Hatem Alkhouri

ECI Research Fellow
Visiting Fellow

publications

Journal articles
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Ghedina N; Alkhouri H; Badge H; Fogg T; McCarthy S, 2019, 'Paediatric intubation in Australasian emergency departments: A report from the ANZEDAR', EMA - Emergency Medicine Australasia, http://dx.doi.org/10.1111/1742-6723.13416
2019
Alkhouri H; Maka K; Wong L; McCarthy S, 2019, 'Impact of the primary contact physiotherapy practitioner role on emergency department care for patients with musculoskeletal injuries in New South Wales', EMA - Emergency Medicine Australasia, http://dx.doi.org/10.1111/1742-6723.13391
2019
Lewis ET; Dent E; Alkhouri H; Kellett J; Williamson M; Asha S; Holdgate A; Mackenzie J; Winoto L; Fajardo-Pulido D; Ticehurst M; Hillman K; McCarthy S; Elcombe E; Rogers K; Cardona M, 2019, 'Which frailty scale for patients admitted via Emergency Department? A cohort study', Archives of Gerontology and Geriatrics, vol. 80, pp. 104 - 114, http://dx.doi.org/10.1016/j.archger.2018.11.002
2019
Mane G; Alkhouri H; Dinh M; McCarthy S, 2019, 'One hundred and counting: Centenarian use of emergency departments in New South Wales', EMA - Emergency Medicine Australasia, vol. 31, pp. 626 - 631, http://dx.doi.org/10.1111/1742-6723.13259
2019
Ferguson I; Alkhouri H; Fogg T; Aneman A, 2019, 'Ketamine use for rapid sequence intubation in Australian and New Zealand emergency departments from 2010 to 2015: A registry study', EMA - Emergency Medicine Australasia, vol. 31, pp. 205 - 210, http://dx.doi.org/10.1111/1742-6723.13114
2019
Cardona M; Lewis ET; Turner RM; Alkhouri H; Hillman K, 2018, 'Efficacy of a tool to predict short-term mortality in older people presenting at emergency departments: Protocol for a multi-centre cohort study', Archives of Gerontology and Geriatrics, vol. 76, pp. 169 - 174, http://dx.doi.org/10.1016/j.archger.2018.02.014
2018
Cardona M; O'Sullivan M; Lewis ET; Turner RM; Garden F; Alkhouri H; Asha S; Mackenzie J; Perkins M; Suri S; Holdgate A; Winoto L; Chang DW; Gallego-Luxan B; McCarthy S; Hillman K; Breen D, 2018, 'Prospective Validation of a Checklist to Predict Short-term Death in Older Patients After Emergency Department Admission in Australia and Ireland', Academic Emergency Medicine, http://dx.doi.org/10.1111/acem.13664
2018
Cardona M; Turner RM; Chapman A; Alkhouri H; Lewis ET; Jan S; Nicholson M; Parr M; Williamson M; Hillman K, 2018, 'Who Benefits from Aggressive Rapid Response System Treatments Near the End of Life? A Retrospective Cohort Study', Joint Commission Journal on Quality and Patient Safety, vol. 44, pp. 505 - 513, http://dx.doi.org/10.1016/j.jcjq.2018.04.001
2018
Cardona M; Lewis E; Kristensen M; Skjot-Arkil H; Ekmann A; Nygaard H; Jensen J; Jensen R; Pedersen J; Turner R; Garden F; Alkhouri H; Asha S; Mackenzie J; Perkins M; Suri S; Holdgate A; Winoto L; Chang D; Gallego-Luxan B; McCarthy S; Petersen J; Jensen B; Mogensen C; Hillman K; Brabrand M, 2018, 'Predictive validity of the CriSTAL tool for short-term mortality in older people presenting at Emergency Departments: a prospective study', European Geriatric Medicine, vol. 9, pp. 891 - 901, http://dx.doi.org/10.1007/s41999-018-0123-6
2018
Powell E; Alkhouri H; McCarthy S; Mackenzie J; Fogg T; Vassiliadis J; Cresswell C, 2018, 'A sequential case series of 23 intubations in a rural emergency department in New Zealand', Australian Journal of Rural Health, vol. 26, pp. 48 - 55, http://dx.doi.org/10.1111/ajr.12366
