith DG; Bauskin AR; Breit SN; Campbell TJ; Alewood P; Kuchel PW; Vandenberg JI, 2003, 'Structure of the HERGK+ channel S5P extracellulal linker: Role of an amphipathic a-helix in C-type inactivation.', Journal of Biochemistry, vol. 278, pp. 42136 - 42148, http://dx.doi.org/10.1074/jbc.M212824200
2003
Lu Y; Mahaut-Smith MP; Huang CL; Vandenberg JI, 2003, 'Mutant MiRP1 subunits modulate HERG K+ channel gating: A mechanism for pro-arrhythmia in Long QT Syndrome type 6', Journal of Physiology - Paris, vol. 551, pp. 253 - 262, http://dx.doi.org/10.1113/jphysiol.2003.046045
2003
Vandenberg JI; Kuchel PW, 2003, 'Nobel Prizes for Magnetic Resonance Imaging and Channel Proteins', Medical Journal of Australia, vol. 179, pp. 611 - 613
2003
Torres A; Bansal PS; Alewood P; Bursill JA; Vandenberg JI; Kuchel PW, 2003, 'Solution structure of CnErg1 (Ergtoxin), a HERG specific scorpion toxin', FEBS Letters, vol. 539, pp. 138 - 142, http://dx.doi.org/10.1016/S0014-5793(03)00216-3
2003
Balasubramaniam RN; Grace AA; Saumarez R; Vandenberg JI; Huang CL, 2003, 'Electrogram prolongation and nifedipine-suppressible ventricular arrhythmias following targeted disruption of KCNE1', Journal of Physiology - Paris, vol. 552, pp. 535 - 546, http://dx.doi.org/10.1113/jphysiol.2003.048249
2003
Papadatos GA; Wallerstein PMR; Head CEG; Ratcliff R; Brady PA; Benndorf K; Saumarez RC; Trezise AEO; Huang CLH; Vandenberg JI; Colledge WH; Grace AA, 2002, 'Slowed conduction and ventricular tachycardia after targeted disruption of the cardiac sodium channel gene Scn5a', Proceedings of the National Academy of Sciences of the United States of America, vol. 99, pp. 6210 - 6215, http://dx.doi.org/10.1073/pnas.082121299
2002
Zhao J; Pettigrew GJ; Thomas J; Vandenberg JI; Delriviere L; Bolton EM; Carmichael A; Martin JL; Marber MS; Lever AML, 2002, 'Lentiviral vectors for delivery of genes into neonatal and adult ventricular cardiac myocytes in vitro and in vivo', Basic Research in Cardiology, vol. 97, pp. 348 - 358, http://dx.doi.org/10.1007/s00395-002-0360-0
2002
Vandenberg JI; Walker BD; Campbell TJ, 2001, 'HERG K+ channels: Friend and foe', Trends in Pharmacological Sciences, vol. 22, pp. 240 - 246, http://dx.doi.org/10.1016/S0165-6147(00)01662-X
2001
Fahmi AI; Patel M; Stevens EB; Fowden AL; John JE; Lee K; Pinnock R; Morgan K; Jackson AP; Vandenberg JI, 2001, 'The sodium channel β-subunits SCN3b modulates the kinetics of SCN5a and is expressed heterogeneously in sheep heart', Journal of Physiology, vol. 537, pp. 693 - 700, http://dx.doi.org/10.1113/jphysiol.2001.012691
2001
Lu Y; Mahaut-Smith MP; Varghese A; Huang CL-H; Kemp PR; Vandenberg JI, 2001, 'Effects of premature stimulation on HERG K+ channels', The Journal of Physiology, vol. 537, pp. 843 - 851, http://dx.doi.org/10.1113/jphysiol.2001.012690
2001
Yu Lu M; Mahaut-Smith P; Varghese A; Huang CLH; Kemp PR; Vandenberg JI, 2001, 'Effects of premature stimulation on HERG K+ channels', Journal of Physiology, vol. 537, pp. 843 - 851, http://dx.doi.org/10.1113/jphysiol.2001.012690
2001
Sheikh SM; Skepper JN; Chawla S; Vandenberg JI; Elneil S; Huang CL, 2001, 'Normal conduction of surface action potentials in detubulated amphibian skeletal muscle fibres.', J Physiol, vol. 535, pp. 579 - 590, http://dx.doi.org/10.1111/j.1469-7793.2001.t01-1-00579.x
2001
Vandenberg J; Sheikh SM; Skepper JN; Chawla S; Elneil S; Huang CL, 2001, 'Normal conduction of surface action potentials in detubulated amphibian skeletal muscle fibres.', The Journal of Physiology, vol. 535, pp. 579 - 590, http://dx.doi.org/10.1111/j.1469-7793.2001.t01-1-00579.x
2001
Smith GA; Vandenberg JI; Freestone NS; Dixon HBF, 2001, 'The effect of Mg2+ on cardiac muscle function: Is CaATP the substrate for priming myofibril cross-bridge formation and Ca2+ reuptake by the sarcoplasmic reticulum?', Biochemical Journal, vol. 354, pp. 539 - 551, http://dx.doi.org/10.1042/0264-6021:3540539
2001
Vandenberg JI; Lummis SCR, 2000, 'Ion channels - A plethora of pharmaceutical targets', Trends in Pharmacological Sciences, vol. 21, pp. 409 - 410, http://dx.doi.org/10.1016/S0165-6147(00)01558-3
2000
Keevil VL; Huang CL-H; Chau P-L; Sayeed RA; Vandenberg JI, 2000, 'The effect of heptanol on the electrical and contractile function of the isolated, perfused rabbit heart', Pflügers Archiv, vol. 440, pp. 275 - 275, http://dx.doi.org/10.1007/s004240051049
2000
Smith GA; Dixon HBF; Kirschenlohr HL; Grace AA; Metcalfe JC; Vandenberg JI, 2000, 'Ca2+ buffering in the heart: Ca2+ binding to and activation of cardiac myofibrils', Biochemical Journal, vol. 346, pp. 393 - 402, http://dx.doi.org/10.1042/0264-6021:3460393
2000
Kirschenlohr HL; Grace AA; Vandenberg JI; Metcalfe JC; Smith GA, 2000, 'Estimation of systolic and diastolic free intracellular Ca2+ by titration of Ca2+ buffering in the ferret heart', Biochemical Journal, vol. 346, pp. 385 - 391, http://dx.doi.org/10.1042/0264-6021:3460385
2000
Wong KR; Trezise AEO; Crozatier B; Vandenberg JI, 2000, 'Loss of the normal epicardial to endocardial gradient of cftr mRNA expression in the hypertrophied rabbit left ventricle', Biochemical and Biophysical Research Communications, vol. 278, pp. 144 - 149, http://dx.doi.org/10.1006/bbrc.2000.3754
2000
Keevil VL; Huang CLH; Chau PL; Sayeed RA; Vandenberg JI, 2000, 'The effect of heptanol on the electrical and contractile function of the isolated, perfused rabbit heart', Pflugers Archiv European Journal of Physiology, vol. 440, pp. 275 - 282, http://dx.doi.org/10.1007/s004240051049
2000
Wong KR; Trezise AEO; Vandenberg JI, 2000, 'Developmental regulation of the gradient of cftr expression in the rabbit heart', Mechanisms of Development, vol. 94, pp. 195 - 197, http://dx.doi.org/10.1016/S0925-4773(00)00312-9
2000
Wong KR; Trezise AEO; Bryant S; Hart G; Vandenberg JI, 1999, 'Molecular and functional distributions of chloride conductances in rabbit ventricle', American Journal of Physiology - Heart and Circulatory Physiology, vol. 277, http://dx.doi.org/10.1152/ajpheart.1999.277.4.h1403
