Darren Saunders

Associate Professor
Associate Director

Darren is a cancer biologist and Associate Professor in Medicine at UNSW, where he heads the Ubiquitin Signaling Lab - researching fundamental mechanisms of protein homeostasis and cell signalling in cancer and neurodegeneration. Darren undertook post-doctoral training at the Garvan Institute and University of British Columbia and has held fellowships from the US Dept. of Defense and Cancer Institute NSW. Darren is secretary of Science and Technology Australia and a regular commentator on television and radio,resident scientist on ABC TV’s The Drum.


Broad Research Areas: Cancer; Cell Biology and Gene Regulation; Biochemistry; Genetics - Genome Analysis; Biochemistry
    
Specific Research Keywords: Cancer; Molecular Oncology, Ubiquitin, Cancer Metabolism, Proteomics, Serpin, Proteosatsis, Neurodegeneration, Functional Genomics, High content imaging.
        

 

Publications

Journal articles
add
Nerstedt A; Kurhe Y; Cansby E; Caputo M; Gao L; Vorontsov E; Ståhlman M; Nuñez-Durán E; Borén J; Marschall HU; Mashek DG; Saunders DN; Sihlbom C; Hoy AJ; Mahlapuu M, 2020, 'Lipid droplet-associated kinase STK25 regulates peroxisomal activity and metabolic stress response in steatotic liver', Journal of lipid research, vol. 61, pp. 178 - 191, http://dx.doi.org/10.1194/jlr.RA119000316
2020
Kennedy SP; Han JZR; Portman N; Nobis M; Hastings JF; Murphy KJ; Latham SL; Cadell AL; Miladinovic D; Marriott GR; O'Donnell YEI; Shearer RF; Williams JT; Munoz AG; Cox TR; Watkins DN; Saunders DN; Timpson P; Lim E; Kolch W; Croucher DR, 2019, 'Targeting promiscuous heterodimerization overcomes innate resistance to ERBB2 dimerization inhibitors in breast cancer', Breast Cancer Research, vol. 21, pp. 43, http://dx.doi.org/10.1186/s13058-019-1127-y
2019
Balaban S; Nassar ZD; Zhang AY; Hosseini-Beheshti E; Centenera MM; Schreuder M; Lin HM; Aishah A; Varney B; Liu-Fu F; Lee LS; Nagarajan SR; Shearer RF; Hardie RA; Raftopulos NL; Kakani MS; Saunders DN; Holst J; Horvath LG; Butler LM; Hoy AJ, 2019, 'Extracellular fatty acids are the major contributor to lipid synthesis in prostate cancer', Molecular Cancer Research, vol. 17, pp. 949 - 962, http://dx.doi.org/10.1158/1541-7786.MCR-18-0347
2019
Bax M; McKenna J; Do-Ha D; Stevens CH; Higginbottom S; Balez R; Cabral-da-Silva MEC; Farrawell NE; Engel M; Poronnik P; Yerbury JJ; Saunders DN; Ooi L, 2019, 'The Ubiquitin Proteasome System Is a Key Regulator of Pluripotent Stem Cell Survival and Motor Neuron Differentiation', CELLS, vol. 8, http://dx.doi.org/10.3390/cells8060581
2019
Rodrigo C; Tedla N; Thomas S; Polly P; Herbert C; Velan G; Saunders DN, 2019, 'Using Narratives to Teach Students Enrolled in Science and Medical Science Bachelor’s Degree Programs', Medical Science Educator, vol. 29, pp. 357 - 361, http://dx.doi.org/10.1007/s40670-019-00698-1
2019
Hastings JF; Han JZR; Shearer RF; Kennedy SP; Iconomou M; Saunders DN; Croucher DR, 2018, 'Dissecting multi-protein signaling complexes by bimolecular complementation affinity purification (Bicap)', Journal of Visualized Experiments, vol. 2018, http://dx.doi.org/10.3791/57109
2018
Amberg A; Saunders D, 2018, 'Cancer In The News: Bias And Quality In Media Reporting Of Cancer Research', , http://dx.doi.org/10.1101/388488