2018
Alkhouri H; Vassiliadis J; Murray M; Mackenzie J; Tzannes A; McCarthy S; Fogg T, 2017, 'Emergency airway management in Australian and New Zealand emergency departments: A multicentre descriptive study of 3710 emergency intubations', EMA - Emergency Medicine Australasia, vol. 29, pp. 499 - 508, http://dx.doi.org/10.1111/1742-6723.12815
2017
Fogg T; Alkhouri H; Vassiliadis J, 2016, 'The Royal North Shore Hospital Emergency Department airway registry: Closing the audit loop', EMA - Emergency Medicine Australasia, vol. 28, pp. 27 - 33, http://dx.doi.org/10.1111/1742-6723.12496
2016
Alkhouri H; Moir LM; Armour CL; Hughes JM, 2014, 'CXCL1 is a negative regulator of mast cell chemotaxis to airway smooth muscle cell products in vitro', Clinical and Experimental Allergy, vol. 44, pp. 381 - 392, http://dx.doi.org/10.1111/cea.12224
2014
Alkhouri H; Cha V; Tong K; Moir LM; Armour CL; Hughes JM, 2014, 'Human Lung Mast Cell Products Regulate Airway Smooth Muscle CXCL10 Levels', Journal of Allergy, vol. 2014, pp. 1 - 13, http://dx.doi.org/10.1155/2014/875105
2014
Rahman MM; Alkhouri H; Tang F; Che W; Ge Q; Ammit AJ, 2014, 'Sphingosine 1-phosphate induces neutrophil chemoattractant il-8: Repression by steroids', PLoS ONE, vol. 9, http://dx.doi.org/10.1371/journal.pone.0092466
2014
Alkhouri H; Rumzhum NN; Rahman MM; Fitzpatrick M; De Pedro M; Oliver BG; Bourke JE; Ammit AJ, 2014, 'TLR2 activation causes tachyphylaxis to β2-Agonists in vitro and ex vivo: Modelling bacterial exacerbation', Allergy: European Journal of Allergy and Clinical Immunology, vol. 69, pp. 1215 - 1222, http://dx.doi.org/10.1111/all.12449
2014
Chen L; Ge Q; Tjin G; Alkhouri H; Deng L; Brandsma CA; Adcock I; Timens W; Postma D; Burgess JK; Black JL; Oliver BGG, 2014, 'Effects of cigarette smoke extract on human airway smooth muscle cells in COPD', European Respiratory Journal, vol. 44, pp. 634 - 646, http://dx.doi.org/10.1183/09031936.00171313
2014
Alkhouri H; Poppinga WJ; Tania NP; Ammit A; Schuliga M, 2014, 'Regulation of pulmonary inflammation by mesenchymal cells', Pulmonary Pharmacology and Therapeutics, vol. 29, pp. 156e165 - 156e165, http://dx.doi.org/10.1016/j.pupt.2014.03.001
2014
Che W; Parmentier J; Seidel P; Manetsch M; Ramsay EE; Alkhouri H; Ge Q; Armour CL; Ammit AJ, 2014, 'Corticosteroids inhibit sphingosine 1-phosphate-induced interleukin-6 secretion from human airway smooth muscle via mitogen-activated protein kinase phosphatase 1-mediated repression of mitogen and stress-activated protein kinase 1', American Journal of Respiratory Cell and Molecular Biology, vol. 50, pp. 358 - 368, http://dx.doi.org/10.1165/rcmb.2013-0208OC
2014
Hirota JA; Im H; Rahman MM; Rumzhum NN; Manetsch M; Pascoe CD; Bunge K; Alkhouri H; Oliver BG; Ammit AJ, 2013, 'The nucleotide-binding domain and leucine-rich repeat protein-3 inflammasome is not activated in airway smooth muscle upon toll-like receptor-2 ligation', American Journal of Respiratory Cell and Molecular Biology, vol. 49, pp. 517 - 524, http://dx.doi.org/10.1165/rcmb.2013-0047OC
2013
Manetsch M; Rahman MM; Patel BS; Ramsay EE; Rumzhum NN; Alkhouri H; Ge Q; Ammit AJ, 2013, 'Long-Acting β2-Agonists Increase Fluticasone Propionate-Induced Mitogen-Activated Protein Kinase Phosphatase 1 (MKP-1) in Airway Smooth Muscle Cells', PLoS ONE, vol. 8, http://dx.doi.org/10.1371/journal.pone.0059635