1999
Wong KR; Trezise AE; Bryant S; Hart G; Vandenberg JI, 1999, 'Molecular and functional distributions of chloride conductances in rabbit ventricle.', Am J Physiol, vol. 277, pp. H1403 - H1409, http://dx.doi.org/10.1152/ajpheart.1999.277.4.H1403
1999
Wong KR; Trezise AEO; Bryant S; Hart G; Vandenberg JI, 1999, 'Molecular and functional distributions of chloride conductances in rabbit ventricle', AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, vol. 277, pp. H1403 - H1409, http://dx.doi.org/10.1152/ajpheart.1999.277.4.H1403
1999
Lowe MD; Grace AA; Vandenberg JI; Kaumann AJ, 1998, 'Action potential shortening through the putative β4-adrenoceptor in ferret ventricle: Comparison with β1- and β2-adrenoceptor-mediated effects', British Journal of Pharmacology, vol. 124, pp. 1341 - 1344, http://dx.doi.org/10.1038/sj.bjp.0702013
1998
Bethell HWL; Vandenberg JI; Smith GA; Grace AA, 1998, 'Changes in ventricular repolarization during acidosis and low-flow ischemia', AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, vol. 275, pp. H551 - H561, http://dx.doi.org/10.1152/ajpheart.1998.275.2.H551
1998
Bethell HW; Vandenberg JI; Smith GA; Grace AA, 1998, 'Changes in ventricular repolarization during acidosis and low-flow ischemia.', Am J Physiol, vol. 275, pp. H551 - H561, http://dx.doi.org/10.1152/ajpheart.1998.275.2.H551
1998
Vandenberg JI; Bett GC; Powell T, 1997, 'Contribution of a swelling-activated chloride current to changes in the cardiac action potential.', Am J Physiol, vol. 273, pp. C541 - C547, http://dx.doi.org/10.1152/ajpcell.1997.273.2.C541
1997
Vandenberg JI; Bett GCL; Powell T, 1997, 'Contribution of a swelling-activated chloride current to changes in the cardiac action potential', American Journal of Physiology - Cell Physiology, vol. 273, http://dx.doi.org/10.1152/ajpcell.1997.273.2.c541
1997
Vandenberg JI; Bett GCL; Powell T, 1997, 'Contribution of a swelling-activated chloride current to changes in the cardiac action potential', AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, vol. 273, pp. C541 - C547, http://dx.doi.org/10.1152/ajpcell.1997.273.2.C541
1997
Bethell HWL; Vandenberg JI; Grace AA, 1997, 'ATP-sensitive potassium channels and ventricular repolarisation', Heart, vol. 77
1997
Vandenberg JI; Rees SA; Wright AR; Powell T, 1996, 'Cell swelling and ion transport pathways in cardiac myocytes', CARDIOVASCULAR RESEARCH, vol. 32, pp. 85 - 97, http://dx.doi.org/10.1016/S0008-6363(96)00048-X
1996
Grace AA; Metcalfe JC; Weissberg PL; Bethell HWL; Vandenberg JI, 1996, 'Angiotensin II stimulates sodium-dependent proton extrusion in perfused ferret heart', AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, vol. 270, pp. C1687 - C1694, http://dx.doi.org/10.1152/ajpcell.1996.270.6.C1687
1996
Vandenberg JI; Carter ND; Bethell HW; Nogradi A; Ridderstråle Y; Metcalfe JC; Grace AA, 1996, 'Carbonic anhydrase and cardiac pH regulation.', Am J Physiol, vol. 271, pp. C1838 - C1846, http://dx.doi.org/10.1152/ajpcell.1996.271.6.C1838
1996
Vandenberg JI; Rees SA; Wright AR; Powell T, 1996, 'Cell swelling and ion transport pathways in cardiac myocytes', Cardiovascular Research, vol. 32, pp. 85 - 97, http://dx.doi.org/10.1016/0008-6363(96)00048-X
1996
Grace AA; Metcalfe JC; Weissberg PL; Bethell HW; Vandenberg JI, 1996, 'Angiotensin II stimulates sodium-dependent proton extrusion in perfused ferret heart.', Am J Physiol, vol. 270, pp. C1687 - C1694, http://dx.doi.org/10.1152/ajpcell.1996.270.6.C1687
1996
Vandenberg JI; Carter ND; Bethell HWL; Nogradi A; Ridderstrale Y; Metcalfe JC; Grace AA, 1996, 'Carbonic anhydrase and cardiac pH regulation', AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, vol. 271, pp. C1838 - C1846, http://dx.doi.org/10.1152/ajpcell.1996.271.6.C1838
1996
Wright AR; Rees SA; Vandenberg JI; Twist VW; Powell T, 1995, 'Extracellular osmotic pressure modulates sodium-calcium exchange in isolated guinea-pig ventricular myocytes', The Journal of Physiology, vol. 488, pp. 293 - 301
1995
Bethell HWL; Redwood SR; Vandenberg JI; Carter ND; Camm AJ; Grace AA, 1995, 'Glibenclamide and Magnesium Have Similar Effects on Repolarisation of the Cardiac Action Potential during Low-Flow Ischaemia', Clinical Science, vol. 89, pp. 32P - 33P, http://dx.doi.org/10.1042/cs089032pc
1995
Bethell HWL; Vandenberg JI; Carter ND; Grace AA, 1995, 'Differential Effects of Intracellular and Extracellular Acidosis on Cardiac Action Potential Repolarisation', Clinical Science, vol. 89, pp. 20P - 20P, http://dx.doi.org/10.1042/cs089020p
1995
Rees SA; Vandenberg JI; Wright AR; Yoshida A; Powell T, 1995, 'Cell swelling has differential effects on the rapid and slow components of delayed rectifier potassium current in guinea pig cardiac myocytes', The Journal of General Physiology, vol. 106, pp. 1151 - 1170, http://dx.doi.org/10.1085/jgp.106.6.1151
1995
Vandenberg JI; Yoshida A; Kirk K; Powell T, 1994, 'Swelling-activated and isoprenaline-activated chloride currents in guinea pig cardiac myocytes have distinct electrophysiology and pharmacology', Journal of General Physiology, vol. 104, pp. 997 - 1017, http://dx.doi.org/10.1085/jgp.104.6.997
1994
Vandenberg JI; Metcalfe JC; Grace AA, 1994, 'Intracellular pH recovery during respiratory acidosis in perfused hearts', AM.J.PHYSIOL., vol. 266
1994
Vandenberg JI; Metcalfe JC; Grace AA, 1994, 'Intracellular pH recovery during respiratory acidosis in perfused hearts', American Journal of Physiology - Cell Physiology, vol. 266, http://dx.doi.org/10.1152/ajpcell.1994.266.2.c489
1994
Vandenberg JI; Metcalfe JC; Grace AA, 1994, 'Intracellular pH recovery during respiratory acidosis in perfused hearts.', Am J Physiol, vol. 266, pp. C489 - C497, http://dx.doi.org/10.1152/ajpcell.1994.266.2.C489
1994
