Chandana Herath

Senior Lecturer

Dr Chandana B. Herath is an expert Hepatologist and Senior Lecturer of South Western Sydney Clinical School of the Faculty of Medicine and Health at University of New South Wales, Australia. He is also an honorary Senior Research Fellow at the Department of Medicine of the University of Melbourne at Austin Health, Melbourne where he is also supervising postdoctoral fellows working on research projects. Dr Herath has also been appointed as a professor (adjunct) with National Institute of Fundamental Studies in Kandy, Sri Lanka. During his career as a hepatologist he has made a significant contribution towards his discipline including developing animal models of liver diseases to study and formulate therapies to treat patients with liver diseases. Dr Herath is running a successful experimental gene therapy program targeting the renin angiotensin system in liver disease and has undertaken translational studies in humanised mouse models to test a novel human-liver specific viral vectors to be utilised for future clinical trials. He also leads a drug discovery program to design and develop novel therapeutics to treat portal hypertension in cirrhosis. He was successful in securing nationally competitive grant funding, amounting to over AU$ 3 million from the National Health and Medical Research Council of Australia. He has supervised and/or mentored 10 PhD and 4 MD students to successful completion and currently supervises postdoctoral fellows and research assistants working in a number of projects. Dr Herath has authored over 100 publications which include over 50 peer reviewed original papers, and reviews, book chapters, editorials and conference proceedings, and currently serving on the editorial boards of international scientific journals.