2018
Balaban S; Lee LS; Varney B; Aishah A; Gao Q; Shearer RF; Saunders DN; Grewal T; Hoy AJ, 2018, 'Heterogeneity of fatty acid metabolism in breast cancer cells underlies differential sensitivity to palmitate-induced apoptosis', Molecular Oncology, vol. 12, pp. 1623 - 1638, http://dx.doi.org/10.1002/1878-0261.12368
2018
Shearer RF; Frikstad KAM; McKenna J; McCloy RA; Deng N; Burgess A; Stokke T; Patzke S; Saunders DN, 2018, 'The E3 ubiquitin ligase UBR5 regulates centriolar satellite stability and primary cilia', Molecular Biology of the Cell, vol. 29, pp. 1542 - 1554, http://dx.doi.org/10.1091/mbc.E17-04-0248
2018
Farrawell NE; Lambert-Smith I; Mitchell K; McKenna J; McAlary L; Ciryam P; Vine KL; Saunders DN; Yerbury JJ, 2018, 'SOD1A4V aggregation alters ubiquitin homeostasis in a cell model of ALS', Journal of cell science, vol. 131, http://dx.doi.org/10.1242/jcs.209122
2018
Belfiore L; Saunders DN; Ranson M; Thurecht KJ; Storm G; Vine KL, 2018, 'Towards clinical translation of ligand-functionalized liposomes in targeted cancer therapy: Challenges and opportunities', Journal of Controlled Release, vol. 277, pp. 1 - 13, http://dx.doi.org/10.1016/j.jconrel.2018.02.040
2018
Nagarajan SR; Brandon AE; McKenna JA; Shtein HC; Nguyen TQ; Suryana E; Poronnik P; Cooney GJ; Saunders DN; Hoy AJ, 2017, 'Insulin and diet-induced changes in the ubiquitin-modified proteome of rat liver', PLoS ONE, vol. 12, http://dx.doi.org/10.1371/journal.pone.0174431
2017
Hardie R-A; van Dam E; Cowley M; Han T-L; Balaban S; Pajic M; Pinese M; Iconomou M; Shearer RF; McKenna J; Miller D; Waddell N; Pearson JV; Grimmond SM; Sazanov L; Biankin AV; Villas-Boas S; Hoy AJ; Turner N; Saunders DN, 2017, 'Mitochondrial mutations and metabolic adaptation in pancreatic cancer', CANCER & METABOLISM, vol. 5, http://dx.doi.org/10.1186/s40170-017-0164-1
2017
Harris NLE; Vennin C; Conway JRW; Vine KL; Pinese M; Cowley MJ; Shearer RF; Lucas MC; Herrmann D; Allam AH; Pajic M; Morton JP; Biankin AV; Ranson M; Timpson P; Saunders DN, 2017, 'SerpinB2 regulates stromal remodelling and local invasion in pancreatic cancer', Oncogene, vol. 36, pp. 4288 - 4298, http://dx.doi.org/10.1038/onc.2017.63
2017
Nagarajan SR; Brandon AE; McKenna JA; Shtein HC; Nguyen TQ; Suryana E; Poronnik P; Cooney GJ; Saunders DN; Hoy AJ, 2017, 'Correction: Insulin and diet-induced changes in the ubiquitin-modified proteome of rat liver (PLoS ONE (2017) 12:3 (e0174431) DOI: 10.1371/journal.pone.0174431)', PLoS ONE, vol. 12, http://dx.doi.org/10.1371/journal.pone.0184610
2017
Xu H; Di Antonio M; McKinney S; Mathew V; Ho B; O'Neil NJ; Santos ND; Silvester J; Wei V; Garcia J; Kabeer F; Lai D; Soriano P; Banáth J; Chiu DS; Yap D; Le DD; Ye FB; Zhang A; Thu K; Soong J; Lin SC; Tsai AHC; Osako T; Algara T; Saunders DN; Wong J; Xian J; Bally MB; Brenton JD; Brown GW; Shah SP; Cescon D; Mak TW; Caldas C; Stirling PC; Hieter P; Balasubramanian S; Aparicio S, 2017, 'CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours', Nature Communications, vol. 8, http://dx.doi.org/10.1038/ncomms14432
2017
Hoy AJ; Balaban S; Saunders DN, 2017, 'Adipocyte–Tumor Cell Metabolic Crosstalk in Breast Cancer', Trends in Molecular Medicine, vol. 23, pp. 381 - 392, http://dx.doi.org/10.1016/j.molmed.2017.02.009