Bethell HWL; Vandenberg JI; Grace AA, 1994, 'Prolongation of the Monophasic Action Potential Duration during Acidosis and Shortening during Low-Flow Ischaemia', Clinical Science, vol. 86, pp. 19P - 19P, http://dx.doi.org/10.1042/cs086019pa
1994
VANDENBERG JI; METCALFE JC; GRACE AA, 1994, 'INTRACELLULAR PH RECOVERY DURING RESPIRATORY-ACIDOSIS IN PERFUSED HEARTS', AMERICAN JOURNAL OF PHYSIOLOGY, vol. 266, pp. C489 - C497, http://dx.doi.org/10.1152/ajpcell.1994.266.2.C489
1994
Bethell H; Vandenberg JI; Crowley J; Grace AA, 1994, 'Glibenclamide Increases Action Potential Duration with Partial Inhibition of Rubidium Efflux during Early Myocardial Ischaemia', Clinical Science, vol. 87, pp. 5P - 5P, http://dx.doi.org/10.1042/cs045005pa_pt2
1994
Grace AA; Kirschenlohr HL; Metcalfe JC; Smith GA; Weissberg PL; Cragoe EJ; Vandenberg JI, 1993, 'Regulation of intracellular pH in the perfused heart by external HCO3/- and Na+-H+ exchange', American Journal of Physiology - Heart and Circulatory Physiology, vol. 265, http://dx.doi.org/10.1152/ajpheart.1993.265.1.h289
1993
Grace AA; Metcalfe JC; Weissberg PL; Vandenberg JI, 1993, 'Na+-H+ Antiport and Na+/HCO3− Co-Influx in Recovery from Intracellular Acidosis in Perfused Heart', Clinical Science, vol. 84, pp. 15P - 16P, http://dx.doi.org/10.1042/cs084015pc
1993
Grace AA; Metcalfe JC; Weissberg PL; Vandenberg JI, 1993, 'Angiotensin II Stimulates Acid Extrusion in Heart', Clinical Science, vol. 84, pp. 15P - 15P, http://dx.doi.org/10.1042/cs084015pb
1993
Grace AA; Metcalfe JC; Weissberg PL; Vandenberg JI, 1993, 'Dissociation between Recovery of pHi and Contraction Following Acid Loading in Perfused Heart', Clinical Science, vol. 84, pp. 15P - 15P, http://dx.doi.org/10.1042/cs084015pa
1993
Vandenberg JI; Metcalfe JC; Grace AA, 1993, 'Mechanisms of pH(i) recovery after global ischemia in the perfused heart', Circulation Research, vol. 72, pp. 993 - 1003, http://dx.doi.org/10.1161/01.res.72.5.993
1993
GRACE AA; KIRSCHENLOHR HL; METCALFE JC; SMITH GA; WEISSBERG PL; CRAGOE EJ; VANDENBERG JI, 1993, 'REGULATION OF INTRACELLULAR PH IN THE PERFUSED HEART BY EXTERNAL HCO3- AND NA+-H+ EXCHANGE', AMERICAN JOURNAL OF PHYSIOLOGY, vol. 265, pp. H289 - H298, http://dx.doi.org/10.1152/ajpheart.1993.265.1.H289
1993
Vandenberg JI; Metcalfe JC; Grace AA, 1992, 'Mechanisms of intracellular pH recovery following global ischaemia in the perfused ferret heart', Journal of Molecular and Cellular Cardiology, vol. 24, pp. 116 - 116, http://dx.doi.org/10.1016/0022-2828(92)90374-9
1992
Vandenberg JI; Metcaffe JC; Grace AA, 1992, 'Mechanisms of pHi recovery from intracellular acidosis in perfused ferret heart', Journal of Molecular and Cellular Cardiology, vol. 24, pp. 137 - 137, http://dx.doi.org/10.1016/0022-2828(92)90436-4
1992
Heitmann S; Vandenberg JI; Hill AP, 'Arrhythmogenesis as the failure of repolarization', , http://dx.doi.org/10.1101/2020.07.02.185694
Conference Abstracts
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Flood E; Lau C; Hunter M; Ng C-A; Perozo E; Allen TW; Vandenberg JI, 2021, 'Investigation of the Inactivation of HERG using Molecular Dynamics Simulations of New cryo-EM Structures', in BIOPHYSICAL JOURNAL, CELL PRESS, Vol. 120, pp. 242A - 242A, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000629601401425&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2021
Jiang C; Farr J; Hill A; Kroncke B; Ingles J; Vandenberg J; Ng CA, 2021, 'Abstract 11857: Benchmarking a Functional Assay to Assist Clinical Classification of Variants of Uncertain Significance in KCNH2 (Long QT Syndrome Type 2)', in Circulation, Ovid Technologies (Wolters Kluwer Health), Vol. 144, http://dx.doi.org/10.1161/circ.144.suppl_1.11857
2021
Ullah R; Ng C; Farr J; Hill A; kozek K; Vanags L; Mitchell D; Vandenberg J; Kroncke B, 2021, 'Abstract 11153: Massively Parallel, High-Throughput Approach for Identifying Defective KCNH2 (hERG) Variants', in Circulation, Ovid Technologies (Wolters Kluwer Health), Vol. 144, http://dx.doi.org/10.1161/circ.144.suppl_1.11153
2021
Beattie KA; Bardenet R; Louttit JB; Vandenberg JI; Hill AP; Gavaghan DJ; de Boer TP; Mirams GR, 2017, 'Mathematical Modelling of hERG Channel Kinetics Using Sinusoidal Voltage Protocols', in JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS, ELSEVIER SCIENCE INC, Vol. 88, pp. 195 - 196, http://dx.doi.org/10.1016/j.vascn.2017.09.089
2017
Mann SA; Vandenberg JI; Hill AP, 2016, 'Sudden Infant Death and Modulation of Late Sodium Current by Hypoxia, Investigated in Induced Pluripotent Stem Cells', in BIOPHYSICAL JOURNAL, CELL PRESS, Los Angeles, CA, Vol. 110, pp. 30A - 30A, presented at 60th Annual Meeting of the Biophysical-Society, Los Angeles, CA, 27 February 2016 - 02 March 2016, http://dx.doi.org/10.1016/j.bpj.2015.11.227
2016
Hill AP; Mann SA; Imtiaz MS; Perry MD; Vandenberg JI, 2014, 'Using Clinical Datasets to Optimize Models of Human Ventricular Electrophysiology: Implications for In Silico Drug Screening', in BIOPHYSICAL JOURNAL, CELL PRESS, San Francisco, CA, Vol. 112, pp. 465A - 465A, presented at 58th Annual Meeting of the Biophysical-Society, San Francisco, CA, 15 February 2014 - 19 February 2014, http://dx.doi.org/10.1016/j.bpj.2016.11.2493
2014
Mann SA; Vandenberg JI, 2014, 'Dynamic Action Potential Clamp Investigation of Pro-Arrhythmic Risk of Drugs Binding to hERG Potassium Channels', in BIOPHYSICAL JOURNAL, CELL PRESS, San Francisco, CA, Vol. 106, pp. 553A - 553A, presented at 58th Annual Meeting of the Biophysical-Society, San Francisco, CA, 15 February 2014 - 19 February 2014, http://dx.doi.org/10.1016/j.bpj.2013.11.3075
2014
El-Ajouz S; Hill AP; Gulbis JM; Vandenberg JI, 2013, 'Understanding the Molecular Gates of KirBac3.1', in BIOPHYSICAL JOURNAL, CELL PRESS, Philadelphia, PA, Vol. 104, pp. 128A - 128A, presented at 57th Annual Meeting of the Biophysical-Society, Philadelphia, PA, 02 February 2013 - 06 February 2013, http://dx.doi.org/10.1016/j.bpj.2012.11.737