Journal articles
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Rajapaksha IG; Gunarathne LS; Asadi K; Laybutt R; Andrikopoulous S; Alexander IE; Watt MJ; Angus PW; Herath CB, 2022, 'Angiotensin Converting Enzyme-2 Therapy Improves Liver Fibrosis and Glycemic Control in Diabetic Mice With Fatty Liver', Hepatology Communications, vol. 6, pp. 1056 - 1072, http://dx.doi.org/10.1002/hep4.1884
2022
Gunarathne LS; Rajapaksha IG; Casey S; Qaradakhi T; Zulli A; Rajapaksha H; Trebicka J; Angus PW; Herath CB, 2022, 'Mas-related G protein-coupled receptor type D antagonism improves portal hypertension in cirrhotic rats', Hepatology Communications, http://dx.doi.org/10.1002/hep4.1987
2022
Herath CB; Angus PW; Trebicka J, 2022, 'Editorial: Portal Hypertension in Cirrhosis: From Pathogenesis to Novel Treatments', Frontiers in Physiology, vol. 13, http://dx.doi.org/10.3389/fphys.2022.864083
2022
Rajapaksha IG; Gunarathne LS; Angus PW; Herath CB, 2021, 'Update on new aspects of the renin-angiotensin system in hepatic fibrosis and portal hypertension: Implications for novel therapeutic options', Journal of Clinical Medicine, vol. 10, pp. 1 - 20, http://dx.doi.org/10.3390/jcm10040702
2021
Bogahawaththa S; Kodithuwakku SP; Wijesundera KK; Siriweera EH; Jayasinghe L; Dissanayaka WL; Rajapakse J; Herath CB; Tsujita T; Wijayagunawardane MPB, 2021, 'Anti-fibrotic and anti-angiogenic activities of osbeckia octandra leaf extracts in thioacetamide-induced experimental liver cirrhosis', Molecules, vol. 26, http://dx.doi.org/10.3390/molecules26164836
2021
Gunarathne L; Rajapaksha H; Shackel N; Angus P; Herath C, 2020, 'Cirrhotic portal hypertension: From pathophysiology to novel therapeutics', World Journal of Gastroenterology
2020
Warner FJ; Rajapaksha H; Shackel N; Herath CB, 2020, 'ACE2: From protection of liver disease to propagation of COVID-19', Clinical Science, vol. 134, pp. 3137 - 3158, http://dx.doi.org/10.1042/CS20201268
2020
Gunarathne LS; Angus PW; Herath CB, 2019, 'Blockade of Mas Receptor or Mas-Related G-Protein Coupled Receptor Type D Reduces Portal Pressure in Cirrhotic but Not in Non-cirrhotic Portal Hypertensive Rats', Front Physiol, vol. 10, pp. 1169, http://dx.doi.org/10.3389/fphys.2019.01169
2019
Rajapaksha IG; Gunarathne LS; Asadi K; Cunningham SC; Sharland A; Alexander IE; Angus PW; Herath CB, 2019, 'Liver-Targeted Angiotensin Converting Enzyme 2 Therapy Inhibits Chronic Biliary Fibrosis in Multiple Drug-Resistant Gene 2-Knockout Mice', Hepatol Commun, vol. 3, pp. 1656 - 1673, http://dx.doi.org/10.1002/hep4.1434
2019
Fernando DH; Forbes JM; Angus PW; Herath CB, 2019, 'Development and Progression of Non-Alcoholic Fatty Liver Disease: The Role of Advanced Glycation End Products', Int J Mol Sci, vol. 20, pp. 5037 - 5037, http://dx.doi.org/10.3390/ijms20205037
2019
Casey S; Schierwagen R; Mak KY; Klein S; Uschner F; Jansen C; Praktiknjo M; Meyer C; Thomas D; Herath C; Jones R; Trebicka J; Angus P, 2019, 'Activation of the Alternate Renin-Angiotensin System Correlates with the Clinical Status in Human Cirrhosis and Corrects Post Liver Transplantation', J Clin Med, vol. 8, http://dx.doi.org/10.3390/jcm8040419
2019
Alamri AS; Brock JA; Herath CB; Rajapaksha IG; Angus PW; Ivanusic JJ, 2019, 'The Effects of Diabetes and High-Fat Diet on Polymodal Nociceptor and Cold Thermoreceptor Nerve Terminal Endings in the Corneal Epithelium', Invest Ophthalmol Vis Sci, vol. 60, pp. 209 - 217, http://dx.doi.org/10.1167/iovs.18-25788
2019
Rajapaksha IG; Angus PW; Herath CB, 2019, 'Current therapies and novel approaches for biliary diseases', World J Gastrointest Pathophysiol, vol. 10, pp. 1 - 10, http://dx.doi.org/10.4291/wjgp.v10.i1.1
2019
Fernando HKDH; Leung C; Angus P; Herath C, 2019, 'Advanced glycation end products (AGEs) exacerbate NAFLD progression to liver fibrosis via receptor for AGEs (RAGE) in high fat fed mice', JOURNAL OF HEPATOLOGY, vol. 70, pp. E525 - E525, http://dx.doi.org/10.1016/S0618-8278(19)31039-4
2019
Fernando HKDH; Leung C; Angus P; Herath C, 2019, 'SAT-343-Alagebrium ameliorates NAFLD progression in mice fed a high advanced glycation end products diet via direct inhibition of Kupffer cells and indirect inhibition of hepatic stellate cell activation', Journal of Hepatology, vol. 70, pp. e789 - e790, http://dx.doi.org/10.1016/s0618-8278(19)31573-7
2019
Gunarathne L; Zulli A; Qaradakhi T; Smith R; Tacey AB; Angus P; Herath C, 2018, 'Mas-related G-protein coupled receptor type D (MrgD) antagonism produces splanchnic vasculature-specific effects, leading to a large reduction in portal pressure in cirrhotic animals', JOURNAL OF HEPATOLOGY, vol. 68, pp. S117 - S117, http://dx.doi.org/10.1016/S0168-8278(18)30449-5
2018
Rajapaksha IG; Mak KY; Huang P; Burrell LM; Angus PW; Herath CB, 2018, 'The small molecule drug diminazene aceturate inhibits liver injury and biliary fibrosis in mice', Sci Rep, vol. 8, pp. 10175, http://dx.doi.org/10.1038/s41598-018-28490-y
2018
Casey S; Herath C; Rajapaksha I; Jones R; Angus P, 2018, 'Effects of angiotensin-(1-7) and angiotensin II on vascular tone in human cirrhotic splanchnic vessels', Peptides, vol. 108, pp. 25 - 33, http://dx.doi.org/10.1016/j.peptides.2018.08.008
2018
Mak KY; Rajapaksha IG; Angus PW; Herath CB, 2017, 'The Adeno-associated Virus - A Safe and Promising Vehicle for Liverspecific Gene Therapy of Inherited and Non-inherited Disorders', Curr Gene Ther, vol. 17, pp. 4 - 16, http://dx.doi.org/10.2174/1566523217666170314141931
2017
Zhuang A; Yap FY; Bruce C; Leung C; Plan MR; Sullivan MA; Herath C; McCarthy D; Sourris KC; Kantharidis P; Coughlan MT; Febbraio MA; Hodson MP; Watt MJ; Angus P; Schulz BL; Forbes JM, 2017, 'Increased liver AGEs induce hepatic injury mediated through an OST48 pathway', Sci Rep, vol. 7, pp. 12292, http://dx.doi.org/10.1038/s41598-017-12548-4
2017
