Chris Jolly

Senior Research Fellow

publications

Journal articles
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Lee Q; Padula MP; Pinello N; Williams SH; O’Rourke MB; Fumagalli MJ; Orkin JD; Song R; Shaban B; Brenner O; Pimanda JE; Weninger W; de Souza WM; Melin AD; Wong JJL; Crim MJ; Monette S; Roediger B; Jolly CJ, 2020, 'Murine and related chapparvoviruses are nephro-tropic and produce novel accessory proteins in infected kidneys', PLoS Pathogens, vol. 16, pp. e1008262, http://dx.doi.org/10.1371/journal.ppat.1008262
2020
Gall MG; Zhang HE; Lee Q; Jolly CJ; McCaughan GW; Cook A; Roediger B; Gorrell MD, 2019, 'Immune regeneration in irradiated mice is not impaired by the absence of DPP9 enzymatic activity', Scientific Reports, vol. 9, http://dx.doi.org/10.1038/s41598-019-43739-w
2019
Poyntz HC; Jones A; Jauregui R; Young W; Gestin A; Mooney A; Lamiable O; Altermann E; Schmidt A; Gasser O; Weyrich L; Jolly CJ; Linterman MA; Gros GL; Hawkins ED; Forbes-Blom E, 2019, 'Genetic regulation of antibody responsiveness to immunization in substrains of BALB/c mice', Immunology and Cell Biology, vol. 97, pp. 39 - 53, http://dx.doi.org/10.1111/imcb.12199
2019
Thientosapol ES; Bosnjak D; Durack T; Stevanovski I; Van Geldermalsen M; Holst J; Jahan Z; Shepard C; Weninger W; Kim B; Brink R; Jolly CJ, 2018, 'SAMHD1 enhances immunoglobulin hypermutation by promoting transversion mutation', Proceedings of the National Academy of Sciences of the United States of America, vol. 115, pp. 4921 - 4926, http://dx.doi.org/10.1073/pnas.1719771115
2018
Roediger B; Lee Q; Tikoo S; Cobbin JCA; Henderson JM; Jormakka M; O'Rourke MB; Padula MP; Pinello N; Henry M; Wynne M; Santagostino SF; Brayton CF; Rasmussen L; Lisowski L; Tay SS; Harris DC; Bertram JF; Dowling JP; Bertolino P; Lai JH; Wu W; Bachovchin WW; Wong JJL; Gorrell MD; Shaban B; Holmes EC; Jolly CJ; Monette S; Weninger W, 2018, 'An Atypical Parvovirus Drives Chronic Tubulointerstitial Nephropathy and Kidney Fibrosis', Cell, vol. 175, pp. 530 - 543.e24, http://dx.doi.org/10.1016/j.cell.2018.08.013
2018
Jolly C; Gall M; Gorrell M; Cook A; Roediger B; Zhang HE; McCaughan G, 2018, 'Immune regeneration in irradiated mice is not impaired by the absence of DPP9 enzymatic activity [forthcoming publication]', Forthcoming/preprint available in bioRxiv, http://dx.doi.org/10.1101/431775
2018
Wang XM; Holz LE; Chowdhury S; Cordoba SP; Evans KA; Gall MG; De Ribeiro AJV; Zheng YZ; Levy MT; Yu DMT; Yao TW; Polak N; Jolly CJ; Bertolino P; McCaughan GW; Gorrell MD, 2017, 'The pro-fibrotic role of dipeptidyl peptidase 4 in carbon tetrachloride-induced experimental liver injury', Immunology and Cell Biology, vol. 95, pp. 443 - 453, http://dx.doi.org/10.1038/icb.2016.116
2017
Thientosapol ES; Sharbeen G; Edwin Lau KK; Bosnjak D; Durack T; Stevanovski I; Weninger W; Jolly CJ, 2017, 'Proximity to AGCT sequences dictates MMR-independent versus MMR-dependent mechanisms for AID-induced mutation via UNG2', Nucleic Acids Research, vol. 45, pp. 3146 - 3157, http://dx.doi.org/10.1093/nar/gkw1300
2017
Chang GH; Lay AJ; Ting KK; Zhao Y; Coleman PR; Powter EE; Formaz-Preston A; Jolly CJ; Bower NI; Hogan BM; Rinkwitz S; Becker TS; Vadas MA; Gamble JR, 2014, 'Arhgap18: An endogenous inhibitor of angiogenesis, limiting tip formation and stabilizing junctions', Small GTPases, vol. 5, pp. 1 - 15, http://dx.doi.org/10.4161/21541248.2014.975002
2014
Chan TD; Wood K; Hermes JR; Jolly CJ; Basten A; Brink R, 2012, 'Elimination of germinal-center-derived self-reactive B cells is governed by the location and concentration of self-antigen', Immunity, vol. 37, pp. 893 - 904, http://dx.doi.org/10.1016/j.immuni.2012.07.017