2013
Olesen M; Liang B; Soka M; Larsen AP; Knop FK; Wang F; Nielsen JB; Andersen MN; Humphreys D; Mann SA; Vandenberg JI; Svendsen JH; Haunso S; Preiss T; Seebohm G; Olesen S-P; Schmitt N; Fatkin D, 2013, 'TASK-1 potassium channel mutations in atrial fibrillation', in EUROPEAN HEART JOURNAL, OXFORD UNIV PRESS, Amsterdam, NETHERLANDS, Vol. 34, pp. 642 - 642, presented at Congress of the European-Society-of-Cardiology (ESC), Amsterdam, NETHERLANDS, 31 August 2013 - 04 September 2013, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000327744604084&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2013
Ke Y; Hunter M; Ng CA; Vandenberg J, 2012, 'Domain Misfolding and Destabilisation of Domain–Domain Interactions Both Contribute to Defective Trafficking of hERG EAG Domain Mutant Channels', in Heart, Lung and Circulation, Vol. 21, pp. 860 - 861, http://dx.doi.org/10.1016/j.hlc.2012.08.025
2012
Tan PS; Perry M; Chai AN; Vandenberg JI; Hill AP, 2012, 'Bimodal Regulation of hERG Gating by the N-Terminal Tail Revealed by Voltage Clamp Fluorometry', in BIOPHYSICAL JOURNAL, CELL PRESS, San Diego, CA, Vol. 102, pp. 328A - 328A, presented at 56th Annual Meeting of the Biophysical-Society, San Diego, CA, 25 February 2012 - 29 February 2012, http://dx.doi.org/10.1016/j.bpj.2011.11.1800
2012
Perry MD; Vandenberg JI, 2012, 'Critical Dual Role for the Pore Helix in Kv11.1 Channel Inactivation', in BIOPHYSICAL JOURNAL, CELL PRESS, San Diego, CA, Vol. 102, pp. 328A - 328A, presented at 56th Annual Meeting of the Biophysical-Society, San Diego, CA, 25 February 2012 - 29 February 2012, http://dx.doi.org/10.1016/j.bpj.2011.11.1801
2012
Szekely D; Dokos S; Vandenberg JI; Hill AP, 2010, 'An Improved Curvilinear Gradient Method for Parameter Estimation in Complex Model Systems: Application to Gating of A Cardiac Ion Channel', in BIOPHYSICAL JOURNAL, CELL PRESS, Vol. 98, pp. 140A - 141A, http://dx.doi.org/10.1016/j.bpj.2009.12.758
2010
Heide J; Mann SA; Vandenberg JI, 2010, 'CHARACTERIZATION OF A NOVEL HERG POTASSIUM CHANNEL ISOFORM UPREGULATED IN SCHIZOPHRENIA PATIENTS', in AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY, INFORMA HEALTHCARE, Vol. 44, pp. A51 - A51, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000282954700142&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2010
Mann SA; Hill A; Vandenberg JI, 2009, 'Investigating Ion Channel Diseases With Dynamic Action Potential Clamp', in BIOPHYSICAL JOURNAL, CELL PRESS, Vol. 96, pp. 259A - 259A, http://dx.doi.org/10.1016/j.bpj.2008.12.1279
2009
Ju P; Torres A; Bansal PS; Vandenberg JI; Kuchel PW, 2007, 'Pore helix domain charged residues modulate inactivation of the hERG K+ channel', in Biophysical Journal, Biophysical Society, Baltimore, MD, pp. 123A - 123A, presented at 51st Annual Meeting of the Biophysical-Society, Baltimore, MD, 03 - 07 March 2007, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000243972400567&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
2007
Subbiah RN; Campbell TJ; Vandenberg JI, 2005, 'Tryptophan scanning mutagenesis suggests that the voltage sensor in HERG has a peripheral location', in Heart Rhythm, Vol. 2, pp. S106 - S107, http://www.sciencedirect.com/science/article/B7GW9-4GCD5P7-5/2/a4c7846becaa57ceeccffc5c4337c1ab
2005
Clarke CE; Bursill JA; Zhao J; Wyse KR; Vandenberg JI, 2004, 'Sensitivity of human ether-a-go-go family channels to extracellulartetraethylammonium', in Biophysical Journal, Biophysical Society, Vol. 86, pp. 278A - 278A
2004
Subbiah RN; Clarke CE; Smith DG; Zhao J; Vandenberg JI; Campbell TJ, 2004, 'Alteration of voltage-dependence and activation kinetics of the HERGpotassium channel by mutations in the S4 sequence', in Biophysical Journal, Biophysical Society, Baltimore, MD, Vol. 86, pp. 541A - 541A, presented at 48th Annual Meeting of the Biophysical Society, Baltimore, MD, 14 - 18 February 2004, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000187971202791&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
2004
Saumarez RC; Vandenberg JI; Zinkin MP; Lowe MD; Taylor PJ; Ward DE; Camm AJ; Grace AA, 1997, 'Electrogram fractionation in the long QT syndrome and as modelled in perfused heart by inhibition of SCN5A-encoded ion channels', in Heart, Vol. 77
1997
Phan K; Ng C; McNitt S; Moss A; Zareba W; Perry M; Vandenberg J, 'The role of in vitro phenotypes for clinical risk stratification of sudden death in Long QT Syndrome Type 2', in Heart, Lung and Circulation, Elsevier, Vol. 24, pp. S232 - S233, presented at Heart, Lung and Circulation, http://dx.doi.org/10.1016/j.hlc.2015.06.289
Other
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Ng C-A; Ullah R; Farr J; Hill A; Kozek K; Vanags L; Mitchell D; Kroncke B; Vandenberg J, 2021, A Massively Parallel Trafficking Assay Accurately Predicts Loss of Channel Function in KCNH2 Variants, Cold Spring Harbor Laboratory, http://dx.doi.org/10.1101/2021.07.10.451881
2021
Vandenberg JI; Hill AP, 2016, An 'alternans' way to quantify arrhythmogenic substrates, http://dx.doi.org/10.1113/JP271838
2016
Martinac B; Vandenberg J, 2015, 'Shooting gallery' for membrane proteins provides new insights into complexities of their function and structural dynamics, http://dx.doi.org/10.1113/jphysiol.2014.286559
2015
Vandenberg JI, 2010, Oxidative stress fine-tunes the dance of hERG K+ channels, Blackwell Publishing Ltd, http://dx.doi.org/10.1113/jphysiol.2010.195651
2010
Vandenberg JI; Hill AP; Campbell TJ; Clarke CE, 2006, Reply from Jamie I. Vandenberg, Adam P. Hill, Terence J. Campbell, Catherine E. Clarke [2], http://dx.doi.org/10.1113/jphysiol.2006.577102
2006
Subbiah RN; Campbell TJ; Vandenberg JI, 2005, Erratum: Inherited cardiac arrhythmia syndromes: What have they taught us about arrhythmias and anti-arrhythmic therapy? (Clinical and Experimental Pharmacology and Physiology (2004) 31 (906-912))