Casey S; Mak K; Lumsden N; Herath C; Kaye D; Chin-Dusting J; Angus P, 2017, 'The alternate renin angiotensin system is upregulated and Ang-(1-7) mediates vasodilatation in human cirrhosis', JOURNAL OF HEPATOLOGY, vol. 66, pp. S579 - S580, http://dx.doi.org/10.1016/S0168-8278(17)31582-9
2017
Rajapaksha IG; Mak KY; Angus PW; Herath CB, 2017, 'ACE2 therapy using a liver-specific AAV vector inhibits chronic biliary fibrosis in mice', JOURNAL OF HEPATOLOGY, vol. 66, pp. S366 - S366, http://dx.doi.org/10.1016/S0168-8278(17)31074-7
2017
Leung C; Herath CB; Jia Z; Andrikopoulos S; Brown BE; Davies MJ; Rivera LR; Furness JB; Forbes JM; Angus PW, 2016, 'Dietary advanced glycation end-products aggravate non-alcoholic fatty liver disease', World J Gastroenterol, vol. 22, pp. 8026 - 8040, http://dx.doi.org/10.3748/wjg.v22.i35.8026
2016
Wijayagunawardane MP; Hambruch N; Haeger JD; Pfarrer C, 2015, 'Effect of epidermal growth factor (EGF) on the phosphorylation of mitogen-activated protein kinase (MAPK) in the bovine oviduct in vitro: Alteration by heat stress', J Reprod Dev, vol. 61, pp. 383 - 389, http://dx.doi.org/10.1262/jrd.2014-061
2015
Alsaadon H; Kruzliak P; Smardencas A; Hayes A; Bader M; Angus P; Herath C; Zulli A, 2015, 'Increased aortic intimal proliferation due to MasR deletion in vitro', Int J Exp Pathol, vol. 96, pp. 183 - 187, http://dx.doi.org/10.1111/iep.12118
2015
Wijayagunawardane MPB; Wijerathne CUB; Herath CB, 2015, 'Indigenous Herbal Recipes for Treatment of Liver Cirrhosis', 2ND HUMBOLDT KOLLEG IN CONJUNCTION WITH INTERNATIONAL CONFERENCE ON NATURAL SCIENCES 2014, HK-ICONS 2014, vol. 14, pp. 270 - 276, http://dx.doi.org/10.1016/j.proche.2015.03.038
2015
Mak KY; Chin R; Cunningham SC; Habib MR; Torresi J; Sharland AF; Alexander IE; Angus PW; Herath CB, 2015, 'ACE2 Therapy Using Adeno-associated Viral Vector Inhibits Liver Fibrosis in Mice', Mol Ther, vol. 23, pp. 1434 - 1443, http://dx.doi.org/10.1038/mt.2015.92
2015
Klein S; Herath CB; Schierwagen R; Grace J; Haltenhof T; Uschner FE; Strassburg CP; Sauerbruch T; Walther T; Angus PW; Trebicka J, 2015, 'Hemodynamic effects of the non-peptidic angiotensin-(1-7) agonist AVE0991 in liver cirrhosis', PLoS ONE, vol. 10, http://dx.doi.org/10.1371/journal.pone.0138732
2015
Rivera LR; Leung C; Pustovit RV; Hunne BL; Andrikopoulos S; Herath C; Testro A; Angus PW; Furness JB, 2014, 'Damage to enteric neurons occurs in mice that develop fatty liver disease but not diabetes in response to a high-fat diet', Neurogastroenterol Motil, vol. 26, pp. 1188 - 1199, http://dx.doi.org/10.1111/nmo.12385
2014
Leung C; Herath CB; Jia Z; Goodwin M; Mak K; Watt MJ; Forbes JM; Angus PW, 2014, 'DIETARY GLYCOTOXINS EXACERBATE PROGRESSION OF EXPERIMENTAL FATTY LIVER DISEASE', JOURNAL OF HEPATOLOGY, vol. 60, pp. S155 - S155, http://dx.doi.org/10.1016/S0168-8278(14)60434-7
2014
Leung C; Herath CB; Jia Z; Goodwin M; Mak KY; Watt MJ; Forbes JM; Angus PW, 2014, 'Dietary glycotoxins exacerbate progression of experimental fatty liver disease', J Hepatol, vol. 60, pp. 832 - 838, http://dx.doi.org/10.1016/j.jhep.2013.11.033
2014
Mak KY; Chin R; Torresi J; Cunningham SC; Alexander IE; Angus PW; Herath CB, 2014, 'ANGIOTENSIN CONVERTING ENZYME 2 (ACE2) GENE THERAPY USING A HIGH EFFICIENCY AND LIVER-SPECIFIC ADENO-ASSOCIATED VIRAL VECTOR ATTENUATES EXPERIMENTAL LIVER FIBROSIS IN MICE', JOURNAL OF HEPATOLOGY, vol. 60, pp. S268 - S269, http://dx.doi.org/10.1016/S0168-8278(14)60760-1
2014
Herath CB; Mak K; Burrell LM; Angus PW, 2013, 'Angiotensin-(1-7) reduces the perfusion pressure response to angiotensin II and methoxamine via an endothelial nitric oxide-mediated pathway in cirrhotic rat liver', Am J Physiol Gastrointest Liver Physiol, vol. 304, pp. G99 - 108, http://dx.doi.org/10.1152/ajpgi.00163.2012
2013
Goodwin M; Herath C; Jia Z; Leung C; Coughlan MT; Forbes J; Angus P, 2013, 'Advanced glycation end products augment experimental hepatic fibrosis', Journal of Gastroenterology and Hepatology, vol. 28, pp. 369 - 376, http://dx.doi.org/10.1111/jgh.12042
2013
Herath CB; Grace JA; Angus PW, 2013, 'Therapeutic potential of targeting the renin angiotensin system in portal hypertension', World J Gastrointest Pathophysiol, vol. 4, pp. 1 - 11, http://dx.doi.org/10.4291/wjgp.v4.i1.1
2013
Klein S; Grace J; Granzow M; Schierwagen R; Masing N; Herath C; Burell L; Angus P; Sauerbruch T; Trebicka J, 2013, 'Intramural gebildetes Angiotensin 1–7 bewirkt eine splanchnische Vasodilatation via Mas-Rezeptor Stimulierung und induziert dadurch eine vaskuläre Dysfunktion in der Leberzirrhose', Zeitschrift für Gastroenterologie, vol. 51, http://dx.doi.org/10.1055/s-0032-1331926
2013
Grace JA; Klein S; Herath CB; Granzow M; Schierwagen R; Masing N; Walther T; Sauerbruch T; Burrell LM; Angus PW; Trebicka J, 2013, 'Activation of the MAS receptor by angiotensin-(1-7) in the renin-angiotensin system mediates mesenteric vasodilatation in cirrhosis', Gastroenterology, vol. 145, pp. 874-884 e5, http://dx.doi.org/10.1053/j.gastro.2013.06.036
2013
Yeung LW; Guruge KS; Taniyasu S; Yamashita N; Angus PW; Herath CB, 2013, 'Profiles of perfluoroalkyl substances in the liver and serum of patients with liver cancer and cirrhosis in Australia', Ecotoxicol Environ Saf, vol. 96, pp. 139 - 146, http://dx.doi.org/10.1016/j.ecoenv.2013.06.006
2013
Grace JA; Herath CB; Mak KY; Burrell LM; Angus PW, 2012, 'Update on new aspects of the renin-angiotensin system in liver disease: clinical implications and new therapeutic options', Clin Sci (Lond), vol. 123, pp. 225 - 239, http://dx.doi.org/10.1042/CS20120030
2012
Garg M; Angus PW; Burrell LM; Herath C; Gibson PR; Lubel JS, 2012, 'Review article: the pathophysiological roles of the renin-angiotensin system in the gastrointestinal tract', Aliment Pharmacol Ther, vol. 35, pp. 414 - 428, http://dx.doi.org/10.1111/j.1365-2036.2011.04971.x