2017
Ciryam P; Lambert-Smith IA; Bean DM; Freer R; Cid F; Tartaglia GG; Saunders DN; Wilson MR; Oliver SG; Morimoto RI; Dobson CM; Vendruscolo M; Favrin G; Yerbury JJ, 2017, 'Spinal motor neuron protein supersaturation patterns are associated with inclusion body formation in ALS', Proceedings of the National Academy of Sciences of the United States of America, vol. 114, pp. E3935 - E3943, http://dx.doi.org/10.1073/pnas.1613854114
2017
Balaban S; Shearer RF; Lee LS; van Geldermalsen M; Schreuder M; Shtein HC; Cairns R; Thomas KC; Fazakerley DJ; Grewal T; Holst J; Saunders DN; Hoy AJ, 2017, 'Adipocyte lipolysis links obesity to breast cancer growth: adipocyte-derived fatty acids drive breast cancer cell proliferation and migration', CANCER & METABOLISM, vol. 5, http://dx.doi.org/10.1186/s40170-016-0163-7
2017
Chen L; Watson C; Morsch M; Cole NJ; Chung RS; Saunders DN; Yerbury JJ; Vine KL, 2017, 'Improving the delivery of SOD1 antisense oligonucleotides to motor neurons using calcium phosphate-lipid nanoparticle', Frontiers in Neuroscience, vol. 11, http://dx.doi.org/10.3389/fnins.2017.00476
2017
Yerbury JJ; Ooi L; Dillin A; Saunders DN; Hatters DM; Beart PM; Cashman NR; Wilson MR; Ecroyd H, 2016, 'Walking the tightrope: Proteostasis and neurodegenerative disease', Journal of Neurochemistry, vol. 137, pp. 489 - 505, http://dx.doi.org/10.1111/jnc.13575
2016
Liu L; Phua YW; Lee RS; Ma X; Jenkins Y; Novy K; Humphrey ES; Chan H; Shearer R; Ong PC; Dai W; Saunders DN; Lucet IS; Daly RJ, 2016, 'Homo- and heterotypic association regulates signaling by the SgK269/PEAK1 and SgK223 pseudokinases', Journal of Biological Chemistry, vol. 291, pp. 21571 - 21583, http://dx.doi.org/10.1074/jbc.M116.748897
2016
Iconomou M; Saunders DN, 2016, 'Systematic approaches to identify E3 ligase Substrates', Biochemical Journal, vol. 473, pp. 4083 - 4101, http://dx.doi.org/10.1042/BCJ20160719
2016
Saunders DN; Croucher D, 2016, 'Dissecting and Deconvoluting Multi-molecular Complexes - Principles of Systems Biology, No. 7', Cell Systems, vol. 3, pp. 3 - 6, http://dx.doi.org/10.1016/j.cels.2016.07.010
2016
Shearer RF; Saunders DN, 2016, 'Regulation of primary cilia formation by the ubiquitin-proteasome system', Biochemical Society Transactions, vol. 44, pp. 1265 - 1271, http://dx.doi.org/10.1042/BST20160174
2016
Croucher DR; Iconomou M; Hastings JF; Kennedy SP; Shearer RF; McKenna J; Wan A; Lau J; Aparicio S; Saunders DN, 2016, 'Bimolecular complementation affinity purification (BiCAP) reveals dimer-specific protein interactions for ERBB2 dimers', Science Signaling, vol. 9, pp. ra69 - ra69, http://dx.doi.org/10.1126/scisignal.aaf0793
2016
Lee JA; Yerbury JJ; Farrawell N; Shearer RF; Constantinescu P; Hatters DM; Schroder WA; Suhrbier A; Wilson MR; Saunders DN; Ranson M, 2015, 'SerpinB2 (PAI-2) modulates proteostasis via binding misfolded proteins and promotion of cytoprotective inclusion formation', PLoS ONE, vol. 10, http://dx.doi.org/10.1371/journal.pone.0130136
2015
Farrawell NE; Lambert-Smith IA; Warraich ST; Blair IP; Saunders DN; Hatters DM; Yerbury JJ, 2015, 'Distinct partitioning of ALS associated TDP-43, FUS and SOD1 mutants into cellular inclusions', Scientific Reports, vol. 5, http://dx.doi.org/10.1038/srep13416