2012
Sharbeen G; Yee CWY; Smith AL; Jolly CJ, 2012, 'Ectopic restriction of DNA repair reveals that UNG2 excises AID-induced uracils predominantly or exclusively during G1 phase', Journal of Experimental Medicine, vol. 209, pp. 965 - 974, http://dx.doi.org/10.1084/jem.20112379
2012
Sharbeen G; Cook AJL; Lau KKE; Raftery J; Yee CWY; Jolly CJ, 2010, 'Incorporation of dUTP does not mediate mutation of A:T base pairs in Ig genes in vivo', Nucleic Acids Research, vol. 38, pp. 8120 - 8130, http://dx.doi.org/10.1093/nar/gkq682
2010
Jolly CJ; Cook AJL; Manis JP, 2008, 'Fixing DNA breaks during class switch recombination', Journal of Experimental Medicine, vol. 205, pp. 509 - 513, http://dx.doi.org/10.1084/jem.20080356
2008
Jolly C; Cook AJL; Raferty J; Jones ME, 2007, 'Measuring bidirectional mutation', Journal of Theoretical Biology, vol. 246, pp. 269 - 277, http://dx.doi.org/10.1016/j.jtbi.2006.12.034
2007
Jolly C; Cook AJL; Raftery J; Jones ME, 2007, 'Corrigendum to "Measuring bidirectional mutation". [J. Theor. Biol. 246 (2006) 269-277] (DOI:10.1016/j.jtbi.2006.12.034)', Journal of Theoretical Biology, vol. 247, pp. 862, http://dx.doi.org/10.1016/j.jtbi.2007.05.027
2007
Cook AJL; Raftery JM; Lau KKE; Jessup A; Harris RS; Takeda S; Jolly CJ, 2007, 'DNA-dependent protein kinase inhibits AID-induced antibody gene conversion', PLoS Biology, vol. 5, pp. 792 - 799, http://dx.doi.org/10.1371/journal.pbio.0050080
2007
Cook AJL; Oganesian L; Harumal P; Basten A; Brink R; Jolly CJ, 2003, 'Reduced Switching in SCID B Cells Is Associated with Altered Somatic Mutation of Recombined S Regions', Journal of Immunology, vol. 171, pp. 6556 - 6564, http://dx.doi.org/10.4049/jimmunol.171.12.6556
2003
Jolly CJ; Neuberger MS, 2001, 'Somatic hypermutation of immunoglobulin κ transgenes: Association of mutability with demethylation', Immunology and Cell Biology, vol. 79, pp. 18 - 22, http://dx.doi.org/10.1046/j.1440-1711.2001.00968.x
2001
Williams GT; Jolly CJ; Köhler J; Neuberger MS, 2000, 'The contribution of somatic hypermutation to the diversity of serum immunoglobulin: Dramatic increase with age', Immunity, vol. 13, pp. 409 - 417, http://dx.doi.org/10.1016/S1074-7613(00)00040-6
2000
Neuberger MS; Sale JE; Cumbers SJ; Jolly CJ; Bemark MP; Ehrenstein MR; Lanoue A; Brüggemann M; Batista FD; Davies SL; Williams GT, 2000, 'Diversification and selection mechanisms for the production of protein repertoires: Lessons from the immune system', Applied Biochemistry and Biotechnology - Part A Enzyme Engineering and Biotechnology, vol. 83, pp. 53 - 62, http://dx.doi.org/10.1385/ABAB:83:1-3:53
2000
Neuberger MS; Ehrenstein MR; Klix N; Jolly CJ; Yélamos J; Rada C; Milstein C, 1998, 'Monitoring and interpreting the intrinsic features of somatic hypermutation', Immunological Reviews, vol. 162, pp. 107 - 116, http://dx.doi.org/10.1111/j.1600-065X.1998.tb01434.x
1998
Klix N; Jolly CJ; Davies SL; Brüggemann M; Williams GT; Neuberger MS, 1998, 'Multiple sequences from downstream of the J(κ) cluster can combine to recruit somatic hypermutation to a heterologous, upstream mutation domain', European Journal of Immunology, vol. 28, pp. 317 - 326, http://dx.doi.org/10.1002/(SICI)1521-4141(199801)28:01<317::AID-IMMU317>3.0.CO;2-S
1998
Jolly CJ; Klix N; Neuberger MS, 1997, 'Rapid methods for the analysis of immunoglobulin gene hypermutation: Application to transgenic and gene targeted mice', Nucleic Acids Research, vol. 25, pp. 1913 - 1919, http://dx.doi.org/10.1093/nar/25.10.1913
1997