2012
Sugawara K; Kizaki K; Herath CB; Hasegawa Y; Hashizume K, 2010, 'Transforming growth factor beta family expression at the bovine feto-maternal interface', Reprod Biol Endocrinol, vol. 8, pp. 120, http://dx.doi.org/10.1186/1477-7827-8-120
2010
Neo JH; Ager EI; Angus PW; Zhu J; Herath CB; Christophi C, 2010, 'Changes in the renin angiotensin system during the development of colorectal cancer liver metastases', BMC Cancer, vol. 10, pp. 134, http://dx.doi.org/10.1186/1471-2407-10-134
2010
Lubel JS; Herath CB; Tchongue J; Grace J; Jia Z; Spencer K; Casley D; Crowley P; Sievert W; Burrell LM; Angus PW, 2009, 'Angiotensin-(1-7), an alternative metabolite of the renin-angiotensin system, is up-regulated in human liver disease and has antifibrotic activity in the bile-duct-ligated rat', Clin Sci (Lond), vol. 117, pp. 375 - 386, http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=19371232
2009
Herath CB; Lubel JS; Jia Z; Velkoska E; Casley D; Brown L; Tikellis C; Burrell LM; Angus PW, 2009, 'Portal pressure responses and angiotensin peptide production in rat liver are determined by relative activity of ACE and ACE2', Am J Physiol Gastrointest Liver Physiol, vol. 297, pp. G98 - G106, http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=19389807
2009
Kemp W; Kompa A; Phrommintikul A; Herath C; Zhiyuan J; Angus P; McLean C; Roberts S; Krum H, 2009, 'Urotensin II modulates hepatic fibrosis and portal hemodynamic alterations in rats', Am J Physiol Gastrointest Liver Physiol, vol. 297, pp. G762 - G767, http://dx.doi.org/10.1152/ajpgi.00127.2009
2009
Lubel JS; Herath CB; Jia Z; Tchongue J; Sievert W; Burrell LM; Angus RW, 2008, 'New insights into the angiotensin 1-7/MAS receptor interaction from a murine model of hepatic fibrosis and hepatic stellate cell culture', JOURNAL OF HEPATOLOGY, vol. 48, pp. S182 - S182, http://dx.doi.org/10.1016/S0168-8278(08)60480-8
2008
Lubel JS; Herath CB; Burrell LM; Angus PW, 2008, 'Liver disease and the renin-angiotensin system: Recent discoveries and clinical implications', J Gastroenterol Hepatol, vol. 23, pp. 1327 - 1338, http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18557800
2008
Lubel JS; Herath CB; Velkoska E; Casley DJ; Burrell LM; Angus PW, 2008, 'Angiotensin converting enzyme 2 (ACE2) activity in fetal calf serum: implications for cell culture research', Cytotechnology, vol. 58, pp. 119 - 126, http://dx.doi.org/10.1007/s10616-009-9185-0
2008
Herath CB; Warner FJ; Lubel JS; Dean RG; Jia Z; Lew RA; Smith AI; Burrell LM; Angus PW, 2007, 'Upregulation of hepatic angiotensin-converting enzyme 2 (ACE2) and angiotensin-(1-7) levels in experimental biliary fibrosis', J Hepatol, vol. 47, pp. 387 - 395, http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17532087
2007
Herath CB; Ishiwata H; Shiojima S; Kadowaki T; Katsuma S; Ushizawa K; Imai K; Takahashi T; Hirasawa A; Takahashi S; Izaike Y; Tsujimoto G; Hashizume K, 2006, 'Developmental aberrations of liver gene expression in bovine fetuses derived from somatic cell nuclear transplantation', Cloning Stem Cells, vol. 8, pp. 79 - 95, http://dx.doi.org/10.1089/clo.2006.8.79
2006
Herath CB; Shiojima S; Ishiwata H; Katsuma S; Kadowaki T; Ushizawa K; Imai K; Takahashi T; Hirasawa A; Tsujimoto G; Hashizume K, 2004, 'Pregnancy-associated changes in genome-wide gene expression profiles in the liver of cow throughout pregnancy', Biochem Biophys Res Commun, vol. 313, pp. 666 - 680, http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=14697243
2004
Herath CB; Jin W; Watanabe G; Arai K; Suzuki AK; Taya K, 2004, 'Adverse effects of environmental toxicants, octylphenol and bisphenol A, on male reproductive functions in pubertal rats', Endocrine, vol. 25, pp. 163 - 172, http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15711031
2004
Ushizawa K; Herath CB; Kaneyama K; Shiojima S; Hirasawa A; Takahashi T; Imai K; Ochiai K; Tokunaga T; Tsunoda Y; Tsujimoto G; Hashizume K, 2004, 'cDNA microarray analysis of bovine embryo gene expression profiles during the pre-implantation period', Reprod Biol Endocrinol, vol. 2, pp. 77, http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=15560851
2004
Yamauchi N; Kizaki K; Yamada O; Takahashi T; Herath CB; Hashizume K, 2003, 'Expression of integrin subunits depend on bovine endometrial stromal cells cultured in vitro', Connective Tissue, vol. 35, pp. 1 - 7
2003
Yamauchi N; Takezawa T; Kizaki K; Herath CB; Hashizume K, 2003, 'Proliferative potential of endometrial stromal cells, and endometrial and placental expression of cyclin in the bovine', J Reprod Dev, vol. 49, pp. 553 - 560, http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=14967908
2003
Tanaka Y; Taniyama H; Tsunoda N; Herath CB; Nakai R; Shinbo H; Nagamine N; Nambo Y; Nagata S; Watanabe G; Groome NP; Taya K, 2003, 'Localization and secretion of inhibins in the equine fetal ovaries', Biol Reprod, vol. 68, pp. 328 - 335, http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=12493730
2003
Tanaka Y; Taniyama H; Tsunoda N; Shinbo H; Nagamine N; Nambo Y; Nagata S; Watanabe G; Herath CB; Groome NP; Taya K, 2002, 'The testis as a major source of circulating inhibins in the male equine fetus during the second half of gestation', J Androl, vol. 23, pp. 229 - 236, http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11868816
2002
Jin W; Herath CB; Yoshida M; Arai KY; Saita E; Zhanquan S; Ren L; Watanabe G; Groome NP; Taya K, 2002, 'Inhibin B regulating follicle-stimulating hormone secretion during testicular recrudescence in the male golden hamster', J Androl, vol. 23, pp. 845 - 853, http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=12399532
2002