2015
Shearer RF; Saunders DN, 2015, 'Experimental design for stable genetic manipulation in mammalian cell lines: Lentivirus and alternatives', Genes to Cells, vol. 20, pp. 1 - 10, http://dx.doi.org/10.1111/gtc.12183
2015
Shearer RF; Iconomou M; Watts CKW; Saunders DN, 2015, 'Functional roles of the E3 Ubiquitin Ligase UBR5 in cancer', Molecular Cancer Research, vol. 13, pp. 1523 - 1532, http://dx.doi.org/10.1158/1541-7786.MCR-15-0383
2015
Saunders D, 2015, 'Integrated approaches to understanding cancer metabolism', in CLINICAL ENDOCRINOLOGY, WILEY, Adelaide, AUSTRALIA, Vol. 84, pp. 12 - 12, presented at Annual Scientific Meeting of the Endocrine-Society-of-Australia, Adelaide, AUSTRALIA, 23 August 2015 - 26 August 2015, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000372310400033&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2015
Saunders DN; Falkenberg KJ; Simpson KJ, 2014, 'High-throughput approaches to measuring cell death', Cold Spring Harbor Protocols, vol. 2014, pp. 591 - 601, http://dx.doi.org/10.1101/pdb.top072561
2014
Falkenberg KJ; Simpson KJ, 2014, 'A high-throughput, multiplex cell death assay using an RNAi screening approach', Cold Spring Harbor Protocols, vol. 2014, pp. 663 - 676, http://dx.doi.org/10.1101/pdb.prot080267
2014
Ong SS; Goktug AN; Elias A; Wu J; Saunders D; Chen T, 2014, 'Stability of the human pregnane X receptor is regulated by E3 ligase UBR5 and serine/threonine kinase DYRK2', Biochemical Journal, vol. 459, pp. 193 - 203, http://dx.doi.org/10.1042/BJ20130558
2014
Gudjonsson T; Altmeyer M; Savic V; Toledo L; Dinant C; Grøfte M; Bartkova J; Poulsen M; Oka Y; Bekker-Jensen S; Mailand N; Neumann B; Heriche JK; Shearer R; Saunders D; Bartek J; Lukas J; Lukas C, 2014, 'Erratum: TRIP12 and UBR5 suppress spreading of chromatin ubiquitylation at damaged chromosomes(Cell (2012) 150 17 (697709 ))', Cell, vol. 159, pp. 1476 - 1477, http://dx.doi.org/10.1016/j.cell.2014.11.027
2014
Saunders D, 2013, 'What is Cancer?', in The Explainer From Deja Vu to Why the Sky Is Blue, and Other Conundrums, CSIRO PUBLISHING
2013
Croucher DR; Hochgräfe F; Zhang L; Liu L; Lyons RJ; Rickwood D; Tactacan CM; Browne BC; Ali N; Chan H; Shearer R; Gallego-Ortega D; Saunders DN; Swarbrick A; Daly RJ, 2013, 'Involvement of Lyn and the atypical kinase SgK269/PEAK1 in a basal breast cancer signaling pathway', Cancer Research, vol. 73, pp. 1969 - 1980, http://dx.doi.org/10.1158/0008-5472.CAN-12-1472
2013
Gudjonsson T; Altmeyer M; Savic V; Toledo L; Grofte M; Bekker-Jensen S; Mailand N; Neumann B; Heriche J; Pepperkok R; Ellenberg J; Shearer R; Saunders D; Bartek J; Lucas J; Lucas C, 2012, 'TRIP12 and UBR5 suppress spreading of chromatin ubiquitylation at damaged chromosomes', Cell, vol. 150, pp. 697 - 709, http://dx.doi.org/10.1016/j.cell.2012.06.039
2012
Roering M; Herr R; Heilman K; Braun S; Halbach S; Saunders D; Brummer T, 2012, 'Distinct requirement for an intact dimer interface in wild-type, V600E and kinase-dead B-Raf signalling', EMBO Journal, vol. 31, pp. 2629 - 2647, http://dx.doi.org/10.1038/emboj.2012.100
2012
Saunders D; Shearer R; Tindall E; Robertson J; Decker A; Wilson JA; Hayes V, 2012, 'A novel SERPINA1 mutation causing serum alpha(1)-antitrypsin deficiency', PLoS One, vol. 7, pp. e51762, http://dx.doi.org/10.1371/journal.pone.0051762