Jolly CJ; O'Neill HC, 1997, 'Specific transcription of the unrearranged TCR Vβ8.2 gene in lymphoid tissues occurs independently of V(D)J rearrangement', Immunology and Cell Biology, vol. 75, pp. 13 - 20, http://dx.doi.org/10.1038/icb.1997.3
1997
Jolly CJ; Wagner SD; Rada C; Klix N; Milstein C; Neuberger MS, 1996, 'The targeting of somatic hypermutation', Seminars in Immunology, vol. 8, pp. 159 - 168, http://dx.doi.org/10.1006/smim.1996.0020
1996
Jolly CJ; Glenn GM; Rahman S, 1996, 'GSP-1 genes are linked to the grain hardness locus (Ha) on wheat chromosome 5D', Proceedings of the National Academy of Sciences of the United States of America, vol. 93, pp. 2408 - 2413, http://dx.doi.org/10.1073/pnas.93.6.2408
1996
Jolly CJ; O'neill HC, 1995, 'Expression of a TCR Vβ8.2 polypeptide from the unrearranged gene in a murine lymphoid precursor cell line', International Immunology, vol. 7, pp. 1147 - 1156, http://dx.doi.org/10.1093/intimm/7.7.1147
1995
O'Neill HC; Jolly CJ, 1995, 'Germline transcription and expression of Tcrb-V8 genes in peripheral mouse lymphoid tissues', Immunogenetics, vol. 42, pp. 309 - 314, http://dx.doi.org/10.1007/BF00179391
1995
Ho ESP; Jolly CJ; O'Neill HC, 1994, 'Analysis of oncogenic progression in a radiation leukemia virus model', Leukemia, vol. 8, pp. 1202 - 1213
1994
RAHMAN S; JOLLY CJ; SKERRITT JH; WALLOSHECK A, 1994, 'Cloning of a wheat 15‐kDa grain softness protein (GSP): GSP is a mixture of puroindoline‐like polypeptides', European Journal of Biochemistry, vol. 223, pp. 917 - 925, http://dx.doi.org/10.1111/j.1432-1033.1994.tb19069.x
1994
Jolly CJ; Rahman S; Kortt AA; Higgins TJV, 1993, 'Characterisation of the wheat Mr 15000 "grain-softness protein" and analysis of the relationship between its accumulation in the whole seed and grain softness', Theoretical and Applied Genetics, vol. 86, pp. 589 - 597, http://dx.doi.org/10.1007/BF00838714
1993
O'Neill HC; Jolly C, 1992, 'Retroviral superantigens', Immunology Today, vol. 13, pp. 462 - 463, http://dx.doi.org/10.1016/0167-5699(92)90078-L
1992
Jolly CJ; Reid JB; Ross JJ, 1987, 'Internode length in Pisum. Action of gene lw', Physiologia Plantarum, vol. 69, pp. 489 - 498, http://dx.doi.org/10.1111/j.1399-3054.1987.tb09230.x
1987
Jolly CJ; Lee Q; Padula MP; Pinello N; Williams SH; O’Rourke MB; Fumagalli MJ; Orkin JD; Shaban B; Brenner O; Weninger W; de Souza WM; Melin AD; Wong JJ-L; Crim MJ; Monette S; Roediger B, 'MKPV (aka MuCPV) and related chapparvoviruses are nephro-tropic and encode novel accessory proteins p15 and NS2', , http://dx.doi.org/10.1101/732537
Conference Papers
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Jolly C; Sharbeen G; Yee C; Smith A, 2012, 'Processing of AID-induced uracils in distinct cell cycle phases', in JOURNAL OF IMMUNOLOGY, AMER ASSOC IMMUNOLOGISTS, Boston, MA, presented at 99th Annual Meeting of the American-Association-of-Immunologists, Boston, MA, 04 May 2012 - 08 May 2012
2012
Sale JE; Bemark M; Williams GT; Jolly CJ; Ehrenstein MR; Rada C; Milstein C; Neuberger MS, 2001, 'In vivo and in vitro studies of immunoglobulin gene somatic hypermutation', in Philosophical Transactions of the Royal Society B: Biological Sciences, ROYAL SOC, ROYAL SOC, LONDON, ENGLAND, pp. 21 - 28, presented at Discussion Meeting on Hypermutation in Antibody Genes, ROYAL SOC, LONDON, ENGLAND, 05 July 2000 - 06 July 2000, http://dx.doi.org/10.1098/rstb.2000.0744
2001
Jolly C; Kohonen-Corish M; Hodgkin P; Deenick E, 2000, 'MSH2-deficiency reduces the rate of switching to all mouse isotypes without altering the regulation of switching by cell division number', in FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, pp. A1046 - A1046
2000