Shi F; Petroff BK; Herath CB; Ozawa M; Watanabe G; Taya K, 2002, 'Serous cysts are a benign component of the cyclic ovary in the guinea pig with an incidence dependent upon inhibin bioactivity', J Vet Med Sci, vol. 64, pp. 129 - 135, http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11913549
2002
Jin W; Wada S; Arai KY; Kishi H; Herath CB; Watanabe G; Suzuki AK; Groome NP; Taya K, 2001, 'Testicular secretion of inhibin in the male golden hamster (Mesocricetus auratus)', J Androl, vol. 22, pp. 207 - 211, http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11229794
2001
Herath CB; Watanabe G; Wanzhu J; Noguchi J; Akiyama K; Kuramoto K; Groome NP; Taya K, 2001, 'Elevated levels of inhibin-A and immunoreactive inhibin in aged male Wistar rats with testicular Leydig cell tumor', J Androl, vol. 22, pp. 838 - 846, http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11545298
2001
Herath CB; Yamashita M; Watanabe G; Jin W; Tangtrongsup S; Kojima A; Groome NP; Suzuki AK; Taya K, 2001, 'Regulation of follicle-stimulating hormone secretion by estradiol and dimeric inhibins in the infantile female rat', Biol Reprod, vol. 65, pp. 1623 - 1633, http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11717121
2001
Wang H; Herath CB; Xia G; Watanabe G; Taya K, 2001, 'Superovulation, fertilization and in vitro embryo development in mice after administration of an inhibin-neutralizing antiserum', Reproduction, vol. 122, pp. 809 - 816, http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11690542
2001
Kondo M; Udono T; Jin WZ; Funakoshi M; Shimizu K; Itoh M; Herath CB; Watanabe G; Groome NP; Taya K, 2001, 'Secretion of inhibin A and inhibin B throughout pregnancy and the early postpartum period in chimpanzees', J Endocrinol, vol. 168, pp. 257 - 262, http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11182763
2001
Jin W; Arai KY; Herath CB; Kondo M; Ishi H; Tanioka Y; Watanabe G; Groome NP; Tayat K, 2001, 'Inhibins in the male Gottingen miniature pig: Leydig cells are the predominant source of inhibin B', J Androl, vol. 22, pp. 953 - 960, http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11700859
2001
Herath CB; Watanabe G; Katsuda S; Yoshida M; Suzuki AK; Taya K, 2001, 'Exposure of neonatal female rats to p-tert-octylphenol disrupts afternoon surges of luteinizing hormone, follicle-stimulating hormone and prolactin secretion, and interferes with sexual receptive behavior in adulthood', Biol Reprod, vol. 64, pp. 1216 - 1224, http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11259270
2001
Herath CB; Reynolds GW; MacKenzie DD; Davis SR; Harris PM, 1999, 'Vagotomy suppresses cephalic phase insulin release in sheep', Exp Physiol, vol. 84, pp. 559 - 569, http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=10362854
1999
Book Chapters
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Gunarathne LS; Rajapaksha H; Shackel N; Angus PW; Herath CB, 2021, 'Study On Cirrhotic Portal Hypertension: An Approach from Pathophysiology to Novel Therapeutics', in Highlights on Medicine and Medical Science Vol. 13, Book Publisher International (a part of SCIENCEDOMAIN International), pp. 61 - 100, http://dx.doi.org/10.9734/bpi/hmms/v13/9900d
2021
Fernando DH; Forbes J; Angus P; Herath CB, 2020, 'The Receptor for Advanced Glycation End Products (RAGE): A Potential Target for Therapeutic Intervention in the Progression of Non-Alcoholic Fatty Liver Disease (NAFLD)', in Zheng SG (ed.), Prime Archives in Molecular Biology, Vide Leaf Publishers, Hyderabad, India
2020
Herath C, 2018, 'Adeno-associated virus (AAV)-mediated gene therapy for disorders of inherited and non-inherited origin', in Bachtarzi H (ed.), Gene Therapy, IntechOpen Publishers
2018
Herath CB; Mak KY; Angus PW, 2015, 'Chapter 34 Role of the Alternate RAS in Liver Disease and the GI Tract', in The Protective Arm of the Renin Angiotensin System (RAS), pp. 239 - 247, http://dx.doi.org/10.1016/b978-0-12-801364-9.00034-1
2015
Herath CB; Mak K; Angus PW, 2015, 'Role of the alternate RAS in liver disease and the GI tract', in Unger T; Santos R (ed.), The Protective Arm of the Renin Angiotensin System (RAS) Functional Aspects and Therapeutic Implications, Elsevier Academic Press
2015
Conference Papers
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Fernando HKDH; Leung C; Angus P; Herath C, 2019, 'Alagebrium ameliorates NAFLD progression in mice fed a high advanced glycation end products diet via direct inhibition of Kupffer cells and indirect inhibition of hepatic stellate cell activation', in JOURNAL OF HEPATOLOGY, ELSEVIER, Vienna, AUSTRIA, pp. E789 - E790, presented at International Liver Congress / 54th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL), Vienna, AUSTRIA, 10 April 2019 - 14 April 2019, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000463481703330&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2019
Fernando HKDH; Rajapaksha DIG; Forbes JM; Angus PW; Herath CB, 2018, 'Dietary advanced glycation end products play a major role in exacerbating progression of non-alcoholic fatty liver disease to liver fibrosis in diabetic mice', in JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, WILEY, pp. 27 - 28, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000530647800044&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2018
Gunarathne LS; Zulli A; Qaradakhi T; Smith R; Tacey AB; Angus PW; Herath CB, 2018, 'Mas-related G protein-coupled receptor type D is a novel therapeutic target to reduce splanchnic vasodilatation in portal hypertension', in JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, WILEY, pp. 29 - 29, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000530647800046&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2018