2005
Preprints
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Jiang C; Richardson E; Farr J; Hill A; Ullah R; Kroncke B; Harrison S; Thomson K; Ingles J; Vandenberg J; Ng C-A, 2021, A calibrated functional patch clamp assay to enhance clinical variant interpretation in KCNH2-related long QT syndrome, http://dx.doi.org/10.1101/2021.12.13.472492
2021
Vandenberg J; Lau C; Flood E; Hunter M; Ng C-A; Bouwer J; Stewart A; Perozo E; Allen T, 2021, Structural Basis for Rapid Voltage Dependent Inactivation of HERG Potassium Channels, http://dx.doi.org/10.21203/rs.3.rs-1105661/v1
2021
Kozek KA; Glazer AM; Ng C-A; Blackwell D; Egly CL; Vanags LR; Blair M; Mitchell D; Matreyek KA; Fowler DM; Knollmann BC; Vandenberg J; Roden DM; Kroncke BM, High-throughput discovery of trafficking-deficient variants in the cardiac potassium channel KCNH2: Deep mutational scan of KCNH2 trafficking, http://dx.doi.org/10.1101/2020.02.17.952606
Lee W; Windley MJ; Perry MD; Vandenberg JI; Hill AP, Protocol-dependent differences in IC50 values measured in hERG assays occur in a predictable way and can be used to quantify state preference of drug binding, http://dx.doi.org/10.1101/534867
Windley MJ; Farr J; Vandenberg JI; Hill AP, Translating the Measurement of Herg Kinetics and Drug Block for Cipa to a High Throughput Platform, http://dx.doi.org/10.2139/ssrn.4065593
Working Papers
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Ballouz S; Mangala M; Perry M; Heitmann S; Gillis J; Hill A; Vandenberg J, 2019, Co-expression of calcium channels and delayed rectifier potassium channels protects the heart from proarrhythmic events, http://dx.doi.org10.1101/659821
2019
Beattie K; Hill A; Bardenet R; Cui Y; Vandenberg J; Gavaghan D; de Boer T; Mirams G, 2017, Sinusoidal voltage protocols for rapid characterisation of ion channel kinetics, Cold Spring Harbor Laboratory, http://dx.doi.org10.1101/100677
2017
Hodkinson EC; Hill AP; Vandenberg JI, 2014, The romano-ward syndrome 1964 2014: 50 years of progress, http://dx.doi.org
2014
Conference Papers
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Windley M; Mann S; Vandenberg J; Hill A, 2017, 'Temperature Effects on Kinetics of hERG Drug Block: Implications for In Silico Proarrhythmic Risk Prediction', in JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS, ELSEVIER SCIENCE INC, pp. 203 - 203, http://dx.doi.org/10.1016/j.vascn.2017.09.116
2017
Windley M; Abi-Gerges N; Fermini B; Hancox J; Vandenberg J; Hill A, 2017, 'Successes and Challenges of Performing hERG Studies for CiPA', in JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS, ELSEVIER SCIENCE INC, pp. 197 - 197, http://dx.doi.org/10.1016/j.vascn.2017.09.095
2017
Vandenberg JI; Conigrave A; King GF; Kirk K, 2013, 'From kinetics to imaging: an NMR odyssey--a festschrift symposium in honour of Philip William Kuchel.', in Eur Biophys J, Germany, pp. 1 - 2, Germany, http://dx.doi.org/10.1007/s00249-012-0883-8
2013
Vandenberg JI; Kuchel PW, 2010, 'Proteins, membranes and cells: the structure-function nexus', in European Biophysics Journal, Springer, pp. 1 - 1, http://dx.doi.org/10.1007/s00249-009-0535-9
2010
Hill AP; Varghese A; Dokos S; Mann S; Vandenberg JI, 2009, 'Developing In Silico Descriptions Of Herg Channel Gating', in BIOPHYSICAL JOURNAL, CELL PRESS, pp. 191A - 191A, http://dx.doi.org/10.1016/j.bpj.2008.12.897
2009
Otway RT; Vandenberg JI; Guo G; Fatkin D, 2007, 'Interaction between a KCNQ1 mutation and cell stretch in familial atrial fibrillation', in BIOPHYSICAL JOURNAL, BIOPHYSICAL SOCIETY, Baltimore, MD, pp. 463A - 463A, presented at 51st Annual Meeting of the Biophysical-Society, Baltimore, MD, 03 March 2007 - 07 March 2007, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000243972403011&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2007
Vandenberg JI; Bansal PS; Torres AM; Kuchel PW; Alewood PA, 2005, 'Molecular basis of CnErg1 binding to HERG K+ channels', in JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD, Bristol Univ, Bristol, ENGLAND, pp. 172 - 173, presented at 4th Mammalian Myocardium Meeting, Bristol Univ, Bristol, ENGLAND, 17 July 2005 - 20 July 2005, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000230435000030&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2005
Varghese A; Lu Y; Smith MM; Huang CLH; Vandenberg JI, 2003, 'Temperature dependence of HERG inactivation', in BIOPHYSICAL JOURNAL, BIOPHYSICAL SOCIETY, SAN ANTONIO, TEXAS, pp. 544A - 544A, presented at 47th Annual Meeting of the Biophysical-Society, SAN ANTONIO, TEXAS, 01 March 2003 - 05 March 2003, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000183123802674&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2003
Fahmi AI; Vandenberg J, 2002, 'The sodium channel beta subunit, SCN3b, increases the expression levels of SCN5a and is heterogeneously expressed in sheep cardiac tissue', in BIOPHYSICAL JOURNAL, BIOPHYSICAL SOCIETY, pp. 91A - 91A, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000173252700447&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2002
Wallerstein PMR; Vandenberg JI; Huang CLH; Saumarez RC; Grace AA, 2001, 'Intraventricular conduction delay, electrogram fractionation and arrhythmias in the KCNE1 mutant mouse', in BIOPHYSICAL JOURNAL, BIOPHYSICAL SOCIETY, pp. 644A - 645A, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000166692202930&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2001
Varghese A; Lu Y; Huang CLH; Mahaut-Smith MP; Vandenberg JI, 2001, 'Modeling the effects of premature stimuli on HERG K+ channels', in BIOPHYSICAL JOURNAL, BIOPHYSICAL SOCIETY, pp. 638A - 638A, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000166692202903&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2001