2012
Cochran BJ; Saunders D; Croucher DR; Lobov S; Ranson M, 2011, 'Dependence on endocytic receptor binding via a minimal binding motif underlies the differential prognostic profiles of serpinE1 and serpinB2 in cancer', The Journal of Biological Chemistry, vol. 286, pp. 24467 - 24475, http://dx.doi.org/10.1074/jbc.M111.225706
2011
Schrader KA; Masciari S; Boyd N; Salamanca C; Senz J; Saunders DN; Yorida E; Maines-Bandiera S; Kaurah P; Tung N; Robson ME; Ryan PD; Olopade OI; Domchek SM; Ford J; Isaacs C; Brown P; Balmana J; Razzak AR; Miron P; Coffey K; Terry MB; John EM; Andrulis IL; Knight JA; O'Malley FP; Daly M; Bender P; Moore R; Southey MC; Hopper JL; Garber JE; Huntsman DG, 2011, 'Germline mutations in CDH1 are infrequent in women with early-onset or familial lobular breast cancers', Journal of Medical Genetics, vol. 48, pp. 64 - 68, http://dx.doi.org/10.1136/jmg.2010.079814
2011
Watts CK; Saunders DN, 2011, 'Effects of EDD on p53 function are context-specific', Journal of Biological Chemistry, vol. 286, http://dx.doi.org/10.1074/jbc.L110.182527
2011
Hu G; Wang X; Saunders DN; Henderson M; Russell AJ; Herring BP; Zhou J, 2011, 'Modulation of myocardin function by the ubiquitin E3 ligase UBR5 (The Journal Of Biological Chemistry (2010) 9285, (11800-11809))', Journal of Biological Chemistry, vol. 286, pp. 25416, http://dx.doi.org/10.1074/jbc.A109.079384
2011
Watts CK; Saunders D, 2011, 'Effects of EDD on p53 function are context-specific', The Journal of Biological Chemistry, vol. 286, pp. 1 - 13, http://dx.doi.org/10.1074/jbc.N110.182527
2011
Potratz JC; Saunders DN; Wai DH; Ng TL; McKinney SE; Carboni JM; Gottardis MM; Triche TJ; Jürgens H; Pollak MN; Aparicio SA; Sorensen PHB, 2010, 'Synthetic lethality screens reveal RPS6 and MST1R as modifiers of insulin-like growth factor-1 receptor inhibitor activity in childhood sarcomas', Cancer Research, vol. 70, pp. 8770 - 8781, http://dx.doi.org/10.1158/0008-5472.CAN-10-1093
2010
Hu G; Wang XL; Saunders D; Henderson M; Russell AJ; Herring BP; Zhou J, 2010, 'Modulation of myocardin function by the ubiquitin E3 ligase UBR5', The Journal of Biological Chemistry, vol. 285, pp. 11800 - 11809, http://dx.doi.org/10.1074/jbc.M109.079384
2010
Saunders D, 2009, 'Backlogged system in Australia shuts out new investigators', Nature, vol. 458, pp. 281, http://dx.doi.org/10.1038/458281d
2009
Lobov S; Croucher DR; Saunders DN; Ranson M, 2008, 'Plasminogen activator inhibitor type 2 inhibits cell surface associated tissue plasminogen activator in vitro: Potential receptor interactions', Thrombosis and Haemostasis, vol. 100, pp. 319 - 329, http://dx.doi.org/10.1160/TH08-02-0119
2008
O'Brien PM; Davies MJ; Scurry JP; Smith AN; Barton CA; Henderson MJ; Saunders DN; Gloss BS; Patterson KI; Clancy JL; Heinzelmann-Schwarz VA; Murali R; Scolyer RA; Zeng Y; Williams ED; Scurr L; DeFazio A; Quinn DI; Watts CKW; Hacker NF; Henshall SM; Sutherland RL, 2008, 'The E3 ubiquitin ligase EDD is an adverse prognostic factor for serous epithelial ovarian cancer and modulates cisplatin resistance in vitro (British Journal of Cancer (2008) 98, (1085-1093) DOI: 10.1038/sj.bjc.6604281))', British Journal of Cancer, vol. 98, pp. 1880, http://dx.doi.org/10.1038/sj.bjc.6604419