Rajapaksha DIG; Gunarathne LS; Andrikopoulos S; Angus PW; Herath CB, 2017, 'Angiotensin converting enzyme 2-adeno-associated viral vector gene therapy ameliorates liver fibrosis in diabetic mice with non-alcoholic fatty liver disease', in JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, WILEY, pp. 11 - 11, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000407897100018&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2017
Fernando HKDH; Rajapaksha DIG; Angus PW; Herath CB, 2017, 'Alagebrium inhibits progression of non-alcoholic fatty liver disease to steatohepatitis and liver fibrosis by blocking AGE/RAGE pathway in mice', in JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, WILEY, pp. 5 - 5, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000407897100006&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2017
Gunarathne LS; Rajapaksha DIG; Fernando HKDH; Angus PW; Herath CB, 2017, 'Evolution of the renin angiotensin system in a rat model of non-cirrhotic portal hypertension', in JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, WILEY, pp. 5 - 6, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000407897100007&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2017
Herath C, 2016, 'Ace2 Gene Therapy Inhibits Chronic Biliary Fibrosis in Mice', in Qatar Foundation Annual Research Conference Proceedings Volume 2016 Issue 1, Hamad bin Khalifa University Press (HBKU Press), presented at Qatar Foundation Annual Research Conference Proceedings, http://dx.doi.org/10.5339/qfarc.2016.hbpp2549
2016
Mak KY; Chin R; Cunningham SC; Habib M; Torresi J; Sharland AF; Alexander IE; Angus PW; Herath CB, 2015, 'ANGIOTENSIN-CONVERTING ENZYME 2 GENE THERAPY USING A HIGH EFFICIENCY AND LIVER-SPECIFIC ADENO-ASSOCIATED VIRAL VECTOR ATTENUATES LIVER FIBROSIS IN MICE', in JOURNAL OF GENE MEDICINE, WILEY-BLACKWELL, Univ Melbourne, Univ Coll, Parkville, AUSTRALIA, pp. 205 - 206, presented at 9th Biennial Meeting of the Australasian-Gene-and-Cell-Therapy-Society (AGCTS), Univ Melbourne, Univ Coll, Parkville, AUSTRALIA, 29 April 2015 - 01 May 2015, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000362592700052&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2015
Rajapaksha IG; Mak KY; Cunningham SC; Torresi J; Sharland AF; Alexander IE; Angus PW; Herath CB, 2015, 'ACE2 gene therapy using adeno-associated viral vector inhibits biliary fibrosis in Mdr2-knockout mice', in HUMAN GENE THERAPY, MARY ANN LIEBERT, INC, Helsinki, FINLAND, pp. A104 - A105, presented at Collaborative Congress of the European-Society-of-Gene-and-Cell-Therapy (ESGCT) and Finnish-Society-of-Gene-Therapy (FSGT), Helsinki, FINLAND, 17 September 2015 - 20 September 2015, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000363878700324&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2015
Mak KY; Chin R; Torresi J; Cunningham S; Alexander I; Angus PW; Herath CB, 2014, 'Angiotensin converting enzyme 2 (ACE2) gene therapy using a high efficiency and liver-specific adeno-associated viral vector attenuates experimental liver fibrosis in mice', in JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, WILEY-BLACKWELL, pp. 4 - 4, http://dx.doi.org/10.1111/jgh.12736_9
2014
Leung C; Herath CB; Zhiyuan J; Leong T; Forbes JM; Angus PW, 2014, 'Manipulation of dietary advanced glycation end-product content influences the progression of non-alcoholic fatty liver disease (NAFLD)', in JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, WILEY-BLACKWELL, pp. 5 - 6, http://dx.doi.org/10.1111/jgh.12794
2014
Klein S; Herath CB; Uschner FE; Grace JA; Schierwagen R; Strassburg CP; Sauerbruch T; Angus PW; Trebicka J, 2014, 'Hemodynamic effects of the oral non peptide compound AVE0991', in HEPATOLOGY, WILEY-BLACKWELL, Boston, MA, pp. 1175A - 1175A, presented at 65th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases, Boston, MA, 07 November 2014 - 11 November 2014, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000344483805077&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2014
Leung C; Herath C; Jia Z; Goodwin M; Mak KY; Forbes JM; Angus P, 2012, 'Advanced glycosylation endproducts in nonalcoholic steatohepatitis: a second hit that drives hepatic stellate cell activation?', in JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, WILEY-BLACKWELL, pp. 9 - 9, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000308642600017&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2012
Klein S; Grace JA; Granzow M; Schierwagen R; Herath CB; Burrell LM; Angus PW; Sauerbruch T; Trebicka J, 2012, 'Intramural generated Angiotensin 1-7 mediates splanchnic vasodilation via mas-receptor stimulation and thereby vascular dysfunction in cirrhosis', in HEPATOLOGY, WILEY-BLACKWELL, Boston, MA, pp. 741A - 742A, presented at 63rd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD), Boston, MA, 09 November 2012 - 13 November 2012, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000310955602521&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2012
Grace JA; Herath CB; Jia Z; Burrell LM; Angus PW, 2011, 'INCREASED FORMATION OF SPLANCHNIC VASCULAR ANGIOTENSIN-(1-7) FROM ANGIOTENSIN I AND ANGIOTENSIN II IS MEDIATED BY ANGIOTENSIN CONVERTING ENZYME-2 IN EXPERIMENTAL CIRRHOSIS AND PORTAL HYPERTENSION', in HEPATOLOGY, WILEY-BLACKWELL, San Francisco, CA, pp. 948A - 948A, presented at 62nd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD), San Francisco, CA, 04 November 2011 - 08 November 2011, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000295578003467&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2011
Grace JA; Jia Z; Herath CB; Burrell LM; Angus PW, 2011, 'Increased formation of splanchnic vascular angiotensin-(1-7) from angiotensin I and angiotensin II is mediated by angiotensin converting enzyme-2 in experimental cirrhosis and portal hypertension', in JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, WILEY-BLACKWELL, pp. 4 - 4, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000295157300009&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2011