2013
Tan X; Alrashdan YA; Alkhouri H; Oliver BGG; Armour CL; Hughes JM, 2013, 'Airway smooth muscle CXCR3 ligand production: Regulation by JAK-STAT1 and intracellular Ca2+', American Journal of Physiology - Lung Cellular and Molecular Physiology, vol. 304, http://dx.doi.org/10.1152/ajplung.00356.2012
2013
Jung M; Lord MS; Cheng B; Lyons JG; Alkouri H; Hughes M; McCarthy S; Iozzo R; Whitelock J, 2013, 'Mast cells produce novel shorter forms of perlecan that contain functional endorepellin: A role in angiogenesis and wound healing', The Journal of Biological Chemistry, vol. 288, pp. 3289 - 3304, http://dx.doi.org/10.1074/jbc.M112.387811
2013
Alrashdan YA; Alkhouri H; Chen E; Lalor DJ; Poniris M; Henness S; Brightling CE; Burgess JK; Armour CL; Ammit AJ; Hughes JM, 2012, 'Asthmatic airway smooth muscle CXCL10 production: Mitogen-activated protein kinase JNK involvement', American Journal of Physiology - Lung Cellular and Molecular Physiology, vol. 302, http://dx.doi.org/10.1152/ajplung.00232.2011
2012
Seidel P; Alkhouri H; Lalor DJ; Burgess JK; Armour CL; Hughes JM, 2012, 'Thiazolidinediones inhibit airway smooth muscle release of the chemokine CXCL10: in vitro comparison with current asthma therapies', Respiratory Research, vol. 13, http://dx.doi.org/10.1186/1465-9921-13-90
2012
Tan X; Khalil N; Tesarik C; Vanapalli K; Yaputra V; Alkhouri H; Oliver BGG; Armour CL; Margaret Hughes J, 2012, 'Th1 cytokine-induced syndecan-4 shedding by airway smooth muscle cells is dependent on mitogen-activated protein kinases', American Journal of Physiology - Lung Cellular and Molecular Physiology, vol. 302, http://dx.doi.org/10.1152/ajplung.00167.2011
2012
Alkhouri H; Hollins F; Moir LM; Brightling CE; Armour CL; Hughes JM, 2011, 'Human lung mast cells modulate the functions of airway smooth muscle cells in asthma', Allergy: European Journal of Allergy and Clinical Immunology, vol. 66, pp. 1231 - 1241, http://dx.doi.org/10.1111/j.1398-9995.2011.02616.x
2011
Moutzouris JP; Che W; Ramsay EE; Manetsch M; Alkhouri H; Bjorkman AM; Schuster F; Ge Q; Ammit AJ, 2010, 'Proteasomal inhibition upregulates the endogenous MAPK deactivator MKP-1 in human airway smooth muscle: Mechanism of action and effect on cytokine secretion', Biochimica et Biophysica Acta - Molecular Cell Research, vol. 1803, pp. 416 - 423, http://dx.doi.org/10.1016/j.bbamcr.2009.12.007
2010
Ammit AJ; Moir LM; Oliver BG; Hughes JM; Alkhouri H; Ge Q; Burgess JK; Black JL; Roth M, 2007, 'Effect of IL-6 trans-signaling on the pro-remodeling phenotype of airway smooth muscle', American Journal of Physiology - Lung Cellular and Molecular Physiology, vol. 292, http://dx.doi.org/10.1152/ajplung.00230.2006
2007
Chhabra J; Li YZ; Alkhouri H; Blake AE; Ge Q; Armour CL; Hughes JM, 2007, 'Histamine and tryptase modulate asthmatic airway smooth muscle GM-CSF and RANTES release', European Respiratory Journal, vol. 29, pp. 861 - 870, http://dx.doi.org/10.1183/09031936.00106306
2007
Conference Papers
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Hughes JM; Wai-Shing M; Krimmer D; Oliver BGG; Armour CL; Alkhouri H, 2013, 'DIFFERENTIAL RESPONSES OF CENTRAL AND PERIPHERAL LUNG FIBROBLASTS TO ACTIVATED MAST CELL PRODUCTS', in RESPIROLOGY, WILEY-BLACKWELL, pp. 41 - 41, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000315589700150&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