Lu Y; Mahaut-Smith MP; Huang CLH; Vandenberg JI, 2001, 'Effects of temperature on HERG K+ channel response to premature stimuli', in BIOPHYSICAL JOURNAL, BIOPHYSICAL SOCIETY, pp. 213A - 213A, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000166692200975&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2001
Lu Y; Mahaut-Smith MP; Huang CLH; Vandenberg JI, 2000, 'MiRP1 alters activation of HERG K+ channels stably transfected in a mammalian cell line', in JOURNAL OF PHYSIOLOGY-LONDON, CAMBRIDGE UNIV PRESS, pp. 120P - 120P, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000089787600154&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2000
Lu Y; Mahaut-Smith MP; Huang CLH; Kemp PR; Vandenberg JI, 2000, 'Effects of premature stimuli on HERG-encoded K+ currents under action potential clamp conditions', in JOURNAL OF PHYSIOLOGY-LONDON, CAMBRIDGE UNIV PRESS, pp. 93P - 94P, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000088237300117&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2000
Furness RB; Fowden AL; Forhead AJ; Vandenberg JI, 2000, 'Developmental regulation of cardiac erg potassium channel mRNA expression in fetal sheep during late gestation', in JOURNAL OF PHYSIOLOGY-LONDON, CAMBRIDGE UNIV PRESS, pp. 66P - 66P, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000089787600081&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2000
Paul LEA; Huang CL; Grace AA; Saumarez RC; Vandenberg JI, 1999, 'Analysis of Purkinje system contributions to conduction in the perfused heart', in BIOPHYSICAL JOURNAL, BIOPHYSICAL SOCIETY, pp. A85 - A85, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000081085900490&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
1999
Lowe MD; Grace AA; Vandenberg JI; Kaumann AJ, 1998, 'Electrophysiological effects mediated through the putative beta 4-adrenoceptor', in CIRCULATION, LIPPINCOTT WILLIAMS & WILKINS, pp. 491 - 491, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000076594402610&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
1998
Lowe MD; Grace AA; Vandenberg JI; Kaumann AJ, 1998, 'Electrophysiological effects mediated through the putative beta(4)-adrenoceptor in ventricular myocardium', in NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, SPRINGER VERLAG, pp. R623 - R623, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000075207800947&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
1998
Smith GA; Kirschenlohr HL; Grace AA; Metcalfe JC; Vandenberg JI, 1997, 'Buffering of the cardiac calcium transient by exogenous calcium indicators', in JOURNAL OF PHYSIOLOGY-LONDON, CAMBRIDGE UNIV PRESS, pp. P132 - P132, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1997XD09100189&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
1997
Vandenberg JI; Grace AA; Zinkin MP; Lowe MD; Saumarez RC, 1997, 'Anthopleurin A causes cardiac electrogram fractionation following premature stimulation.', in BIOPHYSICAL JOURNAL, CELL PRESS, pp. MP129 - MP129, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1997WE74700264&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
1997
Trezise AEO; Wong KR; Vandenberg JI, 1997, 'Distribution of cftr mRNA in rabbit left ventricular myocardium.', in JOURNAL OF PHYSIOLOGY-LONDON, CAMBRIDGE UNIV PRESS, pp. P74 - P75, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1997YJ42400087&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
1997
Wright AR; Rees SA; Vandenberg JI; Twist VW; Powell T, 1996, 'Simultaneous recording of Na+/Ca2+ exchange current and swelling activated Cl- current from isolated guinea-pig atrial myocytes', in BIOPHYSICAL JOURNAL, CELL PRESS, pp. MP287 - MP287, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1996TZ68201170&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
1996
Bethell HW; Vandenberg JI; Smith GA; Grace AA, 1996, 'Ischemic potassium flux is driven by an early net inward current', in CIRCULATION, AMER HEART ASSOC, pp. 3081 - 3081, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1996VN11903073&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
1996
VANDENBERG JI; REES SA; TWIST VW; WRIGHT AR; POWELL T, 1995, 'A SWELLING-ACTIVATED CHLORIDE CONDUCTANCE CONTRIBUTES TO ACTION-POTENTIAL SHORTENING IN GUINEA-PIG VENTRICULAR MYOCYTES DURING CELL SWELLING', in CIRCULATION, AMER HEART ASSOC, pp. 3059 - 3059, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1995TB48003039&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
1995
HALL JA; KIRK J; POTTS JR; RAE CD; VANDENBERG JI; KIRK K, 1995, 'SWELLING-ACTIVATED TRANSPORT OF DIVERSE SOLUTES IN A HUMAN CANCER CELL-LINE', in JOURNAL OF PHYSIOLOGY-LONDON, CAMBRIDGE UNIV PRESS, pp. P96 - P96, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1995TB77500148&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
1995
BETHELL HWL; VANDENBERG JI; GRACE AA, 1994, 'PROLONGATION OF THE MONOPHASIC ACTION-POTENTIAL DURING ACIDOSIS AND SHORTENING DURING ISCHEMIA', in JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, ELSEVIER SCIENCE INC, pp. A46 - A46, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1994PP51800176&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
1994
REDWOOD S; BETHELL HWL; VANDENBERG JI; CAMM AJ; GRACE AA, 1994, 'MAGNESIUM HAS CONCENTRATION AND TIME-DEPENDENT EFFECTS ON ACTION-POTENTIAL DURATION DURING MYOCARDIAL-ISCHEMIA', in CIRCULATION, AMER HEART ASSOC, pp. 524 - 524, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1994PN41702852&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
1994
VANDENBERG JI; YOSHIDA A; KIRK K; TWIST VW; POWELL T, 1994, 'CELL SWELLING ACTIVATES A CHLORIDE CURRENT IN GUINEA-PIG VENTRICULAR MYOCYTES', in JOURNAL OF PHYSIOLOGY-LONDON, CAMBRIDGE UNIV PRESS, pp. P83 - P83, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1994NA54100147&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
1994