Leung C; Herath CB; Zhiyuan J; Goodwin M; Mak KY; Morley A; Nguyen VT; Forbes JM; Angus PW, 2011, 'Is our diet ageing us? How advanced glycation endproducts (ages) worsen fatty liver disease', in JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, WILEY-BLACKWELL, pp. 14 - 14, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000295157300037&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2011
Grace JA; Jia Z; Herath CB; Burrell LM; Angus PW, 2010, 'Angiotensin-(1-7) is a mesenteric vasodilator in experimental cirrhosis', in JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, WILEY-BLACKWELL PUBLISHING, INC, pp. A4 - A4, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000283321200007&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2010
Herath CB; Mak K; Jia Z; Burrell LM; Angus PW, 2010, 'Angiotensin-(1-7) reduces portal pressure via guanylate cyclase-dependent nitric oxide but angiotensin ii receptor independent pathway in cirrhotic rat liver', in JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, WILEY-BLACKWELL PUBLISHING, INC, pp. A14 - A14, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000283321200034&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2010
Goodwin M; Herath CB; Jia Z; Forbes JM; Angus PW, 2010, 'ADVANCED GLYCATION ENDPRODUCTS AUGMENT HEPATIC FIBROSIS IN AN EXPERIMENTAL MODEL OF CHRONIC LIVER DISEASE', in HEPATOLOGY, WILEY-BLACKWELL, Boston, MA, pp. 1278A - 1278A, presented at 61st Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases, Boston, MA, 29 October 2010 - 02 November 2010, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000288775602636&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2010
Grace JA; Jia Z; Herath CB; Burrell LM; Angus PW, 2010, 'ANGIOTENSIN-(1-7) IS A MESENTERIC VASODILATOR IN EXPERIMENTAL CIRRHOSIS', in HEPATOLOGY, WILEY-BLACKWELL, Boston, MA, pp. 1018A - 1019A, presented at 61st Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases, Boston, MA, 29 October 2010 - 02 November 2010, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000288775602074&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2010
Goodwin MA; Herath CB; Jia Z; Coughlan M; Forbes JM; Angus PW, 2009, 'The role of rage (receptor for advanced glycation endproducts) in hepatic fibrogenesis', in JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, WILEY-BLACKWELL PUBLISHING, INC, pp. A304 - A304, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000270551200229&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2009
Herath CB; Jia Z; Burrell LM; Angus PW, 2009, 'ANGIOTENSIN-(1-7) ATTENUATES ANGIOTENSIN II-INDUCED INCREASES IN HEPATIC RESISTANCE VIA NON-MAS RECEPTOR MEDIATED PATHWAY IN CIRRHOTIC RAT LIVER', in HEPATOLOGY, JOHN WILEY & SONS INC, Boston, MA, pp. 482A - 482A, presented at 60th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases, Boston, MA, 30 October 2009 - 03 November 2009, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000270456000377&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2009
Lubel JS; Herath C; Jia Z; Burrell LM; Angus P, 2008, 'Ang 1-7 fails to potentiate acetylcholine vasodilatation in the preconstricted in situ perfused cirrhotic rat liver', in GUT, B M J PUBLISHING GROUP, Brimingham, ENGLAND, pp. A82 - A82, presented at Annual General Meeting of the British-Society-of-Gastroenterology, Brimingham, ENGLAND, 10 March 2008 - 13 March 2008, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000253090600215&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2008
Clonan MA; Herath CB; Zhiyuan J; Forbes JM; Angus PW, 2008, 'The effects of advanced glycation end products on hepatic fibrogenesis', in JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, WILEY-BLACKWELL PUBLISHING, INC, pp. A261 - A261, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000259960100173&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2008
Herath CB; Lubel JS; Warner FJ; Jia Z; Dean RG; Lew RA; Smith IA; Burrell LM; Angus PW, 2007, 'Chronic liver injury is associated with the upregulation of the ACE2-angiotensin-(1-7)-Mas axis in the rat', in JOURNAL OF HEPATOLOGY, ELSEVIER SCIENCE BV, Barcelona, SPAIN, pp. S128 - S128, presented at 42th Annual Meeting of the European-Association-for-the-Study-of-the-Liver, Barcelona, SPAIN, 11 April 2007 - 15 April 2007, http://dx.doi.org/10.1016/S0168-8278(07)61924-2
2007
Lubel JS; Herath CB; Jia Z; Burrell LM; Angus PW, 2007, 'Angiotensin 1-7 reduces bile duct proliferation and hepatic fibrosis in the bile duct ligated rat', in HEPATOLOGY, JOHN WILEY & SONS INC, Boston, MA, pp. 706A - 707A, presented at 58th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases, Boston, MA, 02 November 2007 - 06 November 2007, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000249910401317&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2007
Lubel JS; Herath CB; Warner FJ; Jia ZY; Burrell LM; Angus PW, 2006, 'Upregulation of the ACE2/ANG1-7/MAS receptor axis in the bile duct ligation (BDL) model of hepatic fibrosis does not affect hepatic sinusoidal resistance', in JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, BLACKWELL PUBLISHING, pp. A332 - A332, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000247320600169&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2006
Herath CB; Warner FW; Lubel JS; Dean R; Lew R; Smith I; Burrell LM; Angus PW, 2006, 'The balance between hepatic ACE2 & ACE determines plasma levels of vasodilator peptide angiotensin-(1-7) in experimental biliary fibrosis', in JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, BLACKWELL PUBLISHING, pp. A325 - A325, http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000247320600156&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=891bb5ab6ba270e68a29b250adbe88d1
2006