2008
Croucher DR; Saunders DN; Lobov S; Ranson M, 2008, 'Revisiting the biological roles of PAI2 (SERPINB2) in cancer', Nature Reviews Cancer, vol. 8, pp. 535 - 545, http://dx.doi.org/10.1038/nrc2400
2008
Poon SSS; Wong JT; Saunders DN; Ma QC; McKinney S; Fee J; Aparicio SAJR, 2008, 'Intensity calibration and automated cell cycle gating for high-throughput image-based siRNA screens of mammalian cells', Cytometry Part A, vol. 73, pp. 904 - 917, http://dx.doi.org/10.1002/cyto.a.20624
2008
Stillfried GE; Saunders DN; Ranson M, 2007, 'Plasminogen binding and activation at the breast cancer cell surface: The integral role of urokinase activity', Breast Cancer Research, vol. 9, http://dx.doi.org/10.1186/bcr1647
2007
Croucher DR; Saunders DM; Stillfried GE; Ranson M, 2007, 'A structural basis for differential cell signalling by PAI-1 and PAI-2 in breast cancer cells', Biochemical Journal, vol. 408, pp. 203 - 210, http://dx.doi.org/10.1042/BJ20070767
2007
Croucher D; Saunders DN; Ranson M, 2006, 'The urokinase/PAI-2 complex: A new high affinity ligand for the endocytosis receptor low density lipoprotein receptor-related protein', Journal of Biological Chemistry, vol. 281, pp. 10206 - 10213, http://dx.doi.org/10.1074/jbc.M513645200
2006
Saunders DN; Hird SL; Withington SL; Dunwoodie SL; Henderson MJ; Biben C; Sutherland RL; Ormandy CJ; Watts CKW, 2004, 'Erratum: Edd, the murine ortholog of the hyperplastic discs (hyd) gene, is essential for yolk sac vascularization and chorioallantoic fusion (Molecular and Cellular Biology (2004) 24: 16 (7225-7234))', Molecular and Cellular Biology, vol. 24, pp. 9262, http://dx.doi.org/10.1128/MCB.24.20.9262.2004
2004
Williams DL; Risse B; Sam K; Saunders D; Orlin S; Baker MS; Jensen PJ; Lavker RM, 1999, 'Plasminogen activator inhibitor type 2 in human corneal epithelium', Investigative Ophthalmology and Visual Science, vol. 40, pp. 1669 - 1675
1999
Saunders DN; Buttigieg KML; Gould A; McPhun V; Baker MS, 1998, 'Immunological detection of conformational neoepitopes associated with the serpin activity of plasminogen activator inhibitor type-2', Journal of Biological Chemistry, vol. 273, pp. 10965 - 10971, http://dx.doi.org/10.1074/jbc.273.18.10965
1998
Ranson M; Andronicos N; Saunders D; Baker MS, 1998, 'Rapid auto-catalytic processing of Gluplasminogen occurs on malignant breast cancer cell-surfaces', Fibrinolysis and Proteolysis, vol. 12, pp. 14
1998
Saunders D; Baker MS, 1998, 'Structure function relationships of plasminogen activator inhibitor type-2 (PAI-2)', Fibrinolysis and Proteolysis, vol. 12, pp. 15
1998
Hang MTN; Ranson M; Saunders DN; Liang XM; Bunn CL; Baker MS, 1998, 'Pharmacokinetics and biodistribution of recombinant human plasminogen activator inhibitor type 2 (PAI-2) in control and tumour xenograft-bearing mice', Fibrinolysis and Proteolysis, vol. 12, pp. 145 - 154, http://dx.doi.org/10.1016/S0268-9499(98)80296-8
1998
Tsatas D; Baker MS; Saunders D; Rice GE, 1997, 'Expression of "relaxed" conformation of pai-2 and lrp in human term gestational tissues', Fibrinolysis and Proteolysis, vol. 11, pp. 56
1997
Saunders D; Baker M, 1995, 'Serpins: The essential inhibitors', Today's Life Science, vol. 7, pp. 42 - 47
1995