REES SA; YOSHIDA A; TWIST VW; VANDENBERG JI; POWELL T, 1994, 'SWELLING ACTIVATED DELAYED RECTIFIER POTASSIUM CURRENT IN GUINEA-PIG VENTRICULAR MYOCYTES', in HEART AND VESSELS, SPRINGER VERLAG, TOKYO, JAPAN, pp. 145 - 146, presented at Tokyo-Womens-Medical-College International Symposium 94 - Ion Channels and Cellular Function of the Heart: Molecular Mechanisms Underlying the Regulation of Cardiac Cellular Function, TOKYO, JAPAN, 08 July 1994 - 10 July 1994, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1995RA84700047&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
1994
VANDENBERG JI; YOSHIDA A; KIRK K; POWELL T, 1994, 'SWELLING-ACTIVATED CHLORIDE CURRENTS IN GUINEA-PIG CARDIAC MYOCYTES', in HEART AND VESSELS, SPRINGER VERLAG, TOKYO, JAPAN, pp. 144 - 144, presented at Tokyo-Womens-Medical-College International Symposium 94 - Ion Channels and Cellular Function of the Heart: Molecular Mechanisms Underlying the Regulation of Cardiac Cellular Function, TOKYO, JAPAN, 08 July 1994 - 10 July 1994, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1995RA84700046&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
1994
VANDENBERG JI; CARTER ND; GRACE AA, 1993, 'SARCOLEMMAL CARBONIC-ANHYDRASE AND REGULATION OF CARDIAC PH', in CIRCULATION, AMER HEART ASSOC, pp. 39 - 39, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1993MA68200239&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
1993
VANDENBERG JI; METCALFE JC; GRACE AA, 1993, 'THE RECOVERY OF INTRACELLULAR PH DURING RESPIRATORY-ACIDOSIS IN THE ISOLATED PERFUSED FERRET HEART', in JOURNAL OF PHYSIOLOGY-LONDON, CAMBRIDGE UNIV PRESS, pp. P414 - P414, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1993KG43100410&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
1993
GRACE AA; METCALFE JC; WEISSBERG PL; VANDENBERG JI, 1993, 'ANGIOTENSIN-II STIMULATES ACID EXTRUSION IN ISOLATED PERFUSED FERRET HEART', in JOURNAL OF PHYSIOLOGY-LONDON, CAMBRIDGE UNIV PRESS, pp. P415 - P415, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1993KG43100411&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
1993
GRACE AA; METCALFE JC; BETHELL HW; VANDENBERG JI, 1993, 'ANGIOTENSIN-II STIMULATES PROTON EXTRUSION DURING REPERFUSION', in CIRCULATION, AMER HEART ASSOC, pp. 430 - 430, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1993MA68202344&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
1993
GRACE AA; VANDENBERG JI, 1993, 'ANGIOTENSIN-II ENHANCES CARDIAC PHI REGULATION IN THE PRESENCE OF HCO3- VIA 3 ACID-BASE TRANSPORT MECHANISMS', in CIRCULATION, AMER HEART ASSOC, pp. 331 - 331, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1993MA68201813&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
1993
VANDENBERG JI; METCALFE JC; GRACE AA, 1992, 'CONTRIBUTION OF LACTATE EFFLUX TO PHI RECOVERY FOLLOWING GLOBAL-ISCHEMIA IN THE PERFUSED FERRET HEART', in JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD, pp. S54 - S54, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1992JJ55600084&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
1992
GRACE AA; METCALFE JC; WEISSBERG PL; VANDENBERG JI, 1992, 'RELATIVE CONTRIBUTION OF THE NA+-H+ ANTIPORT AND HCO3--DEPENDENT MECHANISMS TO PROTON EFFLUX DURING INTRACELLULAR ACIDOSIS IN PERFUSED HEART', in JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD, pp. S54 - S54, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1992JJ55600082&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
1992
GRACE AA; KIRSCHENLOHR HL; SMITH GA; METCALFE JC; WEISSBERG PL; VANDENBERG JI, 1992, 'HCO3--DEPENDENCE OF RECOVERY FROM INTRACELLULAR ACIDOSIS IN THE PERFUSED FERRET HEART DURING NA+-H+ ANTIPORT INHIBITION', in JOURNAL OF PHYSIOLOGY-LONDON, CAMBRIDGE UNIV PRESS, pp. P141 - P141, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1992HD60500136&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
1992
VANDENBERG JI; METCALFE JC; GRACE AA, 1992, 'MECHANISMS OF INTRACELLULAR PH RECOVERY FOLLOWING GLOBAL-ISCHEMIA IN THE PERFUSED HEART', in CIRCULATION, AMER HEART ASSOC, pp. S9 - S9, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1992JT66000023&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
1992
Grace AA; Kirschenlohr HL; Smith GA; Metcalfe JC; Weissberg PL; Vandenberg JI, 1992, 'HCO3--dependence of recovery from intracellular acidosis in the perfused ferret heart during Na+-H+ antiport inhibition', in Journal of Physiology
1992
HOEIJMAKERS HWM; VANDENBERG JI, 1991, 'APPLICATION OF AN EULER-EQUATION METHOD TO A SHARP-EDGED DELTA-WING CONFIGURATION WITH VORTEX FLOW', in COLLECTION OF TECHNICAL PAPERS - AIAA 9TH APPLIED AERODYNAMICS CONFERENCE, VOLS 1 AND 2, AMER INST AERONAUTICS & ASTRONAUTICS, BALTIMORE, MD, pp. 838 - 850, presented at 9TH APPLIED AERODYNAMICS CONF, BALTIMORE, MD, 23 September 1991 - 25 September 1991, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:A1991BW68G00020&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
1991
Datasets
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Vandenberg J; Ng CA, 2016, Faculty Opinions recommendation of Tetrameric Assembly of K+ Channels Requires ER-Located Chaperone Proteins., http://dx.doi.org/10.3410/f.727072588.793526218
2016
Book Chapters
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Vandenberg JI; Ng CA; Mann SA; Perry MD, 2014, 'Voltage-Gated Potassium Channels (Kv10-Kv12)', in Reference Module in Biomedical Research, http://dx.doi.org/10.1016/B978-0-12-801238-3.04809-1
2014
Grace AA; Saumarez RC; Vandenberg JI, 1999, 'Genetic Engineering and Cardiac Ion Channels', in Developments in Cardiovascular Medicine, Springer Netherlands, pp. 171 - 178, http://dx.doi.org/10.1007/978-94-015-9321-2_16
1999
Conference Proceedings (Editor of)
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2012, 'BIOPHYSCHEM2011: A joint meeting of the Australian society for biophysics and the RACI physical chemistry division', C S I R O Publishing, Vol. 65, pp. 439 - 441, http://dx.doi.org/10.1071/CH12213
2012
2009, 'Proteins, membranes and cells: the structure-function nexus-ASB 2008.', Vol. 39, pp. 1
2009