Japan Society for the Promotion of Science (JSPS) postdoctoral Fellowship

Best Paper Prize from Australasian Gene and Cell Therapy Society (AGCTS) - 2018

Massey University PhD scholarships

Major Grant Funding:

● National Health and Medical Research Council (NHMRC) project grant (APP1124125): Novel therapies targeting the alternate renin angiotensin system in chronic liver disease (2017-2021; $1,284,565).

● National Health and Medical Research Council (NHMRC) project grant (APP1062372): The alternate renin angiotensin system; a novel target for the prevention and treatment of liver fibrosis and portal hypertension (2014-2016; $671,034).

● National Health and Medical Research Council (NHMRC) project grant (APP1029990): The AGE-RAGE pathway in chronic liver disease; a novel target for prevention and treatment (2012-2014; $446,175).

● National Health and Medical Research Council (NHMRC) project grant (APP1008252): Targeting the RAS in liver fibrosis and portal hypertension (2011-2013; $621,000).

● National Health and Medical Research Council (NHMRC) equipment grant: 2100 Bioanalyzer with Electrophoresis and Flow Cytometry Systems (2011; $25,000)

 

Other Grant Funding:

● Austin Medical Research Foundation (AMRF) grant: ACE2 therapy for hepatocellular carcinoma (2019; $15,000).

● Faculty of Medicine, Dentistry and Health Sciences (FMDHS), University of Melbourne: Novel therapies for portal hypertension (2019; $45,000).

● Australian Chinese Medical Association (Victoria) research grant. Role of angiotensin peptides in non-alcoholic fatty liver disease (2016; $3000).

● National Research Council (NRC) of Sri Lanka project grant (NRC-045): Sri Lankan indigenous herbal recipes for treatment of liver cirrhosis: Investigation of active compounds present in herbal recipes and medicinal plants (2015-2017; $60,000).

● Austin Medical Research Foundation (AMRF) grant: 2100 Bioanalyzer with Electrophoresis and Flow Cytometry Systems (2012; $10,000).

Austin Medical Research Foundation (AMRF) grant: The role of angiotensin-(1-7) in the development of liver disease and portal hypertension (2010; $10,000).

● Austin Medical Research Foundation (AMRF) grant: Analysis of global gene expression profiles in the liver of patients with fatty liver and non-alcoholic steatohepatitis and the effects of angiotensin II type 1 receptor antagonism (2008; $10,000).

● Japan Science and Technology Agency: Gene expression aberations in cloned bovine fetuses (2003-2004; $100,000).

● Japan Science and Technology Agency: Subtle effects of environmentally persistent estrogen-like chemicals on make and female reproductive physiology (2000-2002; $40,000).

 

 

 

 

 

 

 

 

 

Liver fibrosis and cirrhosis, portal hypertension and novel drug development, novel treatments for biliary and fatty liver disease, diabetes and liver disease