2013
Alkhouri H; Burgess J; Armour C; Hughes JM, 2013, 'Human lung mast cells alter asthmatic airway epithelial cell function', in EUROPEAN RESPIRATORY JOURNAL, EUROPEAN RESPIRATORY SOC JOURNALS LTD, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000209370402533&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
2013
Hughes M; Burgess J; Armour C; Alkhouri H, 2013, 'HUMAN LUNG MAST CELLS ALTER AIRWAY EPITHELIAL CELL FUNCTION', in RESPIROLOGY, WILEY-BLACKWELL, pp. 25 - 25, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000315589700090&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
2013
Alkhouri H; Wai-Shing M; Krimmer D; Oliver B; Armour C; Hughes JM, 2012, 'The effects of human lung mast cell products on the synthetic functions of lung fibroblasts', in EUROPEAN RESPIRATORY JOURNAL, EUROPEAN RESPIRATORY SOC JOURNALS LTD
2012
Tan X; Alrashdan Y; Alkhouri H; Yaputra V; Armour CL; Oliver BG; Hughes JM, 2011, 'Th1-Cytokine Induced STAT1 And JNK Phosphorylation Is Altered In Airway Smooth Muscle Cells From People With Asthma', in AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, AMER THORACIC SOC, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000208770303152&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
2011
Alkhouri H; Wasinger V; Moir LM; Armour CL; Hughes JM, 2011, 'Proteomic Identification Of Factors That Regulate Mast Cell Localization To The Airway Smooth Muscle Cells In Asthma', in AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, AMER THORACIC SOC, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000208770303169&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
2011
Hughes J; Khalil N; Vanapalli K; Yaputra V; Alkhouri H; Oliver BG; Armour CL, 2010, 'Airway Smooth Muscle Cells From People With Asthma Shed Syndecan-4', in AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, AMER THORACIC SOC, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000208771001296&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
2010
Alkhouri H; Roth M; Oliver B; Armour CL; Hughes JM, 2009, 'Role of C/EBP-Isoforms in IP-10 and IL-6 Production by Human Airway Smooth Muscle Cells.', in AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, AMER THORACIC SOC, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000208733106023&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a
2009
Alkhouri H; Tong K; Cha V; Moir LM; Armour CL; Hughes JM, 2009, 'Asthmatic Airway Smooth Muscle CXCL10 Release Is Modulated by Mast Cell Products.', in AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, AMER THORACIC SOC, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000208733103250&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2009
Conference Abstracts
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Jung M; Lord M; Cheng B; Lyons JG; Alkhouri H; Hughes JM; McCarthy S; Iozzo R; Whitelock J, 2012, 'Mast cells produce novel shorter forms of perlecan that contain functional endorepellin: A role in angiogenesis and wound healing', in GLYCOBIOLOGY, OXFORD UNIV PRESS INC, San Diego, CA, Vol. 22, pp. 1627 - 1628, presented at Joint Meeting of the Society-for-Glycobiology and American-Society-for-Matrix-Biology, San Diego, CA, 11 November 2012 - 14 November 2012, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000310368700326&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2012