Awards

1992         International Society of Heart Research Young Investigator Travel Award

1992         American Heart Association Melvyn L. Marcus Young Investigator Award in Integrated Physiology (finalist)

1994         Gedge Prize (for best research undertaken by a student in Physiological Sciences) at University of Cambridge

2014         National Lecturer (Australian Physiological Society)

2015         Sir Bob Robertson Award (Australian Society for Biophysics)

2015         Elected Fellow of the Heart Rhythm Society, USA

2015         Elected Fellow, Australian Academy of Health and Medical Sciences

2018         Elected Fellow, International Society of Heart Research

 

Scholarships and Fellowships

1984         AMSA-AMA B.Sc.(Med.) Scholarship

1990-91   Sir Robert Menzies Memorial Scholarship in Medicine

1990-92   Overseas Research Scholar Award - Department of Education, UK

1992-93   Sydney University Medical Foundation Sir Zelman Cowan Traveling Research Fellowship 

1993-95   Zeneca Junior Research Fellowship, Pembroke College, Oxford, UK

1996-01   British Heart Foundation Basic Science Award

1996-01   British Heart Foundation Basic Science Award (resigned December 2001)

2002-06   NHMRC RD Wright Career Development Award in Biomedical Science

2007-11   NHMRC Senior Research Fellowship Level A

2012-16   NHMRC Senior Research Fellowship Level B with SEO (translation)

2017-21   NHMRC Principal Research Fellowship with SEO (translation)

Current Research Grants

NHMRC Principal Research Fellowship (2017-2021) Vandenberg JI $838,875

NHMRC Program Grant (2015-2019). Finding new evidence based therapies for treating heart disease and stimulating Regeneration. RP Harvey, RM Graham, PS Macdonald, D Fatkin, SL Dunwoodie, JI Vandenberg $10,600,000

NHMRC Project Grant (2018-2020). The structural basis for promiscuity of drug binding to hERG K+ channels. JI Vandenberg, AG Stewart TW Allen, E Perozo $713,035

 

Sudden Cardiac Death

Cardiac Arrhythmias

Molecular basis of cardiac electrical activity

anti-arrhythmic drugs

Drug induced cardiac arrhythmias

School of Medical Sciences, Cardiovascular Physiology, Yr3: Cardiac Arrhythmias

Medicine Yr3: Anti-arrhythmic drugs